Erik G Jonsson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population
    Peter Saetre
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 159:981-6. 2012
  2. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
  3. doi request reprint DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
    Erik G Jonsson
    HUBIN project, Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Neuropsychobiology 59:142-50. 2009
  4. doi request reprint Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:976-82. 2008
  5. doi request reprint Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers
    Erik G Jonsson
    Department of Clinical Neuroscience, Karolinska Institute and Hospital, Stockholm, Sweden
    J Neural Transm 115:1695-9. 2008
  6. ncbi request reprint Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Prog Neuropsychopharmacol Biol Psychiatry 30:924-33. 2006
  7. doi request reprint Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses
    Erik G Jonsson
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, SE 171 76 Stockholm, Sweden
    Psychiatry Res 187:80-8. 2011
  8. doi request reprint Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 17176 Stockholm, Sweden
    Eur Neuropsychopharmacol 21:700-4. 2011
  9. doi request reprint The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:387-96. 2010
  10. ncbi request reprint NURR1 promoter polymorphisms: Parkinson's disease, schizophrenia, and personality traits
    Andrea Carmine
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 120:51-7. 2003

Collaborators

Detail Information

Publications51

  1. pmc Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population
    Peter Saetre
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 159:981-6. 2012
    ..The present results do not suggest that the investigated MTHFR polymorphism has any significant influence on age at onset of schizophrenia in the Nordic population...
  2. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
    ..Thus, we tested the hypothesis that variants of the glycolytic genes are associated with schizophrenia or at least with gender-associated aspects of the illness...
  3. doi request reprint DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
    Erik G Jonsson
    HUBIN project, Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Neuropsychobiology 59:142-50. 2009
    ....
  4. doi request reprint Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:976-82. 2008
    ..However, when combined with previous studies in meta-analyses there is still evidence for association between the MTHFR C677T polymorphism and schizophrenia. Additional studies are warranted to shed further light on these relationships...
  5. doi request reprint Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers
    Erik G Jonsson
    Department of Clinical Neuroscience, Karolinska Institute and Hospital, Stockholm, Sweden
    J Neural Transm 115:1695-9. 2008
    ..01). The results suggest that BDNF gene variation participates in regulation of norepinephrine turnover rates in the central nervous system of human subjects...
  6. ncbi request reprint Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Prog Neuropsychopharmacol Biol Psychiatry 30:924-33. 2006
    ..Thus, the BDNF gene may confer susceptibility to schizophrenia. Additional studies are warranted to shed further light on this possibility...
  7. doi request reprint Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses
    Erik G Jonsson
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, SE 171 76 Stockholm, Sweden
    Psychiatry Res 187:80-8. 2011
    ..Various factors, including clinician and patient expectations, and specific strengths and limitations of available antipsychotics may account for frequent medication changes over time...
  8. doi request reprint Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 17176 Stockholm, Sweden
    Eur Neuropsychopharmacol 21:700-4. 2011
    ..The results suggest that genetic variation in DTNBP1 gene affects the regulation of dopamine and serotonin turnover in the central nervous system of healthy volunteers...
  9. doi request reprint The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:387-96. 2010
    ....
  10. ncbi request reprint NURR1 promoter polymorphisms: Parkinson's disease, schizophrenia, and personality traits
    Andrea Carmine
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 120:51-7. 2003
    ..We conclude that the identified polymorphic sites in the human NURR1 are unlikely to be involved in conferring susceptibility for SZ or PD in our patient material...
  11. ncbi request reprint Potential genetic variants in schizophrenia: a Bayesian analysis
    Hakan Hall
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    World J Biol Psychiatry 8:12-22. 2007
    ..The results indicate that the Bayesian statistical method gives additional possibilities in the search for risk factors for schizophrenia or other complex disorders...
  12. pmc Monoamine related functional gene variants and relationships to monoamine metabolite concentrations in CSF of healthy volunteers
    Erik G Jonsson
    Department of Clinical Neuroscience, Psychiatry Section, HUBIN project, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 4:4. 2004
    ..CSF monoamine metabolite concentrations are partly determined by genetic influences...
