Torkel Klingberg

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Development of a superior frontal-intraparietal network for visuo-spatial working memory
    Torkel Klingberg
    Paediatric Neurology, Karolinska Institute, Astrid Lindgren s Children s Hospital Q2 07, Stockholm, Sweden
    Neuropsychologia 44:2171-7. 2006
  2. doi request reprint Training and plasticity of working memory
    Torkel Klingberg
    Department of Neuroscience, Karolinska Institute, Retzius vag 8, 171 77 Stockholm, Sweden
    Trends Cogn Sci 14:317-24. 2010
  3. doi request reprint Dopamine, working memory, and training induced plasticity: implications for developmental research
    Stina Soderqvist
    Department of Neuroscience and Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden
    Dev Psychol 48:836-43. 2012
  4. ncbi request reprint Stronger synaptic connectivity as a mechanism behind development of working memory-related brain activity during childhood
    Fredrik Edin
    Karolinska Institutet, Stockholm, Sweden
    J Cogn Neurosci 19:750-60. 2007
  5. ncbi request reprint Visuo-spatial working memory span: a sensitive measure of cognitive deficits in children with ADHD
    Helena Westerberg
    Department of Neuropediatrics, Karolinska Institute, Astrid Lindgrens Barnsjukhus Q2 07, 171 76 Stockholm, Sweden
    Child Neuropsychol 10:155-61. 2004
  6. doi request reprint Structural maturation and brain activity predict future working memory capacity during childhood development
    Henrik Ullman
    Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Neurosci 34:1592-8. 2014
  7. doi request reprint Three dyslexia susceptibility genes, DYX1C1, DCDC2, and KIAA0319, affect temporo-parietal white matter structure
    Fahimeh Darki
    Neuroscience Department, Karolinska Institutet, Stockholm, Sweden
    Biol Psychiatry 72:671-6. 2012
  8. ncbi request reprint Maturation of white matter is associated with the development of cognitive functions during childhood
    Zoltan Nagy
    Karolinska Institute, Astrid Lindgren Children s Hospital, Stockholm, Sweden
    J Cogn Neurosci 16:1227-33. 2004
  9. ncbi request reprint Computerized training of working memory in children with ADHD--a randomized, controlled trial
    Torkel Klingberg
    Unit of Neuropediatrics, Department Women and Children s Health, Karolinska Institute, 17176 Stockholm, Sweden
    J Am Acad Child Adolesc Psychiatry 44:177-86. 2005
  10. doi request reprint Changes in cortical dopamine D1 receptor binding associated with cognitive training
    Fiona McNab
    Neuropediatric Unit, Department of Woman and Child Health, Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden
    Science 323:800-2. 2009

Detail Information

Publications33

  1. ncbi request reprint Development of a superior frontal-intraparietal network for visuo-spatial working memory
    Torkel Klingberg
    Paediatric Neurology, Karolinska Institute, Astrid Lindgren s Children s Hospital Q2 07, Stockholm, Sweden
    Neuropsychologia 44:2171-7. 2006
    ..These networks not only consist of cortical areas but also the white matter tracts connecting them. For visuo-spatial working memory, this network could consist of the superior frontal and intraparietal cortex...
  2. doi request reprint Training and plasticity of working memory
    Torkel Klingberg
    Department of Neuroscience, Karolinska Institute, Retzius vag 8, 171 77 Stockholm, Sweden
    Trends Cogn Sci 14:317-24. 2010
    ..The observed training effects suggest that WM training could be used as a remediating intervention for individuals for whom low WM capacity is a limiting factor for academic performance or in everyday life...
  3. doi request reprint Dopamine, working memory, and training induced plasticity: implications for developmental research
    Stina Soderqvist
    Department of Neuroscience and Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden
    Dev Psychol 48:836-43. 2012
    ..Our results emphasize the importance of the role of dopamine in determining cognitive plasticity...
  4. ncbi request reprint Stronger synaptic connectivity as a mechanism behind development of working memory-related brain activity during childhood
    Fredrik Edin
    Karolinska Institutet, Stockholm, Sweden
    J Cogn Neurosci 19:750-60. 2007
    ....
  5. ncbi request reprint Visuo-spatial working memory span: a sensitive measure of cognitive deficits in children with ADHD
    Helena Westerberg
    Department of Neuropediatrics, Karolinska Institute, Astrid Lindgrens Barnsjukhus Q2 07, 171 76 Stockholm, Sweden
    Child Neuropsychol 10:155-61. 2004
    ..01). Our results show that the VSWM test is a sensitive measure of cognitive deficits in ADHD and it supports the hypothesis that deficits in VSWM is a major component of ADHD...
  6. doi request reprint Structural maturation and brain activity predict future working memory capacity during childhood development
    Henrik Ullman
    Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Neurosci 34:1592-8. 2014
    ..This gives a novel insight into the neural mechanisms of childhood development and supports the idea that neuroimaging can have a unique role in predicting children's cognitive development. ..
