Kristina Johnell

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Comparison of prescription drug use between community-dwelling and institutionalized elderly in Sweden
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Drugs Aging 29:751-8. 2012
  2. doi request reprint The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    PLoS ONE 9:e86742. 2014
  3. doi request reprint Managing therapeutic competition in patients with heart failure, lower urinary tract symptoms and incontinence
    Cara Tannenbaum
    Faculties of Medicine and Pharmacy, Universite de Montreal, Montreal, QC, Canada
    Drugs Aging 31:93-101. 2014
  4. doi request reprint Differences in drug therapy between dementia disorders in the Swedish dementia registry: a nationwide study of over 7,000 patients
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, SE 113 30 Stockholm, Sweden
    Dement Geriatr Cogn Disord 35:239-48. 2013
  5. ncbi request reprint Concomitant use of gastroprotective drugs among elderly NSAID/COX-2 selective inhibitor users: a nationwide register-based study
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Clin Drug Investig 28:687-95. 2008
  6. doi request reprint The use of benzodiazpines and related drugs amongst older people in Sweden: associated factors and concomitant use of other psychotropics
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Int J Geriatr Psychiatry 24:731-8. 2009
  7. doi request reprint Sex differences in inappropriate drug use: a register-based study of over 600,000 older people
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Ann Pharmacother 43:1233-8. 2009
  8. doi request reprint Antiepileptic drug use in community-dwelling and institutionalized elderly: a nationwide study of over 1,300,000 older people
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30 Stockholm, Sweden
    Eur J Clin Pharmacol 67:1069-75. 2011
  9. doi request reprint Gender and use of hypnotics or sedatives in old age: a nationwide register-based study
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30, Stockholm, Sweden
    Int J Clin Pharm 33:788-93. 2011
  10. pmc Dopaminergic and serotonergic drug use: a nationwide register-based study of over 1,300,000 older people
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    PLoS ONE 6:e23750. 2011

Detail Information

Publications35

  1. ncbi request reprint Comparison of prescription drug use between community-dwelling and institutionalized elderly in Sweden
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Drugs Aging 29:751-8. 2012
    ..Hence, very few studies have compared drug use in institutionalized and community-dwelling elderly, maybe because of a lack of sufficiently large databases...
  2. doi request reprint The role of marital status in the association between benzodiazepines, psychotropics and injurious road traffic crashes: a register-based nationwide study of senior drivers in Sweden
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    PLoS ONE 9:e86742. 2014
    ..It remains unclear however if BZDs play the same role when considering marital status. Therefore, we aimed to investigate the role of marital status in the association between BZD use and injurious RTCs among senior drivers...
  3. doi request reprint Managing therapeutic competition in patients with heart failure, lower urinary tract symptoms and incontinence
    Cara Tannenbaum
    Faculties of Medicine and Pharmacy, Universite de Montreal, Montreal, QC, Canada
    Drugs Aging 31:93-101. 2014
    ..Compelling strategies to improve urinary outcomes include titrating diuretics, switching ACE inhibitors, treating lower urinary tract infections, appropriate fluid management, daily weighing, and uptake of pelvic floor muscle exercises...
  4. doi request reprint Differences in drug therapy between dementia disorders in the Swedish dementia registry: a nationwide study of over 7,000 patients
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, SE 113 30 Stockholm, Sweden
    Dement Geriatr Cogn Disord 35:239-48. 2013
    ..We aimed to study whether there are differences between dementia disorders and the use of anti-dementia drugs and antipsychotics (neuroleptics) in a large population of dementia patients...
  5. ncbi request reprint Concomitant use of gastroprotective drugs among elderly NSAID/COX-2 selective inhibitor users: a nationwide register-based study
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Clin Drug Investig 28:687-95. 2008
    ....
  6. doi request reprint The use of benzodiazpines and related drugs amongst older people in Sweden: associated factors and concomitant use of other psychotropics
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Int J Geriatr Psychiatry 24:731-8. 2009
    ..To determine the factors associated with use of benzodiazepines and benzodiazepine related drugs (BZDs/BZDRDs) in a nationwide population of older people...
  7. doi request reprint Sex differences in inappropriate drug use: a register-based study of over 600,000 older people
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Ann Pharmacother 43:1233-8. 2009
    ..Also, educational level (a measure of socioeconomic status) has been associated with both polypharmacy and inappropriate drug use in the elderly population, which could explain sex differences in inappropriate drug use...
  8. doi request reprint Antiepileptic drug use in community-dwelling and institutionalized elderly: a nationwide study of over 1,300,000 older people
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30 Stockholm, Sweden
    Eur J Clin Pharmacol 67:1069-75. 2011
    ..e. number of other drugs)...
