Thomas R Burglin

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome
    Yongtao Xue-Franzén
    Clinical Research Center, Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden
    BMC Genomics 14:479. 2013
  2. pmc Genome-wide characterisation of the Gcn5 histone acetyltransferase in budding yeast during stress adaptation reveals evolutionarily conserved and diverged roles
    Yongtao Xue-Franzén
    School of Life Sciences, Södertörn University, Huddinge, SE 141 89, Sweden
    BMC Genomics 11:200. 2010
  3. doi request reprint Homeodomain subtypes and functional diversity
    Thomas R Burglin
    Department of Biosciences and Nutrition, and Center for Biosciences, Karolinska Institutet, Hälsovägen 7, Novum, SE 141 83, Huddinge, Sweden
    Subcell Biochem 52:95-122. 2011
  4. pmc The Hedgehog protein family
    Thomas R Burglin
    Department of Biosciences and Nutrition, Karolinska Institutet, and School of Life Sciences, Södertörn University, Hälsovägen 7, SE 141 57 Huddinge, Sweden
    Genome Biol 9:241. 2008
  5. doi request reprint Conditions for dye-filling of sensory neurons in Caenorhabditis elegans
    Yong Guang Tong
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    J Neurosci Methods 188:58-61. 2010
  6. pmc Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development
    Ivana Bratic
    Department of Laboratory Medicine, Division of Metabolic Diseases, Novum, Karolinska Institutet, Stockholm SE 141 86, Sweden
    Nucleic Acids Res 37:1817-28. 2009
  7. doi request reprint Spatio-temporal reference model of Caenorhabditis elegans embryogenesis with cell contact maps
    Jûrgen Hench
    Department of Biosciences and Nutrition, Karolinska Institutet, and School of Life Sciences, Södertörn University, Hälsovägen 7, Huddinge 141 57, Sweden
    Dev Biol 333:1-13. 2009
  8. pmc Comprehensive analysis of gene expression patterns of hedgehog-related genes
    Limin Hao
    Department of Biosciences and Nutrition, and Center for Genomics and Bioinformatics, Karolinska Institutet, SE 141 57 Huddinge, Sweden
    BMC Genomics 7:280. 2006
  9. ncbi request reprint The hedgehog-related gene qua-1 is required for molting in Caenorhabditis elegans
    Limin Hao
    Department of Biosciences and Nutrition, and Center for Genomics and Bioinformatics, Karolinska Institutet, Huddinge, Sweden
    Dev Dyn 235:1469-81. 2006
  10. ncbi request reprint The hedgehog-related gene wrt-5 is essential for hypodermal development in Caenorhabditis elegans
    Limin Hao
    Department of Biosciences at Novum, and Center for Genomics and Bioinformatics, Karolinska Institutet, Hälsovägen 7, SE 141 57 Huddinge, Sweden
    Dev Biol 290:323-36. 2006

Collaborators

  • M Labouesse
  • Yong Guang Tong
  • Limin Hao
  • Yongtao Xue-Franzén
  • Johan Henriksson
  • Jûrgen Hench
  • Anthony P H Wright
  • Ivana Bratic
  • David Baillie
  • Anna Johnsson
  • David Brodin
  • Aleksandra Trifunovic
  • Martin Lüppert
  • Adam Antebi
  • Samuel Liegeois
  • Krishanu Mukherjee
  • Robert Johnsen
  • Gudrun Aspöck
  • Gilbert Lauter

