J Matthias Lohr

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Rapid progression of a splenic aneurysm due to segmental arterial mediolysis: a rare cause of acute pancreatitis
    J Matthias Lohr
    Gastrocentrum, Karolinska Institute and University Hospital Huddinge, Stockholm, Sweden Dept of Medicine II, University Medical Center Mannheim, University of Heidelberg, Germany Electronic address
    Pancreatology 13:553-6. 2013
  2. doi request reprint Conservative treatment of chronic pancreatitis
    J Matthias Lohr
    Gastroenterology and Hepatology, Gastrocentrum, Karolinska University Hospital, Stockholm, Sweden
    Dig Dis 31:43-50. 2013
  3. pmc 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing
    Paola Longati
    CLINTEC, Karolinska Institutet, Stockholm 14186, Sweden
    BMC Cancer 13:95. 2013
  4. doi request reprint How to cannulate? A survey of the Scandinavian Association for Digestive Endoscopy (SADE) in 141 endoscopists
    J Matthias Lohr
    Gastrocentrum Kirurgi, Karolinska Universitetssjukhuset, Stockholm, Sweden
    Scand J Gastroenterol 47:861-9. 2012
  5. doi request reprint Cationic liposomal paclitaxel plus gemcitabine or gemcitabine alone in patients with advanced pancreatic cancer: a randomized controlled phase II trial
    J M Lohr
    Department of Medicine II, University Hospital Mannheim, Mannheim, Germany
    Ann Oncol 23:1214-22. 2012
  6. doi request reprint Properties of different pancreatin preparations used in pancreatic exocrine insufficiency
    Johannes Matthias Löhr
    Gastrocentrum, Department of Surgical Gastroenterology, Karolinska Institute University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Eur J Gastroenterol Hepatol 21:1024-31. 2009
  7. pmc Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process
    J Matthias Lohr
    Molecular Gastroenterology, German Cancer Research Center, Heidelberg, Germany
    Am J Gastroenterol 105:2060-71. 2010
  8. pmc Extravascular use of drug-eluting beads: a promising approach in compartment-based tumor therapy
    Simon Binder
    Simon Binder, Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany
    World J Gastroenterol 19:7586-93. 2013
  9. doi request reprint ATP-binding cassette C transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells
    Wolfgang Hagmann
    Clinical Cooperation Unit of Molecular Gastroenterology, German Cancer Research Center, Heidelberg, Germany
    Pancreatology 9:136-44. 2009
  10. doi request reprint Comparison of magnetic resonance imaging and video capsule enteroscopy in diagnosing small-bowel pathology: localization-dependent diagnostic yield
    Ulrich Bocker
    University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
    Scand J Gastroenterol 45:490-500. 2010

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Rapid progression of a splenic aneurysm due to segmental arterial mediolysis: a rare cause of acute pancreatitis
    J Matthias Lohr
    Gastrocentrum, Karolinska Institute and University Hospital Huddinge, Stockholm, Sweden Dept of Medicine II, University Medical Center Mannheim, University of Heidelberg, Germany Electronic address
    Pancreatology 13:553-6. 2013
    ..The etiology of acute pancreatitis can be manifold, beside the usual causes. We are reporting an unusual cause that triggered acute pancreatitis...
  2. doi request reprint Conservative treatment of chronic pancreatitis
    J Matthias Lohr
    Gastroenterology and Hepatology, Gastrocentrum, Karolinska University Hospital, Stockholm, Sweden
    Dig Dis 31:43-50. 2013
    ..Because pancreatic surgery has significant morbidity and mortality, less invasive therapy seems to be an attractive option...
  3. pmc 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing
    Paola Longati
    CLINTEC, Karolinska Institutet, Stockholm 14186, Sweden
    BMC Cancer 13:95. 2013
    ..The objective of this study is to develop a simple, high-throughput 3D model of human PDAC cell lines, and to explore mechanisms underlying the transition from 2D to 3D that might be responsible for chemoresistance...
  4. doi request reprint How to cannulate? A survey of the Scandinavian Association for Digestive Endoscopy (SADE) in 141 endoscopists
    J Matthias Lohr
    Gastrocentrum Kirurgi, Karolinska Universitetssjukhuset, Stockholm, Sweden
    Scand J Gastroenterol 47:861-9. 2012
    ..This survey provides us with a database allowing now for a more differentiated view on cannulation techniques, success, and outcome in terms of pancreatitis...
  5. doi request reprint Cationic liposomal paclitaxel plus gemcitabine or gemcitabine alone in patients with advanced pancreatic cancer: a randomized controlled phase II trial
    J M Lohr
    Department of Medicine II, University Hospital Mannheim, Mannheim, Germany
    Ann Oncol 23:1214-22. 2012
    ..This randomized controlled phase II trial evaluated the safety and efficacy of ET in combination with gemcitabine (GEM) in advanced pancreatic cancer (PDAC)...
  6. doi request reprint Properties of different pancreatin preparations used in pancreatic exocrine insufficiency
    Johannes Matthias Löhr
    Gastrocentrum, Department of Surgical Gastroenterology, Karolinska Institute University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Eur J Gastroenterol Hepatol 21:1024-31. 2009
    ..Pancreatic enzyme preparations, generically called pancreatin, are not alike. Rather, they present a broad variety of pancreatin composition...
  7. pmc Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process
    J Matthias Lohr
    Molecular Gastroenterology, German Cancer Research Center, Heidelberg, Germany
    Am J Gastroenterol 105:2060-71. 2010
    ..The objective was to identify novel markers of disease and to unravel the pathogenesis of AIP...
