T Gustafsson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Exercise-induced angiogenesis-related growth and transcription factors in skeletal muscle, and their modification in muscle pathology
    T Gustafsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Front Biosci 6:D75-89. 2001
  2. ncbi request reprint Increased expression of vascular endothelial growth factor in human skeletal muscle in response to short-term one-legged exercise training
    T Gustafsson
    Department of Medical Library Sciences and Technology, Huddinge University Hospital, Karolinska Institutet, 141 86 Stockholm, Sweden
    Pflugers Arch 444:752-9. 2002
  3. pmc Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans
    James A Timmons
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, SE171 77, Sweden
    BMC Biol 3:19. 2005
  4. ncbi request reprint Increased expression of VEGF following exercise training in patients with heart failure
    T Gustafsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Eur J Clin Invest 31:362-6. 2001
  5. ncbi request reprint Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heart
    A J Siddiqui
    Department of Cardiology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
    Am J Hypertens 18:1347-52. 2005
  6. doi request reprint Training response of mitochondrial transcription factors in human skeletal muscle
    J Norrbom
    Division of Clinical Physiology, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    Acta Physiol (Oxf) 198:71-9. 2010
  7. ncbi request reprint Simvastatin enhances myocardial angiogenesis induced by vascular endothelial growth factor gene transfer
    A J Siddiqui
    Department of Cardiology, Clinical Research Center, Huddinge, Karolinska Institute, Karolinska University Hospital, 141 86 Stockholm, Sweden
    J Mol Cell Cardiol 37:1235-44. 2004
  8. doi request reprint Alternative splice variant PGC-1α-b is strongly induced by exercise in human skeletal muscle
    J Norrbom
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Am J Physiol Endocrinol Metab 301:E1092-8. 2011
  9. ncbi request reprint The influence of physical training on the angiopoietin and VEGF-A systems in human skeletal muscle
    T Gustafsson
    Department of Laboratory Medicine, C1 88 Clinical Physiology, Karolinska University Hospital, Huddinge 14186, Stockholm, Sweden
    J Appl Physiol 103:1012-20. 2007
  10. ncbi request reprint Expression of oestrogen receptor alpha and beta is higher in skeletal muscle of highly endurance-trained than of moderately active men
    A Wiik
    Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden
    Acta Physiol Scand 184:105-12. 2005

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Exercise-induced angiogenesis-related growth and transcription factors in skeletal muscle, and their modification in muscle pathology
    T Gustafsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Front Biosci 6:D75-89. 2001
    ....
  2. ncbi request reprint Increased expression of vascular endothelial growth factor in human skeletal muscle in response to short-term one-legged exercise training
    T Gustafsson
    Department of Medical Library Sciences and Technology, Huddinge University Hospital, Karolinska Institutet, 141 86 Stockholm, Sweden
    Pflugers Arch 444:752-9. 2002
    ..In contrast to increased tissue VEGF expression, the arterial and femoral venous plasma levels of VEGF were decreased by training, which may indicate an exercise-induced enhancement of the peripheral uptake of VEGF...
  3. pmc Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans
    James A Timmons
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, SE171 77, Sweden
    BMC Biol 3:19. 2005
    ....
  4. ncbi request reprint Increased expression of VEGF following exercise training in patients with heart failure
    T Gustafsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Eur J Clin Invest 31:362-6. 2001
    ....
  5. ncbi request reprint Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heart
    A J Siddiqui
    Department of Cardiology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
    Am J Hypertens 18:1347-52. 2005
    ..The aim of this study was to test the hypothesis that angiotensin converting enzyme inhibition or angiotensin II antagonism can counteract cardiac human vascular endothelial growth factor-A165 (phVEGF-A165) induced angiogenesis...
  6. doi request reprint Training response of mitochondrial transcription factors in human skeletal muscle
    J Norrbom
    Division of Clinical Physiology, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    Acta Physiol (Oxf) 198:71-9. 2010
    ..The present study aimed to investigate the influence of exercise and training status on key mt transcription factors in relation to oxidative capacity in human skeletal muscle...
  7. ncbi request reprint Simvastatin enhances myocardial angiogenesis induced by vascular endothelial growth factor gene transfer
    A J Siddiqui
    Department of Cardiology, Clinical Research Center, Huddinge, Karolinska Institute, Karolinska University Hospital, 141 86 Stockholm, Sweden
    J Mol Cell Cardiol 37:1235-44. 2004
    ..These effects occurred concurrently with simvastatin-induced stimulation of the VEGF system, increased eNOS production and reduction in p38 MAPK phosphorylation...
  8. doi request reprint Alternative splice variant PGC-1α-b is strongly induced by exercise in human skeletal muscle
    J Norrbom
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Am J Physiol Endocrinol Metab 301:E1092-8. 2011
    ....
