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Species | C BrobergerSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Publications
Hypothalamic neurohistochemistry of the murine anorexia (anx/anx) mutation: altered processing of neuropeptide Y in the arcuate nucleusC Broberger
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Comp Neurol 387:124-35. 1997..These data suggest that a defect in neuropeptide Y-ergic signalling in the arcuate neurons may contribute to the failure to thrive in anx/anx mice...
Brain regulation of food intake and appetite: molecules and networksC Broberger
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
J Intern Med 258:301-27. 2005..Finally, recent findings on the genetics of human obesity are summarized, as well as the potential for novel treatments of body weight disorders...
Hypothalamic and vagal neuropeptide circuitries regulating food intakeC Broberger
Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden
Physiol Behav 74:669-82. 2001..Disturbances in the hypothalamic neuropeptide systems have been implicated in the phenotype of a genetic model of fatal hypophagia, the mouse anorexia (anx) mutation, which is also discussed...
Expression and regulation of cholecystokinin and cholecystokinin receptors in rat nodose and dorsal root gangliaC Broberger
Department of Neuroscience, Berzelius Vag 1, Karolinska Institutet, 171 77 Stockholm, Sweden
Brain Res 903:128-40. 2001..The stimulation of CCK and CCK(B)-R gene expression following vagotomy suggests a possible involvement in the response to injury for these molecules...
Differential effects of intrastriatally infused fully and endcap phosphorothioate antisense oligonucleotides on morphology, histochemistry and prodynorphin expression in rat brainC Broberger
Department of Neuroscience, Karolinska Institutet, S 171 77, Stockholm, Sweden
Brain Res Mol Brain Res 75:25-45. 2000....
Hypothalamic cocaine- and amphetamine-regulated transcript (CART) neurons: histochemical relationship to thyrotropin-releasing hormone, melanin-concentrating hormone, orexin/hypocretin and neuropeptide YC Broberger
Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden
Brain Res 848:101-13. 1999....
Neuropeptide Y innervation and neuropeptide-Y-Y1-receptor-expressing neurons in the paraventricular hypothalamic nucleus of the mouseC Broberger
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Neuroendocrinology 70:295-305. 1999..This study further defines the link between NPY-induced feeding and the hypothalamus-pituitary-thyroid axis...
Cocaine- and amphetamine-regulated transcript in the rat vagus nerve: A putative mediator of cholecystokinin-induced satietyC Broberger
Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
Proc Natl Acad Sci U S A 96:13506-11. 1999....
Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleusC Broberger
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Neuroendocrinology 66:393-408. 1997..Release of NPY, and possible coexisting messengers, may be controlled by presynaptic Y2-R expressed in NPY neurons. Taken together, the findings support the division of Y1-Rs and Y2-Rs into post- and presynaptic receptors, respectively...
Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide Y and agouti gene-related protein systemsC Broberger
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Comp Neurol 402:460-74. 1998..Furthermore, the results implicate hypocretin/orexin and melanin-concentrating hormone-expressing cells as downstream targets in neuropeptide Y-induced feeding...
Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamusV Sergeyev
Department of Neuroscience, Karolinska Institutet, S-171 77, Stockholm, Sweden
Brain Res Mol Brain Res 90:93-100. 2001....
Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous systemT Hokfelt
Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
Brain Res Brain Res Rev 26:154-66. 1998..It is possible that these changes in NPY-ergic mechanisms may underlie some of the central symptoms associated with the prion disease. (ABSTRACT TRUNCATED)..
Changes in neuropeptide Y receptors and pro-opiomelanocortin in the anorexia (anx/anx) mouse hypothalamusC Broberger
Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
J Neurosci 19:7130-9. 1999..The present data suggest that degeneration of the arcuate POMC system is a feature characteristic of the anx/anx mouse. The possible relationship to the NPYergic phenotype of this animal is discussed...
CCK-ergic mechanisms in sensory systemsT Hokfelt
Department of Neuroscience, Retzius Laboratory, Karolinska Institutet, Stockholm, Sweden
Scand J Clin Lab Invest Suppl 234:69-74. 2001..In man and monkey the CCK1 receptor seems important in the dorsal horn under normal conditions, indicating distinct species differences...
The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated miceC Broberger
Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
Proc Natl Acad Sci U S A 95:15043-8. 1998..Our results show that arcuate NPY neurons, identified by the presence of AGRP, project more extensively in the brain than previously known and indicate that the feeding regulatory actions of NPY may extend beyond the hypothalamus...
Galanin and NPY, two peptides with multiple putative roles in the nervous systemT Hokfelt
Dept of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Horm Metab Res 31:330-4. 1999..It may therefore be interesting to analyse to what extent drugs affecting galaninergic transmission also may be efficient in the treatment of, for example, depression...
Neuropeptides--an overviewT Hokfelt
Department of Neuroscience, Karolinska Institutet, S 171 77, Stockholm, Sweden
Neuropharmacology 39:1337-56. 2000..Taken together it seems that peptides may play a role particularly when the nervous system is stressed, challenged or afflicted by disease, and that peptidergic systems may, therefore, be targets for novel therapeutic strategies...
Potent and nontoxic antisense oligonucleotides containing locked nucleic acidsC Wahlestedt
Center for Genomics Research and Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
Proc Natl Acad Sci U S A 97:5633-8. 2000..LNA-containing oligonucleotides will likely be useful for many antisense applications...
Distribution and neuropeptide coexistence of nucleobindin-2 mRNA/nesfatin-like immunoreactivity in the rat CNSK S Foo
Department of Neuroscience, Karolinska Institutet, Retzius v 8, 17177 Stockholm, Sweden
Neuroscience 156:563-79. 2008..In addition, the subcellular distribution of nesfatin-like immunoreactivity indicates that this protein may not be processed like a conventional secreted neuromodulator...
Glial-cell-line-derived neurotrophic factor induces nerve fibre formation in primary cultures of adrenal chromaffin cellsP Förander
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Cell Tissue Res 305:43-51. 2001....