  9. doi request reprint Gender and use of hypnotics or sedatives in old age: a nationwide register-based study
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30, Stockholm, Sweden
    Int J Clin Pharm 33:788-93. 2011
    ..e., education) and co-morbidity (i.e., number of other drugs)...
  10. pmc Dopaminergic and serotonergic drug use: a nationwide register-based study of over 1,300,000 older people
    Kristina Johnell
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    PLoS ONE 6:e23750. 2011
    ..To investigate the use of dopaminergic and serotonergic drugs in elderly people...
  11. ncbi request reprint Concurrent use of anticholinergic drugs and cholinesterase inhibitors: register-based study of over 700,000 elderly patients
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Drugs Aging 25:871-7. 2008
    ..To the authors' knowledge, use of this inappropriate drug combination has not been studied outside North America...
  12. ncbi request reprint [Low quality of drug use among the elderly. An analysis based on the national drug registry shows regional differences]
    Kristina Johnell
    Lakartidningen 104:2158-62. 2007
  13. doi request reprint The association between use of cardiovascular drugs and antidepressants: a nationwide register-based study
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, 11330 Stockholm, Sweden
    Eur J Clin Pharmacol 64:1119-24. 2008
    ..To investigate whether cardiovascular drug classes and specific beta-blockers are associated with antidepressant drug use in a large study population of older people...
  14. pmc Multi-dose drug dispensing and inappropriate drug use: A nationwide register-based study of over 700,000 elderly
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Scand J Prim Health Care 26:86-91. 2008
    ..To investigate whether the use of multi-dose drug dispensing is associated with potentially inappropriate drug use (IDU)...
  15. ncbi request reprint Education and use of dementia drugs: a register-based study of over 600,000 older people
    Kristina Johnell
    Aging Research Centre, Karolinska Institutet, Stockholm, Sweden
    Dement Geriatr Cogn Disord 25:54-9. 2008
    ..Low education has been shown to be a risk factor for dementia. However, little is known about the association between educational level and dementia drugs...
  16. ncbi request reprint The relationship between number of drugs and potential drug-drug interactions in the elderly: a study of over 600,000 elderly patients from the Swedish Prescribed Drug Register
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Drug Saf 30:911-8. 2007
    ..In addition, many DDIs are regarded as predictable and avoidable; therefore, they may be considered as targets for education and interventions...
  17. pmc Individual characteristics, area social participation, and primary non-concordance with medication: a multilevel analysis
    Kristina Johnell
    Centre for Family Medicine, Karolinska Institutet, Stockholm, Sweden
    BMC Public Health 6:52. 2006
    ..Our second aim is to investigate whether people living in the same area have similar probability of primary non-concordance with medication, that relates to area social participation...
  18. ncbi request reprint Inappropriate drug use in the elderly: a nationwide register-based study
    Kristina Johnell
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Ann Pharmacother 41:1243-8. 2007
    ..Potentially inappropriate drug use (IDU) is an important and preventable safety concern in the care of elderly patients and has been associated with adverse drug reactions, hospitalization, and mortality...
  19. doi request reprint Different patterns in use of antibiotics for lower urinary tract infection in institutionalized and home-dwelling elderly: a register-based study
    Ylva Haasum
    Aging Research Center, Department of Neurobiology, Care Sciences and Society NVS, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30 Stockholm, Sweden
    Eur J Clin Pharmacol 69:665-71. 2013
    ..We compared the quality and pattern of use of antibiotics to treat urinary tract infection (UTI) between institutionalized and home-dwelling elderly...
  20. doi request reprint Drug use in centenarians compared with nonagenarians and octogenarians in Sweden: a nationwide register-based study
    Jonas W Wastesson
    Aging Research Center, Karolinska Institutet and Stockholm University, Gavlegatan 16, SE 113 30 Stockholm, Sweden
    Age Ageing 41:218-24. 2012
    ..the number of centenarians increases rapidly. Yet, little is known about their health and use of medications...
  21. doi request reprint Institutionalization as a risk factor for inappropriate drug use in the elderly: a Swedish nationwide register-based study
    Ylva Haasum
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm Gerontology Research Center, Stockholm, Sweden
    Ann Pharmacother 46:339-46. 2012
    ..Sweden now has unique possibilities for comparisons of drug use in large populations of institutionalized and home-dwelling elderly through linkage of the Swedish Prescribed Drug Register (SPDR) with the Swedish Social Services Register...
  22. ncbi request reprint Anxiolytic-hypnotic drug use associated with trust, social participation, and the miniaturization of community: a multilevel analysis
    Kristina Johnell
    Center for Family Medicine, Karolinska Institute, Stockholm, Sweden
    Soc Sci Med 62:1205-14. 2006
    ..The concept of miniaturization of community may be an extension of the classic concept of social capital and may increase our understanding of contextual effects on health...
