Olof Akre

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Maternal and gestational risk factors for hypospadias
    Olof Akre
    Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital, Stockholm, Sweden
    Environ Health Perspect 116:1071-6. 2008
  2. doi request reprint Risk of contralateral testicular cancer among men with unilaterally undescended testis: a meta analysis
    Olof Akre
    Cancer Epidemiology Unit, CeRMS and CPO Piemonte, University of Turin, Turin 10126, Italy
    Int J Cancer 124:687-9. 2009
  3. doi request reprint Does a testicular dysgenesis syndrome exist?
    Olof Akre
    Cancer Epidemiology Unit, CeRMS and CPO Piemonte, University of Turin, Turin, Italy
    Hum Reprod 24:2053-60. 2009
  4. doi request reprint Mortality among men with locally advanced prostate cancer managed with noncurative intent: a nationwide study in PCBaSe Sweden
    Olof Akre
    Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 60:554-63. 2011
  5. pmc Perinatal risk factors for diabetes in later life
    Magnus Kaijser
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Diabetes 58:523-6. 2009
  6. ncbi request reprint Birth order, sibship size, and risk for germ-cell testicular cancer
    Lorenzo Richiardi
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Epidemiology 15:323-9. 2004
  7. ncbi request reprint Women smoking and testicular cancer: one epidemic causing another?
    Andreas Pettersson
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 109:941-4. 2004
  8. ncbi request reprint Age at surgery for undescended testis and risk of testicular cancer
    Andreas Pettersson
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    N Engl J Med 356:1835-41. 2007
  9. pmc Cancer risk in mothers of men operated for undescended testis
    Hadriano M Lacerda
    Cancer Epidemiology Unit, CPO and CeRMS, University of Turin, Italy
    PLoS ONE 5:e14285. 2010
  10. ncbi request reprint Preterm birth, low birth weight, and risk for esophageal adenocarcinoma
    Magnus Kaijser
    Clinical Epidemiology Unit, Department of Medicine at Karolinska Hospital, Stockholm, Sweden
    Gastroenterology 128:607-9. 2005

Detail Information

Publications46

  1. pmc Maternal and gestational risk factors for hypospadias
    Olof Akre
    Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital, Stockholm, Sweden
    Environ Health Perspect 116:1071-6. 2008
    ..An increase in the prevalence of hypospadias has been reported, but the environmental causes remain virtually unknown...
  2. doi request reprint Risk of contralateral testicular cancer among men with unilaterally undescended testis: a meta analysis
    Olof Akre
    Cancer Epidemiology Unit, CeRMS and CPO Piemonte, University of Turin, Turin 10126, Italy
    Int J Cancer 124:687-9. 2009
    ..30 to 9.31) and 1.74 (95% CI, 1.01 to 2.98), respectively. We conclude that in 1-sided undescended testis, the risk of testicular cancer may be increased in both testes, although to a much greater extent on the ipsilateral side...
  3. doi request reprint Does a testicular dysgenesis syndrome exist?
    Olof Akre
    Cancer Epidemiology Unit, CeRMS and CPO Piemonte, University of Turin, Turin, Italy
    Hum Reprod 24:2053-60. 2009
    ..There is furthermore little evidence of shared causes between the alleged components of the syndrome...
  4. doi request reprint Mortality among men with locally advanced prostate cancer managed with noncurative intent: a nationwide study in PCBaSe Sweden
    Olof Akre
    Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 60:554-63. 2011
    ..There are limited prognostic data for locally advanced prostate cancer PCa to guide in the choice of treatment...
  5. pmc Perinatal risk factors for diabetes in later life
    Magnus Kaijser
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Diabetes 58:523-6. 2009
    ..We therefore investigated the significance of these two factors separately...
  6. ncbi request reprint Birth order, sibship size, and risk for germ-cell testicular cancer
    Lorenzo Richiardi
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Epidemiology 15:323-9. 2004
    ..Several studies have reported an inverse association between birth order and testicular cancer risk, but estimates vary greatly and the biologic mechanism underlying the association is not established...
  7. ncbi request reprint Women smoking and testicular cancer: one epidemic causing another?
    Andreas Pettersson
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 109:941-4. 2004
    ....
  8. ncbi request reprint Age at surgery for undescended testis and risk of testicular cancer
    Andreas Pettersson
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    N Engl J Med 356:1835-41. 2007
    ..We studied the relation between the age at treatment for undescended testis and the risk of testicular cancer...
