Björn Anderstam

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. doi request reprint Modification of the oxidative stress biomarker AOPP assay: application in uremic samples
    Björn Anderstam
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Clin Chim Acta 393:114-8. 2008
  2. doi request reprint Differences in acute metabolism of fructose between hemodialysis patients and healthy subjects
    Björn Anderstam
    Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Scand J Clin Lab Invest 73:154-60. 2013
  3. ncbi request reprint Hyperhomocysteinemia in relation to plasma free amino acids, biomarkers of inflammation and mortality in patients with chronic kidney disease starting dialysis therapy
    Mohamed E Suliman
    Department of Clinical Science, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Am J Kidney Dis 44:455-65. 2004
  4. ncbi request reprint Influence of nutritional status on plasma and erythrocyte sulphur amino acids, sulph-hydryls, and inorganic sulphate in end-stage renal disease
    Mohamed E Suliman
    Division of Baxter Novum, Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    Nephrol Dial Transplant 17:1050-6. 2002
  5. ncbi request reprint Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy
    Mohammed E Suliman
    Division of Renal Medicine and Baxter Novum, Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    J Am Soc Nephrol 14:1614-22. 2003
  6. ncbi request reprint Inflammation contributes to low plasma amino acid concentrations in patients with chronic kidney disease
    Mohammed E Suliman
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Am J Clin Nutr 82:342-9. 2005
  7. doi request reprint Circulating vascular endothelial growth factor (VEGF) and its soluble receptor 1 (sVEGFR-1) are associated with inflammation and mortality in incident dialysis patients
    Jiangzi Yuan
    Renal Medicine and Baxter Novum, Karolinska Institutet, Stockholm, Sweden
    Nephrol Dial Transplant 28:2356-63. 2013
  8. doi request reprint Clinical importance of an elevated circulating chemerin level in incident dialysis patients
    Tae Yamamoto
    Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden
    Nephrol Dial Transplant 25:4017-23. 2010
  9. doi request reprint Visfatin is increased in chronic kidney disease patients with poor appetite and correlates negatively with fasting serum amino acids and triglyceride levels
    Juan J Carrero
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Nephrol Dial Transplant 25:901-6. 2010
  10. ncbi request reprint Elevated serum 8-oxo-dG in hemodialysis patients: a marker of systemic inflammation?
    Siamak Haghdoost
    Department of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden
    Antioxid Redox Signal 8:2169-73. 2006

