S G O Johansson

Summary

Affiliation: Karolinska Hospital
Country: Sweden

Publications

  1. ncbi Omalizumab and the immune system: an overview of preclinical and clinical data
    S G O Johansson
    Department of Clinical Immunology, Karolinska Hospital, Stockholm, Sweden
    Ann Allergy Asthma Immunol 89:132-8. 2002
  2. ncbi New diagnostic classification of allergic skin disorders
    S G O Johansson
    Department of Clinical Immunology, Karolinska Hospital, Stockholm, Sweden
    Curr Opin Allergy Clin Immunol 2:403-6. 2002
  3. ncbi Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003
    S G O Johansson
    Department of Medicine, Unit of Clinical Immunology and Allergy, Karolinska University Hospital, L2 04, S 171 76 Stockholm, Sweden
    J Allergy Clin Immunol 113:832-6. 2004
  4. doi The size of the disease relevant IgE antibody fraction in relation to 'total-IgE' predicts the efficacy of anti-IgE (Xolair) treatment
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 64:1472-7. 2009
  5. doi After 6 years with Xolair; a 3-year withdrawal follow-up
    Anna Nopp
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 65:56-60. 2010
  6. doi National pholcodine consumption and prevalence of IgE-sensitization: a multicentre study
    S G O Johansson
    Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden
    Allergy 65:498-502. 2010
  7. ncbi CD-sens and clinical changes during withdrawal of Xolair after 6 years of treatment
    A Nopp
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 62:1175-81. 2007
  8. ncbi Cat IgA, representative of new carbohydrate cross-reactive allergens
    Justus Adedoyin
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institutet, University Hospital, Stockholm, Sweden
    J Allergy Clin Immunol 119:640-5. 2007
  9. ncbi High prevalence of IgE antibodies among blood donors in Sweden and Norway
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institutet, Stockholm, Sweden
    Allergy 60:1312-5. 2005
  10. doi Xolair is effective in allergics with a low serum IgE level
    J Ankerst
    Department of Medicine, Clinical Sciences, Lund, Sweden
    Int Arch Allergy Immunol 152:71-4. 2010

