Bjorn Fischler

Summary

Affiliation: Karolinska University Hospital
Country: Sweden

Publications

  1. ncbi request reprint Cholestatic liver disease in adults may be due to an inherited defect in bile acid biosynthesis
    B Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, Sweden
    J Intern Med 262:254-62. 2007
  2. ncbi request reprint Hepatitis C virus infection
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Semin Fetal Neonatal Med 12:168-73. 2007
  3. ncbi request reprint Living-related liver transplantation in children--a single center evaluation of the outcome of donor candidates and recipients
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Pediatr Transplant 12:531-5. 2008
  4. ncbi request reprint Virus-specific T cell immune response in children and adolescents with chronic hepatitis B virus infection
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    J Pediatr Gastroenterol Nutr 45:75-83. 2007
  5. doi request reprint Early cytomegalovirus infection and the long-term outcome of biliary atresia
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, CLINTEC, Karolinska Intitutet, Stockholm, Sweden
    Acta Paediatr 98:1600-2. 2009
  6. ncbi request reprint Immunoglobulin deposits in liver tissue from infants with biliary atresia and the correlation to cytomegalovirus infection
    Bjorn Fischler
    Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    J Pediatr Surg 40:541-6. 2005
  7. doi request reprint Bile acids and coagulation factors: paradoxical association in children with chronic liver disease
    Maria Magnusson
    CLINTEC, Division of Pediatrics, Karolinska Institutet, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden
    Eur J Gastroenterol Hepatol 25:152-8. 2013
  8. doi request reprint Hepatobiliary scintigraphy during cholestatic and noncholestatic periods in patients with progressive familial intrahepatic cholestasis after partial external biliary diversion
    Henrik Arnell
    Division of Pediatrics, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Huddinge and Solna, Stockholm, Sweden
    J Pediatr Surg 46:467-72. 2011
  9. doi request reprint Occurrence and pattern of ocular disease in children with cholestatic disorders
    Kristina Teär Fahnehjelm
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Acta Ophthalmol 89:143-50. 2011
  10. doi request reprint Follow-up in children with progressive familial intrahepatic cholestasis after partial external biliary diversion
    Henrik Arnell
    Department of Pediatrics, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    J Pediatr Gastroenterol Nutr 51:494-9. 2010

