Nancy L Pedersen

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc IGEMS: the consortium on Interplay of Genes and Environment across Multiple Studies
    Nancy L Pedersen
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 16:481-9. 2013
  2. pmc An unbiased metagenomic search for infectious agents using monozygotic twins discordant for chronic fatigue
    Patrick F Sullivan
    Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Microbiol 11:2. 2011
  3. pmc Accounting for the relationship between low education and dementia: a twin study
    Margaret Gatz
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
    Physiol Behav 92:232-7. 2007
  4. pmc Accuracy and sensitivity of Parkinsonian disorder diagnoses in two Swedish national health registers
    Adina L Feldman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Neuroepidemiology 38:186-93. 2012
  5. pmc Nonstroke cardiovascular disease and risk of Alzheimer disease and dementia
    Ulrika K Eriksson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Alzheimer Dis Assoc Disord 24:213-9. 2010
  6. ncbi request reprint Risk and protective factors for Parkinson's disease: a study in Swedish twins
    Karin Wirdefeldt
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE 181 77 Stockholm, Sweden
    Ann Neurol 57:27-33. 2005
  7. doi request reprint Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?
    Andrea Ganna
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Hum Genet 132:553-61. 2013
  8. doi request reprint Genetic and environmental regulation of inflammatory CVD biomarkers Lp-PLA2 and IgM anti-PC
    Iffat Rahman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 17177 Stockholm, Sweden
    Atherosclerosis 218:117-22. 2011
  9. ncbi request reprint How heritable is Alzheimer's disease late in life? Findings from Swedish twins
    Nancy L Pedersen
    Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Ann Neurol 55:180-5. 2004
  10. ncbi request reprint The association between low birth weight and type 2 diabetes: contribution of genetic factors
    Stefan Johansson
    Departments of Medical Epidemiology, and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Epidemiology 19:659-65. 2008

Collaborators

Detail Information

Publications63

  1. pmc IGEMS: the consortium on Interplay of Genes and Environment across Multiple Studies
    Nancy L Pedersen
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 16:481-9. 2013
    ....
  2. pmc An unbiased metagenomic search for infectious agents using monozygotic twins discordant for chronic fatigue
    Patrick F Sullivan
    Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Microbiol 11:2. 2011
    ..Controls were the unaffected monozygotic co-twins of cases, and serum samples were obtained at the same place and time...
  3. pmc Accounting for the relationship between low education and dementia: a twin study
    Margaret Gatz
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
    Physiol Behav 92:232-7. 2007
    ..Low education is confirmed as a risk factor for dementia. Findings from three different analytic approaches showed that genetic influences did not explain this association...
  4. pmc Accuracy and sensitivity of Parkinsonian disorder diagnoses in two Swedish national health registers
    Adina L Feldman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Neuroepidemiology 38:186-93. 2012
    ..Swedish population-based national health registers are widely used data sources in epidemiological research. Register-based diagnoses of Parkinson's disease have not been validated against clinical information...
  5. pmc Nonstroke cardiovascular disease and risk of Alzheimer disease and dementia
    Ulrika K Eriksson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Alzheimer Dis Assoc Disord 24:213-9. 2010
    ....
  6. ncbi request reprint Risk and protective factors for Parkinson's disease: a study in Swedish twins
    Karin Wirdefeldt
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE 181 77 Stockholm, Sweden
    Ann Neurol 57:27-33. 2005
    ..We confirm the protective effect of smoking on Parkinson's disease and establish that the association is only partially explained by genetic and familial environmental factors...
  7. doi request reprint Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?
    Andrea Ganna
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Hum Genet 132:553-61. 2013
    ..Our findings are compatible with the view of mortality as a complex and highly polygenetic trait, not easily explainable by common genetic variants related to diseases and physiological traits...
  8. doi request reprint Genetic and environmental regulation of inflammatory CVD biomarkers Lp-PLA2 and IgM anti-PC
    Iffat Rahman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 17177 Stockholm, Sweden
    Atherosclerosis 218:117-22. 2011
    ..Their relationships and possible co-regulation with other established CVD biomarkers are also examined...
  9. ncbi request reprint How heritable is Alzheimer's disease late in life? Findings from Swedish twins
    Nancy L Pedersen
    Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Ann Neurol 55:180-5. 2004
    ..Although these genetic estimates for incident disease are lower than those for prevalent disease, the importance of genetic factors for liability to Alzheimer's disease is considerable even late in life...
