Anna Farnert

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre study
    A Farnert
    Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Huddinge University Hospital, 14186 Huddinge, Sweden
    Trans R Soc Trop Med Hyg 95:225-32. 2001
  2. ncbi Polyclonal Plasmodium falciparum malaria in travelers and selection of antifolate mutations after proguanil prophylaxis
    Anna Farnert
    Department of Medicine, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Am J Trop Med Hyg 66:487-91. 2002
  3. pmc Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports
    Anna Farnert
    Department of Medicine, Division of Infectious Diseases, Karolinska Institute, Karolinska Hospital, S 171 76 Stockholm, Sweden
    BMJ 326:628-9. 2003
  4. ncbi Limited advantage of multiple consecutive samples for genotyping Plasmodium falciparum populations during the first days of treatment
    Anna Farnert
    Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Am J Trop Med Hyg 73:204-6. 2005
  5. ncbi Influence of consecutive-day blood sampling on polymerase chain reaction-adjusted parasitological cure rates in an antimalarial-drug trial conducted in Tanzania
    Andreas Martensson
    Infectious Diseases Unit, Department of Medicine, Karolinska University Hospital, Stockholm 17176, Sweden
    J Infect Dis 195:597-601. 2007
  6. pmc Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania
    Anna Farnert
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    Malar J 11:176. 2012
  7. pmc Optimization and validation of multi-coloured capillary electrophoresis for genotyping of Plasmodium falciparum merozoite surface proteins (msp1 and 2)
    Anne Liljander
    Department of Medicine Solna, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Malar J 8:78. 2009
  8. pmc Extensive dynamics of Plasmodium falciparum densities, stages and genotyping profiles
    Anna Farnert
    Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Malar J 7:241. 2008
  9. ncbi Multiclonal asymptomatic Plasmodium falciparum infections predict a reduced risk of malaria disease in a Tanzanian population
    Sandor Bereczky
    Infectious Diseases Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital Solna, 17176 Stockholm, Sweden
    Microbes Infect 9:103-10. 2007
  10. pmc Influences of intermittent preventive treatment and persistent multiclonal Plasmodium falciparum infections on clinical malaria risk
    Anne Liljander
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 5:e13649. 2010

