Alberto Cagigi

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Cytotoxic T-lymphocytes secrete soluble factors that induce caspase-mediated apoptosis in glioblastoma cell lines
    Alberto Cagigi
    Department of Laboratory Medicine, Division of Clinical Immunology, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Neuroimmunol 225:34-42. 2010
  2. pmc CD27(-) B-cells produce class switched and somatically hyper-mutated antibodies during chronic HIV-1 infection
    Alberto Cagigi
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 4:e5427. 2009
  3. ncbi The impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children
    Alberto Cagigi
    Department of Laboratory Medicine, Division of Clinical Immunology, Karolinska University Hospital Huddinge, Stockholm, Sweden
    AIDS 24:2075-80. 2010
  4. doi Relation of activation-induced deaminase (AID) expression with antibody response to A(H1N1)pdm09 vaccination in HIV-1 infected patients
    Alberto Cagigi
    Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden
    Vaccine 31:2231-7. 2013
  5. doi Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection
    Alberto Cagigi
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    Blood 112:4401-10. 2008
  6. pmc Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children
    Simone Pensieroso
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm 171 77, Sweden
    Proc Natl Acad Sci U S A 106:7939-44. 2009
  7. ncbi B cell immunopathology during HIV-1 infection: lessons to learn for HIV-1 vaccine design
    Alberto Cagigi
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Nobels vag 16, S 17177 Stockholm, Sweden
    Vaccine 26:3016-25. 2008
  8. ncbi Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy
    Alberto Cagigi
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Lancet Infect Dis 10:499-503. 2010
  9. pmc Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection
    Barbro Ehlin-Henriksson
    Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    Immunology 127:549-57. 2009
  10. doi Kinetics of antibody and memory B cell responses after MMR immunization in children and young adults
    Maria Kakoulidou
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden
    Vaccine 31:711-7. 2013

Collaborators

Detail Information

Publications12

  1. ncbi Cytotoxic T-lymphocytes secrete soluble factors that induce caspase-mediated apoptosis in glioblastoma cell lines
    Alberto Cagigi
    Department of Laboratory Medicine, Division of Clinical Immunology, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Neuroimmunol 225:34-42. 2010
    ..High steady-state levels of Bcl-2 were identified as potentially accounting for the resistance of a proportion of glioblastoma lines to factors secreted by activated CTLs...
  2. pmc CD27(-) B-cells produce class switched and somatically hyper-mutated antibodies during chronic HIV-1 infection
    Alberto Cagigi
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 4:e5427. 2009
    ..Our data add important information for the understanding of the mechanisms underlying the loss of specific antibody production observed during HIV-1 infection...
  3. ncbi The impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children
    Alberto Cagigi
    Department of Laboratory Medicine, Division of Clinical Immunology, Karolinska University Hospital Huddinge, Stockholm, Sweden
    AIDS 24:2075-80. 2010
    ..We also aimed at characterizing the level of expression of CXCR4, CXCR5 and CCR7 on immature-transitional B-cells, as these receptors are important mediators for homing of B-cells...
  4. doi Relation of activation-induced deaminase (AID) expression with antibody response to A(H1N1)pdm09 vaccination in HIV-1 infected patients
    Alberto Cagigi
    Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden
    Vaccine 31:2231-7. 2013
    ..Assessing AID expression before vaccination may be an additional useful tool for defining a vaccination strategy in immune-compromised individuals at risk of immunization failure...
  5. doi Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection
    Alberto Cagigi
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    Blood 112:4401-10. 2008
    ..Our findings indicate that altered expression of the chemokine receptor-ligand pair, CXCR5/CXCL13, may participate in the establishment of B-cell dysfunctions during HIV-1 infection...
  6. pmc Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children
    Simone Pensieroso
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm 171 77, Sweden
    Proc Natl Acad Sci U S A 106:7939-44. 2009
    ..Timing of HAART initiation is the major factor predicting the longevity of B cell responses in vaccinated HIV-1-infected children...
  7. ncbi B cell immunopathology during HIV-1 infection: lessons to learn for HIV-1 vaccine design
    Alberto Cagigi
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Nobels vag 16, S 17177 Stockholm, Sweden
    Vaccine 26:3016-25. 2008
    ..In addition novel data indicate that B cell activation may be at the basis of impaired immune responses...
  8. ncbi Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy
    Alberto Cagigi
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Lancet Infect Dis 10:499-503. 2010
    ..By maintaining B-cell responses, highly active antiretroviral therapy might improve the efficacy of influenza vaccines in individuals with HIV...
  9. pmc Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection
    Barbro Ehlin-Henriksson
    Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    Immunology 127:549-57. 2009
    ..Both receptors mediate homing to mucosal tissue. The alterations of the expression of these molecules may lead to retention of EBV-infected tonsillar B cells in the interfollicular region of the tonsil...
  10. doi Kinetics of antibody and memory B cell responses after MMR immunization in children and young adults
    Maria Kakoulidou
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden
    Vaccine 31:711-7. 2013
    ..It remains to be shown if memory B-cells provide the same protection as specific antibodies, but our data is a valuable complement to the incomplete knowledge about correlates of protection after vaccination...
  11. ncbi Chemokine CXCL12 enhances proliferation in pre-B-ALL via STAT5 activation
    Frida Mowafi
    Microbiology Tumour Biology Center, Karolinska Institutet, Stockholm, Sweden
    Pediatr Blood Cancer 50:812-7. 2008
    ....
  12. ncbi Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection
    Kehmia Titanji
    Microbiology and Tumor Biology Center, Karolinska Institutet, S 17177 Stockholm, Sweden
    Blood 108:1580-7. 2006
    ..This may have important consequences for the response of HIV-infected patients to immunizations...