A M Bennet

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Decreased risk for myocardial infarction and lower tumor necrosis factor-alpha levels in carriers of variants of the PDCD1 gene
    Anna M Bennet
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Hum Immunol 67:700-5. 2006
  2. ncbi request reprint Association of TNF-alpha serum levels and TNFA promoter polymorphisms with risk of myocardial infarction
    A M Bennet
    Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Box 210, S 171 77 Stockholm, Sweden
    Atherosclerosis 187:408-14. 2006
  3. ncbi request reprint Bioinformatic and experimental tools for identification of single-nucleotide polymorphisms in genes with a potential role for the development of the insulin resistance syndrome
    A M Bennet
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    J Intern Med 249:127-36. 2001
  4. ncbi request reprint Gene expression of inflammatory mediators in different chambers of the human heart
    G Valen
    Department of Thoracic Surgery, Center for Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Ann Thorac Surg 70:562-7. 2000
  5. ncbi request reprint Phenotype selection for detecting variable genes: a survey of cardiovascular quantitative traits and TNF locus polymorphism
    Mun Gwan Hong
    Department of Cell and Molecular Biology, Karolinska Institute, Berzelius vag 35, 171 77 Stockholm, Sweden
    Eur J Hum Genet 15:685-93. 2007
  6. ncbi request reprint A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity
    Hagit Katzov
    Center for Genomics and Bioinformatics, Karolinska Institute, Berzelius väg 35 171 77, Stockholm, Sweden
    Hum Mol Genet 13:2647-57. 2004
  7. ncbi request reprint Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction
    Kristina Edfeldt
    Experimental Cardiovascular Research Unit, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
    Eur Heart J 25:1447-53. 2004
  8. ncbi request reprint Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction
    Anna M Bennet
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, P O Box 210, S 171 77, Stockholm, Sweden
    Atherosclerosis 171:359-67. 2003
  9. ncbi request reprint Alcohol and long-term prognosis after a first acute myocardial infarction: the SHEEP study
    Imre Janszky
    Department of Public Health Sciences, Karolinska Institutet, Norrbacka, 6th Floor, Karolinska University Hospital SE 171 76 Stockholm, Sweden
    Eur Heart J 29:45-53. 2008
  10. ncbi request reprint Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction
    Umit Yasar
    Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden
    Pharmacogenetics 13:715-20. 2003

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Decreased risk for myocardial infarction and lower tumor necrosis factor-alpha levels in carriers of variants of the PDCD1 gene
    Anna M Bennet
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Hum Immunol 67:700-5. 2006
    ..Carriers of variants of the PDCD1 gene exhibit a decreased risk for nonfatal myocardial infarction, and PDCD1 mediates variation in TNF-alpha levels...
  2. ncbi request reprint Association of TNF-alpha serum levels and TNFA promoter polymorphisms with risk of myocardial infarction
    A M Bennet
    Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Box 210, S 171 77 Stockholm, Sweden
    Atherosclerosis 187:408-14. 2006
    ..Obese subjects with elevated TNF-a levels, and carriers of polymorphisms in or near TNFA are particularly susceptible to the hazards of smoking, results which may have implications for cardiovascular preventive measures...
  3. ncbi request reprint Bioinformatic and experimental tools for identification of single-nucleotide polymorphisms in genes with a potential role for the development of the insulin resistance syndrome
    A M Bennet
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    J Intern Med 249:127-36. 2001
    ..Genes with a possible role for the development of the insulin resistance syndrome (IRS) were scanned for novel single-nucleotide polymorphisms (SNPs) using bioinformatics...
  4. ncbi request reprint Gene expression of inflammatory mediators in different chambers of the human heart
    G Valen
    Department of Thoracic Surgery, Center for Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
    Ann Thorac Surg 70:562-7. 2000
    ..Inflammatory genes may be unevenly expressed in different heart chambers...
  5. ncbi request reprint Phenotype selection for detecting variable genes: a survey of cardiovascular quantitative traits and TNF locus polymorphism
    Mun Gwan Hong
    Department of Cell and Molecular Biology, Karolinska Institute, Berzelius vag 35, 171 77 Stockholm, Sweden
    Eur J Hum Genet 15:685-93. 2007
    ..Further, a case is highlighted where association between sequence variation in a gene and its product is not readily apparent even in large samples, but where association with a down-stream pathway may be...
  6. ncbi request reprint A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity
    Hagit Katzov
    Center for Genomics and Bioinformatics, Karolinska Institute, Berzelius väg 35 171 77, Stockholm, Sweden
    Hum Mol Genet 13:2647-57. 2004
    ....
  7. ncbi request reprint Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction
    Kristina Edfeldt
    Experimental Cardiovascular Research Unit, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
    Eur Heart J 25:1447-53. 2004
    ..Recent studies imply that TLR4 polymorphisms might affect atherogenesis. In this study we investigated the impact of LPS-hypo-responsive TLR4 variants on the risk of myocardial infarction (MI)...
  8. ncbi request reprint Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction
    Anna M Bennet
    Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institute, P O Box 210, S 171 77, Stockholm, Sweden
    Atherosclerosis 171:359-67. 2003
    ..Interleukin-6 (IL-6) is a key pro-inflammatory and immune-stimulatory cytokine of presumed importance for CVD and the metabolic syndrome...
  9. ncbi request reprint Alcohol and long-term prognosis after a first acute myocardial infarction: the SHEEP study
    Imre Janszky
    Department of Public Health Sciences, Karolinska Institutet, Norrbacka, 6th Floor, Karolinska University Hospital SE 171 76 Stockholm, Sweden
    Eur Heart J 29:45-53. 2008
    ..Few studies have investigated the relation between alcohol consumption, former drinking, and prognosis after an acute myocardial infarction (AMI), particularly for non-fatal outcomes...
  10. ncbi request reprint Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction
    Umit Yasar
    Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden
    Pharmacogenetics 13:715-20. 2003
    ..Possession of rare genetic variants of the CYP2C8 and CYP2C9 genes in females is associated with a modest increase in risk of AMI. This might be related to genetic differences in the formation of endogenous vasoregulating eicosanoids...
  11. ncbi request reprint Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility
    Xiaosong Wang
    The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA
    Nat Genet 37:365-72. 2005
    ..05) in individuals with myocardial infarction than in controls. We therefore conclude that Tnfsf4 underlies Ath1 in mice and that polymorphisms in its human homolog TNFSF4 increase the risk of myocardial infarction in humans...
  12. ncbi request reprint Haplotypes extending across ACE are associated with Alzheimer's disease
    Patrick G Kehoe
    Department of Care of the Elderly, University of Bristol, The John James Building, Frenchay Hospital, Bristol, UK
    Hum Mol Genet 12:859-67. 2003
    ..Results support a model whereby decreased ACE activity may influence AD susceptibility by a mechanism involving beta-amyloid metabolism...
  13. ncbi request reprint The risk of myocardial infarction is enhanced by a synergistic interaction between serum insulin and smoking
    Anna M Bennet
    Division of Cardiovascular Epidemiology, Karolinska Institute, Stockholm, Sweden
    Eur J Endocrinol 147:641-7. 2002
    ....
  14. ncbi request reprint Association of apolipoprotein E genotypes with lipid levels and coronary risk
    Anna M Bennet
    Department of Public Health and Primary Care, University of Cambridge, Cambridge, England
    JAMA 298:1300-11. 2007
    ..Previous reviews of associations of apolipoprotein E (apoE) genotype and coronary disease have been dominated by smaller studies that are liable to biases...