Collaborators

Detail Information

Publications30

  1. doi request reprint Modification of the oxidative stress biomarker AOPP assay: application in uremic samples
    Björn Anderstam
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Clin Chim Acta 393:114-8. 2008
    ..We therefore developed and tested a modified version of the AOPP assay to minimize the impact of this interference...
  2. doi request reprint Differences in acute metabolism of fructose between hemodialysis patients and healthy subjects
    Björn Anderstam
    Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Scand J Clin Lab Invest 73:154-60. 2013
    ..In conclusion, a glucose and fat rich meal is associated with delayed absorption and/or metabolism of fructose in HD patients as well as increased serum uric acid levels...
  3. ncbi request reprint Hyperhomocysteinemia in relation to plasma free amino acids, biomarkers of inflammation and mortality in patients with chronic kidney disease starting dialysis therapy
    Mohamed E Suliman
    Department of Clinical Science, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Am J Kidney Dis 44:455-65. 2004
    ..Plasma levels of total homocysteine (tHcy) and free amino acids (AAs) are influenced by nutritional status in patients with chronic kidney disease (CKD), whereas the role of chronic inflammation is not clear...
  4. ncbi request reprint Influence of nutritional status on plasma and erythrocyte sulphur amino acids, sulph-hydryls, and inorganic sulphate in end-stage renal disease
    Mohamed E Suliman
    Division of Baxter Novum, Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    Nephrol Dial Transplant 17:1050-6. 2002
    ....
  5. ncbi request reprint Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy
    Mohammed E Suliman
    Division of Renal Medicine and Baxter Novum, Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    J Am Soc Nephrol 14:1614-22. 2003
    ..However, in this small cohort, the plasma pentosidine content did not predict outcome. Thus, accumulation of plasma pentosidine is unlikely to be an appropriate clinically useful marker to predict mortality in ESRD patients...
  6. ncbi request reprint Inflammation contributes to low plasma amino acid concentrations in patients with chronic kidney disease
    Mohammed E Suliman
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Am J Clin Nutr 82:342-9. 2005
    ..Inflammation and malnutrition are common in chronic kidney disease (CKD) patients, and plasma concentrations of free amino acids (AAs) in these patients are often abnormal. Malnutrition contributes to alterations in AA concentrations...
  7. doi request reprint Circulating vascular endothelial growth factor (VEGF) and its soluble receptor 1 (sVEGFR-1) are associated with inflammation and mortality in incident dialysis patients
    Jiangzi Yuan
    Renal Medicine and Baxter Novum, Karolinska Institutet, Stockholm, Sweden
    Nephrol Dial Transplant 28:2356-63. 2013
    ..We investigated determinants of VEGF and sVEGFR-1 as well as their relationship with all-cause mortality in incident dialysis patients...
  8. doi request reprint Clinical importance of an elevated circulating chemerin level in incident dialysis patients
    Tae Yamamoto
    Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden
    Nephrol Dial Transplant 25:4017-23. 2010
    ..We explored possible links between chemerin and various clinical, nutritional and biochemical markers as well as its association with 5-year all-cause mortality...
  9. doi request reprint Visfatin is increased in chronic kidney disease patients with poor appetite and correlates negatively with fasting serum amino acids and triglyceride levels
    Juan J Carrero
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Nephrol Dial Transplant 25:901-6. 2010
    ..We hypothesized that increased visfatin levels in CKD patients may be involved in the regulation of appetite and nutrient homeostasis...
  10. ncbi request reprint Elevated serum 8-oxo-dG in hemodialysis patients: a marker of systemic inflammation?
    Siamak Haghdoost
    Department of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden
    Antioxid Redox Signal 8:2169-73. 2006
    ..Serum levels of 8-oxo-dG, in combination with other inflammatory markers, serve as useful diagnostic tools for identification of patients in risk for inflammatory complications...
  11. ncbi request reprint Plasma reduced homocysteine and other aminothiol concentrations in patients with CKD
    Bodil Sjöberg
    Division of Renal Medicine, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Am J Kidney Dis 47:60-71. 2006
    ..This study is designed to examine the relation between different forms of Hcy and other aminothiols in hemodialysis (HD) patients, peritoneal dialysis (PD) patients, and nondialyzed patients with CKD...
  12. pmc Circulating follistatin in patients with chronic kidney disease: implications for muscle strength, bone mineral density, inflammation, and survival
    Tetsu Miyamoto
    Division of Baxter Novum, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden
    Clin J Am Soc Nephrol 6:1001-8. 2011
    ..Follistatin mediates muscle growth and bone mineralization. At present, it is unknown whether circulating follistatin levels are altered in chronic kidney disease (CKD) or links to CKD risk factors and outcomes...
  13. doi request reprint Elevated serum levels of S-adenosylhomocysteine, but not homocysteine, are associated with cardiovascular disease in stage 5 chronic kidney disease patients
    Alessandro Valli
    Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Clin Chim Acta 395:106-10. 2008
    ..Although, S-adenosylhomocysteine (SAH) levels have been linked to CVD in non-renal populations, such relationship has not been evaluated in CKD...
  14. ncbi request reprint Rate of synthetic oligosaccharide degradation as a novel measure of amylase activity in peritoneal dialysis patients
    Elvia Garcia-Lopez
    Divisions of Baxter Novum and Renal Medicine, Karolinska Institutet, Stockholm, Sweden
    Perit Dial Int 28:296-304. 2008
    ..We studied the rate by which an exogenous oligosaccharide (maltoheptaose; G7) is degraded ex vivo by amylase in plasma from PD patients treated with glucose or icodextrin PD solutions...
  15. ncbi request reprint Heat sterilization of peritoneal dialysis solutions influences ingestive behavior in non-uremic rats
    Zhi Hua Zheng
    Divisions of Baxter Novum and Renal Medicine, Karolinska Institutet, K 56 Huddinge University Hospital, S 14186 Huddinge, Stockholm, Sweden
    Kidney Int 62:1447-53. 2002
    ..This was studied in an experimental appetite model in rat...
  16. ncbi request reprint Hyperhomocysteinemia and its relationship to cardiovascular disease in ESRD: influence of hypoalbuminemia, malnutrition, inflammation, and diabetes mellitus
