Anders Helander

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. doi request reprint Asymptomatic phosphomannose isomerase deficiency (MPI-CDG) initially mistaken for excessive alcohol consumption
    Anders Helander
    Karolinska Institutet, Department of Laboratory Medicine, Stockholm, Sweden Karolinska University Laboratory, Clinical Chemistry, Stockholm, Sweden Electronic address
    Clin Chim Acta 431:15-8. 2014
  2. ncbi request reprint Dolichol kinase deficiency (DOLK-CDG) with a purely neurological presentation caused by a novel mutation
    Anders Helander
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden Karolinska University Laboratory, Stockholm, Sweden Electronic address
    Mol Genet Metab 110:342-4. 2013
  3. doi request reprint Identification of novel psychoactive drug use in Sweden based on laboratory analysis--initial experiences from the STRIDA project
    Anders Helander
    Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Laboratory, Stockholm, Sweden
    Scand J Clin Lab Invest 73:400-6. 2013
  4. doi request reprint Effect of transferrin glycation on the use of carbohydrate-deficient transferrin as an alcohol biomarker
    Anders Helander
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Alcohol Alcohol 48:478-82. 2013
  5. doi request reprint Monitoring of the alcohol biomarkers PEth, CDT and EtG/EtS in an outpatient treatment setting
    Anders Helander
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, C1 74, Clinical Chemistry, Karolinska University Laboratory Huddinge, SE 141 86 Stockholm, Sweden
    Alcohol Alcohol 47:552-7. 2012
  6. pmc Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants
    Inge Ringmets
    Department of Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia
    BMC Public Health 12:146. 2012
  7. doi request reprint Toward standardization of carbohydrate-deficient transferrin (CDT) measurements: II. Performance of a laboratory network running the HPLC candidate reference measurement procedure and evaluation of a candidate reference material
    Anders Helander
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin Chem Lab Med 48:1585-92. 2010
  8. doi request reprint Unreliable alcohol testing in a shipping safety programme
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Forensic Sci Int 189:e45-7. 2009
  9. doi request reprint Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Clin Chem 55:1395-405. 2009
  10. ncbi request reprint Postcollection synthesis of ethyl glucuronide by bacteria in urine may cause false identification of alcohol consumption
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    Clin Chem 53:1855-7. 2007

Collaborators

Detail Information

Publications64

  1. doi request reprint Asymptomatic phosphomannose isomerase deficiency (MPI-CDG) initially mistaken for excessive alcohol consumption
    Anders Helander
    Karolinska Institutet, Department of Laboratory Medicine, Stockholm, Sweden Karolinska University Laboratory, Clinical Chemistry, Stockholm, Sweden Electronic address
    Clin Chim Acta 431:15-8. 2014
    ..Two of three siblings were not affected, whereas one brother was also homozygous for c.656G>A and had a highly elevated CDT and no clinical symptoms...
  2. ncbi request reprint Dolichol kinase deficiency (DOLK-CDG) with a purely neurological presentation caused by a novel mutation
    Anders Helander
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden Karolinska University Laboratory, Stockholm, Sweden Electronic address
    Mol Genet Metab 110:342-4. 2013
    ..2 T > C) in both siblings. In conclusion, two siblings were demonstrated to suffer from DOLK-CDG (MIM 610768) and to be homozygous for a new mutation. They presented with West syndrome and so far show a purely neurological phenotype...
  3. doi request reprint Identification of novel psychoactive drug use in Sweden based on laboratory analysis--initial experiences from the STRIDA project
    Anders Helander
    Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Laboratory, Stockholm, Sweden
    Scand J Clin Lab Invest 73:400-6. 2013
    ....
  4. doi request reprint Effect of transferrin glycation on the use of carbohydrate-deficient transferrin as an alcohol biomarker
    Anders Helander
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Alcohol Alcohol 48:478-82. 2013
    ..The present work examined whether non-enzymatic reaction of transferrin with glucose (glycation) might interfere with the use of CDT as an alcohol biomarker...
  5. doi request reprint Monitoring of the alcohol biomarkers PEth, CDT and EtG/EtS in an outpatient treatment setting
    Anders Helander
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, C1 74, Clinical Chemistry, Karolinska University Laboratory Huddinge, SE 141 86 Stockholm, Sweden
    Alcohol Alcohol 47:552-7. 2012
    ..Urinary ethyl glucuronide (EtG) and ethyl sulfate (EtS), and clinical assessment, were used as complementary estimates of relapse to drinking...
