Research Topics
| J AsklingSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Is history of squamous-cell skin cancer a marker of poor prognosis in patients with cancer?J Askling
Karolinska Institute, Stockholm, Sweden
Ann Intern Med 131:655-9. 1999..Nonmelanoma skin cancer is associated with increased occurrence of subsequent cancer and death from cancer, but it is not known whether a history of skin cancer is associated with poor prognosis after a second diagnosis of cancer...- Increased risk for cancer following sarcoidosisJ Askling
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Am J Respir Crit Care Med 160:1668-72. 1999..4; 95% CI 0.8 to 2.2). Thus, sarcoidosis appears to be associated with a significantly increased risk for cancer in affected organs. Chronic inflammation is a putative mediator of this risk... 
Risk of non-Hodgkin's lymphoma following tuberculosisJ Askling
Department of Medical Epidemiology, Karolinska Institute, Box 281, Stockholm, S 171 77, Sweden
Br J Cancer 84:113-5. 2001..The overall relative risk was moderately increased, largely accounted for by high risks following severe tuberculosis diagnosed a long time ago...- Colorectal cancer rates among first-degree relatives of patients with inflammatory bowel disease: a population-based cohort studyJ Askling
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Lancet 357:262-6. 2001..We aimed to assess cancer rates among first-degree relatives of patients with IBD to try to determine whether an association between the two diseases exists... - Family history as a risk factor for colorectal cancer in inflammatory bowel diseaseJ Askling
Department of Medical Epidemiology, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
Gastroenterology 120:1356-62. 2001..Little is known about the cancer risk in familial inflammatory bowel disease (IBD). We assessed the significance of familial CRC, or IBD, on the risk for CRC in patients with IBD... - Haematopoietic malignancies in rheumatoid arthritis: lymphoma risk and characteristics after exposure to tumour necrosis factor antagonistsJ Askling
Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital, Stockholm, Sweden
Ann Rheum Dis 64:1414-20. 2005..Patients with rheumatoid arthritis (RA) are at increased risk of malignant lymphomas, and maybe also of leukaemia and multiple myeloma. The effect of tumour necrosis factor (TNF) antagonists on lymphoma risk and characteristics is unclear... 
Anti-tumour necrosis factor therapy in rheumatoid arthritis and risk of malignant lymphomas: relative risks and time trends in the Swedish Biologics RegisterJ Askling
Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet at Karolinska University Hospital, Stockholm, Sweden
Ann Rheum Dis 68:648-53. 2009....- Generalisability of clinical registers used for drug safety and comparative effectiveness research: coverage of the Swedish Biologics RegisterM Neovius
Department of Medicine, Karolinska Institutet, SE 171 76 Stockholm, Sweden
Ann Rheum Dis 70:516-9. 2011..To determine coverage and generalisability of data in the Swedish Biologics Register ARTIS... - Sick leave and disability pension before and after initiation of antirheumatic therapies in clinical practiceM Neovius
Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Ann Rheum Dis 70:1407-14. 2011..To investigate sick leave and disability pension in rheumatoid arthritis (RA) in relation to the initiation of biological and non-biological antirheumatic therapies in clinical practice... - Impact of parental history on patients' cardiovascular mortality in rheumatoid arthritisL Björnådal
Rheumatology Unit, Department of Medicine, Karolinska University Hospital Solna, and Karolinska Institutet, Stockholm, Sweden
Ann Rheum Dis 65:741-5. 2006..However, little is known about whether or to what extent hereditary factors for CVD contribute additional risk in patients with rheumatoid arthritis... - Swedish registers to examine drug safety and clinical issues in RAJ Askling
Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden
Ann Rheum Dis 65:707-12. 2006..The approach described is a possible prototype for long term surveillance systems needed for the safe introduction of new treatments... - Risk of ischaemic heart disease and cardiomyopathy in patients with haemochromatosis and in their first-degree relatives: a nationwide, population-based studyM Elmberg
