Kristina Gemzell-Danielsson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Misoprostol: first-line therapy for incomplete miscarriage in the developing world
    K Gemzell-Danielsson
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Karolinska Institutet, Stockholm, Sweden
    BJOG 114:1337-9. 2007
  2. ncbi request reprint Contraception following abortion and the treatment of incomplete abortion
    Kristina Gemzell-Danielsson
    Department of Women and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden Electronic address
    Int J Gynaecol Obstet 126:S52-5. 2014
  3. pmc Emergency contraception: potential role of ulipristal acetate
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Stockholm, Sweden
    Int J Womens Health 2:53-61. 2010
  4. pmc Early versus delayed insertion of intrauterine contraception after medical abortion - a randomized controlled trial
    Ingrid Sääv
    Department of Women s and Children s Health, Division of Obstetrics and Gynaecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    PLoS ONE 7:e48948. 2012
  5. pmc Management of pain associated with the insertion of intrauterine contraceptives
    K Gemzell-Danielsson
    Department of Women s and Children s Health, Karolinska Institutet, Karolinska University Hospital, SE 17176 Stockholm, Sweden
    Hum Reprod Update 19:419-27. 2013
  6. doi request reprint Emergency contraception -- mechanisms of action
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, S 171 76 Stockholm, Sweden
    Contraception 87:300-8. 2013
  7. doi request reprint Use of contraceptive methods and contraceptive recommendations among health care providers actively involved in contraceptive counseling -- results of an international survey in 10 countries
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, 17176 Stockholm, Sweden
    Contraception 86:631-8. 2012
  8. doi request reprint A randomized, phase II study describing the efficacy, bleeding profile, and safety of two low-dose levonorgestrel-releasing intrauterine contraceptive systems and Mirena
    Kristina Gemzell-Danielsson
    Division of Obstetrics and Gynecology, Department of Women s and Children s Health, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Fertil Steril 97:616-22.e1-3. 2012
  9. ncbi request reprint [Valuable drug for women in poor countries scraped--why?]
    Kristina Gemzell Danielsson
    Karolinska Universitetssjukhuset, Solna
    Lakartidningen 103:3901-2. 2006
  10. doi request reprint Mechanism of action of emergency contraception
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, S 171 76 Stockholm, Sweden
    Contraception 82:404-9. 2010

Collaborators

Detail Information

Publications63

  1. ncbi request reprint Misoprostol: first-line therapy for incomplete miscarriage in the developing world
    K Gemzell-Danielsson
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Karolinska Institutet, Stockholm, Sweden
    BJOG 114:1337-9. 2007
  2. ncbi request reprint Contraception following abortion and the treatment of incomplete abortion
    Kristina Gemzell-Danielsson
    Department of Women and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden Electronic address
    Int J Gynaecol Obstet 126:S52-5. 2014
    ....
  3. pmc Emergency contraception: potential role of ulipristal acetate
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Stockholm, Sweden
    Int J Womens Health 2:53-61. 2010
    ....
  4. pmc Early versus delayed insertion of intrauterine contraception after medical abortion - a randomized controlled trial
    Ingrid Sääv
    Department of Women s and Children s Health, Division of Obstetrics and Gynaecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    PLoS ONE 7:e48948. 2012
    ..Intrauterine contraceptives (IUC) provide highly effective, reversible, long-acting contraception. However, the effects of timing of IUC insertion after medical abortion are not known...
  5. pmc Management of pain associated with the insertion of intrauterine contraceptives
    K Gemzell-Danielsson
    Department of Women s and Children s Health, Karolinska Institutet, Karolinska University Hospital, SE 17176 Stockholm, Sweden
    Hum Reprod Update 19:419-27. 2013
    ..This review critically evaluates the evidence for pain management strategies, formulates evidence-based recommendations and identifies data gaps and areas for further research...
  6. doi request reprint Emergency contraception -- mechanisms of action
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, S 171 76 Stockholm, Sweden
    Contraception 87:300-8. 2013
    ..An additional effect on the endometrium as occurs for the Cu-IUD, but not for the hormonal alternatives, seems to increase the efficacy of the method...
  7. doi request reprint Use of contraceptive methods and contraceptive recommendations among health care providers actively involved in contraceptive counseling -- results of an international survey in 10 countries
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, 17176 Stockholm, Sweden
    Contraception 86:631-8. 2012
    ....
