M Petersson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Cardiovascular effects of oxytocin
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Prog Brain Res 139:281-8. 2002
  2. ncbi Oxytocin decreases carrageenan induced inflammation in rats
    M Petersson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Peptides 22:1479-84. 2001
  3. ncbi Oxytocin enhances the effects of clonidine on blood pressure and locomotor activity in rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    J Auton Nerv Syst 78:49-56. 1999
  4. ncbi Oxytocin stimulates proliferation of human osteoblast-like cells
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet and Karolinska Hospital, S 171 76, Stockholm, Sweden
    Peptides 23:1121-6. 2002
  5. ncbi Oxytocin causes a sustained decrease in plasma levels of corticosterone in rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Neurosci Lett 264:41-4. 1999
  6. ncbi Long-term changes in gastrin, cholecystokinin and insulin in response to oxytocin treatment
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Neuroendocrinology 69:202-8. 1999
  7. ncbi Steroid dependent effects of oxytocin on spontaneous motor activity in female rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Brain Res Bull 45:301-5. 1998
  8. ncbi Oxytocin decreases blood pressure in male but not in female spontaneously hypertensive rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    J Auton Nerv Syst 66:15-8. 1997
  9. ncbi Systemic oxytocin treatment modulates glucocorticoid and mineralocorticoid receptor mRNA in the rat hippocampus
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet Karolinska Hospital, S 171 77 Stockholm, Sweden
    Neurosci Lett 343:97-100. 2003
  10. ncbi Prolyl-leucyl-glycinamide shares some effects with oxytocin but decreases oxytocin levels
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet Karolinska Hospital, S 171 76 Stockholm, Sweden
    Physiol Behav 83:475-81. 2004

Collaborators

Detail Information

Publications33

  1. ncbi Cardiovascular effects of oxytocin
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Prog Brain Res 139:281-8. 2002
    ..Oxytocin may also cause cardiovascular effects by affecting other mediators, such as atrial natriuretic peptide (ANP), nitric oxide (NO) and alpha 2-adrenoreceptors...
  2. ncbi Oxytocin decreases carrageenan induced inflammation in rats
    M Petersson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Peptides 22:1479-84. 2001
    ..c.) responded differently to nociceptive mechanical stimulation (P < 0.05) and had a reduced amount of myeloperoxidase (marker for neutrophil recruitment) in the paw (P < 0.01)...
  3. ncbi Oxytocin enhances the effects of clonidine on blood pressure and locomotor activity in rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    J Auton Nerv Syst 78:49-56. 1999
    ..These findings imply that alpha 2-adrenoreceptors are involved in the effects of oxytocin treatment on blood pressure and spontaneous motor activity...
  4. ncbi Oxytocin stimulates proliferation of human osteoblast-like cells
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet and Karolinska Hospital, S 171 76, Stockholm, Sweden
    Peptides 23:1121-6. 2002
    ..Oxytocin 100 pmol/l decreased interleukin-6 (IL-6) production of the hOB cells (23.4+/-1.96 versus 33.4+/-2.65 pg/well; P<0.001). These findings indicate that oxytocin may affect bone metabolism in humans...
  5. ncbi Oxytocin causes a sustained decrease in plasma levels of corticosterone in rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Neurosci Lett 264:41-4. 1999
    ..Dexamethasone decreased corticosterone to equal levels in both groups. Thus, OXT seems to be able to stimulate as well as to inhibit the activity within the HPA-axis within a short- and a long-term perspective, respectively...
  6. ncbi Long-term changes in gastrin, cholecystokinin and insulin in response to oxytocin treatment
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Neuroendocrinology 69:202-8. 1999
    ..These effects may be mediated by changes in vagal nerve activity...
  7. ncbi Steroid dependent effects of oxytocin on spontaneous motor activity in female rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Brain Res Bull 45:301-5. 1998
    ..These results show that the effects of OXY on motor activity in female rats are modified by female sex steroid hormones...
  8. ncbi Oxytocin decreases blood pressure in male but not in female spontaneously hypertensive rats
    M Petersson
    Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    J Auton Nerv Syst 66:15-8. 1997
    ..These results show that oxytocin may cause a sustained decrease in blood pressure, without affecting heart rate, in male but not in female SHR...
  9. ncbi Systemic oxytocin treatment modulates glucocorticoid and mineralocorticoid receptor mRNA in the rat hippocampus
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet Karolinska Hospital, S 171 77 Stockholm, Sweden
    Neurosci Lett 343:97-100. 2003
    ..Thus, oxytocin may modulate the activity of the hypothalamic-pituitary-adrenal-axis also at the hippocampal level in rats...
  10. ncbi Prolyl-leucyl-glycinamide shares some effects with oxytocin but decreases oxytocin levels
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet Karolinska Hospital, S 171 76 Stockholm, Sweden
    Physiol Behav 83:475-81. 2004
    ..In addition, PLG also induced some other effects similar to those induced by oxytocin treatment but when administered in high doses it decreased oxytocin levels...
