- 2R and remodeling of vertebrate signal transduction engineLukasz Huminiecki
Ludwig Institute for Cancer Research, Uppsala University, Box 595, SE 751 24 Uppsala, Sweden
BMC Biol 8:146. 2010..Two rounds of WGD (2R-WGD) occurred at the base of vertebrates, giving rise to an enormous wave of genetic novelty, but a systematic analysis of functional consequences of this event has not yet been performed...
- Emergence, development and diversification of the TGF-beta signalling pathway within the animal kingdomLukasz Huminiecki
Ludwig Institute for Cancer Research, Uppsala University, Uppsala, Sweden
BMC Evol Biol 9:28. 2009..Herein, we focus on the diversification of the transforming growth factor-beta (TGF-beta) pathway -- one of the fundamental and versatile metazoan signal transduction engines...