R Hast

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Long-term follow-up of 18 patients with myelodysplastic syndromes responding to recombinant erythropoietin treatment
    R Hast
    Division of Hematology, Department of Medicine, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Leuk Res 25:13-18. 2001
  2. ncbi request reprint Successful treatment with fludarabine in two cases of angioimmunoblastic lymphadenopathy with dysproteinemia
    R Hast
    Department of Medicine, Danderyd Hospital, Stockholm, Sweden
    Leuk Lymphoma 34:597-601. 1999
  3. ncbi request reprint Granulocyte-macrophage colony-stimulating factor to increase efficacy of mitoxantrone, etoposide and cytarabine in previously untreated elderly patients with acute myeloid leukaemia: a Swedish multicentre randomized trial
    C Lofgren
    Huddinge University Hospital, Stockholm, Sweden
    Br J Haematol 124:474-80. 2004
  4. ncbi request reprint Trisomy 12 and lymphoplasmacytoid lymphocytes in chronic leukemic B-cell disorders
    V Hjalmar
    Department of Medicine, Karolinska Institutet, Danderyd Hospital, Sweden
    Haematologica 83:602-9. 1998
  5. ncbi request reprint DNA image cytometry in MDS bone marrow smears
    S Widell
    Division of Cell and Molecular Analysis, Karolinska Hospital, Stockholm, Sweden
    Br J Haematol 105:960-5. 1999
  6. ncbi request reprint Atypical lymphocytes in B-cell chronic lymphocytic leukemia and trisomy 12 studied by conventional staining combined with fluorescence in situ hybridization
    V Hjalmar
    Division of Hematology, Department of Medicine, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Leuk Lymphoma 37:571-6. 2000
  7. ncbi request reprint Sequential fluorescence in situ hybridization analyses for trisomy 12 in chronic leukemic B-cell disorders
    V Hjalmar
    Division of Hematology, Karolinska Hospital, SE 171 76 Stockholm, Sweden
    Haematologica 86:174-80. 2001
  8. ncbi request reprint Imipenem/cilastatin monotherapy as salvage treatment in febrile neutropenic patients
    P Engervall
    Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    J Chemother 8:382-6. 1996
  9. ncbi request reprint Masked monosomy 7 in myelodysplastic syndromes is uncommon and of undetermined clinical significance
    K Jakovleva
    Department of Hematology, Division of Medicine, Karolinska Hospital, Karolinska Institutet, SE-171 76 Stockholm, Sweden
    Leuk Res 25:197-203. 2001
  10. ncbi request reprint No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease
    R Hast
    Division of Hematology, Department of Medicine, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Leukemia 17:1827-33. 2003