  13. ncbi request reprint Tryptophan hydroxylase-1 gene variants associate with a group of suicidal borderline women
    Ghazal Zaboli
    Psychiatry Section, Department of Clinical Neuroscience, Karolinska Institute and Hospital, Stockholm, Sweden
    Neuropsychopharmacology 31:1982-90. 2006
    ..We conclude that TPH-1 associates with BPD in suicidal women. Our data support the expectation that haplotype analysis is superior to single locus analysis in gene-disease, case-control association studies...
  14. doi request reprint Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Schizophr Res 106:237-41. 2008
    ....
  15. ncbi request reprint No association between a putative functional promoter variant in the dopamine beta-hydroxylase gene and schizophrenia
    Erik G Jonsson
    Department of Clinical Neuroscience, Psychiatry Section, HUBIN project, Karolinska Institute, SE 171 76 Stockholm, Sweden
    Psychiatr Genet 13:175-8. 2003
    ..We attempted to investigate a putative functional promoter polymorphism in the dopamine beta-hydroxylase gene (DBH) for association with schizophrenia...
  16. pmc Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
    Eva Lindholm Carlström
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, Stockholm, Sweden
    Behav Brain Funct 8:24. 2012
    ..In this study, we wanted to elucidate whether SLC6A4 variations is involved in attempted suicide among patients with schizophrenia in a Scandinavian case-control sample...
  17. pmc D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 262:549-56. 2012
    ....
  18. ncbi request reprint Association study of a functional promoter polymorphism in the XBP1 gene and schizophrenia
    Erik G Jonsson
    Department of Clinical Neuroscience, Psychiatry Section, R5 00, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 141:71-5. 2006
    ..It cannot be excluded, however, that the XBP1 polymorphism is involved in schizophrenia in other populations or adds minor susceptibility to the disorder...
  19. ncbi request reprint BDNF gene variants and brain morphology in schizophrenia
    Ingrid Agartz
    Department of Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 141:513-23. 2006
    ..Trends for associations between several polymorphisms/haplotype estimates and MRI volumes were found. BDNF gene variation may influence brain morphology. The effects may be different in patients with schizophrenia and healthy subjects...
  20. ncbi request reprint Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta-analysis
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 119:28-34. 2003
    ..37, df = 1, P < 0.001; OR 1.43, 95% CI 1.16-1.78). The present results support the involvement of the DRD2 gene in the pathogenesis of schizophrenia...
  21. ncbi request reprint Tryptophan hydroxylase-1 gene variants associated with schizophrenia
    Ghazal Zaboli
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute and Hospital, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
    Biol Psychiatry 60:563-9. 2006
    ..Two isoforms are known, TPH-1 and TPH-2. TPH-1 association with schizophrenia is debated...
  22. doi request reprint Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
    Maria Vares
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:610-8. 2010
    ..008). The MTHFR C677T polymorphism may play a role as a modifying factor for age of onset in schizophrenia...
  23. ncbi request reprint Dopamine D3 receptor gene Ser9Gly variant and schizophrenia: association study and meta-analysis
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet, Stockholm, Sweden
    Psychiatr Genet 13:1-12. 2003
    ..To further evaluate the controversial putative association between a Ser9Gly variant in the first exon of the dopamine D3 receptor gene (DRD3) and schizophrenia...
  24. doi request reprint Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Psychiatry Res 180:63-7. 2010
    ..The results suggest that TPH1 gene variation participates in the regulation of serotonin and dopamine turnover rates in the central nervous system of healthy human subjects...
  25. ncbi request reprint The tryptophan hydroxylase (TPH) 2 gene unlike TPH-1 exhibits no association with stress-induced depression
    Rinat Gizatullin
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska University Hospital, SE 17176 Stockholm, Sweden
    J Affect Disord 107:175-9. 2008
    ..Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin (5-HT), and might be related to the pathogenesis of MD. Two isoforms are known, TPH-1 and TPH-2. Their association with MD is still debated...
  26. pmc Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
    Maria Holtze
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    J Psychiatry Neurosci 37:53-7. 2012
    ..This compound is an end-metabolite of the kynurenine pathway, and its formation indirectly depends on the activity of kynurenine 3-monooxygenase (KMO), the enzyme converting kynurenine to 3-hydroxykynurenine...
