Miia Kivipelto

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
    Miia Kivipelto
    Aging Research Center, Division of Geriatric Epidemiology, Neurotec, Karolinska Institutet, Stockholm, Sweden
    Arch Neurol 62:1556-60. 2005
  2. doi Changes in vascular risk factors from midlife to late life and white matter lesions: a 20-year follow-up study
    Miika Vuorinen
    Aging Research Center, NVS, Karolinska Institute, Stockholm, Sweden
    Dement Geriatr Cogn Disord 31:119-25. 2011
  3. doi The effect of midlife physical activity on structural brain changes in the elderly
    Suvi Rovio
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, 11330 Stockholm, Sweden
    Neurobiol Aging 31:1927-36. 2010
  4. doi High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age
    Francesca Mangialasche
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 20:1029-37. 2010
  5. ncbi Work-related physical activity and the risk of dementia and Alzheimer's disease
    Suvi Rovio
    Aging Research Center, NVS, Karolinska Institutet, Stockholm, Sweden
    Int J Geriatr Psychiatry 22:874-82. 2007
  6. doi Insulin levels are decreased in the cerebrospinal fluid of women with prodomal Alzheimer's disease
    Francisco J Gil-Bea
    Department of Neurobiology, Care Sciences and Society, Karolinska Institutet Alzheimer s Disease Research Center, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 22:405-13. 2010
  7. doi Association of blood pressure and hypertension with the risk of Parkinson disease: the National FINRISK Study
    Chengxuan Qiu
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, S 11330 Stockholm, Sweden
    Hypertension 57:1094-100. 2011
  8. ncbi Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders
    Marjan Shafaati
    Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Neurosci Lett 425:78-82. 2007
  9. doi Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study
    Miia Kivipelto
    Aging Research Center, NVS, Karolinska Institutet, Stockholm, Sweden
    J Cell Mol Med 12:2762-71. 2008
  10. ncbi Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease
    Suvi Rovio
    Aging Research Center, Division of Geriatric Epidemiology, Neurotec, Karolinska Institutet, Stockholm, Sweden
    Lancet Neurol 4:705-11. 2005

Detail Information

Publications54

  1. ncbi Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
    Miia Kivipelto
    Aging Research Center, Division of Geriatric Epidemiology, Neurotec, Karolinska Institutet, Stockholm, Sweden
    Arch Neurol 62:1556-60. 2005
    ..Vascular risk factors play a role in the development of dementia, including Alzheimer disease (AD). However, little is known about the effect of body mass index and clustering of vascular risk factors on the development of dementia...
  2. doi Changes in vascular risk factors from midlife to late life and white matter lesions: a 20-year follow-up study
    Miika Vuorinen
    Aging Research Center, NVS, Karolinska Institute, Stockholm, Sweden
    Dement Geriatr Cogn Disord 31:119-25. 2011
    ..This study investigated the relation of midlife blood pressure, total cholesterol, body mass index (BMI), their changes over time, apolipoprotein E, and white matter lesions (WML)...
  3. doi The effect of midlife physical activity on structural brain changes in the elderly
    Suvi Rovio
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, 11330 Stockholm, Sweden
    Neurobiol Aging 31:1927-36. 2010
    ..The differences in the GM density localized mainly in frontal lobes. There was no significant association between midlife physical activity and severe WML later in life after full adjustments (OR 4.20, 95% CI 0.26-69.13, p=0.32)...
  4. doi High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age
    Francesca Mangialasche
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 20:1029-37. 2010
    ..The neuroprotective effect of vitamin E seems to be related to the combination of different forms, rather than to alpha-tocopherol alone, whose efficacy in interventions against AD is currently debated...
  5. ncbi Work-related physical activity and the risk of dementia and Alzheimer's disease
    Suvi Rovio
    Aging Research Center, NVS, Karolinska Institutet, Stockholm, Sweden
    Int J Geriatr Psychiatry 22:874-82. 2007
    ..This study aimed to clarify the association between work-related physical activity and dementia/AD...
  6. doi Insulin levels are decreased in the cerebrospinal fluid of women with prodomal Alzheimer's disease
    Francisco J Gil-Bea
    Department of Neurobiology, Care Sciences and Society, Karolinska Institutet Alzheimer s Disease Research Center, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 22:405-13. 2010
    ..Furthermore, total-tau/(Aβ1-42*insulin) ratio showed strikingly better sensitivity and specificity than the total-tau/Aβ1-42 ratio for early AD diagnosis in women...