  10. ncbi request reprint The association between low birth weight and type 2 diabetes: contribution of genetic factors
    Stefan Johansson
    Departments of Medical Epidemiology, and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Epidemiology 19:659-65. 2008
    ..Poor fetal nutrition has been suggested to explain this association. Our objective was to determine whether genetic factors contribute to the association between low birth weight and subsequent risk of type 2 diabetes...
  11. pmc A population-based study of gastroesophageal reflux disease and sleep problems in elderly twins
    Anna Lindam
    Unit of Upper Gastrointestinal Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e48602. 2012
    ..This study aimed to reveal the association between sleep problems and GERD, while adjusting for heredity and other potential confounding factors...
  12. pmc Genetic association of sequence variants near AGER/NOTCH4 and dementia
    Anna M Bennet
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 24:475-84. 2011
    ....
  13. pmc Associations of gene sequence variation and serum levels of C-reactive protein and interleukin-6 with Alzheimer's disease and dementia
    Ulrika K Eriksson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 23:361-9. 2011
    ..However, neither variation in the CRP and IL6 genes nor circulating levels of their respective protein products were associated with an increased risk of developing late-life dementias...
  14. pmc Mid- and late-life diabetes in relation to the risk of dementia: a population-based twin study
    Weili Xu
    Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet and Stockholm Gerontology Research Center, Stockholm, Sweden
    Diabetes 58:71-7. 2009
    ..We aimed to verify the association between diabetes and the risk of dementia, Alzheimer's disease, and vascular dementia in twins and to explore whether genetic and early-life environmental factors could contribute to this association...
  15. ncbi request reprint Genetic and shared environmental factors do not confound the association between birth weight and hypertension: a study among Swedish twins
    Niklas Bergvall
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, SE 171 77 Stockholm, Sweden
    Circulation 115:2931-8. 2007
    ..Studies have found associations between low birth weight and increased risks of cardiovascular diseases in adulthood. However, these associations could be due to confounding by genetic or socioeconomic factors...
  16. doi request reprint Genetic susceptibility of myocardial infarction
    Slobodan Zdravkovic
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 10:848-52. 2007
    ..In conclusion, liability to first occurrence of acute myocardial infarction is moderately influenced by genetic variants in both sexes. The familial influence on phenotypic variance is exclusively explained by additive genetic factors...
  17. pmc Postmenopausal hormone therapy as a risk factor for gastroesophageal reflux symptoms among female twins
    Helena Nordenstedt
    Unit of Esophageal and Gastric Research ESOGAR, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    Gastroenterology 134:921-8. 2008
    ..We investigated the relationship of oral contraceptives and postmenopausal hormone therapy (HT) to risk of reflux symptoms, controlling for genetic factors and body mass...
  18. doi request reprint Heritability of Parkinson disease in Swedish twins: a longitudinal study
    Karin Wirdefeldt
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Neurobiol Aging 32:1923.e1-8. 2011
    ..Concordance rates for PD or parkinsonism were somewhat higher but the heritability estimate was nonsignificant. Our longitudinal analyses demonstrate that PD and parkinsonism are modestly heritable...
  19. ncbi request reprint A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity
    Hagit Katzov
    Center for Genomics and Bioinformatics, Karolinska Institute, Berzelius väg 35 171 77, Stockholm, Sweden
    Hum Mol Genet 13:2647-57. 2004
    ....
  20. ncbi request reprint No evidence for heritability of Parkinson disease in Swedish twins
    Karin Wirdefeldt
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Neurology 63:305-11. 2004
    ..Although several genes are implicated in Parkinson disease (PD), they explain only a small fraction of cases. The etiology of most cases is yet unknown...
  21. ncbi request reprint Self-rated health in a longitudinal perspective: a 9-year follow-up twin study
    Pia Svedberg
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    J Gerontol B Psychol Sci Soc Sci 60:S331-S340. 2005
    ..This study first considers age and cohort explanations for age-related changes in mean values and variance in self-rated health. Second, it evaluates the contributions of genes and environments to self-rated health measured longitudinally...
