Guojun Cheng

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Isoflavone treatment for acute menopausal symptoms
    Guojun Cheng
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden
    Menopause 14:468-73. 2007
  2. ncbi request reprint Differential regulation of estrogen receptor (ER)alpha and ERbeta in primate mammary gland
    Guojun Cheng
    Department of Medical Nutrition, Karolinska Institute, Novum, S14186, Huddinge, Sweden
    J Clin Endocrinol Metab 90:435-44. 2005
  3. doi request reprint Effects of short-term estradiol and norethindrone acetate treatment on the breasts of normal postmenopausal women
    Guojun Cheng
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Sweden
    Menopause 20:496-503. 2013
  4. pmc Ovarian wedge resection restores fertility in estrogen receptor beta knockout (ERbeta-/-) mice
    Jose Inzunza
    Division of Medical Nutrition, Department of Biosciences and Nutrition, Karolinska University Hospital, Karolinska Institutet, Novum, S 141 86 Stockholm, Sweden
    Proc Natl Acad Sci U S A 104:600-5. 2007
  5. pmc Estrogen receptors ER alpha and ER beta in proliferation in the rodent mammary gland
    Guojun Cheng
    Department of Medical Nutrition, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    Proc Natl Acad Sci U S A 101:3739-46. 2004
  6. ncbi request reprint Estrogen receptors: how do they signal and what are their targets
    Nina Heldring
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    Physiol Rev 87:905-31. 2007
  7. pmc Gonadotropin-positive pituitary tumors accompanied by ovarian tumors in aging female ERbeta-/- mice
    Xiaotang Fan
    Division of Medical Nutrition, Department of Biosciences and Nutrition, Karolinska Institute, Novum 141 86, Sweden
    Proc Natl Acad Sci U S A 107:6453-8. 2010
  8. ncbi request reprint Analysis of estrogen receptor expression in tissues
    Margaret Warner
    Karolinska Institute, Huddinge University Hospital, Novum, Huddinge, S 14186, Sweden
    Methods Enzymol 364:448-63. 2003
  9. pmc Regulation of postnatal lung development and homeostasis by estrogen receptor beta
    Cesare Patrone
    Department of Medical Nutrition, Karolinska Institute, Novum, Huddinge University Hospital, SE14186 Huddinge, Sweden
    Mol Cell Biol 23:8542-52. 2003
  10. ncbi request reprint Update on estrogen signaling
    Zhang Weihua
    Department of Medical Nutrition, Department of Biosciences, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    FEBS Lett 546:17-24. 2003

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Isoflavone treatment for acute menopausal symptoms
    Guojun Cheng
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden
    Menopause 14:468-73. 2007
    ..The aim of present study was to evaluate the effects of isoflavone treatment in postmenopausal women...
  2. ncbi request reprint Differential regulation of estrogen receptor (ER)alpha and ERbeta in primate mammary gland
    Guojun Cheng
    Department of Medical Nutrition, Karolinska Institute, Novum, S14186, Huddinge, Sweden
    J Clin Endocrinol Metab 90:435-44. 2005
    ..As selective receptor ligands become available, they will be helpful in delineation of the functions of these receptors...
  3. doi request reprint Effects of short-term estradiol and norethindrone acetate treatment on the breasts of normal postmenopausal women
    Guojun Cheng
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Sweden
    Menopause 20:496-503. 2013
    ....
  4. pmc Ovarian wedge resection restores fertility in estrogen receptor beta knockout (ERbeta-/-) mice
    Jose Inzunza
    Division of Medical Nutrition, Department of Biosciences and Nutrition, Karolinska University Hospital, Karolinska Institutet, Novum, S 141 86 Stockholm, Sweden
    Proc Natl Acad Sci U S A 104:600-5. 2007
    ..The follicles do not mature because of insufficient blood supply. This problem is overcome by stimulating neovascularization by simple wedge resection of the ovaries...
  5. pmc Estrogen receptors ER alpha and ER beta in proliferation in the rodent mammary gland
    Guojun Cheng
    Department of Medical Nutrition, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    Proc Natl Acad Sci U S A 101:3739-46. 2004
    ..ER beta facilitates the return of ER alpha to the nucleus and restores responsiveness to E(2). By down-regulating ER beta, tamoxifen may prolong refractoriness to E(2) in mammary epithelium...
  6. ncbi request reprint Estrogen receptors: how do they signal and what are their targets
    Nina Heldring
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    Physiol Rev 87:905-31. 2007
    ..In this review we focus on several of the interesting recent discoveries concerning estrogen receptors, on estrogen as a morphogen, and on the molecular mechanisms of anti-estrogen signaling...
  7. pmc Gonadotropin-positive pituitary tumors accompanied by ovarian tumors in aging female ERbeta-/- mice
    Xiaotang Fan
    Division of Medical Nutrition, Department of Biosciences and Nutrition, Karolinska Institute, Novum 141 86, Sweden
    Proc Natl Acad Sci U S A 107:6453-8. 2010
    ..The absence of tumors in the ERalphabeta(-/-) mice suggests that tumor development requires the presence of ERalpha...
  8. ncbi request reprint Analysis of estrogen receptor expression in tissues
    Margaret Warner
    Karolinska Institute, Huddinge University Hospital, Novum, Huddinge, S 14186, Sweden
    Methods Enzymol 364:448-63. 2003
  9. pmc Regulation of postnatal lung development and homeostasis by estrogen receptor beta
    Cesare Patrone
    Department of Medical Nutrition, Karolinska Institute, Novum, Huddinge University Hospital, SE14186 Huddinge, Sweden
    Mol Cell Biol 23:8542-52. 2003
    ..These results provide a potential molecular mechanism for the gender differences in alveolar structure observed in the adult lung and establish ERbeta as a previously unknown regulator of postnatal lung development and homeostasis...
  10. ncbi request reprint Update on estrogen signaling
    Zhang Weihua
    Department of Medical Nutrition, Department of Biosciences, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    FEBS Lett 546:17-24. 2003
    ..The use of ERbeta-specific ligands against certain forms of cancer represents one of the many pharmaceutical possibilities that have been created thanks to the discovery of ERbeta...
  11. pmc A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia
    Paloma Alonso-Magdalena
    Department of Biosciences and Nutrition, Karolinska Institute, Novum, SE 141 86 Huddinge, Sweden
    Proc Natl Acad Sci U S A 106:2859-63. 2009
    ..TGF-beta is thought to play a key role in EMT. Our data suggests that TGF-beta/Smad should be considered as targets for treatment of BPH...
  12. ncbi request reprint Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells
    Chunyan Zhao
    Department of Biosciences and Nutrition, Novum, Karolinska Institutet, Huddinge, Sweden
    Cancer Res 67:3955-62. 2007
    ..Our data suggest that ERbeta2 could influence ERalpha-mediated effects relevant for breast cancer development, including hormone responsiveness...
  13. ncbi request reprint A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary
    Guojun Cheng
    Department of Medical Nutrition, Karolinska Institute, Novum, S 14186 Huddinge, Sweden
    Biol Reprod 66:77-84. 2002
    ....