Mikael Landen

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Incidence of sexual side effects in refractory depression during treatment with citalopram or paroxetine
    Mikael Landen
    Section of Psychiatry St Göran, Department of Clinical Neuroscience, Karolinska Institutet, SE 112 81, Stockholm, Sweden
    J Clin Psychiatry 66:100-6. 2005
  2. ncbi Placebo-controlled trial comparing intermittent and continuous paroxetine in premenstrual dysphoric disorder
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry St Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 32:153-61. 2007
  3. ncbi [Affective disorders differ in women and men. Not only prevalence but also symptoms and treatment outcome seem to be different]
    Mikael Landen
    Karolinska Institutet, sektionen för psykiatri S t Göran, Stockholm
    Lakartidningen 104:29-31. 2007
  4. doi Short onset of action of a serotonin reuptake inhibitor when used to reduce premenstrual irritability
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry S t Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 34:585-92. 2009
  5. pmc Cognitive manic symptoms in bipolar disorder associated with polymorphisms in the DAOA and COMT genes
    Dzana Sudic Hukic
    Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e67450. 2013
  6. pmc P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1
    Lena Backlund
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e43057. 2012
  7. doi The societal cost of bipolar disorder in Sweden
    Mattias Ekman
    OptumInsight, Stockholm, Sweden
    Soc Psychiatry Psychiatr Epidemiol 48:1601-10. 2013
  8. pmc Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Br J Psychiatry 203:103-6. 2013
  9. doi Mental illness, suicide and creativity: 40-year prospective total population study
    Simon Kyaga
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden
    J Psychiatr Res 47:83-90. 2013
  10. doi Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder
    Anette G M Johansson
    Division of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Eur Neuropsychopharmacol 22:632-40. 2012