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Cholestatic liver disease in adults may be due to an inherited defect in bile acid biosynthesis
    B Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, Sweden
    J Intern Med 262:254-62. 2007
    ..An increasing number of treatable inborn errors of bile acid synthesis have been described, primarily in infants with severe cholestatic liver disease...
  2. ncbi request reprint Hepatitis C virus infection
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Semin Fetal Neonatal Med 12:168-73. 2007
    ..Treatment combinations of interferon and ribavirin seem to be at least as effective in children as in adults. However, the negative effect on growth of interferon requires specific attention by paediatricians...
  3. ncbi request reprint Living-related liver transplantation in children--a single center evaluation of the outcome of donor candidates and recipients
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Pediatr Transplant 12:531-5. 2008
    ..The fact that parents of BA patients have potential liver pathology may be of importance for the understanding of the etiology of the disease and have possible implications for the choice of donors...
  4. ncbi request reprint Virus-specific T cell immune response in children and adolescents with chronic hepatitis B virus infection
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    J Pediatr Gastroenterol Nutr 45:75-83. 2007
    ..To study the hepatitis B-specific T cell-mediated immune response in chronically infected children and adolescents...
  5. doi request reprint Early cytomegalovirus infection and the long-term outcome of biliary atresia
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, CLINTEC, Karolinska Intitutet, Stockholm, Sweden
    Acta Paediatr 98:1600-2. 2009
    ..To study the impact of ongoing cytomegalovirus (CMV) infection at presentation of biliary atresia (BA) on the long-term outcome after Kasai procedure...
  6. ncbi request reprint Immunoglobulin deposits in liver tissue from infants with biliary atresia and the correlation to cytomegalovirus infection
    Bjorn Fischler
    Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    J Pediatr Surg 40:541-6. 2005
    ..The aim of this report was to study the amount and distribution of immunoglobulin deposits in liver biopsies from infants with biliary atresia (BA) and correlate the results to the cytomegalovirus (CMV) infection status...
  7. doi request reprint Bile acids and coagulation factors: paradoxical association in children with chronic liver disease
    Maria Magnusson
    CLINTEC, Division of Pediatrics, Karolinska Institutet, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden
    Eur J Gastroenterol Hepatol 25:152-8. 2013
    ..To examine whether there is an association between bile acids and coagulation factors in children with chronic liver disease...
  8. doi request reprint Hepatobiliary scintigraphy during cholestatic and noncholestatic periods in patients with progressive familial intrahepatic cholestasis after partial external biliary diversion
    Henrik Arnell
    Division of Pediatrics, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Huddinge and Solna, Stockholm, Sweden
    J Pediatr Surg 46:467-72. 2011
    ....
  9. doi request reprint Occurrence and pattern of ocular disease in children with cholestatic disorders
    Kristina Teär Fahnehjelm
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Acta Ophthalmol 89:143-50. 2011
    ..To describe visual function and ocular manifestations in patients with onset of cholestasis during the neonatal period...
  10. doi request reprint Follow-up in children with progressive familial intrahepatic cholestasis after partial external biliary diversion
    Henrik Arnell
    Department of Pediatrics, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    J Pediatr Gastroenterol Nutr 51:494-9. 2010
    ....
  11. ncbi request reprint Mutation in the sterol 27-hydroxylase gene associated with fatal cholestasis in infancy
    Sara von Bahr
    Department of Clinical Chemistry, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    J Pediatr Gastroenterol Nutr 40:481-6. 2005
    ..We here present a cholestatic infant with an ongoing cytomegalovirus infection who despite intensive treatment died of severe liver disease at 4 months of age...
  12. doi request reprint The international normalized ratio according to Owren in liver disease: Interlaboratory assessment and determination of international sensitivity index
    Maria Magnusson
    CLINTEC, Karolinska Institutet, Division of Pediatrics, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden Electronic address
    Thromb Res 132:346-51. 2013
    ..Further, we determined the difference between international sensitivity index (ISI) for patients on vitamin K antagonists (ISIVKA) and ISI for patients with liver disease (ISIliver)...
  13. doi request reprint Population-based study of incidence and clinical outcome of neonatal cholestasis in patients with Down syndrome
    Henrik Arnell
    Department of Pediatric Gastroenterology, Hepatology and Nutrition, Karolinska University Hospital and Division of Pediatrics, CLINTEC, Karolinska Institutet, Stockholm, Sweden
    J Pediatr 161:899-902. 2012