  8. doi request reprint A randomized, phase II study describing the efficacy, bleeding profile, and safety of two low-dose levonorgestrel-releasing intrauterine contraceptive systems and Mirena
    Kristina Gemzell-Danielsson
    Division of Obstetrics and Gynecology, Department of Women s and Children s Health, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Fertil Steril 97:616-22.e1-3. 2012
    ..To identify an appropriate dose for a new contraceptive levonorgestrel intrauterine system (LNG-IUS)...
  9. ncbi request reprint [Valuable drug for women in poor countries scraped--why?]
    Kristina Gemzell Danielsson
    Karolinska Universitetssjukhuset, Solna
    Lakartidningen 103:3901-2. 2006
  10. doi request reprint Mechanism of action of emergency contraception
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, S 171 76 Stockholm, Sweden
    Contraception 82:404-9. 2010
    ..LNG-EC has no effect on endometrial development or function. In an in vitro model, it was demonstrated that LNG did not interfere with blastocyst function or implantation...
  11. doi request reprint Second trimester medical abortion with mifepristone-misoprostol and misoprostol alone: a review of methods and management
    Kristina Gemzell-Danielsson
    Department of Woman and Child Health, Division of Obstetrics and Gynaecology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Reprod Health Matters 16:162-72. 2008
    ..Future studies should focus on improving pain management, the treatment of women with failed medical abortion after 24 hours, and the safety of medical abortion regimens in women with a previous caesarean section or uterine scar...
  12. doi request reprint Comprehensive counseling about combined hormonal contraceptives changes the choice of contraceptive methods: results of the CHOICE program in Sweden
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 90:869-77. 2011
    ..To study the influence of counseling on women's contraceptive decisions...
  13. doi request reprint Recent developments in the clinical use of the levonorgestrel-releasing intrauterine system
    Kristina Gemzell-Danielsson
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institute Karolinska University Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 90:1177-88. 2011
    ..In treatment of heavy menstrual bleeding, the LNG-IUS appears to be one of the most effective and cost-effective methods...
  14. ncbi request reprint Preference and acceptability of oral versus vaginal administration of misoprostol in medical abortion with mifepristone
    Caroline Arvidsson
    Department of Obstetrics and Gynecology, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
    Eur J Obstet Gynecol Reprod Biol 123:87-91. 2005
    ..To compare the experience of pain, need of analgesic interventions, preference and acceptability in medical abortion up to 49 days of amenorrhea with mifepristone and orally versus vaginally administered misoprostol...
  15. ncbi request reprint Mifepristone, but not levonorgestrel, inhibits human blastocyst attachment to an in vitro endometrial three-dimensional cell culture model
    P G L Lalitkumar
    Division of Obstetrics and Gynecology, Department of Woman and Child Health, Karolinska Institutet, Karolinska University Hospital, S 171 76, Stockholm, Sweden
    Hum Reprod 22:3031-7. 2007
    ..This study investigates the effect of levonorgestrel and mifepristone on attachment of human embryos to an in vitro endometrial construct...
  16. ncbi request reprint Progesterone receptor isoform B in the human fallopian tube and endometrium following mifepristone
    Xiaoxi Sun
    Department of Woman and Child Health, Division for Obstetrics and Gynecology, Karolinska Hospital Institute, S 171 76, Stockholm, Sweden
    Contraception 67:319-26. 2003
    ..These results further support the hypothesis that the contraceptive effect of mifepristone when given postovulatory is primarily due to alteration of the peri-implantation milieu influencing endometrial receptivity...
  17. ncbi request reprint Studies on uterine contractility following mifepristone and various routes of misoprostol
    Kristina Gemzell-Danielsson
    Department of Obstetrics and Gynecology, Karolinska University Hospital, Karolinska Institute, SE 171 76 Stockholm, Sweden
    Contraception 74:31-5. 2006
    ..Recently, a new oral slow-release preparation of misoprostol has been studied. Future studies will show whether prostaglandin analogues with a prolonged effect on the myometrium may further improve the regimens for medical abortion...
