Research Topics
| I PerssonSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control studySara Wedren
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Breast Cancer Res 6:R437-49. 2004..Because breast cancer development is dependent on oestrogenic influence, we have investigated whether polymorphisms in the oestrogen receptor alpha gene (ESR1) are associated with breast cancer risk...
Estrogens in the causation of breast, endometrial and ovarian cancers - evidence and hypotheses from epidemiological findingsI Persson
Department of Medical Epidemiology, Karolinska Institutet, 171 77, Stockholm, Sweden
J Steroid Biochem Mol Biol 74:357-64. 2000..Research has yet to define how some of the risk factors can be modified or treatment regimens can be improved to reduce these cancer risks...
Low-potency oestrogen and risk of endometrial cancer: a case-control studyE Weiderpass
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Lancet 353:1824-8. 1999..Although low-potency oestrogen formulations are assumed to have few, if any, adverse effects on the endometrium, risk of endometrial neoplasia has not been quantified...
Body size in different periods of life, diabetes mellitus, hypertension, and risk of postmenopausal endometrial cancer (Sweden)E Weiderpass
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Cancer Causes Control 11:185-92. 2000..To measure the association between endometrial cancer risk and obesity at age 18 and recently, adult weight gain, diabetes mellitus and hypertension...
Risk of endometrial cancer following estrogen replacement with and without progestinsE Weiderpass
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
J Natl Cancer Inst 91:1131-7. 1999..In this study, we examined the endometrial cancer risk associated with combined estrogen-progestin regimens currently in use, since the safety profiles of these regimens have not been clearly defined...
Breast cancer risk and lifetime leisure-time and occupational physical activity (Sweden)T Moradi
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Cancer Causes Control 11:523-31. 2000..To clarify whether type and timing of physical activity affect postmenopausal breast cancer risk...
Body size in different periods of life and breast cancer risk in post-menopausal womenC Magnusson
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Int J Cancer 76:29-34. 1998..Our findings have important implications, suggesting weight preservation as a means for prevention of post-menopausal breast cancer as well as a causal role of childhood body build in breast cancer etiology...
Breast-cancer risk following long-term oestrogen- and oestrogen-progestin-replacement therapyC Magnusson
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Int J Cancer 81:339-44. 1999..Long-term use of replacement oestrogens with or without progestins may substantially increase the incidence of post-menopausal breast cancer, particularly among non-obese women...
Organochlorines and endometrial cancer riskE Weiderpass
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Cancer Epidemiol Biomarkers Prev 9:487-93. 2000..1 (95% confidence interval, 0.6-2.2; P for trend, 0.90). Our data do not support the hypothesis that the organochlorine exposure studied increases the risk for endometrial cancer...
Estrogen receptor alpha gene polymorphisms and endometrial cancer riskE Weiderpass
Department of Medical Epidemiology, Karolinska Institutet, PO Box 281, 171 77 Stockholm, Sweden
Carcinogenesis 21:623-7. 2000..Our data suggest that variants of the ER gene may be associated with an altered risk of endometrial cancer...
Breast cancer following breast reduction surgery in SwedenJ D Boice
International Epidemiology Institute, The Karolinska Institute, Stockholm, Sweden
Plast Reconstr Surg 106:755-62. 2000..The current study is thus consistent with a protective effect following partial removal of breast glandular tissue...
Recent trends in breast cancer incidence in SwedenI Persson
Department of Medical Epidemiology, Karolinska Institute, Stockholm, Sweden
Br J Cancer 77:167-9. 1998..Our data give no indication that use of oral contraceptives or replacement hormones have affected nationwide breast cancer incidence rates...
Endometriosis and the risk of cancer with special emphasis on ovarian cancerA Melin
Department of Obstetrics and Gynaecology, Karolinska University Hospital Huddinge, Stockholm, Sweden
Hum Reprod 21:1237-42. 2006..2 and relative risks for breast cancer, ovarian cancer and non-Hodgkin's lymphoma to be 1.3, 1.9 and 1.8, respectively. The aim of this study was to see whether these risk ratios stand in an extended study with longer follow-up...
Physical activity and postmenopausal endometrial cancer risk (Sweden)T Moradi
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Cancer Causes Control 11:829-37. 2000..To examine the hypothesis that sedentary women have an increased risk of endometrial cancer compared to physically active women...
Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patientsI Persson
Institute of Environmental Medicine, Division of Molecular Toxicology, Karolinska Institutet, Stockholm, Sweden
Int J Cancer 81:325-9. 1999..An increased risk for lung cancer in subjects carrying the HYL*3 allele was observed and suggests that polymorphism in this gene might possibly be a susceptibility factor in the Chinese population...
A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activityC Masimirembwa
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
Br J Clin Pharmacol 42:713-9. 1996..We therefore postulate that the CYP2D6*17 allele might contribute to the molecular basis of the previously established diminished debrisoquine hydroxylase activity in African Bantu populations...
