Research Topics
| Bjorn FischlerSummaryAffiliation: Karolinska University Hospital Country: Sweden Publications
| Collaborators
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Detail Information
Publications
Cholestatic liver disease in adults may be due to an inherited defect in bile acid biosynthesisB Fischler
Department of Pediatrics, Karolinska University Hospital, Huddinge, Sweden
J Intern Med 262:254-62. 2007..An increasing number of treatable inborn errors of bile acid synthesis have been described, primarily in infants with severe cholestatic liver disease...- Virus-specific T cell immune response in children and adolescents with chronic hepatitis B virus infectionBjorn Fischler
Department of Pediatrics, Karolinska University Hospital, Huddinge, Stockholm, Sweden
J Pediatr Gastroenterol Nutr 45:75-83. 2007..To study the hepatitis B-specific T cell-mediated immune response in chronically infected children and adolescents... - Living-related liver transplantation in children--a single center evaluation of the outcome of donor candidates and recipientsBjorn Fischler
Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
Pediatr Transplant 12:531-5. 2008..The fact that parents of BA patients have potential liver pathology may be of importance for the understanding of the etiology of the disease and have possible implications for the choice of donors... 
Early cytomegalovirus infection and the long-term outcome of biliary atresiaBjorn Fischler
Department of Pediatrics, Karolinska University Hospital, CLINTEC, Karolinska Intitutet, Stockholm, Sweden
Acta Paediatr 98:1600-2. 2009..To study the impact of ongoing cytomegalovirus (CMV) infection at presentation of biliary atresia (BA) on the long-term outcome after Kasai procedure...- Hepatitis C virus infectionBjorn Fischler
Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
Semin Fetal Neonatal Med 12:168-73. 2007..Treatment combinations of interferon and ribavirin seem to be at least as effective in children as in adults. However, the negative effect on growth of interferon requires specific attention by paediatricians... - Immunoglobulin deposits in liver tissue from infants with biliary atresia and the correlation to cytomegalovirus infectionBjorn Fischler
Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
J Pediatr Surg 40:541-6. 2005..The aim of this report was to study the amount and distribution of immunoglobulin deposits in liver biopsies from infants with biliary atresia (BA) and correlate the results to the cytomegalovirus (CMV) infection status... - Hepatobiliary scintigraphy during cholestatic and noncholestatic periods in patients with progressive familial intrahepatic cholestasis after partial external biliary diversionHenrik Arnell
Division of Pediatrics, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Huddinge and Solna, Stockholm, Sweden
J Pediatr Surg 46:467-72. 2011.... - Occurrence and pattern of ocular disease in children with cholestatic disordersKristina Teär Fahnehjelm
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Acta Ophthalmol 89:143-50. 2011..To describe visual function and ocular manifestations in patients with onset of cholestasis during the neonatal period... - Follow-up in children with progressive familial intrahepatic cholestasis after partial external biliary diversionHenrik Arnell
Department of Pediatrics, CLINTEC, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
J Pediatr Gastroenterol Nutr 51:494-9. 2010.... - Bile acids and coagulation factors: paradoxical association in children with chronic liver diseaseMaria Magnusson
CLINTEC, Division of Pediatrics, Karolinska Institutet, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden
Eur J Gastroenterol Hepatol 25:152-8. 2013..To examine whether there is an association between bile acids and coagulation factors in children with chronic liver disease... - Population-based study of incidence and clinical outcome of neonatal cholestasis in patients with Down syndromeHenrik Arnell
Department of Pediatric Gastroenterology, Hepatology and Nutrition, Karolinska University Hospital and Division of Pediatrics, CLINTEC, Karolinska Institutet, Stockholm, Sweden
J Pediatr 161:899-902. 2012..To study the incidence and outcome of Down syndrome-associated neonatal cholestasis in a population-based cohort... - Cognitive and emotional outcome after pediatric liver transplantationPetra Adebäck
Department of Psychology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