  7. doi Association of blood pressure and hypertension with the risk of Parkinson disease: the National FINRISK Study
    Chengxuan Qiu
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, S 11330 Stockholm, Sweden
    Hypertension 57:1094-100. 2011
    ..Optimal control of blood pressure in women may reduce the incidence of PD...
  8. ncbi Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders
    Marjan Shafaati
    Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Neurosci Lett 425:78-82. 2007
    ..The levels of apoE in cerebrospinal fluid were also correlated to the levels of Tau and the possibility is discussed that the level of apoE in cerebrospinal fluid may be used as a marker of neurodegeneration...
  9. doi Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study
    Miia Kivipelto
    Aging Research Center, NVS, Karolinska Institutet, Stockholm, Sweden
    J Cell Mol Med 12:2762-71. 2008
    ..The apoE epsilon4 carriers may be more vulnerable to environmental factors, and thus, lifestyle interventions may greatly modify dementia risk particularly among the genetically susceptible individuals...
  10. ncbi Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease
    Suvi Rovio
    Aging Research Center, Division of Geriatric Epidemiology, Neurotec, Karolinska Institutet, Stockholm, Sweden
    Lancet Neurol 4:705-11. 2005
    ..The aim of our study was to investigate the association between leisure-time physical activity at midlife and the subsequent development of dementia and Alzheimer's disease (AD)...
  11. ncbi Alcohol drinking and cognitive functions: findings from the Cardiovascular Risk Factors Aging and Dementia (CAIDE) Study
    Tiia Ngandu
    Aging Research Center ARC, Karolinska Institutet, Stockholm, Sweden
    Dement Geriatr Cogn Disord 23:140-9. 2007
    ..Little is known about the effects of midlife alcohol drinking on the cognitive functions later in life...
  12. doi Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults
    Francesca Mangialasche
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy Electronic address
    Exp Gerontol 48:1428-35. 2013
    ..Vitamin E includes eight natural antioxidant compounds (four tocopherols and four tocotrienols), but α-tocopherol has been the main focus of investigation in studies of cognitive impairment and Alzheimer's disease...
  13. pmc Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study
    Tiia Anttila
    Aging Research Center, Division of Geriatric Epidemiology, Neurotec, Karolinska Institutet, Box 6401, 11382 Stockholm, Sweden
    BMJ 329:539. 2004
    ..To evaluate the relation between midlife alcohol consumption and mild cognitive impairment and dementia in old age, and the possible modification of this relation by apolipoprotein E...
  14. doi Midlife rheumatoid arthritis increases the risk of cognitive impairment two decades later: a population-based study
    Karin Wallin
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 31:669-76. 2012
    ..Given the chronic inflammatory component of RA, this study suggests that inflammatory mechanisms may have an important role in increasing the risk of cognitive impairment and dementia/AD...
  15. doi Risk factors for incident dementia in the very old
    Karin Wallin
    Aging Research Center ARC, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Int Psychogeriatr 25:1135-43. 2013
    ..This study describes the association of several baseline factors with dementia in participants aged ≥85 years, and investigates factors associated with a higher risk of incident dementia over five years...
  16. ncbi The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): study design and progress
    Miia Kivipelto
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland Aging Research Center, Karolinska Institutet, Stockholm, Sweden Alzheimer s Disease Research Center, Karolinska Institutet, Stockholm, Sweden Electronic address
    Alzheimers Dement 9:657-65. 2013
    ..Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) is a multi-center, randomized, controlled trial ongoing in Finland...
  17. doi HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's disease
    Francisco J Gil-Bea
    Department of Neurobiology, Care Sciences and Society, Karolinska Institutet Alzheimer s Disease Research Center, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 22:829-38. 2010
    ..It is concluded that there is a dysregulation of the hypothalamus-pituitary-adrenal axis in AD that seems to be consequence rather than cause of AD...
  18. ncbi Dementia after age 75: survival in different severity stages and years of life lost
    Debora Rizzuto
    Aging Research Center, Department of Neurobiology, Health Care Sciences and Society, Karolinska Institutet, Gavlegatan 16, 113 30 Stockholm
    Curr Alzheimer Res 9:795-800. 2012
    ..4 for cancer. We found a similar impact of dementia and CVD on survival, but following diagnosis, persons with dementia, and especially women, spent half of their remaining lives in the severe disabling stages of the disease...
