Affiliation: Karolinska Institutet
- Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndromeMichael Feyder
Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, Rockville, MD 20852 9411, USA
Am J Psychiatry 167:1508-17. 2010..PSD-95 (postsynaptic density-95, DLG4) orchestrates protein-protein interactions at excitatory synapses and is a major functional bridge interconnecting a neurexinneuroligin-SHANK pathway implicated in autism spectrum disorders...
- A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preferenceMarguerite C Camp
Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism NIH, 5625 Fishers Ln, Rockville, MD 20852 1798, USA
Addict Biol 16:428-39. 2011..These data reveal a major, novel role for PSD-95 in mediating EtOH behaviors, and add to growing evidence that PSD-95 is a key mediator of the effects of multiple abused drugs...
- Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?Paul J Fitzgerald
Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20852 9411, USA
Neurobiol Dis 40:608-21. 2010..Collectively, these findings demonstrate mania-related abnormalities in GluA1 KO and, combined with previous findings, suggest this mutant may provide a novel model of features of schizoaffective disorder...