  11. ncbi Oxytocin/alpha(2)-Adrenoceptor interactions in feeding responses
    Z Diaz-Cabiale
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroendocrinology 71:209-18. 2000
    ....
  12. pmc Generation of CD8+ T cells specific for transporter associated with antigen processing deficient cells
    E Z Wolpert
    Microbiology and Tumor Biology Center, Karolinska Institute, Box 280, S 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 94:11496-501. 1997
    ..These findings are discussed in relation to the biochemical nature of MHC class I dependent CTL epitopes associated with impaired TAP function, as well as implications for immunotherapy and autoimmunity...
  13. ncbi The effects of arg-vasopressin on osteoblast-like cells in endothelial nitric oxide synthase-knockout mice and their wild type counterparts
    A Lagumdzija
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet and Karolinska University Hospital, S 17176 Stockholm, Sweden
    Peptides 26:1661-6. 2005
    ..In conclusion, this study indicates that NO is involved in the effects of AVP on cell proliferation in osteoblast-like cells...
  14. ncbi Antagonistic oxytocin/alpha2-adrenoreceptor interactions in the nucleus tractus solitarii: relevance for central cardiovascular control
    Z Diaz-Cabiale
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    J Neuroendocrinol 12:1167-73. 2000
    ....
  15. ncbi Systemic oxytocin treatment modulates alpha 2-adrenoceptors in telencephalic and diencephalic regions of the rat
    Z Diaz-Cabiale
    Department of Neuroscience BZ lab, Karolinska Institute, S 171 77 Stockholm, Sweden
    Brain Res 887:421-5. 2000
    ..These results suggest that long-term modulation of autonomic and neuroendocrine functions and emotional behaviours elicited by brain oxytocin may involve enhancement of central alpha 2-adrenoceptor function...
  16. ncbi Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10
    F Salazar-Onfray
    Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden
    J Immunol 159:3195-202. 1997
    ....
  17. ncbi Effects of an acute stressor on blood pressure and heart rate in rats pretreated with intracerebroventricular oxytocin injections
    Maria Petersson
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
    Psychoneuroendocrinology 32:959-65. 2007
    ..No such effect was observed in the control group. Thus repeated oxytocin treatment can, in spite of decreasing blood pressure during basal conditions, increase cardiovascular reactivity to some types of stressors...
  18. ncbi Effects of arginine-vasopressin and parathyroid hormone-related protein (1-34) on cell proliferation and production of YKL-40 in cultured chondrocytes from patients with rheumatoid arthritis and osteoarthritis
    M Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet and Karolinska University Hospital, S 171 76 Stockholm, Sweden
    Osteoarthritis Cartilage 14:652-9. 2006
    ..We therefore investigated the effects of AVP and PTHrP (1-34) on cell proliferation and secretion of the glycoprotein YKL-40 in human chondrocytes derived from healthy subjects as well as from patients with RA or osteoarthritis (OA)...
  19. ncbi [Oxytocin, a mediator of anti-stress, well-being, social interaction, growth and healing]
    Kerstin Uvnas-Moberg
    Swedish University of Agricultural Sciences, Department of Animal Physiology, PO Box 7045, S 75007 Uppsala, Sweden
    Z Psychosom Med Psychother 51:57-80. 2005
    ..In addition, various types of psychotherapy involving transfer of support, warmth and empathy are likely to induce similar effects, which thus contribute to the positive effects of these kinds of therapies...
  20. ncbi Oxytocin decreases plasma levels of thyroid-stimulating hormone and thyroid hormones in rats
    Maria Petersson
    Endocrine and Diabetes Unit, Department of Molecular Medicine, Karolinska Institutet, S 171 77, Stockholm, Sweden
    Regul Pept 108:83-7. 2002
    ..c. did not affect plasma levels of TSH, fT3 or fT4. Thus, the effect seems to have been mediated within the central nervous system, and TSH and the thyroid hormones may be involved in some of the metabolic effects in response to oxytocin...
  21. ncbi [Oxytocin--biochemical link for human relations. Mediator of antistress, well-being, social interaction, growth, healing...]
    Kerstin Uvnas-Moberg
    Institutionen för anatomi och fysiologi, Statens Lantbruksuniversitet, Uppsala
    Lakartidningen 101:2634-9. 2004
  22. ncbi Tumor-induced immune dysfunction
    R Kiessling
    Cancer Center Karolinska, Immune and Genetherapy Laboratory, KS ringen R8 01, Karolinska Hospital, S 171 76 Stockholm, Sweden
    Cancer Immunol Immunother 48:353-62. 1999
    ....
  23. ncbi Plasma galanin, vasopressin, and oxytocin in patients with Addison's disease
    E Grenbäck
    Department of Molecular Medicine and Surgery, Endocrine and Diabetes Unit, Karolinska Institutet, Stockholm, Sweden
    Horm Metab Res 39:589-95. 2007
    ..In conclusion, increased plasma ACTH was not reflected in elevated plasma galanin or vasopressin. In contrast, elevated ACTH levels were accompanied by higher oxytocin levels...