  6. pmc Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants
    Inge Ringmets
    Department of Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia
    BMC Public Health 12:146. 2012
    ..We describe the design and initial findings of a study aimed at investigating the association of alcohol with mortality in a large series of forensic autopsies of working-age men in Estonia...
  7. doi request reprint Toward standardization of carbohydrate-deficient transferrin (CDT) measurements: II. Performance of a laboratory network running the HPLC candidate reference measurement procedure and evaluation of a candidate reference material
    Anders Helander
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin Chem Lab Med 48:1585-92. 2010
    ..9% to 5.5%. The logistics for distribution of reference materials and review of results were found to be functional, indicating that a full reference system for CDT may soon be available...
  8. doi request reprint Unreliable alcohol testing in a shipping safety programme
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Forensic Sci Int 189:e45-7. 2009
    ..This and other questionable cases prompted investigation of the suitability of urine alcohol testing for the intended application...
  9. doi request reprint Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Clin Chem 55:1395-405. 2009
    ..We developed an electrospray ionization (ESI) LC-MS method for qualitative and quantitative measurement of different PEth species in human blood...
  10. ncbi request reprint Postcollection synthesis of ethyl glucuronide by bacteria in urine may cause false identification of alcohol consumption
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    Clin Chem 53:1855-7. 2007
    ..This study examined if bacterial pathogens in urine may enable postsampling synthesis of EtG and ethyl sulfate (EtS) from ethanol, leading to clinical false-positive results...
  11. ncbi request reprint [Positive alcohol breath test following methadone solution]
    Anders Helander
    Beroendecentrum, Stockholms läns landsting
    Lakartidningen 104:2217-8; discussion 2218. 2007
  12. doi request reprint Comparison of analytical approaches for liquid chromatography/mass spectrometry determination of the alcohol biomarker ethyl glucuronide in urine
    Anders Helander
    Karolinska Institutet, Department of Laboratory Medicine, Stockholm, Sweden
    Rapid Commun Mass Spectrom 24:1737-43. 2010
    ..These results indicate that the likelihood of different analytical methods to provide reliable analytical results depends on the reporting limit applied...
  13. ncbi request reprint Determination of carbohydrate-deficient transferrin in human serum using the Bio-Rad %CDT by HPLC test
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
    Clin Chim Acta 371:187-90. 2006
    ..This study evaluated the performance of a new commercial method for CDT, the Bio-Rad %CDT by HPLC test, that measures relative amounts of separate transferrin glycoforms in proportion to total transferrin...
  14. doi request reprint Detection times for urinary ethyl glucuronide and ethyl sulfate in heavy drinkers during alcohol detoxification
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Alcohol Alcohol 44:55-61. 2009
    ..This study determined the detection times for EtG and EtS in alcoholic patients undergoing alcohol detoxification...
  15. ncbi request reprint Biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct UPLC-tandem MS and ELISA methods
    Olof Beck
    Department of Medicine, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden
    Alcohol Alcohol 42:321-5. 2007
    ..This study compared two new methods for direct determination of 5-hydroxytryptophol glucuronide (GTOL) in urine, a biomarker for detection of recent alcohol consumption...
  16. doi request reprint Urinary ethyl glucuronide and ethyl sulfate testing for recent drinking in alcohol-dependent outpatients treated with acamprosate or placebo
    Helen Dahl
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Alcohol Alcohol 46:553-7. 2011
    ..This study compared urinary EtG and EtS measurement with self-reports for detection of prior drinking in alcohol-dependent outpatients treated with the anti-craving medication acamprosate or placebo...
  17. doi request reprint Urinary ethyl glucuronide and ethyl sulfate testing for detection of recent drinking in an outpatient treatment program for alcohol and drug dependence
    Helen Dahl
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Alcohol Alcohol 46:278-82. 2011
    ..This study determined the information about recent alcohol consumption obtained when urinary ethyl glucuronide (EtG) and ethyl sulfate (EtS) were introduced as a routine test in outpatient treatment programs for alcohol and drug dependence...
  18. ncbi request reprint Bioanalytical investigation of asarone in connection with Acorus calamus oil intoxications
    Kristian Björnstad
    Alcohol Laboratory, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Anal Toxicol 33:604-9. 2009
    ..calamus. The main clinical symptom reported by the patients was prolonged vomiting that sometimes lasted more than 15 h...