  9. pmc Cancer risk in mothers of men operated for undescended testis
    Hadriano M Lacerda
    Cancer Epidemiology Unit, CPO and CeRMS, University of Turin, Italy
    PLoS ONE 5:e14285. 2010
    ..Several hormonal substances control this process and disruption of the foetal sex-hormones balance is a potential cause of undescended testis, however, to a great extent the aetiology of cryptorchidism is unclear...
  10. ncbi request reprint Preterm birth, low birth weight, and risk for esophageal adenocarcinoma
    Magnus Kaijser
    Clinical Epidemiology Unit, Department of Medicine at Karolinska Hospital, Stockholm, Sweden
    Gastroenterology 128:607-9. 2005
    ..Gastroesophageal reflux is common among preterm infants and those who are small for gestational age, and it is a strong risk factor for adenocarcinoma of the esophagus...
  11. doi request reprint Obstructive pulmonary disease in old age among individuals born preterm
    Eva Berggren Broström
    Department of Women s and Children s Health, K6, Child, Division of Neonatology, Karolinska Institutet, Karolinska Universitetssjukhuset, Q2 07, 171 76 Stockholm, Sweden
    Eur J Epidemiol 28:79-85. 2013
    ..77 (95% CI 1.39-5.54) and 5.67 (1.73-18.6), respectively. Low birth weight and preterm birth are risk factors for obstructive airways disease also among the old, but the importance of these risk factors differs between the sexes...
  12. doi request reprint Concordance of tumor differentiation among brothers with prostate cancer
    K Fredrik Jansson
    Urology Unit, Department of Surgery and Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 62:656-61. 2012
    ..Genetic factors seem to be of greater importance in prostate cancer than in other forms of cancer. Studies have suggested familial concordance in survival, but the extent to which that is due to tumor characteristics is not known...
  13. doi request reprint Perinatal risk factors for ischemic heart disease: disentangling the roles of birth weight and preterm birth
    Magnus Kaijser
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Circulation 117:405-10. 2008
    ..Several studies have reported an association between low birth weight and ischemic heart disease, but it remains unclear whether the association is mediated through poor fetal growth or short gestational duration...
  14. ncbi request reprint Will an adverse pregnancy outcome influence the risk of continued smoking in the next pregnancy?
    Sven Cnattingius
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Am J Obstet Gynecol 195:1680-6. 2006
    ..The purpose of this study was to study the effect of pregnancy outcomes on risks of continued smoking in subsequent pregnancy...
  15. doi request reprint Perinatal risk factors for childhood testicular germ-cell cancer: a Nordic population-based study
    Olof Stephansson
    Clinical Epidemiology Unit and Centre for Pharmacoepidemiology, Department of Medicine, Karolinska University Hospital and Institute, Stockholm, Sweden
    Cancer Epidemiol 35:e100-4. 2011
    ..The aim of the study was to investigate the association between perinatal characteristics and childhood testicular germ-cell cancer...
  16. ncbi request reprint Maternal smoking and the epidemic of testicular cancer--a nested case-control study
    Andreas Pettersson
    Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 120:2044-6. 2007
    ..91; 95% CI, 0.64-1.30), and there was no evidence of a dose-response effect. We conclude that the epidemic rise in testicular cancer in many populations is not due to the surge in smoking among women...
  17. doi request reprint Gestational hypertension, preeclampsia, and risk of testicular cancer
    Andreas Pettersson
    Department of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, Stockholm, Sweden
    Cancer Res 68:8832-6. 2008
    ....
  18. doi request reprint Increased risk of Barrett's esophagus among individuals born preterm or small for gestational age
    Lina Forssell
    Department of Neurobiology, Care Sciences and Society, Centre for Family Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin Gastroenterol Hepatol 11:790-4. 2013
    ..We assessed whether being born preterm or SGA increased the risk of developing Barrett's esophagus (BE) in adulthood...
  19. doi request reprint Open retropubic prostatectomy versus robot-assisted laparoscopic prostatectomy: a comparison of length of sick leave
    Lena Hohwü
    Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Scand J Urol Nephrol 43:259-64. 2009
    ..This study compared the length of sick leave after RALP with that after radical retropubic prostatectomy (RRP)...
  20. doi request reprint 15-year followup of a population based prostate cancer screening study
    Anders Kjellman
    Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    J Urol 181:1615-21; discussion 1621. 2009
    ..We evaluated long-term survival in attendees and nonattendees of a 1-time screening for prostate cancer...