  19. ncbi Practical lessons from amyloid immunotherapy trials in Alzheimer disease
    Alina Solomon
    Aging Research Center ARC, Department of Neurobiology, Care Sciences and Society Karolinska Institutet, Stockholm, Sweden
    Curr Alzheimer Res 9:1126-34. 2012
    ..This study investigates practical experiences of staff and participants in immunotherapy RCTs...
  20. doi A prospective study on the development of Alzheimer's disease with regard to thyroid-stimulating hormone and homocysteine
    Sylvia Annerbo
    Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
    Dement Geriatr Cogn Disord 28:275-80. 2009
    ..Our objective was to prospectively investigate the association between tHcy and TSH and the subsequent development of AD...
  21. doi Education halves the risk of dementia due to apolipoprotein ε4 allele: a collaborative study from the Swedish brain power initiative
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Caring Sciences, and Society, Karolinska Institutet, Stockholm, Sweden
    Neurobiol Aging 33:1007.e1-7. 2012
    ....
  22. doi Cost-effectiveness of a health intervention program with risk reductions for getting demented: results of a Markov model in a Swedish/Finnish setting
    Yanlei Zhang
    Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden
    J Alzheimers Dis 26:735-44. 2011
    ..This is a promising outlook for future research on preventive interventions in dementia, emphasizing the need of conducting multi-domain randomized trials...
  23. ncbi Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study
    Miia Kivipelto
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Lancet Neurol 5:735-41. 2006
    ..Several vascular risk factors are associated with dementia. We sought to develop a simple method for the prediction of the risk of late-life dementia in people of middle age on the basis of their risk profiles...
  24. ncbi Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort
    Elisa Neuvonen
    From the Department of Neurology E N, M R, A s, H S, M K, A M T and Institute of Public Health and Clinical Nutrition T L, University of Eastern Finland, Kuopio Aging Research Center A S, M K, Karolinska Institutet and Stockholm University, Sweden Department of Chronic Disease Prevention T N, T L, National Institute for Health and Welfare, Helsinki, Finland Alzheimer Disease Research Center T N, Karolinska Institutet, Stockholm, Sweden Hospital District of North Karelia T L, Joensuu and Department of Neurology H S, Kuopio University Hospital, Finland
    Neurology 82:2205-12. 2014
    ..We investigated the association between late-life cynical distrust and incident dementia and mortality (mean follow-up times of 8.4 and 10.4 years, respectively) in the Cardiovascular Risk Factors, Aging and Dementia Study...
  25. ncbi Validity of dementia and Alzheimer's disease diagnoses in Finnish national registers
    Alina Solomon
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland Aging Research Center, Karolinska Institutet, Stockholm, Sweden Karolinska Institutet Alzheimer Disease Research Center, Stockholm, Sweden Electronic address
    Alzheimers Dement 10:303-9. 2014
    ..We investigated dementia and Alzheimer disease (AD) diagnoses in three national registers in Finland: the Hospital Discharge Register (HDR), the Drug Reimbursement Register, and the Causes of Death Register (CDR)...
  26. pmc Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
    Chengxuan Qiu
    Aging Research Center, Karolinska Institutet Stockholm, Sweden
    Dialogues Clin Neurosci 11:111-28. 2009
    ....
  27. ncbi Serum lipids and hippocampal volume: the link to Alzheimer's disease?
    Henrike Wolf
    Department of Psychiatry, University of Leipzig, Leipzig, Germany
    Ann Neurol 56:745-8. 2004
    ..This is compatible with protective effects of high-density lipoprotein cholesterol on hippocampal atrophy and Alzheimer's disease...
  28. ncbi Memantine offers new possibilities for the treatment of VaD
    Bengt Winblad
    Karolinska Institutet, Neurotec, Division of Geriatric Medicine and Geriatric Epidemiology, Huddinge University Hospital, 141 86 Stockholm, Sweden
    Lancet Neurol 1:469. 2002
  29. doi Tocopherols and tocotrienols plasma levels are associated with cognitive impairment
    Francesca Mangialasche
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Neurobiol Aging 33:2282-90. 2012
    ..Further, both disorders were associated with increased vitamin E damage. Low plasma tocopherols and tocotrienols levels are associated with increased odds of MCI and AD...