    ..To study the incidence and outcome of Down syndrome-associated neonatal cholestasis in a population-based cohort...
  14. doi request reprint Tacrolimus without or with the addition of conventional immunosuppressive treatment in juvenile autoimmune hepatitis
    Joanna Ramirez Marlaka
    Västra Götalands County Council, Childrens Health Center, Västra Frölunda, Sweden
    Acta Paediatr 101:993-9. 2012
    ..Twenty patients (13 girls; age, 8-17 years; median, 13.25 years) with AIH were treated with two daily oral doses of Tac. Six of them had advanced liver disease and/or cirrhosis...
  15. ncbi request reprint Ganciclovir treatment in infants with cytomegalovirus infection and cholestasis
    Bjorn Fischler
    Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    J Pediatr Gastroenterol Nutr 34:154-7. 2002
    ..Pediatric use of the antiviral drug ganciclovir to treat patients with CMV infection has increased. In this study, infants with CMV infection and cholestasis were treated with ganciclovir...
  16. ncbi request reprint Acquired aplastic anaemia in seven children with severe hepatitis with or without liver failure
    Emma Honkaniemi
    Department of Paediatrics, Karolinska University Hospital, Huddinge, CLINTEC, Karolinska Institutet, S 141 86 Stockholm, Sweden
    Acta Paediatr 96:1660-4. 2007
    ..Several causative factors have been discussed, such as viral infections and autoimmunity. Here we describe the natural history of this condition in 7 children and investigate possible hepatitis-causing agents...
  17. doi request reprint Preoperative observations and short-term outcome after partial external biliary diversion in 13 patients with progressive familial intrahepatic cholestasis
    Henrik Arnell
    Department of Pediatrics, CLINTEC, Karolinska University Hospital, Huddinge and Solna, SE 141 86 Stockholm, Sweden
    J Pediatr Surg 43:1312-20. 2008
    ..An alternative approach is surgical diversion of bile, that is, partial external biliary diversion (PEBD). The aim of the study was to describe 13 patients with PFIC who have undergone PEBD...
  18. ncbi request reprint A population-based study on the incidence and possible pre- and perinatal etiologic risk factors of biliary atresia
    Bjorn Fischler
    Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    J Pediatr 141:217-22. 2002
    ..To study the incidence, etiologic risk factors, and outcome of biliary atresia...
  19. ncbi request reprint Cognitive and emotional outcome after pediatric liver transplantation
    Petra Adebäck
    Department of Psychology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    Pediatr Transplant 7:385-9. 2003
    ..We conclude that the high degree of cognitive and emotional problems after liver transplantation is an important argument for routine psychologic follow-up and support in these patients...
  20. ncbi request reprint Optic nerve hypoplasia in cholestatic infants: a multiple case study
    Kristina Teär Fahnehjelm
    Department of Paediatric Ophthalmology, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    Acta Ophthalmol Scand 81:130-7. 2003
    ..To present four infants with optic nerve hypoplasia and cholestasis...
  21. ncbi request reprint Recombinant FVIIa in children with liver disease
    Maria Pettersson
    Department of Paediatrics, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm S 141 86, Sweden
    Thromb Res 116:185-97. 2005
    ..The aim of this study was to investigate the clinical and biochemical effects of recombinant activated factor VII (rFVIIa) in the treatment of bleeding in children with liver disease...
  22. ncbi request reprint Vaccination of the immunocompromised child
    Thomas H Casswall
    Paediatric Gastroenterology, Hepatology and Nutrition, Children s Hospital, Karolinska University Hospital, Sweden
    Expert Rev Vaccines 4:725-38. 2005
    ..With increasing knowledge of the immunologic basis of vaccination and how immunosuppressive drugs interfere with the immune system, improved vaccines could be tailored, and adequate, individualized guidelines issued...
  23. doi request reprint Acute liver failure in a child with Epstein-Barr virus infection and undiagnosed glycerol kinase deficiency, mimicking hemophagocytic lymphohistiocytosis
    Anna Nordenstrom
    Department of Pediatrics, Karolinska University Hospital, Stockholm, Sweden
    J Pediatr Gastroenterol Nutr 47:98-101. 2008
  24. ncbi request reprint Active, fulminant, lethal myocarditis associated with parvovirus B19 infection in an infant
    Nikos Papadogiannakis
    Department of Pathology, Karolinska Institute, Huddinge University Hospital, 14186, Stockholm, Sweden
    Clin Infect Dis 35:1027-31. 2002
    ..PCR analysis should be used as a complement in suspected cases, to enhance the rate of detection of the infection and to reach a correct diagnosis...
  25. ncbi request reprint HCV infection in a child without obvious risk factors for blood-borne infections
    Bjorn Fischler
    Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    Scand J Infect Dis 34:698-9. 2002
    ..It is likely that she contracted a chronic HCV infection which was later transmitted to her daughter. A similar route of infection is suggested in other HCV-infected patients lacking obvious risk factors...