S Bruce

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes
    Albin Sandelin
    Center for Genomics and Bioinformatics, Karolinska Institutet, Stockholm, Sweden
    BMC Genomics 5:99. 2004
  2. pmc Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression
    Karin Richter
    Umeå Center for Molecular Medicin, Umea Universitet, 90187 Umea, Sweden
    BMC Genomics 7:75. 2006
  3. doi request reprint Restriction site-specific methylation studies of imprinted genes with quantitative real-time PCR
    Sara Bruce
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    Clin Chem 54:491-9. 2008
  4. doi request reprint The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms
    S Bruce
    Department of Biosciences and Nutrition, Halsovagen 7 9, 14157 Huddinge, Sweden
    J Med Genet 46:159-67. 2009
  5. pmc Global analysis of uniparental disomy using high density genotyping arrays
    S Bruce
    Department of Biosciences at Novum, Karolinska Institutet, Huddinge, Sweden
    J Med Genet 42:847-51. 2005
  6. doi request reprint Clinically distinct epigenetic subgroups in Silver-Russell syndrome: the degree of H19 hypomethylation associates with phenotype severity and genital and skeletal anomalies
    Sara Bruce
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    J Clin Endocrinol Metab 94:579-87. 2009

Collaborators

  • R Leinonen
  • J Kere
  • F Nyberg
  • M Wickman
  • J Riedler
  • Karin Richter
  • Albin Sandelin
  • Lina Dahl
  • Leif Carlsson
  • Valtteri Wirta
  • Cecilia Williams
  • Joakim Lundeberg
  • Johan Ericson
  • Pär G Engström
  • Boris Lenhard
  • Wyeth W Wasserman
  • Peter Bailey
  • Joanna M Klos

Detail Information

Publications6

  1. pmc Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes
    Albin Sandelin
    Center for Genomics and Bioinformatics, Karolinska Institutet, Stockholm, Sweden
    BMC Genomics 5:99. 2004
    ..Here, we focus on UCRs that cluster around genes involved in early vertebrate development; genes conserved over 450 million years of vertebrate evolution...
  2. pmc Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression
    Karin Richter
    Umeå Center for Molecular Medicin, Umea Universitet, 90187 Umea, Sweden
    BMC Genomics 7:75. 2006
    ..These cell lines efficiently down-regulate Lhx2 expression upon dox withdrawal leading to a rapid differentiation into various myeloid cell types...
  3. doi request reprint Restriction site-specific methylation studies of imprinted genes with quantitative real-time PCR
    Sara Bruce
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    Clin Chem 54:491-9. 2008
    ..Quick and accurate quantification of methylation at such genes can be of appreciable diagnostic aid...
  4. doi request reprint The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms
    S Bruce
    Department of Biosciences and Nutrition, Halsovagen 7 9, 14157 Huddinge, Sweden
    J Med Genet 46:159-67. 2009
    ..Little is known about the asthma candidate gene neuropeptide S receptor 1 (NPSR1) in relation to environmental exposures, but recent evidences suggest its role as an effect modifier...
  5. pmc Global analysis of uniparental disomy using high density genotyping arrays
    S Bruce
    Department of Biosciences at Novum, Karolinska Institutet, Huddinge, Sweden
    J Med Genet 42:847-51. 2005
    ..Detection of UPD has largely been performed through labour intensive screening of DNA from patients and their parents, using microsatellite markers...
  6. doi request reprint Clinically distinct epigenetic subgroups in Silver-Russell syndrome: the degree of H19 hypomethylation associates with phenotype severity and genital and skeletal anomalies
    Sara Bruce
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    J Clin Endocrinol Metab 94:579-87. 2009
    ..The H19 imprinting control region (ICR), located on chromosome 11p15.5, has been reported hypomethylated in 20-65% of Silver-Russell syndrome (SRS) patients...