  18. doi request reprint Teaching pelvic examination technique using professional patients: a controlled study evaluating students' skills
    Kjell Wånggren
    Department of Women s and Children s Health, Uppsala University, Akademiska Hospital, Uppsala, Sweden
    Acta Obstet Gynecol Scand 89:1298-303. 2010
    ..To compare the skills in pelvic examination technique between students who have had training with professional patients and a control group of students trained using clinical patients...
  19. ncbi request reprint Expression of aquaporin-1 in endometrial blood vessels in menorrhagia
    Miriam Mints
    Department of Clinical Science, Division of Obstetrics and Gynecology, Karolinska University Hospital Huddinge, Karolinska Institutet, S 14186 Stockholm, Sweden
    Int J Mol Med 19:407-11. 2007
    ..006). Thus, the deregulation of aquaporin-1 in menorrhagia may be involved in abnormal endometrial vascular growth and permeability...
  20. doi request reprint Measurement of luminal nitric oxide in the uterine cavity using a silicon balloon catheter
    Angelos Sioutas
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Nitric Oxide 24:213-6. 2011
    ..The levels of nitric oxide are increased in women diagnosed with pelvic inflammatory disease already after an incubation time of 2 min...
  21. ncbi request reprint Action of mifepristone on the expression of insulin-like growth factor binding protein-1 mRNA and protein during the early luteal phase in the human oviduct
    Xiaoyan Qiu
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden
    Fertil Steril 80:776-82. 2003
    ..To investigate the effects of the antiprogestin mifepristone on the expression of insulin-like growth factor binding protein-1 (IGFBP-1) mRNA and protein during the early luteal phase in the human oviduct...
  22. doi request reprint Medical abortion in lactating women--low levels of mifepristone in breast milk
    Ingrid Sääv
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 89:618-22. 2010
    ..In addition, serum samples were collected on day 3 (n = 4). Main outcome measures. The levels of mifepristone, quantified using radioimmunoassay...
  23. doi request reprint Medical students learning the pelvic examination: evaluation of a clinical patient model
    Kjell Wånggren
    Department of Women s and Children s Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 89:1304-9. 2010
    ..To evaluate a clinical patient (CP) model for training in pelvic examination...
  24. ncbi request reprint Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone
    Xiao Xi Sun
    Division of Obstetrics and Gynecology, Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    Fertil Steril 85:171-8. 2006
    ..To study the effect of mifepristone on heparin-binding epidermal growth factor (HB-EGF) and its receptors HER1 and HER4 in the fallopian tube and in the endometrium...
  25. ncbi request reprint Aquaporin 1 is expressed in the human endometrium during normal cycle and increases after mifepristone treatment
    Anna Hildenbrand
    Division of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    Int J Mol Med 22:49-53. 2008
    ..The presence of AQP1 was also confirmed using RT-PCR. The changes in AQP1 expression could contribute to the reduced bleeding seen following mifepristone treatment and could be an effect of either antagonizing progesterone or cortisol...
  26. ncbi request reprint Expression of aquaporin 2 in human endometrium
    Anna Hildenbrand
    Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    Fertil Steril 86:1452-8. 2006
    ..To study the expression of aquaporin-2 (AQP2) in human endometrium...
  27. ncbi request reprint Effects of mifepristone on expression of endothelial nitric oxide synthase in human endometrium during the implantation phase
    Xiaoxi Sun
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden
    Fertil Steril 80:1454-60. 2003
    ..To investigate the effects of the antiprogestin mifepristone on expression of endothelial (eNOS) nitric oxide synthase in human endometrium during the implantation phase...
  28. ncbi request reprint The effect of orally and vaginally administered misoprostol on inflammatory mediators and cervical ripening during early pregnancy
    Annette Aronsson
    Department of Woman and Child Health, Division for Obstetrics and Gynecology, Karolinska Institute, S 171 76 Stockholm, Sweden
    Contraception 72:33-9. 2005
    ..The objective of the present study was to investigate the effect of vaginally and orally administered misoprostol on the local cervical inflammatory response...
  29. doi request reprint Assessment of significant factors affecting acceptability of home administration of misoprostol for medical abortion
    Helena Kopp Kallner
    Division of Obstetrics and Gynaecology, Department of Woman and Child Health, Karolinska Institutet Karolinska University Hospital, 171 77 Stockholm, Sweden
    Contraception 85:394-7. 2012
    ..The objective of this study was therefore to assess factors affecting acceptability and experience of home use of misoprostol for medical abortion up to 63 days' gestation...