  19. doi request reprint Screening and brief intervention for risky alcohol consumption in the workplace: results of a 1-year randomized controlled study
    Ulric Hermansson
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Alcohol Alcohol 45:252-7. 2010
    ..To assess the effectiveness of brief alcohol intervention on hazardous and harmful drinking in the 12-month period after a voluntary alcohol screening...
  20. ncbi request reprint Ethyl sulfate: a metabolite of ethanol in humans and a potential biomarker of acute alcohol intake
    Anders Helander
    Department of Clinical Neuroscience and University Hospital, Stockholm, Sweden
    J Anal Toxicol 29:270-4. 2005
    ..It is also indicated that the concurrent determination of EtS and EtG will improve sensitivity, when being used as biomarkers of recent drinking...
  21. ncbi request reprint Comparison of urinary excretion characteristics of ethanol and ethyl glucuronide
    Helen Dahl
    Department of Clinical Neuroscience, Karolinska Institute and Hospital, Stockholm, Sweden
    J Anal Toxicol 26:201-4. 2002
    ..Moreover, it was possible to lower the concentration of EtG by drinking large amounts of water prior to voiding, whereas this strategy did not influence the EtG/creatinine ratio or the concentration of ethanol...
  22. ncbi request reprint Urinary tract infection: a risk factor for false-negative urinary ethyl glucuronide but not ethyl sulfate in the detection of recent alcohol consumption
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet and University Hospital, Stockholm, Sweden
    Clin Chem 51:1728-30. 2005
  23. ncbi request reprint Screening for high-risk and elevated alcohol consumption in day and shift workers by use of the AUDIT and CDT
    Ulric Hermansson
    Karolinska Institutet, Department of Clinical Neuroscience, Center for Dependency Disorders, Karolinska Hospital, Stockholm, Sweden
    Occup Med (Lond) 53:518-26. 2003
    ..However, no studies have evaluated the Alcohol Use Disorders Identification Test (AUDIT) or the alcohol biomarker carbohydrate-deficient transferrin (CDT) in serum for this purpose...
  24. doi request reprint Bioanalytical and clinical evaluation of 103 suspected cases of intoxications with psychoactive plant materials
    Kristian Björnstad
    Department of Clinical Neuroscience, Alcohol Laboratory, Karolinska Institutet, Stockholm, Sweden
    Clin Toxicol (Phila) 47:566-72. 2009
    ..This study involved bioanalytical and clinical examinations of intoxication cases suspected to be linked to such plant materials...
  25. ncbi request reprint Improved HPLC method for carbohydrate-deficient transferrin in serum
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, SE 171 76 Stockholm, Sweden
    Clin Chem 49:1881-90. 2003
    ..We describe an improved HPLC method for transferrin glycoforms...
  26. ncbi request reprint Comparison of HPLC and capillary electrophoresis for confirmatory testing of the alcohol misuse marker carbohydrate-deficient transferrin
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet and University Hospital, Stockholm, Sweden
    Clin Chem 51:1528-31. 2005
  27. doi request reprint A multi-component LC-MS/MS method for detection of ten plant-derived psychoactive substances in urine
    Kristian Björnstad
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    J Chromatogr B Analyt Technol Biomed Life Sci 877:1162-8. 2009
    ..The multi-component method proved to be useful for investigation of authentic cases of intoxication with plant-derived psychoactive drugs and was indicated to cover the clinically relevant concentration ranges...
  28. doi request reprint Changes in transferrin glycosylation during pregnancy may lead to false-positive carbohydrate-deficient transferrin (CDT) results in testing for riskful alcohol consumption
    Naama Kenan
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin Chim Acta 412:129-33. 2011
    ..This study examined the transferrin glycosylation profile and the risk for false-positive CDT results during pregnancy...
  29. ncbi request reprint HPLC evaluation of clinical and pharmacological factors reported to cause false-positive carbohydrate-deficient transferrin (CDT) levels
    Jonas P Bergström
    Department of Clinical Neuroscience, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
    Clin Chim Acta 389:164-6. 2008
    ..This HPLC study evaluated some clinical conditions and medications previously suggested to interfere with and cause non-alcohol related elevations of CDT...
  30. ncbi request reprint Influence of alcohol use, ethnicity, age, gender, BMI and smoking on the serum transferrin glycoform pattern: implications for use of carbohydrate-deficient transferrin (CDT) as alcohol biomarker
    Jonas P Bergström
    Department of Clinical Neuroscience, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
    Clin Chim Acta 388:59-67. 2008
    ....
