Affiliation: Karolinska Institutet
- Caffeine as a psychomotor stimulant: mechanism of actionG Fisone
Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden
Cell Mol Life Sci 61:857-72. 2004..The present review focuses on the effects of caffeine on striatal signal transduction and on their involvement in caffeine-mediated motor stimulation...
- Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32P Svenningsson
Departments of Physiology and Pharmacology Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Neurochem 75:248-57. 2000..These results demonstrate an important involvement of DARPP-32 in dopamine receptor-mediated regulation of gene expression both in striatal neurons, which are enriched in DARPP-32, and in pallidal neurons, which do not contain DARPP-32...
- Dopamine D(2) receptors regulate tyrosine hydroxylase activity and phosphorylation at Ser40 in rat striatumN Lindgren
Department of Neuroscience, Karolinska Institutet, , S-171 77, Stockholm, Sweden
Eur J Neurosci 13:773-80. 2001..They also provide a molecular mechanism accounting for the ability of dopamine D(2) autoreceptors to inhibit dopamine synthesis and release from nigrostriatal nerve terminals...
- Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptorsP Svenningsson
Department of Physiology, Karolinska Institutet, S 171 77 Stockholm, Sweden
Proc Natl Acad Sci U S A 97:1856-60. 2000..The results also underscore the fact that the adenosine system plays a role in the generation of responses to dopamine D(2) antagonists in vivo...
- Distribution, biochemistry and function of striatal adenosine A2A receptorsP Svenningsson
Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Prog Neurobiol 59:355-96. 1999..In the present review, current knowledge on the distribution, biochemistry and function of striatal A2A receptors is summarized...
- Pharmacological validation of a mouse model of l-DOPA-induced dyskinesiaM Lundblad
Wallenberg Neuroscience Centre, Section of Basal Ganglia Pathophysiology, BMC A11, S-221 84 Lund, Sweden
Exp Neurol 194:66-75. 2005..The present data indicate that the mouse AIMs are indeed a functional equivalent of l-DOPA-induced dyskinesia...
- Adenosine A2A receptors and basal ganglia physiologyS N Schiffmann
Laboratory of Neurophysiology, Universite Libre de Bruxelles, Campus Erasme, 808 Route de Lennik, CP601, 1070 Brussels, Belgium
Prog Neurobiol 83:277-92. 2007....