Genomes and Genes


Eva Kosek


Affiliation: Karolinska Institutet
Country: Sweden


  1. Ahmed A, Berg S, Alkass K, Druid H, Hart D, Svensson C, et al. NF-κB-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease. Int J Mol Sci. 2019;20: pubmed publisher
    ..Moreover, NF-κB may be involved in the generation or maintenance of peripheral pain mechanisms by the regulation of pain-related neuropeptide expression in DDD patients. ..
  2. Palada V, Ahmed A, Finn A, Berg S, Svensson C, Kosek E. Characterization of neuroinflammation and periphery-to-CNS inflammatory cross-talk in patients with disc herniation and degenerative disc disease. Brain Behav Immun. 2019;75:60-71 pubmed publisher
  3. Albrecht D, Forsberg A, Sandstrom A, Bergan C, Kadetoff D, Protsenko E, et al. Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation. Brain Behav Immun. 2019;75:72-83 pubmed publisher
    ..Overall, our data support glial modulation as a potential therapeutic strategy for FM. ..
  4. Kosek E, Altawil R, Kadetoff D, Finn A, Westman M, Le Maître E, et al. Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain--interleukin-8 in fibromyalgia and interleukin-1 β in rheumatoid arthritis. J Neuroimmunol. 2015;280:49-55 pubmed publisher
    ..In conclusion, we found different profiles of central cytokines, i.e., elevated IL-1β in inflammatory pain (RA) and elevated IL-8 in dysfunctional pain (FM). ..
  5. Stensson N, Ghafouri N, Ernberg M, Mannerkorpi K, Kosek E, Gerdle B, et al. The Relationship of Endocannabinoidome Lipid Mediators With Pain and Psychological Stress in Women With Fibromyalgia: A Case-Control Study. J Pain. 2018;19:1318-1328 pubmed publisher
    ..The lipids' suitability to work as biomarkers for FM in the clinic were low; however, their altered levels indicate that a metabolic asymmetry is ongoing in FM, which could serve as a baseline during explorative FM pain management. ..
  6. Kosek E, Finn A, Ultenius C, Hugo A, Svensson C, Ahmed A. Differences in neuroimmune signalling between male and female patients suffering from knee osteoarthritis. J Neuroimmunol. 2018;321:49-60 pubmed publisher
  7. Kosek E, Martinsen S, Gerdle B, Mannerkorpi K, Löfgren M, Bileviciute Ljungar I, et al. The translocator protein gene is associated with symptom severity and cerebral pain processing in fibromyalgia. Brain Behav Immun. 2016;58:218-227 pubmed publisher
    ..Furthermore, the functional magnetic resonance findings indicated an effect of translocator protein on the affective-motivational components of pain perception. ..
  8. Larsson A, Palstam A, Löfgren M, Ernberg M, Bjersing J, Bileviciute Ljungar I, et al. Resistance exercise improves muscle strength, health status and pain intensity in fibromyalgia--a randomized controlled trial. Arthritis Res Ther. 2015;17:161 pubmed publisher identification number: NCT01226784, Oct 21, 2010. ..