Collaborators

Detail Information

Publications25

  1. ncbi Incidence of sexual side effects in refractory depression during treatment with citalopram or paroxetine
    Mikael Landen
    Section of Psychiatry St Göran, Department of Clinical Neuroscience, Karolinska Institutet, SE 112 81, Stockholm, Sweden
    J Clin Psychiatry 66:100-6. 2005
    ....
  2. ncbi Placebo-controlled trial comparing intermittent and continuous paroxetine in premenstrual dysphoric disorder
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry St Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 32:153-61. 2007
    ..Symptoms such as irritability, affect lability, and mood swings appear to be more inclined to respond rapidly to SRIs, enabling intermittent treatment, than are, for example, the somatic symptoms...
  3. ncbi [Affective disorders differ in women and men. Not only prevalence but also symptoms and treatment outcome seem to be different]
    Mikael Landen
    Karolinska Institutet, sektionen för psykiatri S t Göran, Stockholm
    Lakartidningen 104:29-31. 2007
  4. doi Short onset of action of a serotonin reuptake inhibitor when used to reduce premenstrual irritability
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry S t Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 34:585-92. 2009
    ..To summarize, this controlled trial shows that an SRI reduces premenstrual irritability already within a few days after the onset of treatment...
  5. pmc Cognitive manic symptoms in bipolar disorder associated with polymorphisms in the DAOA and COMT genes
    Dzana Sudic Hukic
    Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e67450. 2013
    ..Dopamine and glutamate are important for cognitive processing, thus the COMT and DAOA genes that modulate the expression of these neurotransmitters are of interest for studies of cognitive function...
  6. pmc P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1
    Lena Backlund
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e43057. 2012
    ..We hypothesized that the P2RX7 gene would be affected by sleep deprivation and be implicated in rapid cycling...
  7. doi The societal cost of bipolar disorder in Sweden
    Mattias Ekman
    OptumInsight, Stockholm, Sweden
    Soc Psychiatry Psychiatr Epidemiol 48:1601-10. 2013
    ..The purpose of this study was to estimate the societal cost of bipolar disorder and to relate costs to disease severity, depressive episodes, hospitalisation and patient functioning...
  8. pmc Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Br J Psychiatry 203:103-6. 2013
    ..Attention-deficit hyperactivity disorder (ADHD) is associated with bipolar disorder and schizophrenia, and it has been suggested that combined bipolar disorder and ADHD is aetiologically distinct from the pure disorders...
  9. doi Mental illness, suicide and creativity: 40-year prospective total population study
    Simon Kyaga
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden
    J Psychiatr Res 47:83-90. 2013
    ..We discuss the findings in relationship to some of the major components of creativity...
  10. doi Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder
    Anette G M Johansson
    Division of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Eur Neuropsychopharmacol 22:632-40. 2012
    ..31 (95% CI 0.10-0.96)) but did not correlate with hormone concentrations. Hence, gene variants in the steroidogenetic pathway and steroids concentration differences may be involved in the susceptibility to paranoia during mood elevation...
  11. doi Microparticles and microscopic structures in three fractions of fresh cerebrospinal fluid in schizophrenia: case report of twins
    Fariborz Mobarrez
    Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Cardiovascular Medicine, Stockholm, Sweden
    Schizophr Res 143:192-7. 2013
    ..Such MPs can be investigated for both human and non-human DNA, RNA and microRNA that may activate different immune signaling systems in patients with schizophrenia...
  12. ncbi Vertex-based morphometry in euthymic bipolar disorder implicates striatal regions involved in psychomotor function
    Benny Liberg
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Electronic address
    Psychiatry Res 221:173-8. 2014
    ..It may be that other brain regions sustain the psychomotor functions that produce nearly identical motor performance in both groups. ..
  13. pmc Microscopic particles in two fractions of fresh cerebrospinal fluid in twins with schizophrenia or bipolar disorder and in healthy controls
    Viktoria Johansson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e45994. 2012
    ..This question can be addressed by studying twins discordant or concordant for schizophrenia or bipolar disorder...
  14. doi Cognitive manic symptoms associated with the P2RX7 gene in bipolar disorder
    Lena Backlund
    Department of Clinical Neuroscience Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Bipolar Disord 13:500-8. 2011
    ..Studying associations between bipolar symptoms and candidate genes may better expose this relationship. Here we investigate the association between bipolar key symptoms and the P2RX7 gene...
  15. ncbi Increased psychiatric morbidity in men with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
    Henrik Falhammar
    Department of Endocrinology, Metabolism, and Diabetes H F, Karolinska University Hospital, SE 171 76 Stockholm, Sweden Departments of Molecular Medicine and Surgery H F, An N, and Medical Epidemiology and Biostatistics A B, M L, P L, Karolinska Institutet, SE 171 77 Stockholm, Sweden Department of Child Psychiatry A B, Medical University of Warsaw, 02 091 Warsaw, Poland Institute of Neuroscience and Physiology M L, University of Gothenburg, SE 405 30 Gothenburg, Sweden Department of Women s and Children s Health and Center for Molecular Medicine Ag N, Karolinska Institutet, SE 171 77 Stockholm, Sweden Departments of Pediatric Surgery Ag N, and Pediatric Endocrinology An N, Astrid Lindgren Children Hospital, Karolinska University Hospital, SE 171 76 Stockholm, Sweden Department of Clinical Neuroscience L F, Karolinska Institutet, SE 171 77 Stockholm, Sweden and Child and Adolescent Psychiatry Research Center L F, SE 11330 Stockholm, Sweden
    J Clin Endocrinol Metab 99:E554-60. 2014
    ..Reports on psychiatric morbidity in males with congenital adrenal hyperplasia (CAH) are lacking...
  16. ncbi The societal cost of schizophrenia in Sweden
    Mattias Ekman
    Health Economics and Outcomes Research, OptumInsight, Stockholm, Sweden
    J Ment Health Policy Econ 16:13-25. 2013
    ..Existing cost estimates for Sweden, however, are based on relatively small patient populations and need to be confirmed in a large register-based study...
  17. doi Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder
    Sara K Olsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Bipolar Disord 14:719-26. 2012
    ..Here, we investigate the relationship between symptomatology and the concentration of CSF KYNA in patients with bipolar I disorder...
  18. pmc Leukocyte-derived microparticles and scanning electron microscopic structures in two fractions of fresh cerebrospinal fluid in amyotrophic lateral sclerosis: a case report
    Anne C Zachau
    Karolinska Institutet, Department of Clinical Neuroscience at St, Göran, Stockholm, Sweden
    J Med Case Rep 6:274. 2012
    ..abstract:..
  19. doi Creativity and mental disorder: family study of 300,000 people with severe mental disorder
    Simon Kyaga
    Department of Epidemiology and Biostatistics, Karolinska Institutet, POB 281, SE 171 77 Stockholm, Sweden
    Br J Psychiatry 199:373-9. 2011
    ..There is a long-standing belief that creativity is coupled with psychopathology...
  20. doi Motor imagery in bipolar depression with slowed movement
    Benny Liberg
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Diagnostic Medical Physics, Karolinska University Hospital Huddinge, Stockholm, Sweden Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden Department NVS, Division of Clinical Geriatrics, Karolinska University Hospital, Stockholm, Sweden Department of Clinical Science, Intervention and Technology, Division of Radiology, Karolinska Institutet, Stockholm, Sweden and Department of Energy and Engineering, Swedish University of Agricultural Sciences, Uppsala, Sweden
    J Nerv Ment Dis 201:885-93. 2013
    ..In addition, limbic and prefrontal regions associated with self-reference and the default mode network were altered during motor imagery in bipolar depression with motor retardation. ..
  21. pmc Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder
    Johan Lundberg
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Int J Neuropsychopharmacol 15:1167-72. 2012
    ..5-HTT affinity correlated with the recommended clinical dose. Mirtazapine did not occupy the serotonin transporter. The results support that TCAs and SSRIs have a shared mechanism of action by inhibition of 5-HTT...
  22. doi Sex steroids, insulin sensitivity and sympathetic nerve activity in relation to affective symptoms in women with polycystic ovary syndrome
    Elizabeth Jedel
    Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Psychoneuroendocrinology 36:1470-9. 2011
    ..Further, PCOS is associated with high sympathetic nerve activity...
  23. ncbi AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder
    Anette G M Johansson
    Division of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Affect Disord 133:346-51. 2011
    ....
  24. doi Children's Global Assessment Scale (CGAS) in a naturalistic clinical setting: Inter-rater reliability and comparison with expert ratings
    Anna Lundh
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Psychiatry Res 177:206-10. 2010
    ..Further, the untrained raters differed substantially from the experts. This stresses the importance of proper training in conjunction with the introduction of new rating scales...
  25. doi Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD
    Eleonore Rydén
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Neural Transm 116:1667-74. 2009
    ..This lends biological support to the notion that those with childhood ADHD represent a valid subphenotype of bipolar disorder...