  9. ncbi request reprint The influence of physical training on the angiopoietin and VEGF-A systems in human skeletal muscle
    T Gustafsson
    Department of Laboratory Medicine, C1 88 Clinical Physiology, Karolinska University Hospital, Huddinge 14186, Stockholm, Sweden
    J Appl Physiol 103:1012-20. 2007
    ..It further establish that hypoxia/ischemia-related metabolic perturbation is likely to be involved as stimuli in this process in human skeletal muscle...
  10. ncbi request reprint Expression of oestrogen receptor alpha and beta is higher in skeletal muscle of highly endurance-trained than of moderately active men
    A Wiik
    Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden
    Acta Physiol Scand 184:105-12. 2005
    ..It was hypothesized that ERs are expressed at a higher level in a group with higher oxidative capacity, and that such an enhanced expression would parallel expression of the angiogenic factor -- vascular endothelial growth factor (VEGF)...
  11. ncbi request reprint Mitochondrial transcription factor A and respiratory complex IV increase in response to exercise training in humans
    J Bengtsson
    Section of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institutet, S-171 77 Stockholm, Sweden
    Pflugers Arch 443:61-6. 2001
    ....
  12. ncbi request reprint A single bout of exercise activates matrix metalloproteinase in human skeletal muscle
    E Rullman
    Department of Laboratory Medicine, Division of Clinical Physiology, C1 88, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden
    J Appl Physiol 102:2346-51. 2007
    ..Other mechanisms are responsible for the observed exercise-induced decrease in VEGF-A in plasma...
  13. ncbi request reprint Human skeletal muscle fibre type variations correlate with PPAR alpha, PPAR delta and PGC-1 alpha mRNA
    D K Krämer
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    Acta Physiol (Oxf) 188:207-16. 2006
    ..Our aim was therefore to investigate expression of those genes implicated in the regulation of oxidative fibre phenotypes in humans...
  14. ncbi request reprint Maximal oxygen uptake is not limited by a central nervous system governor
    T Brink-Elfegoun
    Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden
    J Appl Physiol 102:781-6. 2007
    ....
  15. doi request reprint Elevations of local intravascular pressures release vasoactive substances in humans
    T Gustafsson
    Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden
    Clin Physiol Funct Imaging 33:38-44. 2013
    ..The local release of the vasoconstrictors ET-1 and Ang-II in response to markedly increased distending pressure may reflect one mechanism behind adaptation to acute and long-term changes in intravascular pressure...
  16. doi request reprint Effects of 3 days unloading on molecular regulators of muscle size in humans
    T Gustafsson
    Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, 141 86 Stockholm, Sweden
    J Appl Physiol 109:721-7. 2010
    ..Further, the reported difference in gene expression pattern across muscles suggests that mechanisms regulating protein content in human skeletal muscle are influenced by phenotype and/or function...
  17. ncbi request reprint Local changes in the insulin-like growth factor system in human skeletal muscle assessed by microdialysis and arterio-venous differences technique
    U Berg
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Karolinska Institute, Astrid Lindgren Children s Hospital, Stockholm, Sweden
    Growth Horm IGF Res 16:217-23. 2006
    ..We suggest that an optimized and validated microdialysis technique for determination of local IGF-I may be advantageous in future studies...
  18. ncbi request reprint Angiogenic effects of dual gene transfer of bFGF and PDGF-BB after myocardial infarction
    X Hao
    Department of Cardiology, Karolinska Institutet, Huddinge University Hospital, Stockholm SE 141 86, Sweden
    Biochem Biophys Res Commun 315:1058-63. 2004
    ..No cardiovascular side effects were observed after gene transfer...
  19. doi request reprint Circulating MMP-9 during exercise in humans
    E Rullman
    Department of Laboratory Medicine, Division of Clinical Physiology C1 88 Karolinska Institutet, Karolinska University Hospital, Huddinge 141 86, Stockholm, Sweden
    Eur J Appl Physiol 113:1249-55. 2013
    ..No detectable release of MMP-9 was observed, suggesting that the increase in plasma MMP-9 could come from a source other than the skeletal muscle...
  20. ncbi request reprint Interstitial IGF-I in exercising skeletal muscle in women
    U Berg
    Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Astrid Lindgren Children s Hospital, SE 171 76 Stockholm, Sweden
    Eur J Endocrinol 157:427-35. 2007
    ..To study interstitial IGF-I concentrations in resting and exercising skeletal muscle in relation to the circulating components of the IGF-IGF binding protein (IGFBP) system...
  21. ncbi request reprint VEGF-A splice variants and related receptor expression in human skeletal muscle following submaximal exercise
    T Gustafsson
    Karolinska Institute, Berzelius vag 35, Stockholm 171 77, Sweden
    J Appl Physiol 98:2137-46. 2005
    ..Our findings also indicate that all three receptor genes exhibit different pretranslational regulation, in response to exercise in humans...