Detail Information

Publications43

  1. ncbi Omalizumab and the immune system: an overview of preclinical and clinical data
    S G O Johansson
    Department of Clinical Immunology, Karolinska Hospital, Stockholm, Sweden
    Ann Allergy Asthma Immunol 89:132-8. 2002
    ..This review discusses the role of immunoglobulin (Ig)E in allergic disease, inhibition of IgE with omalizumab, and the consequences of IgE inhibition (both clinically and in terms of the effect on the immune system)...
  2. ncbi New diagnostic classification of allergic skin disorders
    S G O Johansson
    Department of Clinical Immunology, Karolinska Hospital, Stockholm, Sweden
    Curr Opin Allergy Clin Immunol 2:403-6. 2002
    ..To highlight the importance of one common nomenclature for allergic skin disorders...
  3. ncbi Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003
    S G O Johansson
    Department of Medicine, Unit of Clinical Immunology and Allergy, Karolinska University Hospital, L2 04, S 171 76 Stockholm, Sweden
    J Allergy Clin Immunol 113:832-6. 2004
    ..It is assumed that as knowledge about basic causes and mechanisms improves, the nomenclature will need further review...
  4. doi The size of the disease relevant IgE antibody fraction in relation to 'total-IgE' predicts the efficacy of anti-IgE (Xolair) treatment
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 64:1472-7. 2009
    ..e. the percentage of IgE antibody of total IgE, was evaluated in cat allergic patients treated with the recommended doses of Xolair. Results were measured as changes in basophil allergen threshold sensitivity (CD-sens)...
  5. doi After 6 years with Xolair; a 3-year withdrawal follow-up
    Anna Nopp
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 65:56-60. 2010
    ..This study reports the clinical and immunological state of patients 3 years after a 6-year period of Xolair treatment for severe allergic asthma...
  6. doi National pholcodine consumption and prevalence of IgE-sensitization: a multicentre study
    S G O Johansson
    Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden
    Allergy 65:498-502. 2010
    ..As a consequence the risk of anaphylaxis to neuromuscular blocking agents (NMBA) will be increased...
  7. ncbi CD-sens and clinical changes during withdrawal of Xolair after 6 years of treatment
    A Nopp
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 62:1175-81. 2007
    ..e. <12 months. After withdrawal, the clinical symptoms tend to return. A group of patients who stopped treatment after approx. 6 years allowed studies of the long-term effects of Xolair...
  8. ncbi Cat IgA, representative of new carbohydrate cross-reactive allergens
    Justus Adedoyin
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institutet, University Hospital, Stockholm, Sweden
    J Allergy Clin Immunol 119:640-5. 2007
    ..Allergens from cat are among the most potent elicitors of allergic disease. Four cat allergens have been identified; however, evidence indicates the existence of additional allergens...
  9. ncbi High prevalence of IgE antibodies among blood donors in Sweden and Norway
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institutet, Stockholm, Sweden
    Allergy 60:1312-5. 2005
    ..Reactions after a blood transfusion could be allergic because of passive transfer of immunoglobulin E (IgE) antibodies from allergic donors...
  10. doi Xolair is effective in allergics with a low serum IgE level
    J Ankerst
    Department of Medicine, Clinical Sciences, Lund, Sweden
    Int Arch Allergy Immunol 152:71-4. 2010
    ..Two atopic patients suffering from severe allergy difficult to handle by conventional medication were given Xolair despite an IgE level <30 kU/l...
  11. ncbi Simultaneous exposure of several allergens has an additive effect on multisensitized basophils
    A Nopp
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 61:1366-8. 2006
    ..In order to study if such an effect could be detected on the inflammatory, cellular level, multisensitized basophils were challenged with various dose combinations of two relevant allergens...
  12. ncbi Basophil allergen threshold sensitivity: a useful approach to anti-IgE treatment efficacy evaluation
    A Nopp
    Clinical Immunology and Allergy Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden
    Allergy 61:298-302. 2006
    ..The objective of this study was to investigate how basophil allergen sensitivity can be applied in the monitoring of anti-immunoglobulin E (IgE) treatment...
  13. doi CD-sens can be a reliable and easy-to-use complement in the diagnosis of allergic rhinitis
    A Nopp
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Int Arch Allergy Immunol 161:87-90. 2013
    ..A reproducible standard for a graded allergen response in allergic rhinitis is lacking. The aim was to evaluate basophil allergen threshold sensitivity, CD-sens, as a diagnostic complement to nasal allergen challenge...
  14. doi CD-sens: a biological measure of immunological changes stimulated by ASIT
    A Nopp
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 64:811-4. 2009
    ..Basophil allergen threshold sensitivity, CD-sens, which is a valuable complement to resource-demanding clinical challenge tests, was used to monitor the initiation of ASIT induced allergen 'blocking activity'...