  8. pmc Extravascular use of drug-eluting beads: a promising approach in compartment-based tumor therapy
    Simon Binder
    Simon Binder, Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany
    World J Gastroenterol 19:7586-93. 2013
    ..If CYP2B1 producing cells are proven to be save for usage in man and if local toxic effects of chemotherapeutics can be controlled, DEBs will become promising tools in compartment-based anticancer treatment...
  9. doi request reprint ATP-binding cassette C transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells
    Wolfgang Hagmann
    Clinical Cooperation Unit of Molecular Gastroenterology, German Cancer Research Center, Heidelberg, Germany
    Pancreatology 9:136-44. 2009
    ..We studied ATP-binding cassette (ABC) transporter expression in human pancreatic carcinoma cell lines as compared to primary pancreatic duct cells, and analyzed the MRP expression profile in 5-fluorouracil-resistant cells...
  10. doi request reprint Comparison of magnetic resonance imaging and video capsule enteroscopy in diagnosing small-bowel pathology: localization-dependent diagnostic yield
    Ulrich Bocker
    University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
    Scand J Gastroenterol 45:490-500. 2010
    ....
  11. doi request reprint Transforming growth factor-beta induces nerve growth factor expression in pancreatic stellate cells by activation of the ALK-5 pathway
    Stephan L Haas
    Department of Medicine II, Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Growth Factors 27:289-99. 2009
    ..We conclude that under conditions of upregulated TGF-beta, like fibrosis, NGF levels will also increase in PSC which might contribute to pancreatic wound healing responses...
  12. doi request reprint Coagulation, anticoagulation and pancreatic carcinoma
    Inaam A Nakchbandi
    Max Planck Institute for Biochemistry, Martinsried, Germany and the University of Heidelberg, Heidelberg, Germany
    Nat Clin Pract Gastroenterol Hepatol 5:445-55. 2008
    ..This Review is a critical appraisal of what is known, and when the evidence is acceptable, on the subject of thromboembolism, anticoagulation, and treatment with anticoagulants in patients with pancreatic carcinoma...
  13. doi request reprint Helicobacter pylori in autoimmune pancreatitis and pancreatic carcinoma
    Ralf Jesnowski
    Molecular Gastroenterology G350, DKFZ Heidelberg, Heidelberg, Germany
    Pancreatology 10:462-6. 2010
    ..We investigated the presence of conserved sequences of Helicobacter in pancreatic tissue and pancreatic juice from patients with chronic nonautoimmune and autoimmune pancreatitis as well as pancreatic ductal adenocarcinoma (PDAC)...
  14. ncbi request reprint Bifid tail of the pancreas: benign bifurcation anomaly
    Dietmar Dinter
    Department of Clinical Radiology, University of Heidelberg, University Hospital Mannheim, Theodor Kutzer Ufer 1 3, D 68167 Mannheim, Germany
    AJR Am J Roentgenol 189:W251-3. 2007
  15. doi request reprint Treatment of experimental pancreatic cancer by doxorubicin-, mitoxantrone-, and irinotecan-drug eluting beads
    Vugar Yagublu
    Surgical Clinic, University Medicine Mannheim, Mannheim, Germany
    Pancreatology 13:79-87. 2013
    ....
  16. ncbi request reprint Pancreatic cancer microenvironment
    Jorg Kleeff
    Department of General Surgery, Division of Pancreatic Surgery and Molecular Pancreatic Research, University of Heidelberg, Heidelberg, Germany
    Int J Cancer 121:699-705. 2007
    ..Evidence is accumulating that the cancer microenvironment plays an active role in disease progression, and efforts are being made to target this interplay between cancer cells and host cells to improve the outcome of this deadly disease...
  17. ncbi request reprint Medical treatment of pancreatic cancer
    J Matthias Lohr
    Molekulare Gastroenterologie mit dem Deutschen Krebsforschungszentrum DKFZ G350 II Medizinische Klinik, Medizinische Fakultat Mannheim, Ruprecht Karls Universitat Heidelberg, Mannheim, Germany
    Expert Rev Anticancer Ther 7:533-44. 2007
    ..All aspects of palliative antitumor treatment will be presented in detail and discussed. Finally, some outlooks are given into the future of pancreatic cancer treatment...
  18. ncbi request reprint Expression of tissue factor in pancreatic adenocarcinoma is associated with activation of coagulation
    Stephan L Haas
    Department of Medicine II, University of Heidelberg at Mannheim, D 68167 Mannheim, Germany
    World J Gastroenterol 12:4843-9. 2006
    ..To study expression of tissue factor (TF) in pancreatic cancer and its role in the development of thromboembolism...
  19. ncbi request reprint Microencapsulation of genetically engineered cells for cancer therapy
    J Matthias Lohr
    Department of Molecular Gastroenterology, Medical Clinic II, University of Heidelberg, D 68167 Mannheim, Germany
    Methods Enzymol 346:603-18. 2002
  20. ncbi request reprint What are the useful biological and functional markers of early-stage chronic pancreatitis?
    J Matthias Lohr
    Molecular Gastroenterology Unit dkfz E180, Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, D 68167, Mannheim, Germany
    J Gastroenterol 42:66-71. 2007
    ..It is noteworthy that these markers, present in almost every Asian patient with autoimmune pancreatitis, are mostly lacking in Caucasian populations of patients with autoimmune pancreatitis...