  22. pmc Genetic and environmental influence on lung function impairment in Swedish twins
    Jenny Hallberg
    Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden
    Respir Res 11:92. 2010
    ..Therefore, the objective was to evaluate heritability for different aspects of lung function, and to investigate how the estimates are affected by adjustments for smoking and respiratory symptoms...
  23. pmc Complete ascertainment of Parkinson disease in the Swedish Twin Registry
    Karin Wirdefeldt
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Neurobiol Aging 29:1765-73. 2008
    ..Overall prevalence rate for PD was 496 per 100,000 individuals. Among the 132 PD cases identified, there were only three concordant twin pairs. In total 7.2% of PD cases reported a first degree relative with PD...
  24. doi request reprint Familial effects on survival after myocardial infarction: a registry-based sib-pair study
    Sara Ekberg
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Nobels vag 12a, Stockholm, Sweden
    Eur J Epidemiol 27:911-4. 2012
    ..This may have important implications for MI prevention strategies but further studies are required to determine if these effects are due to genetic or environmental factors...
  25. ncbi request reprint Obesity and hormone-dependent tumors: cohort and co-twin control studies based on the Swedish Twin Registry
    Fredrik Jonsson
    Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Int J Cancer 106:594-9. 2003
    ..78). No association was found for prostate cancer. We conclude that age is an important effect modifier of cancer risk associated with obesity and that obesity and overweight in young adult life may affect cancer risk also later in life...
  26. pmc Variation in the oxytocin receptor gene is associated with pair-bonding and social behavior
    Hasse Walum
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Biol Psychiatry 71:419-26. 2012
    ..Here we investigate the extent to which genetic variants in the oxytocin receptor gene (OXTR) are associated with pair-bonding and related social behaviors in humans...
  27. ncbi request reprint Premorbid predictors of chronic fatigue
    Kenji Kato
    Department of Medical Epidemiology and Biostatistics, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden
    Arch Gen Psychiatry 63:1267-72. 2006
    ..Moreover, subjects with chronic fatiguing illness may have distinctive personality traits, although this finding could reflect confounding by other mechanisms...
  28. pmc Evidence that the gene encoding insulin degrading enzyme influences human lifespan
    Mun Gwan Hong
    Department of Medical Epidemiology and Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Hum Mol Genet 17:2370-8. 2008
    ....
  29. ncbi request reprint Chronic widespread pain and its comorbidities: a population-based study
    Kenji Kato
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Arch Intern Med 166:1649-54. 2006
    ..Few studies have examined the comorbidities of CWP in the general population. Furthermore, little is known about the importance of familial (genetic and family environmental) factors in the etiology of co-occurrence...
  30. pmc Pleiotropy in the presence of allelic heterogeneity: alternative genetic models for the influence of APOE on serum LDL, CSF amyloid-β42, and dementia
    Anna M Bennet
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 22:129-34. 2010
    ....
  31. doi request reprint Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality
    Fredrik E Wiklund
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Aging Cell 9:1057-64. 2010
    ..Additionally, serum MIC-1/GDF15 levels were directly correlated with survival time independently of genetic background. Serum MIC-1/GDF15 is a novel predictor of all-cause mortality...
  32. doi request reprint The Swedish Twin Registry: establishment of a biobank and other recent developments
    Patrik K E Magnusson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 16:317-29. 2013
    ..Coverage by year of birth, zygosity determination, ethnic heterogeneity, and influences of in vitro fertilization are also described...
  33. ncbi request reprint Asthma, eczema, rhinitis and the risk for dementia
    Ulrika K Eriksson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Dement Geriatr Cogn Disord 25:148-56. 2008
    ..Inflammation is associated with Alzheimer's disease (AD) and dementia. In light of the chronic inflammatory properties of the atopic disorders asthma, eczema and rhinitis, we hypothesized an association with dementia...
  34. pmc Influence of smoking, coffee, and tea consumption on bladder pain syndrome in female twins
    Giorgio Tettamanti
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Urology 77:1313-7. 2011
    ..To assess the influence of smoking, coffee and tea consumption on the risk for bladder pain syndrome (BPS) using the O'Leary Interstitial Cystitis Symptom Index (ICSI)...
  35. ncbi request reprint Sensitivity and specificity of dementia coding in two Swedish disease registries
    Ya Ping Jin
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Neurology 63:739-41. 2004
    ..Specificity was 98% for the Inpatient Discharge Registry and 100% for the Cause of Death Registry...