Detail Information

Publications23

  1. ncbi Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre study
    A Farnert
    Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Huddinge University Hospital, 14186 Huddinge, Sweden
    Trans R Soc Trop Med Hyg 95:225-32. 2001
    ..falciparum but this study has revealed limitations in comparing results on multiplicity of infection derived from different laboratories and emphasizes the need for highly standardized laboratory protocols...
  2. ncbi Polyclonal Plasmodium falciparum malaria in travelers and selection of antifolate mutations after proguanil prophylaxis
    Anna Farnert
    Department of Medicine, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Am J Trop Med Hyg 66:487-91. 2002
    ..Chemoprophylaxis reduces the number of infecting clones and selects for resistant parasites as shown for proguanil through mutations in the dhfr gene...
  3. pmc Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports
    Anna Farnert
    Department of Medicine, Division of Infectious Diseases, Karolinska Institute, Karolinska Hospital, S 171 76 Stockholm, Sweden
    BMJ 326:628-9. 2003
  4. ncbi Limited advantage of multiple consecutive samples for genotyping Plasmodium falciparum populations during the first days of treatment
    Anna Farnert
    Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Am J Trop Med Hyg 73:204-6. 2005
    ..The genotypes detected in one pre-treatment sample thus appear to reflect the parasite subpopulations of the clinical malaria infection during the following days, and additional sampling does not provide any additional information...
  5. ncbi Influence of consecutive-day blood sampling on polymerase chain reaction-adjusted parasitological cure rates in an antimalarial-drug trial conducted in Tanzania
    Andreas Martensson
    Infectious Diseases Unit, Department of Medicine, Karolinska University Hospital, Stockholm 17176, Sweden
    J Infect Dis 195:597-601. 2007
    ..Interpretation of PCR-adjusted results will significantly depend on methodology...
  6. pmc Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania
    Anna Farnert
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    Malar J 11:176. 2012
    ..Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment...
  7. pmc Optimization and validation of multi-coloured capillary electrophoresis for genotyping of Plasmodium falciparum merozoite surface proteins (msp1 and 2)
    Anne Liljander
    Department of Medicine Solna, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Malar J 8:78. 2009
    ..falciparum msp1 and msp2 has been adapted to the CE technique. The protocol and optimization process as well as the potentials and limitations of the technique in molecular epidemiology studies and anti-malarial drug trials are reported...
  8. pmc Extensive dynamics of Plasmodium falciparum densities, stages and genotyping profiles
    Anna Farnert
    Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Malar J 7:241. 2008
    ..The aim of this study was to assess the dynamics of asymptomatic P. falciparum infections in a few hours intervals...
  9. ncbi Multiclonal asymptomatic Plasmodium falciparum infections predict a reduced risk of malaria disease in a Tanzanian population
    Sandor Bereczky
    Infectious Diseases Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital Solna, 17176 Stockholm, Sweden
    Microbes Infect 9:103-10. 2007
    ....
  10. pmc Influences of intermittent preventive treatment and persistent multiclonal Plasmodium falciparum infections on clinical malaria risk
    Anne Liljander
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 5:e13649. 2010
    ..We have investigated how seasonal IPT affects the genetic diversity of Plasmodium falciparum infections and the risk of subsequent clinical malaria...
  11. doi Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in Africa
    Sabina Dahlström
    Malaria Research, Karolinska Institutet, Stockholm, Sweden
    J Infect Dis 200:1456-64. 2009
    ..Our data suggest for the first time, to our knowledge, the involvement of pfMRP1 in P. falciparum in vivo response to ACT...
  12. pmc Plasmodium falciparum infection patterns since birth and risk of severe malaria: a nested case-control study in children on the coast of Kenya
    Klara Lundblom
    Unit of Infectious Diseases, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 8:e56032. 2013
    ..These findings provide important insights on the immunity to severe disease, knowledge essential for the development of a vaccine against severe malaria...
  13. pmc Transmission-dependent tolerance to multiclonal Plasmodium falciparum infection
    Anna Farnert
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    J Infect Dis 200:1166-75. 2009
    ..falciparum infections...
  14. ncbi Short report: Rapid DNA extraction from archive blood spots on filter paper for genotyping of Plasmodium falciparum
    Sandor Bereczky
    Infectious Diseases Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Am J Trop Med Hyg 72:249-51. 2005
    ..This rapid, simple, and inexpensive extraction method generated superior results from archived specimens compared with the two standard methods and may represent a useful tool in molecular epidemiologic studies...
  15. pmc Breadth of anti-merozoite antibody responses is associated with the genetic diversity of asymptomatic Plasmodium falciparum infections and protection against clinical malaria
    Josea Rono
    Infectious Diseases Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden
    Clin Infect Dis 57:1409-16. 2013
    ..We assessed the breadth of antibody responses to several vaccine candidate merozoite antigens in relation to the infecting parasite population and clinical immunity...
  16. pmc Bacterial coinfections in travelers with malaria: rationale for antibiotic therapy
    Johanna Sandlund
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    J Clin Microbiol 51:15-21. 2013
    ..The study supports a restrictive antibiotic policy in returning travelers with malaria...
  17. pmc Plasmodium falciparum line-dependent association of in vitro growth-inhibitory activity and risk of malaria
    Josea Rono
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    Infect Immun 80:1900-8. 2012
    ..Our study contributes knowledge on the biological importance of growth inhibition and the potential influence of P. falciparum erythrocyte invasion phenotypic differences on its relationship to protective immunity against malaria...
  18. pmc High-speed shaking of frozen blood clots for extraction of human and malaria parasite DNA
    Klara Lundblom
    Infectious Diseases Unit, Karolinska Institutet, Center for Molecular Medicine, L8 01, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Malar J 10:229. 2011
    ..Frozen blood clots remaining after serum collection is an often disregarded source of host and pathogen DNA due to troublesome handling and suboptimal outcome...
  19. pmc Clearance of asymptomatic P. falciparum Infections Interacts with the number of clones to predict the risk of subsequent malaria in Kenyan children
    Anne Liljander
    Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 6:e16940. 2011
    ..Asymptomatic multiclonal P. falciparum infections are common and may predict host protection. Here, we have investigated the effect of clearing asymptomatic infections on the risk of clinical malaria...
  20. doi Plasmodium falciparum population dynamics: only snapshots in time?
    Anna Farnert
    Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, SE 17176 Stockholm, Sweden
    Trends Parasitol 24:340-4. 2008
    ..falciparum infections have practical implications on the design and interpretation of malaria studies. Most assessments will, indeed, only provide snapshots of the parasite population dynamics...
  21. pmc High affinity antibodies to Plasmodium falciparum merozoite antigens are associated with protection from malaria
    Sreenivasulu B Reddy
    Department of Microbiology, Tumor and Cell Biology MTC, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e32242. 2012
    ..Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown...
  22. pmc Respiratory viruses in hospitalized children with influenza-like illness during the H1n1 2009 pandemic in Sweden
    Samuel Rhedin
    Department of Medicine Solna Infectious Diseases Unit, Karolinska University Hospital, Stockholm, Sweden
    PLoS ONE 7:e51491. 2012
    ..The human rhinovirus (HRV) has been suggested to have delayed the pandemic through viral interference. The importance of co-infections over time during the pandemic and in terms of severity of the disease needs to be assessed...
  23. ncbi Elevated anti-malarial IgE in asymptomatic individuals is associated with reduced risk for subsequent clinical malaria
    Sandor Bereczky
    Infectious Diseases Unit, Karolinska University Hospital, Karolinska Institutet, S 171 76 Stockholm, Sweden
    Int J Parasitol 34:935-42. 2004
    ..Specific IgE antibodies may play role in maintaining anti-malarial immunity, or indicate other aspects of immune function relevant for protection against malaria...