  31. ncbi request reprint Direct quantification of ethyl glucuronide in clinical urine samples by liquid chromatography-mass spectrometry
    Nikolai Stephanson
    Department of Medicine, Division of Clinical Pharmacology, Alcohol Laboratory, Karolinska Institute and Hospital, Stockholm, Sweden
    Ther Drug Monit 24:645-51. 2002
    ....
  32. doi request reprint Clinical characteristics of carbohydrate-deficient transferrin (%disialotransferrin) measured by HPLC: sensitivity, specificity, gender effects, and relationship with other alcohol biomarkers
    Jonas P Bergström
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Alcohol Alcohol 43:436-41. 2008
    ....
  33. ncbi request reprint 5-hydroxytryptophol as a marker for recent alcohol intake
    Olof Beck
    Department of Medicine, Division of Clinical Pharmacology, Karolinska Hospital, Stockholm, Sweden
    Addiction 98:63-72. 2003
    ..To review the mechanism behind the alcohol-induced shift in serotonin metabolism, and the use of urinary 5-hydroxytryptophol (5-HTOL) as a biochemical marker of acute alcohol consumption...
  34. ncbi request reprint Development and clinical application of an LC-MS-MS method for mescaline in urine
    Kristian Björnstad
    Department of Clinical Neuroscience, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden
    J Anal Toxicol 32:227-31. 2008
    ..Among 462 urine samples collected from young people with alcohol or drug problems, 32% were positive for illicit drugs, but none for mescaline...
  35. ncbi request reprint Solid-phase extraction procedure for ethyl glucuronide in urine
    Yufang Zheng
    Department of Clinical Neuroscience, Karolinska Institutet and Alcohol Laboratory, Karolinska University Hospital, Stockholm, Sweden
    J Anal Toxicol 32:778-81. 2008
    ..The urinary EtG results with SPE followed by LC-MS were highly correlated (r(2) = 0.959) with those obtained using a sensitive and selective ultra-performance LC-tandem MS method...
  36. ncbi request reprint Testing for congenital disorders of glycosylation by HPLC measurement of serum transferrin glycoforms
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet and University Hospital, Stockholm, Sweden
    Clin Chem 50:954-8. 2004
  37. ncbi request reprint Mass spectrometric identification of ethyl sulfate as an ethanol metabolite in humans
    Anders Helander
    Karolinska Institutet and University Hospital, Department of Clinical Neuroscience, Stockholm, Sweden
    Clin Chem 50:936-7. 2004
  38. doi request reprint Method development for routine liquid chromatography-mass spectrometry measurement of the alcohol biomarker phosphatidylethanol (PEth) in blood
    Yufang Zheng
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin Chim Acta 412:1428-35. 2011
    ..Measurement of PEth in whole blood samples is employed as an alcohol biomarker. This work aimed to further develop an LC-MS method for PEth to make it practical for routine laboratory use...
  39. ncbi request reprint Laboratory tests for acute alcohol consumption: results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Alcohol Clin Exp Res 26:1070-7. 2002
    ..Comparison was made with self-reported drinking levels...
  40. ncbi request reprint [5-HTOL--a new biochemical alcohol marker with forensic applications]
    Anders Helander
    Beroendecentrum, Karolinska sjukhuset och Karolinska institutet, Stockholm
    Lakartidningen 99:3950-4. 2002
    ..Examples include suspected drunk drivers, rape victims, and medico-legal autopsies where forensic ethanol analysis is requested...
  41. doi request reprint Importance of HPLC confirmation of problematic carbohydrate-deficient transferrin (CDT) results from a multicapillary electrophoresis routine method
    Naama Kenan
    Alcohol Laboratory, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin Chim Acta 411:1945-50. 2010
    ....
  42. ncbi request reprint Multicentre validation study of instrument applications for %CDT, an immunoassay for quantification of carbohydrate-deficient transferrin in serum
    Anders Helander
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Alcohol Alcohol 37:209-12. 2002
    ..The data indicate that transferability of the %CDT assay is high, and that the instrument applications may be used interchangeably in routine quantification of %CDT...
  43. ncbi request reprint A comprehensive workplace intervention and its outcome with regard to lifestyle, health and sick leave: the AHA study
    Gunnar Bergström
    Section for Personal Injury Prevention, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Work 31:167-80. 2008
    ..This comprehensive workplace intervention programme appears to have had positive effects on smoking habits, HRQoL and sick leave...