  36. pmc Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease
    Mun Gwan Hong
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Hum Mutat 33:521-9. 2012
    ....
  37. doi request reprint Differential distribution of subjective and objective cognitive impairment in the population: a nation-wide twin-study
    Barbara Caracciolo
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 29:393-403. 2012
    ..Shared environmental influences rather than genetic background play a role in the occurrence of SCI and CIND...
  38. pmc Lifestyle factors and risk for symptomatic gastroesophageal reflux in monozygotic twins
    Zongli Zheng
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Nobels vag 12a, SE 171 77 Stockholm, Sweden
    Gastroenterology 132:87-95. 2007
    ..We investigated associations between lifestyle factors and gastroesophageal reflux (GER) symptoms, with and without controlling for genetic predisposition...
  39. ncbi request reprint Accounting for depressive symptoms in women: a twin study of associations with interpersonal relationships
    Erica L Spotts
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
    J Affect Disord 82:101-11. 2004
    ..This study examined how interpersonal relationships, specifically marital quality and adequacy of social support, are associated with depressive symptoms among women...
  40. ncbi request reprint The Swedish Twin Registry in the third millennium: an update
    Paul Lichtenstein
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Twin Res Hum Genet 9:875-82. 2006
    ..In particular, we describe recent efforts to screen all twins born between 1959 and 1985, and young twin pairs when they turn 9 and 12 years of age. For these studies, we present initial frequencies of common conditions and exposures...
  41. doi request reprint Genetic dominance influences blood biomarker levels in a sample of 12,000 Swedish elderly twins
    Iffat Rahman
    1 Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Twin Res Hum Genet 12:286-94. 2009
    ..The study highlights the importance of acknowledging nonadditive genes underlying the risk of developing cardiovascular diseases...
  42. doi request reprint Genetic and environmental mediation of the associations between self-rated health and cognitive abilities
    Pia Svedberg
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Exp Aging Res 35:178-201. 2009
    ..In the oldest age group (>or=67 years), associations between self-rated health and spatial reasoning, perceptual speed, and visual memory were entirely due to genetic factors...
  43. ncbi request reprint Bias in variance components due to nonresponse in twin studies
    Annica Dominicus
    Department of Mathematics, Stockholm University, Stockholm, Sweden
    Twin Res Hum Genet 9:185-93. 2006
    ....
  44. doi request reprint Education halves the risk of dementia due to apolipoprotein ε4 allele: a collaborative study from the Swedish brain power initiative
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Caring Sciences, and Society, Karolinska Institutet, Stockholm, Sweden
    Neurobiol Aging 33:1007.e1-7. 2012
    ....
  45. doi request reprint The genetic and environmental contribution to the occurrence of bladder pain syndrome: an empirical approach in a nationwide population sample
    Daniel Altman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 59:280-5. 2011
    ..The importance of genetic factors for BPS is receiving growing attention, but data so far are of a preliminary nature...
  46. ncbi request reprint Likelihood ratio tests in behavioral genetics: problems and solutions
    Annica Dominicus
    Department of Mathematics, Stockholm University, Stockholm, Sweden
    Behav Genet 36:331-40. 2006
    ..Similar results for tests of the AE, DE and E models against the ADE model are also derived. Failing to use the appropriate reference distribution can lead to invalid conclusions...
  47. doi request reprint Risk of urinary incontinence symptoms in oral contraceptive users: a national cohort study from the Swedish Twin Register
    Anastasia Iliadou
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden
    Fertil Steril 92:428-33. 2009
    ..To assess the impact of oral contraceptives on lower urinary tract dysfunction in premenopausal women...
  48. ncbi request reprint Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism
    Hagit Katzov
    Center for Genomics and Bioinformatics, Karolinska Institute, Stockholm, Sweden
    Hum Mutat 23:358-67. 2004
    ..Results indicate that variants of ABCA1 may affect the risk of AD, providing further support for a genetic link between AD and cholesterol metabolism...
  49. ncbi request reprint Lifetime prevalence and concordance risk of cluster headache in the Swedish twin population
    Karl Ekbom
    Department of Neurology, Karolinska Institutet, Stockholm, Sweden
    Neurology 67:798-803. 2006
    ..To examine the lifetime prevalence and the concordance risk of cluster headache (CH) in a twin sample representative of the Swedish general population...