Detail Information

Publications12

  1. ncbi request reprint Long-term follow-up of 18 patients with myelodysplastic syndromes responding to recombinant erythropoietin treatment
    R Hast
    Division of Hematology, Department of Medicine, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Leuk Res 25:13-18. 2001
    ..Long-term responses were seen in about a third of the patients. Thus, it seems safe to reduce the EPO dose among responding patients. This approach may have advantages both from a medical and a socio-economic perspective...
  2. ncbi request reprint Successful treatment with fludarabine in two cases of angioimmunoblastic lymphadenopathy with dysproteinemia
    R Hast
    Department of Medicine, Danderyd Hospital, Stockholm, Sweden
    Leuk Lymphoma 34:597-601. 1999
    ..No severe infectious complications were noted. The use of purine analogues should be investigated further in AILD...
  3. ncbi request reprint Granulocyte-macrophage colony-stimulating factor to increase efficacy of mitoxantrone, etoposide and cytarabine in previously untreated elderly patients with acute myeloid leukaemia: a Swedish multicentre randomized trial
    C Lofgren
    Huddinge University Hospital, Stockholm, Sweden
    Br J Haematol 124:474-80. 2004
    ..GM-CSF prior to, and in combination with, induction treatment reduced the time to neutrophil recovery and the number of neutropenic septicaemia cases but did not improve the OS of AML in the elderly...
  4. ncbi request reprint Trisomy 12 and lymphoplasmacytoid lymphocytes in chronic leukemic B-cell disorders
    V Hjalmar
    Department of Medicine, Karolinska Institutet, Danderyd Hospital, Sweden
    Haematologica 83:602-9. 1998
    ....
  5. ncbi request reprint DNA image cytometry in MDS bone marrow smears
    S Widell
    Division of Cell and Molecular Analysis, Karolinska Hospital, Stockholm, Sweden
    Br J Haematol 105:960-5. 1999
    ..No difference between groups of MDS patients was found. DNA hypodiploidy is suggested to be a common feature in MDS without a relationship to cytogenetics...
  6. ncbi request reprint Atypical lymphocytes in B-cell chronic lymphocytic leukemia and trisomy 12 studied by conventional staining combined with fluorescence in situ hybridization
    V Hjalmar
    Division of Hematology, Department of Medicine, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Leuk Lymphoma 37:571-6. 2000
    ..This supports that both cell types have the same clonal origin and that different cell morphology cannot be explained alone by the acquisition of an additional chromosome 12...
  7. ncbi request reprint Sequential fluorescence in situ hybridization analyses for trisomy 12 in chronic leukemic B-cell disorders
    V Hjalmar
    Division of Hematology, Karolinska Hospital, SE 171 76 Stockholm, Sweden
    Haematologica 86:174-80. 2001
    ..The aberration is readily detected by fluorescence in situ hybridization (FISH). There are only a few reports in which FISH analyses have been used to study the expansion of the trisomy 12 clone over time...
  8. ncbi request reprint Imipenem/cilastatin monotherapy as salvage treatment in febrile neutropenic patients
    P Engervall
    Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    J Chemother 8:382-6. 1996
    ..In conclusion, the use of a treatment algorithm with I/C monotherapy as second-line treatment was safe and effective. Other antimicrobial agents, most often vancomycin and/or amphotericin B, had to be added in half of the patients...
  9. ncbi request reprint Masked monosomy 7 in myelodysplastic syndromes is uncommon and of undetermined clinical significance
    K Jakovleva
    Department of Hematology, Division of Medicine, Karolinska Hospital, Karolinska Institutet, SE-171 76 Stockholm, Sweden
    Leuk Res 25:197-203. 2001
    ..Thus, masked monosomy 7 is less common than has been suggested, and does not seem to carry the same prognostic weight as monosomy 7 diagnosed by metaphase cytogenetics...
  10. ncbi request reprint No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease
    R Hast
    Division of Hematology, Department of Medicine, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Leukemia 17:1827-33. 2003
    ..We present a clinically useful tool to predict response to chemotherapy and survival in elderly patients with transforming MDS, favoring patients with features of less proliferative disease...
  11. ncbi request reprint Oral versus intravenous melphalan and prednisone treatment in multiple myeloma stage II. A randomized study from the Myeloma Group of Central Sweden
    A Osterborg
    Department of Oncology, Karolinska Hopital, Stockholm, Sweden
    Acta Oncol 29:727-31. 1990
    ..Since intravenous administration of melphalan did not result in a substantial increase in response rate or survival, this study supports the use of oral melphalan/prednisone as first-line therapy for patients with multiple myeloma...
  12. ncbi request reprint DNA content of granulocytes, monocytes, and lymphocytes in the bone marrow smears of patients with myelodysplastic syndromes
    S Widell
    Cancer Center, Department of Oncology and Pathology, Karolinska Hospital, Karolinska Institute, Stockholm, Sweden
    Am J Hematol 67:112-8. 2001
    ..Clonality, by means of DNA content, appears reasonable as regards the granulocytes and monocytes. DNA hypodiploid lymphocytes, on the other hand, might be small blasts (stem cells) or dying cell populations of unknown origin...