  27. doi request reprint Early death and CSF monoamine metabolites in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden
    Nord J Psychiatry 65:101-5. 2011
    ....
  28. doi request reprint Diagnostic profile and suicide risk in schizophrenia spectrum disorder
    Johan Reutfors
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Schizophr Res 123:251-6. 2010
    ..Earlier studies of patients with schizophrenia have investigated suicide risk in relation to specific psychiatric symptoms, but it remains to be better understood how suicide risk relates to the diagnostic profile in these patients...
  29. ncbi request reprint Haplotype analysis confirms association of the serotonin transporter (5-HTT) gene with schizophrenia but not with major depression
    Ghazal Zaboli
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:301-7. 2008
    ..No single locus associations were observed. In agreement with published meta-analysis our results indicate that 5-HTT associates with SCZ but not with MDD. It appears that risk for SCZ maps within a specific 5-HTT haplotype block...
  30. ncbi request reprint Association between a promoter dopamine D2 receptor gene variant and the personality trait detachment
    Erik G Jonsson
    Department of Clinical Neuroscience, Psychiatry Section, HUBIN project, Karolinska Institute, Stockholm, Sweden
    Biol Psychiatry 53:577-84. 2003
    ..A putative functional promoter polymorphism in the dopamine D(2) receptor gene (DRD2), -141C ins/del, has been associated with dopamine D(2) receptor density...
  31. doi request reprint Attempted suicide predicts suicide risk in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden
    Nord J Psychiatry 64:68-72. 2010
    ..People with schizophrenia have an increased risk of suicide and attempted suicide is suggested to be an important risk factor...
  32. ncbi request reprint Two NOTCH4 polymorphisms and their relation to schizophrenia susceptibility and different personality traits
    Andrea Carmine
    Department of Neuroscience, Clinical Neurogenetics Unit, Stockholm, Sweden
    Psychiatr Genet 13:23-8. 2003
    ..Recently, linkage disequilibrium mapping of the major histocompatibility complex region on the short arm of human chromosome 6 suggested that the NOTCH4 locus is highly associated with schizophrenia...
  33. doi request reprint Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia
    Katarina Varnas
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Psychiatr Genet 18:177-83. 2008
    ..To investigate associations between brain-derived neurotrophic factor (BDNF) gene polymorphisms and regional frontal cortical thickness and volume in patients with schizophrenia and healthy control participants...
  34. doi request reprint CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital Solna, SE 171 76 Stockholm, Sweden
    Psychiatry Res 205:165-7. 2013
    ..Three patients died from suicide and nine patients had a history of attempted suicide. Patients with attempted suicide had significantly lower concentrations of CSF KYNA...
  35. ncbi request reprint Association between a promoter variant in the monoamine oxidase A gene and schizophrenia
    Erik G Jonsson
    Department of Clinical Neuroscience, Psychiatry Section, HUBIN project, Karolinska Institute and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Schizophr Res 61:31-7. 2003
    ..05). In women, no significant differences were found. The present results support the involvement of the MAOA gene in men with schizophrenia in the investigated Swedish population but should be interpreted with caution until replicated...
  36. pmc Concomitant medication of psychoses in a lifetime perspective
    Maria Vares
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Hum Psychopharmacol 26:322-31. 2011
    ....
  37. ncbi request reprint Characterization of patients with schizophrenia and related psychoses: evaluation of different diagnostic procedures
    Maria Vares
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Psychopathology 39:286-95. 2006
    ..In addition, the validity of the Operational Criteria Checklist (OPCRIT) system was analysed...
  38. doi request reprint Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 156:215-24. 2011
    ..The present results suggest that the investigated MTHFR polymorphisms do not influence age of onset in schizophrenia...
  39. doi request reprint Long-term suicide risk in schizophrenia spectrum psychoses: survival analysis by gender
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry, Karolinska University Hospital Solna, Stockholm, Sweden
    Arch Suicide Res 12:347-51. 2008
    ..These results indicate that patients with schizophrenia spectrum psychoses have a high long term suicide risk in both men and women. The high suicide risk in female patients deserves further research attention...