  50. ncbi request reprint Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease
    Mia E L Blomqvist
    Center for Genomics and Bioinformatics, Karolinska Institute, Stockholm, Sweden
    Neurogenetics 5:115-9. 2004
    ..Results were consistent between AD and PD, suggesting the presence of equivalent detrimental and protective alleles. These data highlight a genomic region in the proximity of IDE that may contribute to AD and PD in a similar manner...
  51. ncbi request reprint Importance of genetic influences on chronic widespread pain
    Kenji Kato
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Arthritis Rheum 54:1682-6. 2006
    ..To estimate the relative importance of genetic and environmental factors in chronic widespread pain, and to assess whether there are sex differences in the type or magnitude of these influences...
  52. doi request reprint No evidence of sex differences in heritability of irritable bowel syndrome in Swedish twins
    Pia Svedberg
    Section of Personal Injury Prevention, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 11:197-203. 2008
    ..We found no evidence for sex differences in heritability in any of the age groups, however, models allowing prevalences of irritable bowel syndrome to differ between sexes and age groups fitted best...
  53. ncbi request reprint A prospective study of health, life-style and psychosocial predictors of self-rated health
    Pia Svedberg
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur J Epidemiol 21:767-76. 2006
    ..Genetic and familial factors are of importance only for some of these associations...
  54. ncbi request reprint Genetic influences on angina pectoris and its impact on coronary heart disease
    Slobodan Zdravkovic
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Eur J Hum Genet 15:872-7. 2007
    ..In conclusion, our data imply genetic influences for AP and CHD death among both sexes and that AP is important as a risk factor for CHD death in both males and females, due in part to shared genetic pathways...
  55. doi request reprint Genome-wide search for QTLs for apolipoprotein A-I level in elderly Swedish DZ twins: evidence of female-specific locus on 15q11-13
    Patrik K E Magnusson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur J Hum Genet 16:1103-10. 2008
    ....
  56. doi request reprint Low levels of antibodies against phosphorylcholine in Alzheimer's disease
    Ulrika K Eriksson
    Deparment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden
    J Alzheimers Dis 21:577-84. 2010
    ..Further attention is merited to elucidate the role of anti-PC in AD development and the usefulness of anti-PC as a part of risk prediction, prognosis, diagnosis, or treatment...
  57. pmc Occupational exposure in parkinsonian disorders: a 43-year prospective cohort study in men
    Adina L Feldman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Parkinsonism Relat Disord 17:677-82. 2011
    ..Common findings are increased risk associated with pesticide exposure and no association between Parkinson's disease and welding...
  58. pmc Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humans
    Hasse Walum
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:14153-6. 2008
    ..These results suggest an association between a single gene and pair-bonding behavior in humans, and indicate that the well characterized influence of AVP on pair-bonding in voles may be of relevance also for humans...
  59. ncbi request reprint The epidemiology of chronic fatigue in the Swedish Twin Registry
    Birgitta Evengard
    Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden
    Psychol Med 35:1317-26. 2005
    ..Chronic fatigue syndrome (CFS) remains an idiopathic and controversial entity...
  60. pmc MAOA haplotypes associated with thrombocyte-MAO activity
    Marten Jansson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    BMC Genet 6:46. 2005
    ..3 - 11.4). We performed novel sequencing of the MAO locus and validated genetic variants found in public databases prior to constructing haplotypes of the MAO locus in a Swedish sample (N = 573 individuals)...
  61. ncbi request reprint No linkage to obesity in candidate regions of chromosome 2 and 10 in a selected sample of Swedish twins
    Anastasia Iliadou
    Department of Medical Epidemiology, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden
    Twin Res 6:162-9. 2003
    ..However, the results were sensitive to issues related to power, minor effects of the genes, ethnic differences and the complex mechanism underlying obesity...
  62. pmc The genetic structure of the Swedish population
    Keith Humphreys
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 6:e22547. 2011
    ....
  63. ncbi request reprint Sex differences in genetic risk for dementia
    Margaret Gatz
    University of Southern California, Los Angeles, California, USA Karolinska Institutet, Stockholm, Sweden
    Behav Genet 33:95-105. 2003
    ..We conclude that women are not at higher risk of developing dementia, but there is a hint that different genetic processes may be involved for women than for men...