Andreas E R Fasth

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Skewed distribution of proinflammatory CD4+CD28null T cells in rheumatoid arthritis
    Andreas E R Fasth
    Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Arthritis Res Ther 9:R87. 2007
  2. doi request reprint T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells
    Andreas E R Fasth
    Rheumatology Unit, Center for Molecular Medicine L8 04, Karolinska University Hospital, Stockholm S 171 76, Sweden
    J Immunol 183:4792-9. 2009
  3. doi request reprint Expanded T cell receptor Vβ-restricted T cells from patients with sporadic inclusion body myositis are proinflammatory and cytotoxic CD28null T cells
    Jayesh M Pandya
    Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden
    Arthritis Rheum 62:3457-66. 2010
  4. doi request reprint Activating NK-cell receptors co-stimulate CD4(+)CD28(-) T cells in patients with rheumatoid arthritis
    Andreas E R Fasth
    Rheumatology Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Eur J Immunol 40:378-87. 2010
  5. doi request reprint High mobility group box chromosomal protein 1 acts as a proliferation signal for activated T lymphocytes
    Erik Sundberg
    Department of Woman and Child Health, Pediatric Rheumatology Research Unit, Karolinska Institutet Karolinska University Hospital, L 8 04 CMM, S 17176 Stockholm, Sweden
    Immunobiology 214:303-9. 2009

Detail Information

Publications5

  1. pmc Skewed distribution of proinflammatory CD4+CD28null T cells in rheumatoid arthritis
    Andreas E R Fasth
    Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Arthritis Res Ther 9:R87. 2007
    ..Together these data imply a primary role for CD4+CD28null T cells in manifestations elsewhere than in the joints of patients with HCMV-seropositive rheumatoid arthritis...
  2. doi request reprint T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells
    Andreas E R Fasth
    Rheumatology Unit, Center for Molecular Medicine L8 04, Karolinska University Hospital, Stockholm S 171 76, Sweden
    J Immunol 183:4792-9. 2009
    ..Our observations imply that CD28(null) T cells represent clinically important effector cells in dermatomyositis and polymyositis, and that HCMV might play a role in propagating disease in a subset of patients...
  3. doi request reprint Expanded T cell receptor Vβ-restricted T cells from patients with sporadic inclusion body myositis are proinflammatory and cytotoxic CD28null T cells
    Jayesh M Pandya
    Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden
    Arthritis Rheum 62:3457-66. 2010
    ..This study was undertaken to investigate the phenotype and functionality of T cells, specifically a subset of proinflammatory, cytotoxic, and apoptosis-resistant T cells defined as CD28(null) T cells, in the pathogenesis of sporadic IBM...
  4. doi request reprint Activating NK-cell receptors co-stimulate CD4(+)CD28(-) T cells in patients with rheumatoid arthritis
    Andreas E R Fasth
    Rheumatology Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Eur J Immunol 40:378-87. 2010
    ..This may have consequences for the inflammatory responses imposed by these cells, thus influencing disease manifestations...
  5. doi request reprint High mobility group box chromosomal protein 1 acts as a proliferation signal for activated T lymphocytes
    Erik Sundberg
    Department of Woman and Child Health, Pediatric Rheumatology Research Unit, Karolinska Institutet Karolinska University Hospital, L 8 04 CMM, S 17176 Stockholm, Sweden
    Immunobiology 214:303-9. 2009
    ..0 microg/ml. HMGB1 had no effect on proliferation in the absence of anti-CD3 stimulation or during T-cell activation obtained using high doses of anti-CD3 mAb. Our results demonstrate a direct HMGB1-mediated effect in adaptive immunity...