  24. ncbi T cell tolerance based on avidity thresholds rather than complete deletion allows maintenance of maximal repertoire diversity
    J K Sandberg
    Microbiology and Tumor Biology Center and Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
    J Immunol 165:25-33. 2000
    ..We interpret these data, together with results previously published by others, in an avidity pit model based on avidity thresholds for maintenance of both maximal diversity and optimal self tolerance in the CD8+ T cell repertoire...
  25. ncbi Arg-vasopressin increases proliferation of human osteoblast-like cells and decreases production of interleukin-6 and macrophage colony-stimulating factor
    Alena Lagumdzija
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet Hospital, S 171 76 Stockholm, Sweden
    Regul Pept 121:41-8. 2004
    ..We suggest that the effect was mediated through the V1-receptor. Additionally, AVP decreased production of IL-6 and M-CSF from the hOB cells. Moreover, the V1a-receptor seems to be expressed in hOB cells...
  26. doi Postnatal oxytocin treatment of spontaneously hypertensive male rats decreases blood pressure and body weight in adulthood
    Maria Petersson
    Department of Molecular Medicine and Surgery, Endocrine and Diabetes Unit, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Neurosci Lett 440:166-9. 2008
    ..128; p=0.10). Heart rate was equal in the two groups. The postnatally oxytocin-treated male SHR had a significantly lower body weight at the age of 5-8 weeks compared to the controls (ANOVA p=0.014)...
  27. ncbi Inhibited anabolic effect of insulin-like growth factor-I on stromal bone marrow cells in endothelial nitric oxide synthase-knockout mice
    A Lagumdzija
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet and Karolinska Hospital, Stockholm, Sweden
    Acta Physiol Scand 182:29-35. 2004
    ..The aim of this study was to investigate whether production of nitric oxide (NO) is involved in the effect of IGF-I and PTH/PTHrP on osteoblast-like cells...
  28. doi Opposite effects of oxytocin on proliferation of osteosarcoma cell lines
    Maria Petersson
    Department of Molecular Medicine and Surgery, Endocrine and Diabetes Unit, Karolinska Institutet Karolinska University Hospital, S 171 76 Stockholm, Sweden
    Regul Pept 150:50-4. 2008
    ..001). Thus oxytocin has the capacity to both stimulate and inhibit cell proliferation of osteosarcoma cells. This effect might be dependent on the stage of differentiation of the cancer cells...
  29. ncbi Oxytocin decreases corticosterone and nociception and increases motor activity in OVX rats
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet Karolinska University Hospital, S 171 77 Stockholm, Sweden
    Maturitas 51:426-33. 2005
    ..c.) or intravaginally (i.vag.) on spontaneous motor activity, nociceptive thresholds and plasma corticosterone levels were examined in female ovariectomized (OVX) rats...
  30. ncbi Oxytocin increases the density of high affinity alpha(2)-adrenoceptors within the hypothalamus, the amygdala and the nucleus of the solitary tract in ovariectomized rats
    Maria Petersson
    Department of Molecular Medicine, Endocrine and Diabetes Unit, Karolinska Institutet Karolinska Hospital, S 171 76 Stockholm, Sweden
    Brain Res 1049:234-9. 2005
    ....
  31. ncbi Peptides associated with hyperphagia in adults with Prader-Willi syndrome before and during GH treatment
    Charlotte Hoybye
    Department of Endocrinology and Diabetology, Karolinska Hospital, Stockholm SE 171 76, Sweden
    Growth Horm IGF Res 13:322-7. 2003
    ..GH treatment of PWS patients did not change ghrelin, leptin or NPY. We suggest that both oxytocin and ghrelin are involved in the pathogenesis of hyperphagia seen in PWS...
  32. ncbi Postnatal oxytocin treatment and postnatal stroking of rats reduce blood pressure in adulthood
    Sarah Holst
    Department of Animal Physiology, Swedish University of Agricultural Sciences, Uppsala
    Auton Neurosci 99:85-90. 2002
    ..No changes in heart rate were found. In conclusion, both postnatal OT treatment and postnatal stroking reduced blood pressure in adulthood. In addition, in female rats, OT reduced the increase in blood pressure caused by prenatal stress...
  33. ncbi Massage-like stroking influences plasma levels of gastrointestinal hormones, including insulin, and increases weight gain in male rats
    Sarah Holst
    Swedish University of Agriculture Sciences, Department of Anatomy and Physiology, P O Box 7045, S 13247 Uppsala, Sweden
    Auton Neurosci 120:73-9. 2005
    ..In conclusion, repeated massage-like stroking decreased plasma levels of gastrin, insulin and somatostatin, increased plasma levels of glucose and promoted weight gain. The effects were influenced by the number of treatments...