Research Topics
Genomes and GenesSpecies | T GustafssonSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Exercise-induced angiogenesis-related growth and transcription factors in skeletal muscle, and their modification in muscle pathologyT Gustafsson
Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Front Biosci 6:D75-89. 2001....
Increased expression of vascular endothelial growth factor in human skeletal muscle in response to short-term one-legged exercise trainingT Gustafsson
Department of Medical Library Sciences and Technology, Huddinge University Hospital, Karolinska Institutet, 141 86 Stockholm, Sweden
Pflugers Arch 444:752-9. 2002..In contrast to increased tissue VEGF expression, the arterial and femoral venous plasma levels of VEGF were decreased by training, which may indicate an exercise-induced enhancement of the peripheral uptake of VEGF...
Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humansJames A Timmons
Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, SE171 77, Sweden
BMC Biol 3:19. 2005....
Increased expression of VEGF following exercise training in patients with heart failureT Gustafsson
Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Eur J Clin Invest 31:362-6. 2001....
Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heartA J Siddiqui
Department of Cardiology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
Am J Hypertens 18:1347-52. 2005..The mechanism of inhibition is a combination of inhibition of cardiac hVEGF-A expression and of decreased endogenous expression of the mVEGF ligand and receptor system...
Training response of mitochondrial transcription factors in human skeletal muscleJ Norrbom
Division of Clinical Physiology, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
Acta Physiol (Oxf) 198:71-9. 2010..The present study aimed to investigate the influence of exercise and training status on key mt transcription factors in relation to oxidative capacity in human skeletal muscle...
Alternative splice variant PGC-1α-b is strongly induced by exercise in human skeletal muscleJ Norrbom
Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Am J Physiol Endocrinol Metab 301:E1092-8. 2011....
The influence of physical training on the angiopoietin and VEGF-A systems in human skeletal muscleT Gustafsson
Department of Laboratory Medicine, C1 88 Clinical Physiology, Karolinska University Hospital, Huddinge 14186, Stockholm, Sweden
J Appl Physiol 103:1012-20. 2007..It further establish that hypoxia/ischemia-related metabolic perturbation is likely to be involved as stimuli in this process in human skeletal muscle...
Simvastatin enhances myocardial angiogenesis induced by vascular endothelial growth factor gene transferA J Siddiqui
Department of Cardiology, Clinical Research Center, Huddinge, Karolinska Institute, Karolinska University Hospital, 141 86 Stockholm, Sweden
J Mol Cell Cardiol 37:1235-44. 2004..These effects occurred concurrently with simvastatin-induced stimulation of the VEGF system, increased eNOS production and reduction in p38 MAPK phosphorylation...
Mitochondrial transcription factor A and respiratory complex IV increase in response to exercise training in humansJ Bengtsson
Section of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institutet, S-171 77 Stockholm, Sweden
Pflugers Arch 443:61-6. 2001....
Expression of oestrogen receptor alpha and beta is higher in skeletal muscle of highly endurance-trained than of moderately active menA Wiik
Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden
Acta Physiol Scand 184:105-12. 2005....
A single bout of exercise activates matrix metalloproteinase in human skeletal muscleE Rullman
Department of Laboratory Medicine, Division of Clinical Physiology, C1 88, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden
J Appl Physiol 102:2346-51. 2007..Other mechanisms are responsible for the observed exercise-induced decrease in VEGF-A in plasma...
Human skeletal muscle fibre type variations correlate with PPAR alpha, PPAR delta and PGC-1 alpha mRNAD K Krämer
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Acta Physiol (Oxf) 188:207-16. 2006..Our aim was therefore to investigate expression of those genes implicated in the regulation of oxidative fibre phenotypes in humans...
Maximal oxygen uptake is not limited by a central nervous system governorT Brink Elfegoun
Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden
J Appl Physiol 102:781-6. 2007....
Local changes in the insulin-like growth factor system in human skeletal muscle assessed by microdialysis and arterio-venous differences techniqueU Berg
Department of Woman and Child Health, Pediatric Endocrinology Unit, Karolinska Institute, Astrid Lindgren Children s Hospital, Stockholm, Sweden
Growth Horm IGF Res 16:217-23. 2006..We suggest that an optimized and validated microdialysis technique for determination of local IGF-I may be advantageous in future studies...
Effects of 3 days unloading on molecular regulators of muscle size in humansT Gustafsson
Department of Laboratory Medicine, Section of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, 141 86 Stockholm, Sweden
J Appl Physiol 109:721-7. 2010..Further, the reported difference in gene expression pattern across muscles suggests that mechanisms regulating protein content in human skeletal muscle are influenced by phenotype and/or function...
Angiogenic effects of dual gene transfer of bFGF and PDGF-BB after myocardial infarctionX Hao
Department of Cardiology, Karolinska Institutet, Huddinge University Hospital, Stockholm SE-141 86, Sweden
Biochem Biophys Res Commun 315:1058-63. 2004..No cardiovascular side effects were observed after gene transfer...
Interstitial IGF-I in exercising skeletal muscle in womenU Berg
Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute, Astrid Lindgren Children s Hospital, SE 171 76 Stockholm, Sweden
Eur J Endocrinol 157:427-35. 2007..To study interstitial IGF-I concentrations in resting and exercising skeletal muscle in relation to the circulating components of the IGF-IGF binding protein (IGFBP) system...
VEGF-A splice variants and related receptor expression in human skeletal muscle following submaximal exerciseT Gustafsson
Karolinska Institute, Berzelius vag 35, Stockholm 171 77, Sweden
J Appl Physiol 98:2137-46. 2005..Our findings also indicate that all three receptor genes exhibit different pretranslational regulation, in response to exercise in humans...
