Markus Moll

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Expansion of CD1d-restricted NKT cells in patients with primary HIV-1 infection treated with interleukin-2
    Markus Moll
    CIM, Department of Medicine, F59, Karolinska Institute, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
    Blood 107:3081-3. 2006
  2. pmc Technical advance. Measurement of iNKT cell responses at the single-cell level against rare HIV-1-infected dendritic cells in a mixed culture
    Sofia K Andersson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Leukoc Biol 93:449-55. 2013
  3. pmc Inhibition of lipid antigen presentation in dendritic cells by HIV-1 Vpu interference with CD1d recycling from endosomal compartments
    Markus Moll
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Blood 116:1876-84. 2010
  4. pmc NKG2D performs two functions in invariant NKT cells: direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d
    Carlotta Kuylenstierna
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Eur J Immunol 41:1913-23. 2011
  5. pmc IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via FcgammaRIIa
    Anna Smed-Sorensen
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Blood 111:5037-46. 2008
  6. doi request reprint Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector- to a memory-type response
    Kim Blom
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden
    J Immunol 190:2150-8. 2013
  7. doi request reprint Expansion of CD56- NK cells in chronic HCV/HIV-1 co-infection: reversion by antiviral treatment with pegylated IFNalpha and ribavirin
    Veronica D Gonzalez
    Center for Infection Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186, Stockholm, Sweden
    Clin Immunol 128:46-56. 2008
  8. pmc Severe functional impairment and elevated PD-1 expression in CD1d-restricted NKT cells retained during chronic HIV-1 infection
    Markus Moll
    Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Eur J Immunol 39:902-11. 2009
  9. pmc HIV-1 Vpu interference with innate cell-mediated immune mechanisms
    Johan K Sandberg
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Curr HIV Res 10:327-33. 2012
  10. pmc Contact-dependent interference with invariant NKT cell activation by herpes simplex virus-infected cells
    Lidija Bosnjak
    Department of Medicine, Center for Infectious Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden
    J Immunol 188:6216-24. 2012

Collaborators

Detail Information

Publications16

  1. pmc Expansion of CD1d-restricted NKT cells in patients with primary HIV-1 infection treated with interleukin-2
    Markus Moll
    CIM, Department of Medicine, F59, Karolinska Institute, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
    Blood 107:3081-3. 2006
    ..These data indicate that IL-2 treatment in combination with effective ART is beneficial for the restoration of innate NKT cell immunity in patients with primary HIV-1 infection...
  2. pmc Technical advance. Measurement of iNKT cell responses at the single-cell level against rare HIV-1-infected dendritic cells in a mixed culture
    Sofia K Andersson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Leukoc Biol 93:449-55. 2013
    ..This microscopy assay, based on full-length HIV-1 modified to express eGFP, thus allows detailed evaluation of HIV-1 immune-evasion mechanisms in rare virus-infected live DCs...
  3. pmc Inhibition of lipid antigen presentation in dendritic cells by HIV-1 Vpu interference with CD1d recycling from endosomal compartments
    Markus Moll
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Blood 116:1876-84. 2010
    ....
  4. pmc NKG2D performs two functions in invariant NKT cells: direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d
    Carlotta Kuylenstierna
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Eur J Immunol 41:1913-23. 2011
    ..NKG2D thus plays both a direct and a co-stimulatory role in the activation of NKT cells...
  5. pmc IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via FcgammaRIIa
    Anna Smed-Sorensen
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Blood 111:5037-46. 2008
    ..Our data demonstrate an important role for FcgammaRIIa in regulating the CD1 antigen presentation machinery of human DCs...
  6. doi request reprint Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector- to a memory-type response
    Kim Blom
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden
    J Immunol 190:2150-8. 2013
    ....
  7. doi request reprint Expansion of CD56- NK cells in chronic HCV/HIV-1 co-infection: reversion by antiviral treatment with pegylated IFNalpha and ribavirin
    Veronica D Gonzalez
    Center for Infection Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186, Stockholm, Sweden
    Clin Immunol 128:46-56. 2008
    ..Together, our data suggest that the high HCV loads in HCV/HIV-1 co-infection alter the NK cell compartment in a way not observed in HCV mono-infection...
  8. pmc Severe functional impairment and elevated PD-1 expression in CD1d-restricted NKT cells retained during chronic HIV-1 infection
    Markus Moll
    Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Eur J Immunol 39:902-11. 2009
    ..The data demonstrate a severe functional impairment in the remaining NKT-cell compartment in HIV-1-infected patients, which limits the prospects to mobilize these cells in immunotherapy approaches in patients...
  9. pmc HIV-1 Vpu interference with innate cell-mediated immune mechanisms
    Johan K Sandberg
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Curr HIV Res 10:327-33. 2012
    ....
  10. pmc Contact-dependent interference with invariant NKT cell activation by herpes simplex virus-infected cells
    Lidija Bosnjak
    Department of Medicine, Center for Infectious Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden
    J Immunol 188:6216-24. 2012
    ..Thus, interference with activation of human iNKT cells by HSV-1 may represent a novel immunoevasive strategy used by the virus to avoid immune clearance...
  11. pmc Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection
    Edwin Leeansyah
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Blood 121:1124-35. 2013
    ....
  12. pmc Application of nine-color flow cytometry for detailed studies of the phenotypic complexity and functional heterogeneity of human lymphocyte subsets
    Veronica D Gonzalez
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Immunol Methods 330:64-74. 2008
    ..We discuss the importance of this technology for detailed investigations of lymphocyte subsets in studies of infectious diseases and cancer...
  13. pmc IVIg immune reconstitution treatment alleviates the state of persistent immune activation and suppressed CD4 T cell counts in CVID
    Dominic Paquin-Proulx
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    PLoS ONE 8:e75199. 2013
    ..These findings help our understanding of the immunopathogenesis of primary immunodeficiency, as well as acquired immunodeficiency caused by HIV-1 infection. ..
  14. doi request reprint IL-18 skews the invariant NKT-cell population via autoreactive activation in atopic eczema
    Sara M Lind
    Clinical Allergy Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    Eur J Immunol 39:2293-301. 2009
    ..Based on these findings, we propose that IL-18-mediated activation and subsequent dysregulation of the CD1d-restricted iNKT-cells plays a role in the pathogenesis of human AE...
  15. ncbi request reprint Effects of interleukin-2 treatment on CD1d-restricted natural killer T cells
    Johan K Sandberg
    Clin Cancer Res 13:4311; author reply 4311-2. 2007
  16. ncbi request reprint Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment
    Einar M Aandahl
    The Biotechnology Centre of Oslo, University of Oslo, Norway
    Blood 104:3672-8. 2004
    ..The results are discussed in relation to the dual roles of CD7 as a receptor of both costimulation and cell death...