Erik Ingelsson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study
    Elisabet Nerpin
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, SE 751 85, Uppsala, Sweden
    BMC Res Notes 5:537. 2012
  2. pmc Evidence of a causal relationship between adiponectin levels and insulin sensitivity: a Mendelian randomization study
    He Gao
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes 62:1338-44. 2013
  3. doi Effects of trans10cis12CLA-induced insulin resistance on retinol-binding protein 4 concentrations in abdominally obese men
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes Res Clin Pract 82:e23-4. 2008
  4. doi Associations of serum adiponectin with skeletal muscle morphology and insulin sensitivity
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    J Clin Endocrinol Metab 94:953-7. 2009
  5. pmc Circulating retinol-binding protein 4 and subclinical cardiovascular disease in the elderly
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes Care 32:733-5. 2009
  6. doi Relative importance and conjoint effects of obesity and physical inactivity for the development of insulin resistance
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur J Cardiovasc Prev Rehabil 16:28-33. 2009
  7. doi Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Atherosclerosis 206:239-44. 2009
  8. pmc Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes 59:1266-75. 2010
  9. doi Multilocus genetic risk scores for coronary heart disease prediction
    Andrea Ganna
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Arterioscler Thromb Vasc Biol 33:2267-72. 2013
  10. doi Urinary kidney injury molecule 1 and incidence of heart failure in elderly men
    Axel C Carlsson
    Centre for Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden
    Eur J Heart Fail 15:441-6. 2013