  30. doi request reprint Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT
    Sujata Lalitkumar
    Department of Women s and Children s Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Fertil Steril 100:1160-9. 2013
    ..To study the effect of polyethylene glycated leukemia inhibitory factor (LIF) antagonist (PEGLA) in the human blastocyst viability and implantation process...
  31. doi request reprint Effect of levonorgestrel and mifepristone on endometrial receptivity markers in a three-dimensional human endometrial cell culture model
    Chun Xia Meng
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Fertil Steril 91:256-64. 2009
    ..To investigate the effect of levonorgestrel and mifepristone on the expression of endometrial receptivity markers in a three-dimensional endometrial construct...
  32. ncbi request reprint Mechanisms of action of mifepristone when used for emergency contraception
    Kristina Gemzell-Danielsson
    Department of Woman and Child Health, Division for Obstetrics and Gynecology, Karolinska Hospital Institute, S 171 76, Stockholm, Sweden
    Contraception 68:471-6. 2003
    ....
  33. doi request reprint Regional differences in surgical intervention following medical termination of pregnancy provided by telemedicine
    Rebecca Gomperts
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 91:226-31. 2012
    ..Analysis of factors influencing surgical intervention rate after home medical termination of pregnancy (TOP) by women in countries without access to safe services using the telemedical service 'Women on Web'...
  34. ncbi request reprint Effect of emergency contraception with levonorgestrel or mifepristone on ovarian function
    Lena Marions
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Hospital Institute, 17176 Stockholm, Sweden
    Contraception 69:373-7. 2004
    ..This study indicates that, when used for EC, LNG or MIF administered prior to ovulation acts through an impaired ovulatory process and luteal function...
  35. ncbi request reprint Intrauterine nitric oxide in pelvic inflammatory disease
    Angelos Sioutas
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Fertil Steril 89:948-52. 2008
    ..To measure nitric oxide gas directly in the uterus of healthy women and patients with suspected pelvic inflammatory disease...
  36. ncbi request reprint Two low-dose levonorgestrel intrauterine contraceptive systems: a randomized controlled trial
    Anita Nelson
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, California the Sexual Health Clinic Family Federation of Finland, Vaestoliitto, Helsinki, Finland the Department of Obstetrics and Gynecology, Foothills Hospital, University of Calgary, Calgary, Alberta, Canada Bayer Pharma AG, MülleBerlin, Germany Bayer HealthCare Pharmaceuticals, Montville, New Jersey and the Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
    Obstet Gynecol 122:1205-13. 2013
    ..To evaluate the efficacy and safety of two low-dose levonorgestrel intrauterine contraceptive systems...
  37. doi request reprint Emergency contraception
    Kristina Gemzell-Danielsson
    Department of Woman and Child Health, Karolinska Institutet, WHO centre, Karolinska University Hospital, Stockholm, Sweden
    Gynecol Endocrinol 29:1-14. 2013
    ..A pre-existing pregnancy must be excluded. Possible contraindications and drug interactions must be considered according to the individual special product informations...
  38. ncbi request reprint Effect of letrozole on uterine tonus and contractility: a randomized controlled trial
    Helena Kopp Kallner
    Division of Obstetrics and Gynaecology, Department of Women s and Children s Health, Karolinska Institutet Karolinska University Hospital, 171 77 Stockholm, Sweden
    Contraception 86:419-24. 2012
    ..It has been shown to increase efficacy in medical abortion when used with misoprostol. This study investigated if letrozole acts as an abortifacient due to a synergistic effect with misoprostol on uterine contractility...
  39. doi request reprint An historical overview of second trimester abortion methods
    Marc Bygdeman
    Department of Woman and Child Health, Division of Obstetrics and Gynaecology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Reprod Health Matters 16:196-204. 2008
    ....
  40. doi request reprint Expressions of steroid receptors and Ki67 in first-trimester decidua and chorionic villi exposed to levonorgestrel used for emergency contraception
    Chun Xia Meng
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Fertil Steril 91:1420-3. 2009
    ....