  30. pmc Dementia prevention: current epidemiological evidence and future perspective
    Francesca Mangialasche
    Aging Research Center, Department of Neurobiology, Care Sciences and Society NVS, Karolinska Institutet KI Stockholm University, Gävlegatan 16 9th floor SE 113 30, Stockholm, Sweden
    Alzheimers Res Ther 4:6. 2012
    ..Taking a step in this direction, researchers involved in these European RCTs recently started the European Dementia Prevention Initiative, an international collaboration aiming to improve strategies for preventing dementia...
  31. doi Cholesterol-modifying strategies for Alzheimer's disease
    Alina Solomon
    Aging Research Center, Karolinska Institutet, Sweden
    Expert Rev Neurother 9:695-709. 2009
    ....
  32. doi Alzheimer's disease: clinical trials and drug development
    Francesca Mangialasche
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Lancet Neurol 9:702-16. 2010
    ....
  33. ncbi Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment?
    Valerio Leoni
    Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital in Huddinge, Stockholm, Sweden
    Neurosci Lett 397:83-7. 2006
    ..In patients with AD, the percentages of those with increased levels of 24OHC, tau and phospho tau were similar (55-67%). In this pilot study, we discuss the possibility that 24OHC may be a sensitive test for MCI...
  34. ncbi Rethinking the dementia diagnoses in a population-based study: what is Alzheimer's disease and what is vascular dementia?. A study from the kungsholmen project
    Hedda Aguero-Torres
    Aging Research Center ARC, Karolinska Institutet, Stockholm, Sweden
    Dement Geriatr Cogn Disord 22:244-9. 2006
    ..To explore the hypothesis that older adults often are affected by more than one disease, making the differential diagnosis between Alzheimer's disease (AD) and vascular dementia (VaD) difficult...
  35. doi Prevention of Alzheimer's disease: moving backward through the lifespan
    Alina Solomon
    Department of Neurology, University of Eastern Finland, Kuopio, Finland
    J Alzheimers Dis 33:S465-9. 2013
    ....
  36. ncbi High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice
    Atiqur Rahman
    Karolinska Institutet, Neurotec Department, Division of Experimental Geriatrics, Novum, Karolinska University Hospital, SE 14186 Huddinge, Sweden
    FEBS Lett 579:6411-6. 2005
    ..Our results suggest an interaction between dietary and genetic factors in the development of tauopathies, which can be relevant in humans, where the apoE4 isoform could have a lack of function as compared to other isoforms...
  37. doi The International Network on Public Health and Aging (INOPA): introducing a life course perspective to the public health agenda
    Ake Wahlin
    Department of Psychology, Stockholm University, 106 91, Stockholm, Sweden
    J Cross Cult Gerontol 23:97-105. 2008
    ....
  38. ncbi Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease
    Miia Kivipelto
    University of Kuopio, Department of Neuroscience and Neurology, PO Box 1627, 70211 Kuopio, Finland
    Ann Intern Med 137:149-55. 2002
    ..Elevated midlife values for total cholesterol level and blood pressure have been implicated recently as risk factors for Alzheimer disease...
  39. ncbi Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: potential for pharmacological intervention
    Miia Kivipelto
    Department of Neuroscience and Neurology, University of Kuopio, Kuopio, Finland
    CNS Drugs 16:435-44. 2002
    ..Based on these data, we propose that proper, early interventions aimed at reducing these cardiovascular risk factors may have an impact on the future incidence and prevalence of Alzheimer's disease...
  40. ncbi Incidence and risk factors for mild cognitive impairment: a population-based three-year follow-up study of cognitively healthy elderly subjects
    Susanna Tervo
    Department of Neuroscience and Neurology, Brain Research Unit, Clinical Research Centre, Mediteknia, University of Kuopio, Kuopio, Finland
    Dement Geriatr Cogn Disord 17:196-203. 2004
    ..Both the apolipoprotein E (ApoE) epsilon4 allele and vascular factors have been associated with a higher risk for AD, recently they have also been linked to the risk of MCI...