Detail Information

Publications10

  1. pmc Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome
    Yongtao Xue-Franzén
    Clinical Research Center, Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden
    BMC Genomics 14:479. 2013
    ..Gcn5 plays several different roles in gene transcription throughout the genome but their characterisation by classical mutation approaches is hampered by the high degree of apparent functional redundancy between HAT proteins...
  2. pmc Genome-wide characterisation of the Gcn5 histone acetyltransferase in budding yeast during stress adaptation reveals evolutionarily conserved and diverged roles
    Yongtao Xue-Franzén
    School of Life Sciences, Södertörn University, Huddinge, SE 141 89, Sweden
    BMC Genomics 11:200. 2010
    ..cerevisiae and S. pombe, which can be studied under similar environmental conditions, provides an opportunity to examine the interface between conserved regulatory components and their cellular applications in different organisms...
  3. doi request reprint Homeodomain subtypes and functional diversity
    Thomas R Burglin
    Department of Biosciences and Nutrition, and Center for Biosciences, Karolinska Institutet, Hälsovägen 7, Novum, SE 141 83, Huddinge, Sweden
    Subcell Biochem 52:95-122. 2011
    ..Many other types of homeodomain proteins play roles in the determination of cell fates and cell differentiation. Homeobox genes thus perform key roles for all aspects of the development of an organism...
  4. pmc The Hedgehog protein family
    Thomas R Burglin
    Department of Biosciences and Nutrition, Karolinska Institutet, and School of Life Sciences, Södertörn University, Hälsovägen 7, SE 141 57 Huddinge, Sweden
    Genome Biol 9:241. 2008
    ..The resulting signaling cascade converges on the transcription factor Cubitus interruptus (Ci), or its mammalian counterparts, the Gli proteins, which activate or repress target genes...
  5. doi request reprint Conditions for dye-filling of sensory neurons in Caenorhabditis elegans
    Yong Guang Tong
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    J Neurosci Methods 188:58-61. 2010
    ..An additional benefit is that it can also stain the excretory duct. The method allows genetic screens to be performed to identify mutants that selectively affect only one of the sensory structures or the excretory duct...
  6. pmc Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development
    Ivana Bratic
    Department of Laboratory Medicine, Division of Metabolic Diseases, Novum, Karolinska Institutet, Stockholm SE 141 86, Sweden
    Nucleic Acids Res 37:1817-28. 2009
    ..elegans even in the absence of the mitochondrial replicase...
  7. doi request reprint Spatio-temporal reference model of Caenorhabditis elegans embryogenesis with cell contact maps
    Jûrgen Hench
    Department of Biosciences and Nutrition, Karolinska Institutet, and School of Life Sciences, Södertörn University, Hälsovägen 7, Huddinge 141 57, Sweden
    Dev Biol 333:1-13. 2009
    ..To visualize the 4D model interactively we developed a software utility. Our model provides an anatomical resource and can serve as foundation to display 4D expression data, a basis for developmental systems biology...
  8. pmc Comprehensive analysis of gene expression patterns of hedgehog-related genes
    Limin Hao
    Department of Biosciences and Nutrition, and Center for Genomics and Bioinformatics, Karolinska Institutet, SE 141 57 Huddinge, Sweden
    BMC Genomics 7:280. 2006
    ..Previously, the expression pattern of seventeen genes was examined, which showed that they are primarily expressed in the ectoderm...
  9. ncbi request reprint The hedgehog-related gene qua-1 is required for molting in Caenorhabditis elegans
    Limin Hao
    Department of Biosciences and Nutrition, and Center for Genomics and Bioinformatics, Karolinska Institutet, Huddinge, Sweden
    Dev Dyn 235:1469-81. 2006
    ..Our results suggest that both the Hint/Hog domain and Qua domain are critically required for the function of QUA-1...
  10. ncbi request reprint The hedgehog-related gene wrt-5 is essential for hypodermal development in Caenorhabditis elegans
    Limin Hao
    Department of Biosciences at Novum, and Center for Genomics and Bioinformatics, Karolinska Institutet, Hälsovägen 7, SE 141 57 Huddinge, Sweden
    Dev Biol 290:323-36. 2006
    ..In conclusion, we show that wrt-5 is an essential gene that - despite its lack of a Hint domain - has multiple functions in C. elegans and is implicated in cell shape integrity...