  21. doi request reprint Time trends in the incidence of testicular cancer in childhood and young adulthood
    Hadriano M Lacerda
    Cancer Epidemiology Unit, University of Turin, Turin, Italy
    Cancer Epidemiol Biomarkers Prev 18:2042-5. 2009
    ..To further evaluate whether or not adult and childhood cancers share trend determinants and whether future adult testicular cancer incidences can be predicted through childhood testicular cancer incidences, their rates were compared...
  22. ncbi request reprint Fertility among brothers of patients with testicular cancer
    Lorenzo Richiardi
    Cancer Epidemiology Unit, CeRMS and Center for Oncology Prevention, University of Turin, V Santena 7, 10126, Turin, Italy
    Cancer Epidemiol Biomarkers Prev 14:2557-62. 2005
    ..To test if they share causes, we assessed fertility among brothers of patients with testicular cancer...
  23. ncbi request reprint Age at immigration and duration of stay in relation to risk for testicular cancer among Finnish immigrants in Sweden
    Anders Ekbom
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    J Natl Cancer Inst 95:1238-40. 2003
    ..Although the type of environmental exposures remains unknown, the results strongly indicate that early exposures are major determinants for testicular cancer...
  24. ncbi request reprint Fecundity and twinning rates as measures of fertility before diagnosis of germ-cell testicular cancer
    Lorenzo Richiardi
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden lorenzo richiardi meb ki se
    J Natl Cancer Inst 96:145-7. 2004
    ..Our study strongly supports evidence of an association between subfertility and the subsequent risk for testicular cancer...
  25. doi request reprint Risk of esophagitis among individuals born preterm or small for gestational age
    Lina Forssell
    Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden
    Clin Gastroenterol Hepatol 10:1369-75. 2012
    ..We investigated the association between preterm or SGA birth and risk of esophagitis early in life...
  26. doi request reprint Incidence of fractures causing hospitalisation in prostate cancer patients: results from the population-based PCBaSe Sweden
    Andreas Thorstenson
    Regional Cancer Centre, Karolinska University Hospital, Stockholm, Sweden
    Eur J Cancer 48:1672-81. 2012
    ..Data on incidence of fractures and risks in subgroups of men with prostate cancer are sparse. Our aim with this study is to report the risk of fractures among men with prostate cancer in a nationwide population-based study...
  27. ncbi request reprint Genetic and environmental risk factors for testicular cancer
    Lorenzo Richiardi
    Cancer Epidemiology Unit, CeRMS and CPO Piemonte, University of Turin, Turin, Italy
    Int J Androl 30:230-40; discussion 240-1. 2007
    ....
  28. ncbi request reprint Perinatal risk factors for cancer of the esophagus and gastric cardia: a nested case-control study
    Olof Akre
    Clinical Epidemiology Unit, Karolinska University Hospital, Solna, M9 01, SE 171 76 Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 15:867-71. 2006
    ..In this study, we aimed to test if there is an association between gestational duration and birth weight on the one hand, and risk of esophageal and cardia adenocarcinoma on the other...
  29. doi request reprint Cancer risk in hyperprolactinemia patients: a population-based cohort study
    Katarina Berinder
    Endocrine and Diabetes Unit, Department of Molecular Medicine and Surgery Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Eur J Endocrinol 165:209-15. 2011
    ..The aim of this study was to investigate cancer risk in hyperprolactinemia patients. Design A population-based matched cohort study in Sweden...
  30. pmc Mortality following hip fracture in men with prostate cancer
    Mieke Van Hemelrijck
    King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, United Kingdom Institute for Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 8:e74492. 2013
    ..Hip fractures are associated with increased mortality and are a known adverse effect of androgen deprivation therapy (ADT) for prostate cancer (PCa). It was our aim to evaluate how mortality after hip fracture is modified by PCa and ADT...
  31. ncbi request reprint Testicular cancer incidence in eight northern European countries: secular and recent trends
    Lorenzo Richiardi
    Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 13:2157-66. 2004
    ..However, it is not known whether these patterns have attenuated in recent years and whether they are similar for seminomas and nonseminomas, the two main histologic groups of testicular cancer...
  32. doi request reprint Subtype-specific risk of testicular tumors among immigrants and their descendants in Sweden, 1960 to 2007
    Omid Beiki
    Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 19:1053-65. 2010
    ....
  33. doi request reprint Radical prostatectomy: influence on serum and urinary androgen levels
    Mats Olsson
    Division of Urology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Prostate 70:200-5. 2010
    ..The role of the prostate as an active endocrine organ and the hormonal changes after radical prostatectomy (RP) has not been well studied. The objective of this study was to investigate the serum and urine hormonal changes after RP...
