Affiliation: Karolinska Institutet
Bartesaghi L, Wang Y, Fontanet P, Wanderoy S, Berger F, Wu H, et al
. PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis. Cell Rep. 2019;26:3484-3492.e4 pubmed publisher
..Our results thus demonstrate that PRDM12 is necessary for the generation of the entire lineage of pain-initiating neurons. ..
Cipriani S, Phan V, Medard J, Horvath R, Lochmuller H, Chrast R, et al
. Neuromuscular Junction Changes in a Mouse Model of Charcot-Marie-Tooth Disease Type 4C. Int J Mol Sci. 2018;19: pubmed publisher
..Together these observations suggest that CMT4C pathology includes a compromised NMJ even in the absence of changes to the innervating axon. ..
DomÃ¨nech EstÃ©vez E, Baloui H, Repond C, Rosafio K, MÃ©dard J, Tricaud N, et al
. Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination. J Neurosci. 2015;35:4151-6 pubmed publisher
..These data indicate that lactate homeostasis participates in the regulation of the SC myelination program and reveal that similar to CNS, PNS axon-glial metabolic interactions are most likely mediated by MCTs. ..