  40. ncbi request reprint Meta-analysis of the dopamine D3 receptor gene (DRD3) Ser9Gly variant and schizophrenia
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Psychiatr Genet 14:9-12. 2004
  41. ncbi request reprint Altered white matter/gray matter proportions in the striatum of patients with schizophrenia: a volumetric MRI study
    Chiharu Tamagaki
    Human Brain Informatics, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Am J Psychiatry 162:2315-21. 2005
    ..Anatomical structures of the striatum were studied in 58 patients with schizophrenia and 56 healthy comparison subjects of both genders matched for age and handedness...
  42. pmc Morphological correlates to cognitive dysfunction in schizophrenia as studied with Bayesian regression
    Glenn Laywer
    Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden
    BMC Psychiatry 6:31. 2006
    ..This work explored a model encompassing all of these possibilities to identify the strongest morphological relationships to cognitive skill in schizophrenia...
  43. ncbi request reprint Haplotype analysis reveals tryptophan hydroxylase (TPH) 1 gene variants associated with major depression
    Rinat Gizatullin
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute and Hospital, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
    Biol Psychiatry 59:295-300. 2006
    ..Two isoforms are known, TPH-1 and TPH-2. Tryptophan hydroxylase-1 association with MD is still debated...
  44. ncbi request reprint Risk factors for suicide in schizophrenia: findings from a Swedish population-based case-control study
    Johan Reutfors
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Schizophr Res 108:231-7. 2009
    ..In schizophrenia, certain suicide risk factors may differ from those in the general population. Clinical suicide risk assessment for schizophrenia patients should be performed taking this into account...
  45. ncbi request reprint Evaluation of diagnostic procedures in Swedish patients with schizophrenia and related psychoses
    Birgit Ekholm
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, R5 00, SE 171 76, Stockholm, Sweden
    Nord J Psychiatry 59:457-64. 2005
    ..It is concluded that for future Swedish large-scale genetic studies focusing on a broad definition of schizophrenia, it would be sufficient to rely on the Swedish register diagnoses of schizophrenic psychosis...
  46. ncbi request reprint CSF 5-HIAA, attempted suicide and suicide risk in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden
    Schizophr Res 112:80-5. 2009
    ..The objective of this study was to investigate the relationship between levels of CSF 5-HIAA, CSF HVA and suicidal behavior in patients with schizophrenia spectrum psychosis...
  47. ncbi request reprint Association study between dopamine D3 receptor gene variant and personality traits
    Erik G Jonsson
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 117:61-5. 2003
    ..After correction for multiple testing, however, no significant difference remained. We conclude that the investigated DRD3 polymorphism does not have a major impact on personality in the investigated population...
  48. doi request reprint Suicide in schizophrenia
    Andreas Carlborg
    Karolinska University Hospital, Stockholm, Sweden
    Expert Rev Neurother 10:1153-64. 2010
    ..Management of suicide risk includes both medical treatment and psychosocial interventions. Still, risk factors are crude; efforts to predict individual suicides have not proved useful and more research is needed...
  49. pmc Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder
    Sara K Olsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    J Psychiatry Neurosci 35:195-9. 2010
    ..We measured the levels of KYNA in the cerebrospinal fluid (CSF) of patients with bipolar disorder and healthy volunteers to investigate the putative involvement of KYNA in bipolar disorder...
  50. ncbi request reprint Cerebrospinal fluid kynurenic acid in male and female controls - correlation with monoamine metabolites and influences of confounding factors
    Linda K Nilsson
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    J Psychiatr Res 41:144-51. 2007
    ..Furthermore, these findings suggest that increased KYNA formation is associated with an increased dopamine and serotonin turnover...
  51. ncbi request reprint No association between a transcription factor Activating Protein 2beta (AP-2beta) gene variant and schizophrenia
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Psychiatry Section, Karolinska Institute and Hospital, SE 171 76 Stockholm, Sweden
    Neurosci Lett 330:290-2. 2002
    ..We conclude that the investigated AP-2beta variant is not of major importance to schizophrenia in the investigated Swedish population...