  34. ncbi request reprint Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients
    Lotus Mallbris
    Dermatology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden
    Eur J Epidemiol 19:225-30. 2004
    ..Severe psoriasis, however, here measured as repeated admissions, and early age at first admission, is associated with increased risk for cardiovascular death...
  35. ncbi request reprint Maternal lung cancer and testicular cancer risk in the offspring
    Magnus Kaijser
    Department of Medical Epidemiology, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 12:643-6. 2003
    ..Our results support the hypothesis that exposure to cigarette smoking in utero increases the risk of testicular cancer...
  36. doi request reprint Promoter methylation in APC, RUNX3, and GSTP1 and mortality in prostate cancer patients
    Lorenzo Richiardi
    Cancer Epidemiology Unit, University of Turin, Via Santena 7, 10126 Turin, Italy
    J Clin Oncol 27:3161-8. 2009
    ..Promoter methylation in APC was identified as a marker for prostate cancer progression...
  37. pmc How the effect of maternal age on the risk of childhood leukemia changed over time in Sweden, 1960-2004
    Milena Maria Maule
    Cancer Epidemiology Unit, Center for Experimental Research and Medical Studies and Center for Oncologic Prevention in Piedmont, University of Turin, Turin, Italy
    Environ Health Perspect 117:299-302. 2009
    ..Previous studies on the association between maternal age and risk of childhood leukemia found inconsistent results...
  38. doi request reprint How can we make cancer survival statistics more useful for patients and clinicians: an illustration using localized prostate cancer in Sweden
    Sandra Eloranta
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden
    Cancer Causes Control 24:505-15. 2013
    ..In this paper, we discuss the relative merits of recently developed alternatives to traditionally reported measures of cancer patient survival...
  39. doi request reprint Differences in citation rates by country of origin for papers published in top-ranked medical journals: do they reflect inequalities in access to publication?
    Olof Akre
    Cancer Epidemiology Unit, CeRMS and CPO Piemonte, University of Turin, Turin, Italy
    J Epidemiol Community Health 65:119-23. 2011
    ..Conversely, if the threshold is lowered for some countries, their papers will have a lower mean citation rate...
  40. ncbi request reprint Dihydrotestosterone levels and survival in screening-detected prostate cancer: a 15-yr follow-up study
    Anders Kjellman
    Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 53:106-11. 2008
    ..In this study, we evaluated serum DHT levels at the time of prostate-cancer diagnosis in relation to survival...
  41. ncbi request reprint Parity, pregnancy and neonatal outcomes in women treated for hyperprolactinaemia compared with a control group
    Katarina Berinder
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    Clin Endocrinol (Oxf) 67:393-7. 2007
    ..There are limited data on the fertility and pregnancy course among these women. The objective was to study parity, pregnancy and neonatal outcomes in women with hyperprolactinaemia as compared with a control group...
  42. doi request reprint Celiac disease is not a risk factor for infertility in men
    Daniela Zugna
    Cancer Epidemiology Unit, Center for Experimental Research and Medical Studies and Center for Oncologic Prevention in Piedmont, University of Turin, Turin, Italy
    Fertil Steril 95:1709-13.e1-3. 2011
    ..To examine fertility in men with biopsy-verified celiac disease (CD) in light of research that suggests that men with CD have impaired sperm quality...
  43. doi request reprint Time trends in human fecundability in Sweden
    Thomas H Scheike
    Department of Biostatistics, University of Copenhagen, Denmark
    Epidemiology 19:191-6. 2008
    ..Possible negative trends in male reproductive health are still debated, and their effect on human fertility might be negligible. Time-to-pregnancy (TTP) is a functional measure of couple fecundability...
  44. ncbi request reprint Body size at birth and adulthood and the risk for germ-cell testicular cancer
    Lorenzo Richiardi
    Department of Medical Epidemiology and Biostatistics Karolinska Institutet, SE 17177 Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 12:669-73. 2003
    ....
  45. ncbi request reprint Reduced risk of prostate cancer in men who are childless as compared to those who have fathered a child: a population based case-control study
    Aleksander Giwercman
    Fertility Centre, Scanian Andrology Centre, Malmo University Hospital, Malmo, Sweden
    Int J Cancer 115:994-7. 2005
    ..The risk for prostate cancer is reduced among childless men. A dysfunctioning reproductive apparatus fueling to a lesser extent prostatic growth, could be a plausible mechanism of this association...
  46. doi request reprint Similar at a glance, but not the same
    Olof Akre
    Int J Cancer 123:1480. 2008