  15. ncbi IgE-mediated anaphylactic reactions to neuromuscular blocking agents: can they be prevented?
    E Florvaag
    Department of Clinical Immunology, Karolinska University Hospital, Solna, L2 04, S 171 76, Stockholm, Sweden
    Curr Allergy Asthma Rep 8:375-6. 2008
  16. ncbi The importance of IgE antibody levels in anti-IgE treatment
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 61:1216-9. 2006
    ..Dosages of anti-immunoglobulin (Ig)E in treatment of allergic asthma is based on total IgE body pool assuming that IgE antibodies responsible for the disease are evenly distributed among patients. This assumption was evaluated...
  17. doi Combining analyses of basophil allergen threshold sensitivity, CD-sens, and IgE antibodies to hydrolyzed wheat, ω-5 gliadin and timothy grass enhances the prediction of wheat challenge outcome
    N Nilsson
    Department of Women s and Children s Health, Karolinska Institutet, Stockholm, Sweden
    Int Arch Allergy Immunol 162:50-7. 2013
    ....
  18. doi Basophil allergen threshold sensitivity, CD-sens, is a measure of allergen sensitivity in asthma
    B Dahlen
    Department of Medicine, Division of Respiratory Medicine and Allergy Research, Karolinska University Hospital, Huddinge, Sweden
    Clin Exp Allergy 41:1091-7. 2011
    ..The SPT and IgE-antibody values do not directly predict if the allergy clinically contributes to the asthma. There is therefore a need for new objective tests that may indicate the clinical importance of an IgE-sensitisation...
  19. doi Anaphylaxis to Patent Blue V. II. A unique IgE-mediated reaction
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 65:124-9. 2010
    ..Anaphylactic reactions, allegedly IgE antibody mediated, have been reported. The aim of the study was to explore the immunological mechanism of anaphylaxis to PBV...
  20. ncbi The discovery of immunoglobulin E
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy Asthma Proc 27:S3-6. 2006
    ..The knowledge about IgE mediating allergy has greatly improved our understanding of allergic inflammation and diagnoses and treatment of allergic diseases...
  21. ncbi Interference in immunoassays by human IgM with specificity for the carbohydrate moiety of animal proteins
    Justus Adedoyin
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden
    J Immunol Methods 310:117-25. 2006
    ..The factor was further studied and shown to be human IgM. This IgM fits into the heterophile antibody classification and is directed against carbohydrates on animal immunoglobulins and on calf intestine alkaline phosphatase...
  22. ncbi Antineutrophil cytoplasmic antibodies induce decreased CD62L expression and enhanced metabolic activity in monocytes
    A Wikman
    Department of Medicine, Division of Clinical Immunology and Transfusion Medicine, Karolinska Hospital and Karolinska Institutet, Stockholm, Sweden
    Scand J Immunol 57:179-84. 2003
    ..These findings support the concept that the pathophysiological effect of ANCA is partly mediated through the action on crucial events in monocyte activation, such as CD62L downregulation and oxygen radical production...
  23. pmc Oral peanut challenge identifies an allergy but the peanut allergen threshold sensitivity is not reproducible
    Susanne Glaumann
    Department of Clinical Science and Education, Sodersjukhuset, Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e53465. 2013
    ..A basophil allergen threshold sensitivity test, CD-sens, has shown promising results as a diagnostic tool in food allergy...
  24. doi Pet shop workers: exposure, sensitization, and work-related symptoms
    A Renström
    National Institute of Environmental Medicine, Lung and Allergy Research, Karolinska Institutet, Stockholm, Sweden
    Allergy 66:1081-7. 2011
    ..Allergy to laboratory animals is a well-known occupational hazard. The aim was to investigate the frequency of allergic sensitization and respiratory symptoms among pet shop staff and to document their work environment...
  25. ncbi ImmunoCAP Specific IgE test: an objective tool for research and routine allergy diagnosis
    S G O Johansson
    Department of Medicine, Unit of Clinical Immunology and Allergy, Karolinska University Hospital, L2 04 SE 171 76 Stockholm, Sweden
    Expert Rev Mol Diagn 4:273-9. 2004
    ..It is a reliable diagnostic tool and particularly useful in primary care where the use of in vivo tests cannot be recommended if the personnel have insufficient opportunities to get the appropriate experience...
  26. doi The History of IgE: From discovery to 2010
    S G O Johansson
    Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Solna, L2 04, 171 76, Stockholm, Sweden
    Curr Allergy Asthma Rep 11:173-7. 2011
    ....
  27. ncbi Passive IgE-sensitization by blood transfusion
    S G O Johansson
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute, Stockholm, Sweden
    Allergy 60:1192-9. 2005
    ..To study the mechanisms of passive sensitization of patients receiving plasma containing IgE antibodies to a defined allergen...
  28. pmc The Pholcodine Case. Cough Medicines, IgE-Sensitization, and Anaphylaxis: A Devious Connection
    E Florvaag