Detail Information

Publications35

  1. pmc Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study
    Elisabet Nerpin
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, SE 751 85, Uppsala, Sweden
    BMC Res Notes 5:537. 2012
    ....
  2. pmc Evidence of a causal relationship between adiponectin levels and insulin sensitivity: a Mendelian randomization study
    He Gao
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes 62:1338-44. 2013
    ..The observed association between higher adiponectin levels and increased insulin sensitivity is likely to represent a causal relationship partly mediated by reduced adiposity...
  3. doi Effects of trans10cis12CLA-induced insulin resistance on retinol-binding protein 4 concentrations in abdominally obese men
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes Res Clin Pract 82:e23-4. 2008
    ..Further, there were no associations between CLA-induced insulin resistance and changes in RBP4...
  4. doi Associations of serum adiponectin with skeletal muscle morphology and insulin sensitivity
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    J Clin Endocrinol Metab 94:953-7. 2009
    ..Skeletal muscle morphology and function are strongly associated with insulin sensitivity...
  5. pmc Circulating retinol-binding protein 4 and subclinical cardiovascular disease in the elderly
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes Care 32:733-5. 2009
    ..We evaluated associations of serum retinol-binding protein 4 (RBP4) with subclinical cardiovascular disease (CVD)...
  6. doi Relative importance and conjoint effects of obesity and physical inactivity for the development of insulin resistance
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur J Cardiovasc Prev Rehabil 16:28-33. 2009
    ..Obesity and physical inactivity are related to the development of insulin resistance, but their relative importance and conjoint effects are unclear...
  7. doi Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Atherosclerosis 206:239-44. 2009
    ..Our aim was to examine relations of serum retinol-binding protein 4 (RBP4) to cardiovascular risk factors, and prevalent metabolic syndrome (MetS) and cardiovascular disease (CVD) in a large community-based sample of elderly...
  8. pmc Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes 59:1266-75. 2010
    ..Our findings emphasize the importance of detailed physiological characterization of such loci for improved understanding of pathways associated with alterations in glucose homeostasis and eventually type 2 diabetes...
  9. doi Multilocus genetic risk scores for coronary heart disease prediction
    Andrea Ganna
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Arterioscler Thromb Vasc Biol 33:2267-72. 2013
    ..We aimed to compare several multilocus genetic risk score (MGRS) in terms of association with CHD and to evaluate clinical use...
  10. doi Urinary kidney injury molecule 1 and incidence of heart failure in elderly men
    Axel C Carlsson
    Centre for Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden
    Eur J Heart Fail 15:441-6. 2013
    ..The objective of this study was to investigate whether urinary kidney injury molecule (KIM)-1, a specific marker of tubular damage, predisposes to an increased heart failure risk...
  11. doi Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?
    Andrea Ganna
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Hum Genet 132:553-61. 2013
    ..Our findings are compatible with the view of mortality as a complex and highly polygenetic trait, not easily explainable by common genetic variants related to diseases and physiological traits...
  12. doi Relations of circulating vitamin D concentrations with left ventricular geometry and function
    Tove Fall
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Eur J Heart Fail 14:985-91. 2012
    ..Hence, we examined associations of circulating vitamin D concentrations and left ventricular (LV) geometry and function by echocardiography at baseline and after 5 years in a community-based study...
  13. doi Associations of circulating adiponectin with measures of vascular function and morphology
    Stefan Gustafsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    J Clin Endocrinol Metab 95:2927-34. 2010
    ....
  14. doi Adiponectin and cardiac geometry and function in elderly: results from two community-based cohort studies
    Stefan Gustafsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, SE 171 77 Stockholm, Sweden
    Eur J Endocrinol 162:543-50. 2010
    ..Our objective was to investigate such associations in two large community-based studies of elderly...
  15. doi Conjoint effects of serum calcium and phosphate on risk of total, cardiovascular, and noncardiovascular mortality in the community
    Tobias E Larsson
    Department of Nephrology, Karolinska University Hospital, Stockholm, Sweden
    Arterioscler Thromb Vasc Biol 30:333-9. 2010
    ..Hyperphosphatemia is a cardiovascular risk factor in patients with chronic kidney disease. Relations of circulating calcium (Ca) and phosphorus (Pi) to long-term mortality risk in the community require further investigation...
  16. doi Oxidative stress and inflammatory markers in relation to circulating levels of adiponectin
    Stefan Gustafsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Obesity (Silver Spring) 21:1467-73. 2013
    ..Our objective was to investigate the relative importance of oxidative stress and inflammatory markers, representing different pathways in relation to adiponectin...
  17. pmc Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
    Rona J Strawbridge
    Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Diabetes 60:2624-34. 2011
    ..Studies of the insulin processing pathway could provide new insights about T2D pathophysiology...
  18. doi Clinical depression, antidepressant use and risk of future cardiovascular disease
    Iffat Rahman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 17177, Stockholm, Sweden
    Eur J Epidemiol 28:589-95. 2013
    ..The association with clinical depression is more marked in relation to stroke and disappears in relation to development of coronary heart disease. ..
  19. doi A genome-wide assessment of variability in human serum metabolism
    Mun Gwan Hong
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Hum Mutat 34:515-24. 2013
    ..mQTL SNPs and mQTL-harboring genes were over-represented across GWASs conducted to date, suggesting that these data may have utility in tracing the molecular basis of some complex disease associations...
  20. doi FTO genetic variants and risk of obesity and type 2 diabetes: A meta-analysis of 28,394 Indians
    Senthil K Vasan
    Department of Molecular Medicine and Surgery Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Stockholm, Sweden Department of Endocrinology Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India
    Obesity (Silver Spring) 22:964-70. 2014
    ..To investigate the magnitude of association of FTO variants with obesity, type 2 diabetes (T2DM), and related traits among Asian Indians...
  21. pmc Genetic variants from lipid-related pathways and risk for incident myocardial infarction
    Ci Song
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e60454. 2013
    ..Circulating lipids levels, as well as several familial lipid metabolism disorders, are strongly associated with initiation and progression of atherosclerosis and incidence of myocardial infarction (MI)...
  22. doi Associations of variants in FTO and near MC4R with obesity traits in South Asian Indians
    Senthil K Vasan
    Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    Obesity (Silver Spring) 20:2268-77. 2012
    ..The detection of these associations in Indians is challenging because conventional anthropometric obesity measures work poorly in the Indian "thin-fat" phenotype...
  23. doi The Swedish Twin Registry: establishment of a biobank and other recent developments
    Patrik K E Magnusson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 16:317-29. 2013
    ..Coverage by year of birth, zygosity determination, ethnic heterogeneity, and influences of in vitro fertilization are also described...
  24. doi Familial effects on ischemic stroke: the role of sibling kinship, sex, and age of onset
    Katherine Kasiman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Circ Cardiovasc Genet 5:226-33. 2012
    ..This study aimed to characterize these familial effects in a nationwide population-based study by taking into account sibling relations, sex of siblings, and age of onset, with respect to ischemic stroke incidence...
  25. pmc Risk prediction measures for case-cohort and nested case-control designs: an application to cardiovascular disease
    Andrea Ganna
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 175:715-24. 2012
    ....
  26. doi Birth characteristics and subsequent risks of maternal cardiovascular disease: effects of gestational age and fetal growth
    Anna Karin Edstedt Bonamy
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    Circulation 124:2839-46. 2011
    ..Prior studies showing an inverse relationship between low birth weight in offspring and maternal risks of cardiovascular diseases (CVD) are limited by lack of information on gestational age and/or insufficient adjustment for confounders...
  27. pmc Utilizing twins as controls for non-twin case-materials in genome wide association studies
    Andrea Ganna
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e83101. 2013
    ..In conclusion, twins and singletons can be used in genetic studies together with general population samples without introducing large bias. Further research is needed to explore genetic variances associated with DZ twinning. ..
  28. doi LifeGene--a large prospective population-based study of global relevance
    Catarina Almqvist
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    Eur J Epidemiol 26:67-77. 2011
    ..Questions and sampling schemes will be tailored to the participants' age and life events. The target of LifeGene is to enroll 500,000 Swedes and follow them longitudinally for at least 20 years...
  29. doi Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Allergy Clin Immunol 129:702-707.e2. 2012
    ..The leukotriene pathway has been associated with an increased cardiovascular risk. However, the effects of the antileukotriene treatment used in asthmatic patients on cardiovascular outcomes have remained largely unexplored...
  30. doi Hysterectomy and risk of cardiovascular disease: a population-based cohort study
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    Eur Heart J 32:745-50. 2011
    ..In this population-based cohort study, we studied the effects of hysterectomy, with or without oopherectomy, on the risk of later life CVD...
  31. pmc The role of adiposity in cardiometabolic traits: a mendelian randomization analysis
    Tove Fall
    Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    PLoS Med 10:e1001474. 2013
    ..Whilst the causal relationship is clear for some of these traits, for others it is not. We aimed to determine whether adiposity is causally related to various cardiometabolic traits using the Mendelian randomization approach...
  32. pmc Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease
    Mun Gwan Hong
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Hum Mutat 33:521-9. 2012
    ....
  33. pmc The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    BMC Cardiovasc Disord 8:37. 2008
    ....
  34. doi Valvular osteoclasts in calcification and aortic valve stenosis severity
    Edit Nagy
    Department of Medicine, Karolinska Institutet, Stockholm, Sweden Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden Electronic address
    Int J Cardiol 168:2264-71. 2013
    ....
  35. doi Genome-wide association studies of obesity and metabolic syndrome
    Tove Fall
    Dept of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden
    Mol Cell Endocrinol 382:740-57. 2014
    ..This systematic review of obesity GWAS will summarize genome-wide significant findings for obesity and metabolic syndrome and briefly give a few suggestions of what is to be expected in the next few years. ..