Affiliation: Karolinska Institutet
- Alkasalias T, Alexeyenko A, Hennig K, Danielsson F, Lebbink R, Fielden M, et al. RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo. Proc Natl Acad Sci U S A. 2017;114:E1413-E1421 pubmed publisher..Taken together, our findings in vivo and in vitro indicate that Rho signaling governs the inhibitory effects by fibroblasts on tumor-cell growth. ..
- Darai Ramqvist E, Díaz de Ståhl T, Sandlund A, Mantripragada K, Klein G, Dumanski J, et al. Array-CGH and multipoint FISH to decode complex chromosomal rearrangements. BMC Genomics. 2006;7:330 pubmed..Although our chr3 BAC/PAC array could identify single copy number changes even in pentaploid cells, mpFISH provided a more accurate analysis in the dissection of complex karyotypes at high ploidy levels. ..
- Klein G, Klein E, Kashuba E. Interaction of Epstein-Barr virus (EBV) with human B-lymphocytes. Biochem Biophys Res Commun. 2010;396:67-73 pubmed publisher..We describe a possible growth promoting mechanism in the genesis of Burkitt lymphoma that depends on the presence of EBV. ..
- Alexeyenko A, Alkasalias T, Pavlova T, Szekely L, Kashuba V, Rundqvist H, et al. Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth. J Exp Clin Cancer Res. 2015;34:62 pubmed publisher..We also demonstrated functional congruence between the in vitro and ex vivo models. The microarray data are made available via the Gene Expression Omnibus as GSE57199. ..