Johanna T Lanner

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Effects of palmitate on Ca(2+) handling in adult control and ob/ob cardiomyocytes: impact of mitochondrial reactive oxygen species
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 56:1136-42. 2007
  2. doi request reprint Ryanodine receptor physiology and its role in disease
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, Von Eulersväg 8, 171 77 Stockholm, Sweden
    Adv Exp Med Biol 740:217-34. 2012
  3. doi request reprint Ca(2+) and insulin-mediated glucose uptake
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Curr Opin Pharmacol 8:339-45. 2008
  4. ncbi request reprint Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Cardiovasc Res 73:376-85. 2007
  5. ncbi request reprint The role of Ca2+ influx for insulin-mediated glucose uptake in skeletal muscle
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77, Stockholm, Sweden
    Diabetes 55:2077-83. 2006
  6. ncbi request reprint Activation of aconitase in mouse fast-twitch skeletal muscle during contraction-mediated oxidative stress
    Shi Jin Zhang
    Dept of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    Am J Physiol Cell Physiol 293:C1154-9. 2007
  7. doi request reprint Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells
    Johanna T Lanner
    Karolinska Institutet, Department of Physiology and Pharmacology, 171 77 Stockholm, Sweden
    FASEB J 23:1728-38. 2009
  8. ncbi request reprint Insulin and inositol 1,4,5-trisphosphate trigger abnormal cytosolic Ca2+ transients and reveal mitochondrial Ca2+ handling defects in cardiomyocytes of ob/ob mice
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 54:2375-81. 2005

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Effects of palmitate on Ca(2+) handling in adult control and ob/ob cardiomyocytes: impact of mitochondrial reactive oxygen species
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 56:1136-42. 2007
    ..Conversely, high fatty acid levels may be vital to sustain cardiac Ca(2+) handling and contraction in obesity and insulin-resistant conditions...
  2. doi request reprint Ryanodine receptor physiology and its role in disease
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, Von Eulersväg 8, 171 77 Stockholm, Sweden
    Adv Exp Med Biol 740:217-34. 2012
    ..This article discusses the physiological function of RyR and examines its role in disorders and diseases...
  3. doi request reprint Ca(2+) and insulin-mediated glucose uptake
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Curr Opin Pharmacol 8:339-45. 2008
    ..No Ca(2+) sensor in this process has yet been explicitly identified but recent studies point at synaptotagmin VII and the motor protein Myo1c as possible candidates...
  4. ncbi request reprint Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Cardiovasc Res 73:376-85. 2007
    ..In the present study we measured non-selective cation currents (NSCC) focusing on the interaction between insulin, the bioactive lipid diacylglycerol (DAG) and canonical transient receptor potential 3 (TRPC3) channels...
  5. ncbi request reprint The role of Ca2+ influx for insulin-mediated glucose uptake in skeletal muscle
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77, Stockholm, Sweden
    Diabetes 55:2077-83. 2006
    ..Moreover, the present results indicate that Ca(2+) acts late in the insulin signaling pathway, for instance, in the GLUT4 translocation to the plasma membrane...
  6. ncbi request reprint Activation of aconitase in mouse fast-twitch skeletal muscle during contraction-mediated oxidative stress
    Shi Jin Zhang
    Dept of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    Am J Physiol Cell Physiol 293:C1154-9. 2007
    ..During contraction, a ROS-mediated inactivation of aconitase can be overcome, possibly by dephosphorylation of the enzyme. The dual-control system may be important in maintaining aerobic ATP production during muscle contraction...
  7. doi request reprint Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells
    Johanna T Lanner
    Karolinska Institutet, Department of Physiology and Pharmacology, 171 77 Stockholm, Sweden
    FASEB J 23:1728-38. 2009
    ..Thus, TRPC3 is a potential target for treatment of insulin-resistant conditions...
  8. ncbi request reprint Insulin and inositol 1,4,5-trisphosphate trigger abnormal cytosolic Ca2+ transients and reveal mitochondrial Ca2+ handling defects in cardiomyocytes of ob/ob mice
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 54:2375-81. 2005
    ..This, together with an impaired mitochondrial Ca2+ handling, results in insulin-mediated extra Ca2+ transients in ob/ob cardiomyocytes that may predispose for arrhythmias in vivo...