  7. doi request reprint Three dyslexia susceptibility genes, DYX1C1, DCDC2, and KIAA0319, affect temporo-parietal white matter structure
    Fahimeh Darki
    Neuroscience Department, Karolinska Institutet, Stockholm, Sweden
    Biol Psychiatry 72:671-6. 2012
    ..Volume and integrity of white matter correlate with reading ability, but the underlying factors contributing to this variability are unknown...
  8. ncbi request reprint Maturation of white matter is associated with the development of cognitive functions during childhood
    Zoltan Nagy
    Karolinska Institute, Astrid Lindgren Children s Hospital, Stockholm, Sweden
    J Cogn Neurosci 16:1227-33. 2004
    ....
  9. ncbi request reprint Computerized training of working memory in children with ADHD--a randomized, controlled trial
    Torkel Klingberg
    Unit of Neuropediatrics, Department Women and Children s Health, Karolinska Institute, 17176 Stockholm, Sweden
    J Am Acad Child Adolesc Psychiatry 44:177-86. 2005
    ..During 2002 to 2003, the authors conducted a multicenter, randomized, controlled, double-blind trial to investigate the effect of improving WM by computerized, systematic practice of WM tasks...
  10. doi request reprint Changes in cortical dopamine D1 receptor binding associated with cognitive training
    Fiona McNab
    Neuropediatric Unit, Department of Woman and Child Health, Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden
    Science 323:800-2. 2009
    ..This plasticity of the dopamine D1 receptor system demonstrates a reciprocal interplay between mental activity and brain biochemistry in vivo...
  11. doi request reprint The SNAP25 gene is linked to working memory capacity and maturation of the posterior cingulate cortex during childhood
    Stina Soderqvist
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Biol Psychiatry 68:1120-5. 2010
    ..Although WM capacity is known to be highly heritable, most genes involved remain unidentified...
  12. doi request reprint Phonological working memory with auditory presentation of pseudo-words -- an event related fMRI Study
    Fredrik Strand
    Neuropediatric Unit, Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    Brain Res 1212:48-54. 2008
    ..Significant activation of the auditory cortex in the middle temporal gyrus was observed during the maintenance phase, which, together with the inferior frontal gyrus activation might underly the maintenance of phonological information...
  13. ncbi request reprint Changes in cortical activity after training of working memory--a single-subject analysis
    Helena Westerberg
    Karolinska Institutet, Department of Neuropediatrics, Stockholm, Sweden
    Physiol Behav 92:186-92. 2007
    ....
  14. ncbi request reprint Brain activity related to working memory and distraction in children and adults
    Pernille J Olesen
    Neuropediatric Research Unit, Department of Women and Child Health, Astrid Lindgren s Children s Hospital Q2 07, Karolinska Institutet, 171 76 Stockholm, Sweden
    Cereb Cortex 17:1047-54. 2007
    ..However, distraction activated frontal cortex only in children. The larger frontal activation in response to distracters presented during the delay may explain why children are more susceptible to interfering stimuli...
  15. doi request reprint Influence of the COMT genotype on working memory and brain activity changes during development
    Iroise Dumontheil
    Neuroscience Department, Karolinska Institutet, Retzius vag 8, Stockholm, Sweden
    Biol Psychiatry 70:222-9. 2011
    ..Dopaminergic system changes during adolescence may lead to a reduction of basal dopamine levels, potentially affecting Met allele benefits during development...
  16. doi request reprint Gains in fluid intelligence after training non-verbal reasoning in 4-year-old children: a controlled, randomized study
    Sissela Bergman Nutley
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Dev Sci 14:591-601. 2011
    ..This study shows that it is possible to improve Gf with training, which could have implications for early interventions in children...
  17. ncbi request reprint Combined analysis of DTI and fMRI data reveals a joint maturation of white and grey matter in a fronto-parietal network
    Pernille J Olesen
    Department of Neuropediatrics, Q2 07, Astrid Lindgren s Children s Hospital, Karolinska Institute, S 17176 Stockholm, Sweden
    Brain Res Cogn Brain Res 18:48-57. 2003
    ....
  18. ncbi request reprint Diffusion tensor imaging on teenagers, born at term with moderate hypoxic-ischemic encephalopathy
    Zoltan Nagy
    Department of Woman and Child Health, Neonatal Unit, Astrid Lindgren Children s Hospital Q2 07, Stockholm, Sweden
    Pediatr Res 58:936-40. 2005
    ..These results indicate that even in the absence of such major neurologic impairments as cerebral palsy, moderate HIE causes long term white matter disturbances which are not repaired by adolescence...
  19. ncbi request reprint Increased prefrontal and parietal activity after training of working memory
    Pernille J Olesen
    Karolinska Institute, Department of Neuropediatrics, Astrid Lindgren s Children s Hospital Q2 07, 171 76 Stockholm, Sweden
    Nat Neurosci 7:75-9. 2004
    ..The changes in cortical activity could be evidence of training-induced plasticity in the neural systems that underlie working memory...