    1Laboratory of Clinical Biochemistry and Section for Clinical Allergology, Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway 2Institute of Medicine, University of Bergen, Norway 3Clinical Immunology and Allergy Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden 4Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden
    World Allergy Organ J 5:73-8. 2012
    ....
  29. ncbi The story of IgND
    S G O Johansson
    Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden
    J Allergy Clin Immunol 115:644-8. 2005
  30. ncbi IgE-reactivity to seven Malassezia species
    A Zargari
    Ludwig Institute for Cancer Research, Stockholm Branch, Stockholm, Sweden
    Allergy 58:306-11. 2003
    ..In this study, we evaluated the presence of immunoglobulin E (IgE) antibodies to different Malassezia spp. in AEDS patients to allow optimization of the characterization of the IgE antibody profile of IgE-associated AEDS...
  31. ncbi Pholcodine exposure raises serum IgE in patients with previous anaphylaxis to neuromuscular blocking agents
    T Harboe
    Department of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway
    Allergy 62:1445-50. 2007
    ..The present study explores the effect of pholcodine exposure on IgE in a population with previously diagnosed IgE-mediated anaphylaxis towards NMBAs...
  32. ncbi [Revised terminology for allergies and related conditions]
    R Gerth van Wijk
    Erasmus Medisch Centrum, afd Allergologie, Dr Molewaterplein 40, 3015 GD Rotterdam
    Ned Tijdschr Geneeskd 146:2289-93. 2002
    ....
  33. ncbi [Revised, global nomenclature for allergy. Unambiguous terms create clarity and prevent misunderstandings]
    S G O Johansson
    Avdelningen för klinisk immunologi och transfusionsmedicin, Karolinska Universitetssjukhuset Solna
    Lakartidningen 103:379-83. 2006
  34. ncbi Pholcodine stimulates a dramatic increase of IgE in IgE-sensitized individuals. A pilot study
    E Florvaag
    Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway
    Allergy 61:49-55. 2006
    ....
  35. ncbi No consumption of IgE antibody in serum during allergic drug anaphylaxis
    A B Guttormsen
    Department of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway
    Allergy 62:1326-30. 2007
    ..As this is most unpractical, the changes in IgE antibody levels during anaphylaxis were studied to evaluate the possibility of using samples drawn at the time of the reaction...
  36. ncbi Scandinavian Clinical Practice Guidelines on the diagnosis, management and follow-up of anaphylaxis during anaesthesia
    M Kroigaard
    Danish Anaesthesia Allergy Centre, Department of Anaesthesia, Section 4231 Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen University Hospital, DK 2100 Copenhagen, Denmark
    Acta Anaesthesiol Scand 51:655-70. 2007
    ..Lastly, Appendix 2 provides an overview of the incidence, mechanisms and possibilities for follow-up for some common drug groups...
  37. ncbi [Latex caused two cases of anaphylactic shock during Cesarean section]
    Caroline Gillis-Haegerstrand
    Danderyds sjukhus, Stockholm
    Lakartidningen 104:1987-8. 2007
  38. ncbi IgE to Staphylococcus aureus enterotoxins in serum is related to severity of asthma
    Claus Bachert
    J Allergy Clin Immunol 111:1131-2. 2003
  39. ncbi Organization of secondary lymphoid tissue and local IgE formation to Staphylococcus aureus enterotoxins in nasal polyp tissue
    P Gevaert
    Upper Airways Research Laboratory, Department of Otorhinolaryngology, Ghent University, Ghent, Belgium
    Allergy 60:71-9. 2005
    ..We aimed to study the relationship between systemic and local IgE formation, nasal carriage of Staphylococcus aureus and nasal polyposis...
  40. ncbi World Allergy Organization guidelines for prevention of allergy and allergic asthma
    Innes Asher
    World Allergy Organization Project, 96 Vambrugh Park, Blackheath, London SE3 7AL, UK
    Int Arch Allergy Immunol 135:83-92. 2004
  41. ncbi How atopic is atopic dermatitis?
    Carsten Flohr
    Centre of Evidence Based Dermatology, University of Nottingham, United Kingdom
    J Allergy Clin Immunol 114:150-8. 2004
    ..The extent to which the phenotype of atopic dermatitis (AD) is truly atopic has been the subject of much debate...
  42. ncbi Qualitative and quantitative evaluation of bird-specific IgG antibodies
    Andreas L Lopata
    Division of Immunology, Old Main Building H 43, Groote Schuur Hospital, National Health Laboratory Services, University of Cape Town, 7925 Cape Town, South Africa
    Int Arch Allergy Immunol 134:173-8. 2004
    ..The aim of this study was to establish the distribution of bird-specific IgG antibodies in exposed and nonexposed individuals and compare a nonquantitative and quantitative method in evaluating raised levels of IgG antibodies...
  43. ncbi Prevalence of IgE antibodies to morphine. Relation to the high and low incidences of NMBA anaphylaxis in Norway and Sweden, respectively
    E Florvaag
    Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway
    Acta Anaesthesiol Scand 49:437-44. 2005
    ..The prevalence of IgE-sensitization to morphine (MOR) and suxamethonium (SUX) in comparable populations in Bergen, Norway, and Stockholm, Sweden, was studied and related to possible sensitizing agents...