  41. ncbi request reprint The effect of mifepristone on the expression of insulin-like growth factor binding protein-1, prolactin and progesterone receptor mRNA and protein during the implantation phase in human endometrium
    Xiaoyan Qiu
    Division of Obstetrics and Gynecology, Department of Woman and Child Health, Karolinska Hospital, S 171 76 Stockholm, Sweden
    Mol Hum Reprod 8:998-1004. 2002
    ..Our findings provide further insight into the regulation of IGFBP-1 and prolactin by PR in the human endometrium in vivo...
  42. ncbi request reprint Acceptability of home-use of misoprostol in medical abortion
    Christian Fiala
    Division for Obstetrics and Gynaecology, Department of Woman and Child Health, Karolinska Hospital Institute, S 171 76 Stockholm, Sweden
    Contraception 70:387-92. 2004
    ..Home-use of misoprostol would reduce the number of visits and improve access to medical abortion. We evaluated acceptance of home-use of misoprostol among women and their partners...
  43. ncbi request reprint Perceptions of contraception, non-protection and induced abortion among a sample of urban Swedish teenage girls: focus group discussions
    Caroline Thorsén
    Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    Eur J Contracept Reprod Health Care 11:302-9. 2006
    ..To explore the attitudes of teenage girls towards contraception and induced abortion in order to better understand underlying reasons for non-protection...
  44. doi request reprint Emergency contraception
    P G L Lalitkumar
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet WHO Collaborating Center, Karolinska University Hospital, Stockholm, Sweden
    Best Pract Res Clin Endocrinol Metab 27:91-101. 2013
    ..To increase efficacy future studies should focus on EC methods that target the endometrium...
  45. doi request reprint Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1
    Johanna Sundqvist
    Department of Women s and Children s Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Fertil Steril 95:437-40. 2011
    ..This study investigates the association of rheumatoid arthritis-associated single nucleotide polymorphisms in endometriosis. We found an association of CCL21 (rs2812378) and HLA-DRB1 (rs660895) with moderate to severe endometriosis...
  46. ncbi request reprint Teaching medical students gynaecological examination using professional patients-evaluation of students' skills and feelings
    Kjell Wånggren
    Department of Woman and Child Health, Division of Obstetrics and Gynaecology, Karolinska Hospital Institute, Stockholm, Sweden
    Med Teach 27:130-5. 2005
    ..It is strongly recommended that this type of programme with professional patients should be used for teaching gynaecological examination techniques to medical students...
  47. doi request reprint Measurement of nitric oxide in the vagina
    Angelos Sioutas
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 87:1055-9. 2008
    ..The objective of this study is to measure NO gas directly in the vaginal lumen of healthy women and in patients with vaginitis...
  48. doi request reprint Emerging indications for the levonorgestrel-releasing intrauterine system (LNG-IUS)
    Oskari Heikinheimo
    Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
    Acta Obstet Gynecol Scand 91:3-9. 2012
    ..Further studies are needed to examine the full potential of the LNG-IUS in such common clinical situations...
  49. ncbi request reprint Emergency contraception with mifepristone and levonorgestrel: mechanism of action
    Lena Marions
    Department of Women and Child Health, Karolinska Hospital, Stockholm, Sweden
    Obstet Gynecol 100:65-71. 2002
    ..To study the effect of mifepristone and levonorgestrel on ovarian function and endometrial development in doses effective as emergency contraception...
  50. ncbi request reprint Effects of misoprostol on uterine contractility following different routes of administration
    A Aronsson
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Karolinska Institute Hospital, S 171 76 Stockholm, Sweden
    Hum Reprod 19:81-4. 2004
    ..The effect of misoprostol administered by different routes on pregnant uterine contractility was investigated...
  51. ncbi request reprint Effects of slow release misoprostol on uterine contractility in early pregnancy
    C Fiala
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Stockholm, Sweden
    Hum Reprod 20:2648-52. 2005
    ..The effect of a novel slow release form of misoprostol (SR misoprostol) on uterine activity during early pregnancy was investigated in a pilot study...
  52. ncbi request reprint Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects
    O S Tang
    Department of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong SAR, China
    Int J Gynaecol Obstet 99:S160-7. 2007
    ..These studies can help to discover the optimal dose and route of administration of misoprostol for individual clinical applications. Misoprostol is a safe drug but serious complications and teratogenicity can occur with unsupervised use...