  44. ncbi request reprint Urinary excretion patterns of 5-hydroxyindole-3-acetic acid and 5-hydroxytryptophol in various animal species: implications for studies on serotonin metabolism and turnover rate
    Margareta Some
    Department of Clinical Neuroscience, Alcohol Laboratory L7 03, Karolinska Institutet and Hospital, SE 171 76, Stockholm, Sweden
    Life Sci 71:2341-9. 2002
    ....
  45. ncbi request reprint The Alcohol Use Disorders Identification Test and carbohydrate-deficient transferrin in alcohol-related sickness absence
    Ulric Hermansson
    Karolinska Institute, Department of Clinical Neuroscience, Center for Dependency Disorders, Karolinska Hospital, Stockholm, Sweden
    Alcohol Clin Exp Res 26:28-35. 2002
    ..The purpose of this study was to examine the relationship between sick-days, 12 months before screening, and the AUDIT and CDT (CDTect kit). Serum gamma-glutamyltransferase also was used for comparison...
  46. ncbi request reprint Detectability of new psychoactive substances, 'legal highs', in CEDIA, EMIT, and KIMS immunochemical screening assays for drugs of abuse
    Olof Beck
    Department of Laboratory Medicine, Section of Clinical Pharmacology, Karolinska University Hospital, Sweden
    Drug Test Anal 6:492-9. 2014
    ..In both spiked and authentic urine samples, some new substances showed significant cross-reactivity and are thus detectable in the routine screening methods. Copyright © 2014 John Wiley & Sons, Ltd. ..
  47. ncbi request reprint CDT, GGT, and AST as markers of alcohol use: the WHO/ISBRA collaborative project
    Katherine M Conigrave
    Drug and Alcohol Department, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Sydney, Australia
    Alcohol Clin Exp Res 26:332-9. 2002
    ..The WHO/ISBRA Collaborative Study allows assessment and comparison of CDT, GGT, and aspartate aminotransferase (AST) as markers of drinking in a large, well-characterized, multicenter sample...
  48. ncbi request reprint Urinary ethyl glucuronide and 5-hydroxytryptophol levels during repeated ethanol ingestion in healthy human subjects
    Taisto Sarkola
    Department of Mental Health and Alcohol Research, National Public Health Institute, POB 33, Fin 00251 Helsinki, Finland
    Alcohol Alcohol 38:347-51. 2003
    ....
  49. ncbi request reprint Multicentre evaluation of a new assay for determination of carbohydrate-deficient transferrin
    Markus J Schwarz
    Psychiatrische Klinik der Ludwig Maximilian Universität, Munchen, Germany
    Alcohol Alcohol 38:270-5. 2003
    ..The analytical performance of the new Tina-quant % carbohydrate-deficient transferrin (%CDT) was assessed in a multicentre study on Roche/Hitachi analysers...
  50. doi request reprint HPLC and mass spectrometric characterization of a candidate reference material for the alcohol biomarker carbohydrate-deficient transferrin (CDT)
    Walter Oberrauch
    Bio Rad Laboratories GmbH, Munich, Germany
    Clin Chim Acta 395:142-5. 2008
    ..This study characterized a candidate reference material for CDT measurement derived from isolated human transferrin glycoforms...
  51. ncbi request reprint A pharmacokinetic study of ethyl glucuronide in blood and urine: applications to forensic toxicology
    Gudrun Høiseth
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Nydalen, Oslo, Norway
    Forensic Sci Int 172:119-24. 2007
    ..For this purpose, two subsequent increasing EtG values and a high ethanol-to-EtG ratio in blood would support information of recent drinking...
  52. ncbi request reprint Development and multicenter evaluation of the N latex CDT direct immunonephelometric assay for serum carbohydrate-deficient transferrin
    Joris R Delanghe
    Department of Clinical Chemistry, Ghent University Hospital, Ghent, Belgium
    Clin Chem 53:1115-21. 2007
    ..We describe the development and multicenter evaluation of N Latex CDT (Dade Behring), an automated, particle-enhanced, homogeneous immunonephelometric assay for directly determining CDT...
  53. ncbi request reprint Urinary ethyl glucuronide testing detects alcohol consumption in alcoholic liver disease patients awaiting liver transplantation
    Yesim Erim
    Department of Psychosomatic Medicine and Psychotherapy, University Hospital of Essen, Germany
    Liver Transpl 13:757-61. 2007
    ....