Pediatr Transplant 7:385-9. 2003..We conclude that the high degree of cognitive and emotional problems after liver transplantation is an important argument for routine psychologic follow-up and support in these patients... - A population-based study on the incidence and possible pre- and perinatal etiologic risk factors of biliary atresiaBjorn Fischler
Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
J Pediatr 141:217-22. 2002..To study the incidence, etiologic risk factors, and outcome of biliary atresia... - Tacrolimus without or with the addition of conventional immunosuppressive treatment in juvenile autoimmune hepatitisJoanna Ramirez Marlaka
Västra Götalands County Council, Childrens Health Center, Västra Frölunda, Sweden
Acta Paediatr 101:993-9. 2012..Twenty patients (13 girls; age, 8-17 years; median, 13.25 years) with AIH were treated with two daily oral doses of Tac. Six of them had advanced liver disease and/or cirrhosis... - Ganciclovir treatment in infants with cytomegalovirus infection and cholestasisBjorn Fischler
Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
J Pediatr Gastroenterol Nutr 34:154-7. 2002..Pediatric use of the antiviral drug ganciclovir to treat patients with CMV infection has increased. In this study, infants with CMV infection and cholestasis were treated with ganciclovir... - Acquired aplastic anaemia in seven children with severe hepatitis with or without liver failureEmma Honkaniemi
Department of Paediatrics, Karolinska University Hospital, Huddinge, CLINTEC, Karolinska Institutet, S 141 86 Stockholm, Sweden
Acta Paediatr 96:1660-4. 2007..Several causative factors have been discussed, such as viral infections and autoimmunity. Here we describe the natural history of this condition in 7 children and investigate possible hepatitis-causing agents... - Preoperative observations and short-term outcome after partial external biliary diversion in 13 patients with progressive familial intrahepatic cholestasisHenrik Arnell
Department of Pediatrics, CLINTEC, Karolinska University Hospital, Huddinge and Solna, SE 141 86 Stockholm, Sweden
J Pediatr Surg 43:1312-20. 2008..An alternative approach is surgical diversion of bile, that is, partial external biliary diversion (PEBD). The aim of the study was to describe 13 patients with PFIC who have undergone PEBD... - Optic nerve hypoplasia in cholestatic infants: a multiple case studyKristina Teär Fahnehjelm
Department of Paediatric Ophthalmology, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
Acta Ophthalmol Scand 81:130-7. 2003..To present four infants with optic nerve hypoplasia and cholestasis... - Recombinant FVIIa in children with liver diseaseMaria Pettersson
Department of Paediatrics, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm S 141 86, Sweden
Thromb Res 116:185-97. 2005..The aim of this study was to investigate the clinical and biochemical effects of recombinant activated factor VII (rFVIIa) in the treatment of bleeding in children with liver disease... - Vaccination of the immunocompromised childThomas H Casswall
Paediatric Gastroenterology, Hepatology and Nutrition, Children s Hospital, Karolinska University Hospital, Sweden
Expert Rev Vaccines 4:725-38. 2005..With increasing knowledge of the immunologic basis of vaccination and how immunosuppressive drugs interfere with the immune system, improved vaccines could be tailored, and adequate, individualized guidelines issued... - Acute liver failure in a child with Epstein-Barr virus infection and undiagnosed glycerol kinase deficiency, mimicking hemophagocytic lymphohistiocytosisAnna Nordenstrom
Department of Pediatrics, Karolinska University Hospital, Stockholm, Sweden
J Pediatr Gastroenterol Nutr 47:98-101. 2008 - Active, fulminant, lethal myocarditis associated with parvovirus B19 infection in an infantNikos Papadogiannakis
Department of Pathology, Karolinska Institute, Huddinge University Hospital, 14186, Stockholm, Sweden
Clin Infect Dis 35:1027-31. 2002..PCR analysis should be used as a complement in suspected cases, to enhance the rate of detection of the infection and to reach a correct diagnosis... - HCV infection in a child without obvious risk factors for blood-borne infectionsBjorn Fischler
Department of Pediatrics, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
Scand J Infect Dis 34:698-9. 2002..It is likely that she contracted a chronic HCV infection which was later transmitted to her daughter. A similar route of infection is suggested in other HCV-infected patients lacking obvious risk factors...