  23. doi request reprint The influence of educational level on polypharmacy and inappropriate drug use: a register-based study of more than 600,000 older people
    Syed Imran Haider
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    J Am Geriatr Soc 57:62-9. 2009
    ..To investigate whether low educational attainment is associated with polypharmacy and potential inappropriate drug use (IDU) in older people...
  24. doi request reprint Analysis of the association between polypharmacy and socioeconomic position among elderly aged > or =77 years in Sweden
    Syed Imran Haider
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Clin Ther 30:419-27. 2008
    ..However, few studies have analyzed the association between socioeconomic position (SEP) and the extent of drug use in older people...
  25. ncbi request reprint Neighborhood social participation, use of anxiolytic-hypnotic drugs, and women's propensity for disability pension: a multilevel analysis
    Kristina Johnell
    Centre for Family Medicine, Karolinska Institutet, Huddinge, Sweden
    Scand J Public Health 34:41-8. 2006
    ....
  26. doi request reprint Patient educational level and use of newly marketed drugs: a register-based study of over 600,000 older people
    Syed Imran Haider
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, 11330 Stockholm, Sweden
    Eur J Clin Pharmacol 64:1215-22. 2008
    ..To examine the association between educational level and the use of newly marketed drugs (NMD) among elderly persons...
  27. pmc Low adherence with antihypertensives in actual practice: the association with social participation--a multilevel analysis
    Kristina Johnell
    Centre for Family Medicine, Karolinska Institutet, Huddinge, Sweden
    BMC Public Health 5:17. 2005
    ..The purpose of this study is to examine whether low social participation is associated with low adherence with antihypertensive medication, and if this association is modified by the municipality of residence...
  28. pmc Dementia management programme in a community setting and the use of psychotropic drugs in the elderly population
    Erik Jedenius
    Department of Neurobiology, Care Sciences and Society, Karolinska Institutet Alzheimer Disease Research Centre, Stockholm, Sweden
    Scand J Prim Health Care 29:181-6. 2011
    ..The objective of the present study is to evaluate whether the dementia programme had a secondary effect on the use of psychotropic medication in the elderly population in general...
  29. ncbi request reprint Mortality and treatment costs have a great impact on the cost-effectiveness of disease modifying treatment in Alzheimer's disease--a simulation study
    Anders Sköldunger
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Curr Alzheimer Res 10:207-16. 2013
    ..It is of vital importance to develop and identify cost effective treatment. The aim of the study was to present a hypothetical economic model of Disease Modifying Treatment (DMT) in AD...
  30. pmc Is drug treatment for dementia followed up in primary care? A Swedish study of dementia clinics and referring primary care centres
    Lars Sonde
    FOU nu Research and Development Centre, Stockholm, Sweden
    PLoS ONE 8:e57161. 2013
    ..It is largely unknown how the medical treatment of patients diagnosed with dementia is followed up in primary care. Therefore, we studied patient medical records from two dementia clinics and from the referring primary care centres...
  31. doi request reprint Pain treatment in elderly persons with and without dementia: a population-based study of institutionalized and home-dwelling elderly
    Ylva Haasum
    Aging Research Center, Department of Neurobiology, Care Sciences and Society NVS, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Drugs Aging 28:283-93. 2011
    ..Several previous studies have reported an undertreatment of pain in elderly persons with dementia. It has also been suggested that persons with dementia may be at risk for inappropriate treatment of pain with psychotropics...
  32. doi request reprint Net costs of dementia in Sweden - an incidence based 10 year simulation study
    Anders Sköldunger
    NVS, Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Int J Geriatr Psychiatry 27:1112-7. 2012
    ..Therefore, modeling approaches are frequently used. The purpose of this study was to describe the costs of an incident dementia cohort with progression modeling...
  33. ncbi request reprint Anti-dementia drugs and co-medication among patients with Alzheimer's disease : investigating real-world drug use in clinical practice using the Swedish Dementia Quality Registry (SveDem)
    Seyed Mohammad Fereshtehnejad
    Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences, and Society NVS, Karolinska Institutet, Novum 5th floor, 14186, Stockholm, Sweden
    Drugs Aging 31:215-24. 2014
    ..There is a substantial risk of drug-interactions, adverse events, and inappropriate drug use (IDU) among frail Alzheimer's disease (AD) patients; however, there are few studies about co-medication and IDU in clinical settings...
  34. pmc A brief conceptual tutorial of multilevel analysis in social epidemiology: using measures of clustering in multilevel logistic regression to investigate contextual phenomena
    Juan Merlo
    Department of Clinical Sciences Community Medicine, Malmo University Hospital, Faculty of Medicine, Lund University, S 205 02 Malmo, Sweden
    J Epidemiol Community Health 60:290-7. 2006
    ..The aim of this study was to present measures of variation appropriate for the logistic case in a didactic rather than a mathematical way. Design and..