  54. ncbi request reprint Comparison of ethyl glucuronide in hair with phosphatidylethanol in whole blood as post-mortem markers of alcohol abuse
    Peter Bendroth
    Department of Forensic Medicine, SE 223 62 Lund, Sweden
    Forensic Sci Int 176:76-81. 2008
    ..However, an EtG level below the cutoff does not completely exclude previous alcohol abuse...
  55. ncbi request reprint [Final reply: the level of ethanol in Metadon DnE can surely be a problem]
    Anders Helander
    Lakartidningen 104:2450. 2007
  56. ncbi request reprint Evaluation of a new immunoassay for urinary ethyl glucuronide testing
    Michael Böttcher
    Arztpraxis für Medizinische Mikrobiologie und Labordiagnostik, Dessau, Germany
    Alcohol Alcohol 43:46-8. 2008
    ..This study evaluated a new enzyme immunoassay (DRI-EtG EIA, Microgenics Corp.) for determination of the EtG concentration in urine samples...
  57. doi request reprint Insufficient standardization of a direct carbohydrate-deficient transferrin immunoassay
    Anders Helander
    Clin Chem 54:1090-2. 2008
  58. doi request reprint Value of ethyl glucuronide in plasma as a biomarker for recent alcohol consumption in the emergency room
    Tim Neumann
    Department of Anesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Germany
    Alcohol Alcohol 43:431-5. 2008
    ....
  59. doi request reprint Comparison between the urinary alcohol markers EtG, EtS, and GTOL/5-HIAA in a controlled drinking experiment
    Gudrun Høiseth
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Pb 4404 Nydalen, N 0403 Oslo, Norway
    Alcohol Alcohol 43:187-91. 2008
    ..The aim of this controlled study was to compare the sensitivities and detection times of EtG, EtS, and GTOL/5-HIAA, after a single ingestion of ethanol...
  60. ncbi request reprint Determination of urinary 5-hydroxytryptophol glucuronide by liquid chromatography-mass spectrometry
    Nikolai Stephanson
    Department of Medicine, Division of Clinical Pharmacology, Karolinska Institute and University Hospital, SE 17176 Stockholm, Sweden
    J Chromatogr B Analyt Technol Biomed Life Sci 816:107-12. 2005
    ..99, n=70; mean 5-HTOL/GTOL ratio=1.10). This is the first direct assay for quantification of GTOL in urine. The method is suitable for routine application...
  61. ncbi request reprint Alcohol biomarker analysis: simultaneous determination of 5-hydroxytryptophol glucuronide and 5-hydroxyindoleacetic acid by direct injection of urine using ultra-performance liquid chromatography-tandem mass spectrometry
    Nikolai Stephanson
    Department of Medicine, Division of Clinical Pharmacology, Karolinska Institute and University Hospital, SE 171 76 Stockholm, Sweden
    J Mass Spectrom 42:940-9. 2007
    ..In conclusion, a fully validated and robust direct method for the routine measurement of urinary GTOL and 5-HIAA was developed...
  62. ncbi request reprint The effects of self-administered alcohol-induced 'hangover' in a naturalistic setting on psychomotor and cognitive performance and subjective state
    Frances Finnigan
    Department of Psychology, Glasgow Caledonian University, Glasgow, UK
    Addiction 100:1680-9. 2005
    ..To examine in as naturalistic a setting as possible whether having an alcohol-induced 'hangover' impairs psychomotor and cognitive performance...
  63. ncbi request reprint The relationship between whole-blood serotonin and subjective mood in apparently healthy postmenopausal women
    Maresa E Duffy
    The Northern Ireland Centre for Food and Health NICHE, University of Ulster, Coleraine, Northern Ireland, UK
    Biol Psychol 73:165-8. 2006
    ..03). No association was apparent for negative affect. These findings indicate that WB 5-HT and positive affect are related in postmenopausal women...
  64. ncbi request reprint Toward standardization of carbohydrate-deficient transferrin (CDT) measurements: I. Analyte definition and proposal of a candidate reference method
    Jan Olof Jeppsson
    Malmo University Hospital, Malmo, Sweden
    Clin Chem Lab Med 45:558-62. 2007
    ..In clinical use, CDT should be expressed in a relative amount (% CDT), to compensate for variations in the total transferrin concentration...