  53. ncbi request reprint Sublingual compared with oral misoprostol for cervical dilatation prior to vacuum aspiration: a randomized comparison
    A Aronsson
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Karolinska Institute, S 171 76 Stockholm, Sweden
    Contraception 69:165-9. 2004
    ..It was shown that sublingual administration is more effective than oral administration of misoprostol for cervical priming and is associated with less blood loss but a higher frequency of side effects...
  54. ncbi request reprint Treatment of incomplete abortion and miscarriage with misoprostol
    J Blum
    Gynuity Health Projects, New York, NY 10010, USA
    Int J Gynaecol Obstet 99:S186-9. 2007
    ..A single dose of misoprostol 600 microg oral is recommended for treatment of incomplete abortion in women presenting with a uterine size equivalent to 12 weeks gestation...
  55. ncbi request reprint Pharmacokinetics of a novel oral slow-release form of misoprostol
    C Fiala
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Hum Reprod 20:3414-8. 2005
    ..The pharmacokinetics of a novel slow-release (SR) misoprostol was studied and compared to conventional misoprostol...
  56. ncbi request reprint The effect of non-steroidal anti-inflammatory drugs on medical abortion with mifepristone and misoprostol at 13-22 weeks gestation
    C Fiala
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Clinical Epidemiology Unit, Karolinska Institute, 171 76 Stockholm, Sweden
    Hum Reprod 20:3072-7. 2005
    ....
  57. ncbi request reprint Home use of two doses of misoprostol after mifepristone for medical abortion: a pilot study in Sweden and France
    W H Clark
    Gynuity Health Projects, New York, USA
    Eur J Contracept Reprod Health Care 10:184-91. 2005
    ..To test the feasibility, safety, and efficacy of home use of two doses of misoprostol for medical abortion (MA) in European settings...
  58. ncbi request reprint Pharmacokinetic profiles up to 12 h after administration of vaginal, sublingual and slow-release oral misoprostol
    A Aronsson
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Karolinska University Hospital, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Hum Reprod 22:1912-8. 2007
    ..No study has so far evaluated the pharmacokinetics beyond 6 hours. Furthermore a new slow-release misoprostol formulation was included in the study...
  59. ncbi request reprint Misoprostol for the termination of pregnancy with a live fetus at 13 to 26 weeks
    P C Ho
    Department of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China
    Int J Gynaecol Obstet 99:S178-81. 2007
    ..Common side effects of misoprostol-induced termination of pregnancy include gastrointestinal side effects, abdominal cramps, bleeding, fever and chills. Complications may include infection or rarely rupture of uterus...
  60. ncbi request reprint Cervical priming with misoprostol prior to transcervical procedures
    C Fiala
    Gynmed Clinic, Vienna, Austria
    Int J Gynaecol Obstet 99:S168-71. 2007
    ..Higher doses or longer intervals do not improve the effect on the cervix. Pain is a frequent side effect, but usually responds well to NSAIDs. Other side effects are rare...
  61. ncbi request reprint Misoprostol to treat missed abortion in the first trimester
    K Gemzell-Danielsson
    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Int J Gynaecol Obstet 99:S182-5. 2007
    ..Bleeding may last for more than 14 days with additional days of light bleeding or spotting. The woman should be advised to contact a provider in case of heavy bleeding or signs of infection. A follow-up is recommended after 1 to 2 weeks...
  62. doi request reprint Using telemedicine for termination of pregnancy with mifepristone and misoprostol in settings where there is no access to safe services
    R J Gomperts
    Women on Waves, Amsterdam, The Netherlands
    BJOG 115:1171-5; discussion 1175-8. 2008
    ..8% of the women who did the medical TOP at home needed a vacuum aspiration. Telemedicine can provide an alternative to unsafe TOP. Outcomes of care are in the same range as TOP provided in outpatient settings...
  63. ncbi request reprint Cervical priming with sublingual misoprostol prior to insertion of an intrauterine device in nulliparous women: a randomized controlled trial
    I Sääv
    Department of Woman and Child Health, Division for Obstetrics and Gynaecology, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Hum Reprod 22:2647-52. 2007
    ..However, insertion of an IUD through a narrow cervix may be technically difficult. Misoprostol has been shown to be effective for cervical priming in non-pregnant women prior to hysteroscopy...