    Mohamed E Suliman
    Division of Baxter Novum, Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
    Am J Kidney Dis 41:S89-95. 2003
    ..However, it is obvious that hypoalbuminemia is of interest because a substantial fraction of tHcy (>70%) is protein bound, mainly to albumin...
  17. ncbi request reprint Determination of high and low molecular weight molecules of icodextrin in plasma and dialysate, using gel filtration chromatography, in peritoneal dialysis patients
    Elvia Garcia-Lopez
    Department of Clinical Science, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Perit Dial Int 25:181-91. 2005
    ....
  18. ncbi request reprint Enhanced RAGE-mediated NFkappaB stimulation in inflamed hemodialysis patients
    Ernesto Rodríguez-Ayala
    Division of Renal Medicine, Department of Clinical Science, Karolinska Institutet, K56, Karolinska University Hospital at Huddinge, 141 86 Stockholm, Sweden
    Atherosclerosis 180:333-40. 2005
    ..Inflammation and oxidative stress biomarkers are interrelated in ESRD. Inflammatory cell signal pathways, such as NFkappaB, are activated by CML-modification of proteins via RAGE...
  19. doi request reprint Pentraxin 3, a sensitive early marker of hemodialysis-induced inflammation
    Bodil Sjöberg
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Blood Purif 34:290-7. 2012
    ..The purpose of this investigation was to determine if the long pentraxin 3 (PTX-3) may be a useful marker of intradialytic inflammation since it is rapidly released in the vasculature...
  20. pmc Effect of circulating soluble receptor for advanced glycation end products (sRAGE) and the proinflammatory RAGE ligand (EN-RAGE, S100A12) on mortality in hemodialysis patients
    Ayumu Nakashima
    Division of Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Clin J Am Soc Nephrol 5:2213-9. 2010
    ..Whether alterations at this level contribute to the increased mortality observed in patients on dialysis is currently unknown...
  21. ncbi request reprint Vascular calcification inhibitors in relation to cardiovascular disease with special emphasis on fetuin-A in chronic kidney disease
    Mohamed E Suliman
    Department of Clinical Science, Intervention and Technology, Divisions of Renal Medicine and Baxter Novum, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden
    Adv Clin Chem 46:217-62. 2008
    ..Recent experimental and clinical studies also suggest an intriguing link between fetuin-A, insulin resistance, and the metabolic syndrome...
  22. pmc Metabolic changes in summer active and anuric hibernating free-ranging brown bears (Ursus arctos)
    Peter Stenvinkel
    Division of Renal Medicine, Department of Clinical Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e72934. 2013
    ..Further studies to understand how bears can prevent the development of uremia despite minimal renal function during hibernation could provide new therapeutic avenues for the treatment of human kidney disease. ..
  23. doi request reprint Changes in circulating biomarkers during a single hemodialysis session
    Tae Yamamoto
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Stockholm, Sweden
    Hemodial Int 17:59-66. 2013
    ..VC-related markers were in general not affected by the single HD session; however, the observed correlation between acute changes of FGF-23 and phosphate during HD warrants further studies...
  24. ncbi request reprint Associations of VEGF and its receptors sVEGFR-1 and -2 with cardiovascular disease and survival in prevalent haemodialysis patients
    Qunying Guo
    1Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Nephrol Dial Transplant 24:3468-73. 2009
    ..Soluble VEGF receptors (sVEGFR)-1 and -2 are circulating endogenous modulators of VEGF activity. We thus studied the relationship between sVEGFR-1 and -2 and survival in a cohort of prevalent haemodialysis (HD) patients...
  25. ncbi request reprint Plasma pentraxin 3 in patients with chronic kidney disease: associations with renal function, protein-energy wasting, cardiovascular disease, and mortality
    Mengli Tong
    Division of Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Clin J Am Soc Nephrol 2:889-97. 2007
    ..Plasma protein pentraxin 3 concentrations are elevated in a wide range of diseased states. However, no study has evaluated protein pentraxin 3 in patients with chronic kidney disease...
  26. ncbi request reprint Overestimation of advanced oxidation protein products in uremic plasma due to presence of triglycerides and other endogenous factors
    Alessandro Valli
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden
    Clin Chim Acta 379:87-94. 2007
    ..Advanced oxidation protein products (AOPP), a suggested protein biomarker of oxidative stress, are elevated in patients with chronic kidney disease (CKD), who also often suffer from hypertriglyceridemia...
  27. ncbi request reprint Effect of bicarbonate on muscle protein in patients receiving hemodialysis
    Erland Löfberg
    Department of Clinical Science, Intervention, and Technology, Division of Renal Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Am J Kidney Dis 48:419-29. 2006
    ..Metabolic acidosis stimulates whole-body net protein breakdown in healthy adults and patients with kidney failure, but few studies investigated how acidosis affects protein metabolism in individual tissues, such as skeletal muscle...
  28. pmc Macrophage migration inhibitory factor (MIF) and thyroid hormone alterations in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)
    Mårten Wendt
    Department of Renal Medicine, Karolinska University Hospital, Department of Clinical Sciences, Intervention and Technology, Karolinska Institute, Stockholm, Sweden
    Mol Med 19:109-14. 2013
    ..Further studies could reveal whether the association between AAV and thyroid hormone levels in the context of elevated MIF may present a link as well as a target of treatment...
  29. doi request reprint Associations between amino acids and bone mineral density in men with idiopathic osteoporosis
    Ylva Pernow
    Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden
    Bone 47:959-65. 2010
    ..The correlations between tryptophan and bone mineral density and bone histomorphometry suggest a link between tryptophan and osteoblast function which may be important for bone health...
  30. ncbi request reprint Icodextrin metabolism and alpha-amylase activity in nonuremic rats undergoing chronic peritoneal dialysis
    Elvia Garcia-Lopez
    Divisions of Baxter Novum and Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden
    Perit Dial Int 27:415-23. 2007
    ..To study the metabolism of icodextrin and alpha-amylase activity following daily exposure to dialysis solutions containing either glucose or icodextrin as osmotic agent in rats...