  20. doi request reprint Polymorphisms in the dopamine receptor 2 gene region influence improvements during working memory training in children and adolescents
    Stina Soderqvist
    Karolinska Institutet, Stockholm, Sweden
    J Cogn Neurosci 26:54-62. 2014
    ..Moreover, they suggest that dopamine D2 transmission in the BG is a key factor for cognitive plasticity. ..
  21. ncbi request reprint Increased brain activity in frontal and parietal cortex underlies the development of visuospatial working memory capacity during childhood
    Torkel Klingberg
    Department of Neuropediatrics, Astrid Lindgrens Children s Hospital, Karolinska Institute, Stockholm, Sweden
    J Cogn Neurosci 14:1-10. 2002
    ..These frontal and parietal areas are known to be involved in the control of attention and spatial WM. The development of the functionality in these areas may play an important role in cognitive development during childhood...
  22. doi request reprint Measuring working memory capacity with greater precision in the lower capacity ranges
    Sissela Bergman Nutley
    Neuropaediatric Research Unit, Department of Women s and Children s Health, Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden
    Dev Neuropsychol 35:81-95. 2010
    ..Data showed a large variability of difficulty within each level and the factors contributing to this variability were identified. This variability can be used to provide a precise measure of working memory capacity in the lower ranges...
  23. ncbi request reprint Prefrontal cortex and basal ganglia control access to working memory
    Fiona McNab
    Developmental Cognitive Neuroscience, Stockholm Brain Institute, Karolinska Institutet, MR Centrum, Stockholm, Sweden
    Nat Neurosci 11:103-7. 2008
    ....
  24. pmc Mechanism for top-down control of working memory capacity
    Fredrik Edin
    Karolinska Institutet, 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 106:6802-7. 2009
    ..The model provides a mechanistic framework for understanding top-down control of working memory and specifies two different contributions of prefrontal and parietal cortex to working memory capacity...
  25. doi request reprint Training and transfer effects of executive functions in preschool children
    Lisa B Thorell
    Department of Clinical Neuroscience, Stockholm Brain Institute, Karolinska Institutet, Sweden
    Dev Sci 12:106-13. 2009
    ....
  26. ncbi request reprint Fronto-parietal connection asymmetry regulates working memory distractibility
    Fredrik Edin
    School of Computer Science and Communication, Kungliga Tekniska Högskolan, SE 100 44 Stockholm, Sweden
    J Integr Neurosci 6:567-96. 2007
    ..Our results therefore suggest that the previously demonstrated improvement of vsWM performance during development could be due to a shift in the control of the effective balance between the SFS-IPS networks...
  27. doi request reprint Brain activity during a visuospatial working memory task predicts arithmetical performance 2 years later
    Iroise Dumontheil
    Department of Neuroscience, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Cereb Cortex 22:1078-85. 2012
    ..These results demonstrate that neuroimaging data can provide useful information in addition to behavioral assessments and be used to improve the identification of individuals at risk of future low academic performance...
  28. ncbi request reprint Training of working memory in children with ADHD
    Torkel Klingberg
    Department of Neuropediatrics, Karolinska Institute, Stockholm, Sweden
    J Clin Exp Neuropsychol 24:781-91. 2002
    ..The results thus suggest that WM training potentially could be of clinical use for ameliorating the symptoms in ADHD...
  29. ncbi request reprint Preterm children have disturbances of white matter at 11 years of age as shown by diffusion tensor imaging
    Zoltan Nagy
    Neonatal Unit, Karolinska Institutet, Stockholm, Sweden
    Pediatr Res 54:672-9. 2003
    ....
  30. doi request reprint Trade-off between capacity and precision in visuospatial working memory
    Chantal Roggeman
    Karolinska Institute, Stockholm, Sweden
    J Cogn Neurosci 26:211-22. 2014
    ..These results support a two-module model of WM where performance is determined both by storage capacity and by top-down influence, which can vary on a trial-by-trial basis, affecting both the capacity and precision of WM. ..
  31. pmc Computerized training of non-verbal reasoning and working memory in children with intellectual disability
    Stina Soderqvist
    Department of Neuroscience, Karolinska Institutet Stockholm, Sweden Stockholm Brain Institute Stockholm, Sweden
    Front Hum Neurosci 6:271. 2012
    ..Future studies of cognitive training should take into consideration how inter-individual differences in training progress influence transfer effects and further investigate how baseline capacities predict training outcome...
  32. doi request reprint Common and unique components of inhibition and working memory: an fMRI, within-subjects investigation
    Fiona McNab
    Developmental Cognitive Neuroscience Group, Stockholm Brain Institute, Karolinska Institutet, Sweden
    Neuropsychologia 46:2668-82. 2008
    ..These results support the notion that inhibitory and working memory tasks involve common neural components, which may provide a neural basis for the interrelationship between the two systems...
  33. ncbi request reprint Neuronal firing rates account for distractor effects on mnemonic accuracy in a visuo-spatial working memory task
    Julian Macoveanu
    Computational Biology, Department of Physics, Linköping University of Technology, 581 83 Linkoping, Sweden
    Biol Cybern 96:407-19. 2007
    ....