Division of Gastroenterology and Hepatology, Karolinska University Hospital Clinical, Stockholm, Sweden
J Intern Med 272:45-54. 2012..Little is known of these risks among heterozygotes also being first-degree relatives (FDRs), thus sharing other factors for phenotypic expression of GH... - Risk for malignant lymphoma in ankylosing spondylitis: a nationwide Swedish case-control studyJ Askling
Department of Medicine, Clinical Epidemiology Unit M9 01, Karolinska University Hospital Solna, SE 171 77, Stockholm, Sweden
Ann Rheum Dis 65:1184-7. 2006..Besides inflammation-lymphoma aetiology, information on risk of lymphoma in ankylosing spondylitis is particularly important as a benchmark in the evaluation of, for example, tumour necrosis factor inhibitors... - Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphomaK E Smedby
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
Gut 54:54-9. 2005..A systematic risk assessment of more prevalent lymphoma entities, such as B cell and non-intestinal lymphomas, in coeliac disease has not been performed... - Small-area variations in sales of TNF inhibitors in Sweden between 2000 and 2009M Neovius
Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm
Scand J Rheumatol 40:8-15. 2011..To measure small-area variations in sales per capita of tumour necrosis factor (TNF) inhibitors... - Juvenile idiopathic arthritis and risk of cancer: a nationwide cohort studyJ F Simard
Karolinska Institutet, Stockholm, Sweden
Arthritis Rheum 62:3776-82. 2010..Therefore, the aim of this study was to determine the risk of cancer in patients with JIA as compared with that in the general population... - Autoimmune and inflammatory disorders and risk of malignant lymphomas--an updateK E Smedby
Department of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, Stockholm, Sweden
J Intern Med 264:514-27. 2008..Future studies of high-risk patient subsets using detailed assessments of autoimmunity/inflammation and lymphoma may give important clues to lymphomagenesis... - Rapid increase in myocardial infarction risk following diagnosis of rheumatoid arthritis amongst patients diagnosed between 1995 and 2006M E Holmqvist
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
J Intern Med 268:578-85. 2010..Few studies have included contemporary patients with RA. We recently reported that the risk of IHD is not elevated before the onset of RA symptoms. However, when, in relation to RA diagnosis, the risk is increased is unknown... - Perinatal characteristics, early life infections and later risk of rheumatoid arthritis and juvenile idiopathic arthritisC Carlens
Department of Medicine, Karolinska University Hospital and Institute, Stockholm, Sweden
Ann Rheum Dis 68:1159-64. 2009..To investigate the importance of birth characteristics and early life infections on the risk of later rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA)... - Rheumatoid arthritis registries in SwedenR F van Vollenhoven
Rheumatology Unit, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden
Clin Exp Rheumatol 23:S195-200. 2005..Data obtained from analyses based on these registries are reviewed. It is concluded that rheumatology registries are excellent tools for improving our knowledge base regarding rheumatic diseases... - The risk of malignancies in RA patients treated with biologicsJ Askling
Clinical Epidemiology Unit T2 01, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital Solna, 171 76, Stockholm, Schweden
Z Rheumatol 69:774-9. 2010..So far, but with exceptions both in terms of risks observed and absence of data, the emerging picture is reassuring rather than alarming... - Changing pattern of paediatric inflammatory bowel disease in northern Stockholm 1990-2001H Hildebrand
Department of Women and Child Health, Astrid Lindgren Children s Hospital, Stockholm, Sweden
Gut 52:1432-4. 2003..An increased incidence of paediatric Crohn's disease was reported recently by our group... - Risks of solid cancers in patients with rheumatoid arthritis and after treatment with tumour necrosis factor antagonistsJ Askling
Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital, Stockholm, Sweden
Ann Rheum Dis 64:1421-6. 2005..Existing studies of solid cancers in rheumatoid arthritis (RA) reflect cancer morbidity up until the early 1990s in prevalent cohorts admitted to hospital during the 1980s...