  41. ncbi Hippocampus and entorhinal cortex in mild cognitive impairment and early AD
    Corina Pennanen
    Department of Neuroscience and Neurology, University of Kuopio and Brain Research Unit, Clinical Research Center, Mediteknia, P O Box 1627, FIN 70 211 Kuopio, Finland
    Neurobiol Aging 25:303-10. 2004
    ..Our results suggest that the ERC atrophy precedes hippocampal atrophy in AD. The ERC volume loss is dominant over the hippocampal volume loss in MCI, whereas more pronounced hippocampal volume loss appears in mild AD...
  42. ncbi Utilization of cognitive support in episodic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older
    David Bunce
    Department of Psychology, Goldsmiths College, University of London, London, United Kingdom
    Neuropsychology 18:362-70. 2004
    ..A similar, but nonsignificant, trend was evident in relation to folate. The research is discussed with reference to vulnerability models and genetic influences on brain reserves...
  43. ncbi Acetylcholinesterase and its inhibition in Alzheimer disease
    Roger M Lane
    Novartis Neuroscience, Novartis Pharmaceuticals Corp, East Hanover, NJ 07936 1080, USA
    Clin Neuropharmacol 27:141-9. 2004
    ..If such differences between ChE-Is are shown to have clinical correlates, this may prompt reconsideration of the rationale and expectations of some agents in the long-term management of AD...
  44. ncbi [Genetics of Alzheimer's disease]
    Mikko Hiltunen
    Kuopion yliopisto, Neurologian klinikka, Mediteknia
    Duodecim 120:2425-31. 2004
  45. ncbi MRI of hippocampus and entorhinal cortex in mild cognitive impairment: a follow-up study
    Tero Tapiola
    Department of Neuroscience and Neurology, University of Kuopio, Brain Research Unit, Clinical Research Center, Mediteknia, 70211 Kuopio, Finland
    Neurobiol Aging 29:31-8. 2008
    ..The MTL volumetry helps in identifying among the MCI subjects a group, which is at high risk for developing AD...
  46. ncbi Metabolic syndrome and cognitive function: a population-based follow-up study in elderly women
    Pirjo Komulainen
    Kuopio Research Institute of Exercise Medicine, Department of Physiology, University of Kuopio, Kuopio, Finland
    Dement Geriatr Cogn Disord 23:29-34. 2007
    ..To test the hypothesis that metabolic syndrome predicts cognitive impairment, and to examine the association of single metabolic risk factors with cognitive functioning...
  47. ncbi Carotid intima-media thickness and cognitive function in elderly women: a population-based study
    Pirjo Komulainen
    Kuopio Research Institute of Exercise Medicine, Kuopio, Finland
    Neuroepidemiology 28:207-13. 2007
    ..We investigated whether carotid intima-media thickness (IMT) predicts the risk of cognitive impairment and whether the putative impairment is specific for some cognitive domains...
  48. doi The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics
    Roy W Jones
    RICE The Research Institute for the Care of Older People, Royal United Hospital, Bath, United Kingdom
    Alzheimers Dement 4:145-53. 2008
    ....
  49. pmc Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors
    Raj N Kalaria
    Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK
    Lancet Neurol 7:812-26. 2008
    ..Dementia costs in developing countries are estimated to be US$73 billion yearly, but care demands social protection, which seems scarce in these regions...
  50. doi A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease
    Taru Tukiainen
    Computational Medicine Research Group, Department of Biomedical Engineering and Computational Science, Helsinki University of Technology, P O Box 9203, FI 02015 HUT, Finland
    Biochem Biophys Res Commun 375:356-61. 2008
    ..The analyses also feature the role of elevated glycoproteins in the risk for AD, supporting the view that coexistence of inflammation and the MetS forms a high risk condition for cognitive decline...
  51. pmc Cerebral embolism and Alzheimer's disease
    Miia Kivipelto
    BMJ 332:1104-5. 2006
  52. ncbi Hypertension and white matter lesions of the brain
    Miia Kivipelto
    J Hypertens 20:387-9. 2002
  53. ncbi Statin therapy in Alzheimer's disease
    Miia Kivipelto
    Lancet Neurol 4:521-2. 2005
  54. ncbi Serum high sensitivity C-reactive protein and cognitive function in elderly women
    Pirjo Komulainen
    Kuopio Research Institute of Exercise Medicine, Finland
    Age Ageing 36:443-8. 2007
    ..Inflammation has been linked to cognitive impairment. However, limited data are available on the association between inflammatory markers and cognitive function...