Agneta Akesson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Serum transferrin receptor: a specific marker of iron deficiency in pregnancy
    A Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Am J Clin Nutr 68:1241-6. 1998
  2. pmc Cadmium-induced effects on bone in a population-based study of women
    Agneta Akesson
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 114:830-4. 2006
  3. pmc Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposure
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 113:1627-31. 2005
  4. ncbi request reprint Bone turnover from early pregnancy to postweaning
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Acta Obstet Gynecol Scand 83:1049-55. 2004
  5. ncbi request reprint Soluble transferrin receptor: longitudinal assessment from pregnancy to postlactation
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Obstet Gynecol 99:260-6. 2002
  6. pmc Cadmium exposure in pregnancy and lactation in relation to iron status
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Am J Public Health 92:284-7. 2002
  7. pmc Phlebotomy increases cadmium uptake in hemochromatosis
    A Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 108:289-91. 2000
  8. doi request reprint Cadmium-induced bone effect is not mediated via low serum 1,25-dihydroxy vitamin D
    Annette Engström
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Environ Res 109:188-92. 2009
  9. doi request reprint Retinol may counteract the negative effect of cadmium on bone
    Annette Engström
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    J Nutr 141:2198-203. 2011
  10. doi request reprint Total antioxidant capacity from diet and risk of myocardial infarction: a prospective cohort of women
    Susanne Rautiainen
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Med 125:974-80. 2012

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Serum transferrin receptor: a specific marker of iron deficiency in pregnancy
    A Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Am J Clin Nutr 68:1241-6. 1998
    ..Current markers of iron deficiency tend to be less reliable in pregnancy...
  2. pmc Cadmium-induced effects on bone in a population-based study of women
    Agneta Akesson
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 114:830-4. 2006
    ..Key words: biochemical bone markers, bone mineral density, cadmium, lead, osteoporosis, women...
  3. pmc Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposure
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 113:1627-31. 2005
    ..Although the effects were small, they may represent early signs of adverse effects, affecting large segments of the population. Subjects with diabetes seem to be at increased risk...
  4. ncbi request reprint Bone turnover from early pregnancy to postweaning
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Acta Obstet Gynecol Scand 83:1049-55. 2004
    ..To elucidate the sequences of changes in bone metabolism and bone density during pregnancy, lactation and postweaning...
  5. ncbi request reprint Soluble transferrin receptor: longitudinal assessment from pregnancy to postlactation
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Obstet Gynecol 99:260-6. 2002
    ..To assess the impact of pregnancy and lactation on iron status and erythropoiesis as measured by the soluble transferrin receptor (sTfR)...
  6. pmc Cadmium exposure in pregnancy and lactation in relation to iron status
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Am J Public Health 92:284-7. 2002
    ..The purpose of this study was to determine the impact of iron status on cadmium dose among pregnant women...
  7. pmc Phlebotomy increases cadmium uptake in hemochromatosis
    A Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 108:289-91. 2000
    ..Further studies are needed to confirm whether the disease decreased cadmium absorption and whether the absorption was dependent on the genotype...
  8. doi request reprint Cadmium-induced bone effect is not mediated via low serum 1,25-dihydroxy vitamin D
    Annette Engström
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Environ Res 109:188-92. 2009
    ..Hence, decreased circulating levels of 1,25(OH)(2)D are unlikely to be the proposed link between cadmium-induced effects on kidney and bone...
  9. doi request reprint Retinol may counteract the negative effect of cadmium on bone
    Annette Engström
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    J Nutr 141:2198-203. 2011
    ..016 among all women and P = 0.010 among never-smokers). Our findings suggest that adequate vitamin A status may counteract the adverse association between cadmium and BMD...
  10. doi request reprint Total antioxidant capacity from diet and risk of myocardial infarction: a prospective cohort of women
    Susanne Rautiainen
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Med 125:974-80. 2012
    ..The aim of this study was to examine how total antioxidant capacity of diet and antioxidant-containing foods were associated with incident myocardial infarction among middle-aged and elderly women...
  11. doi request reprint Associations between dietary cadmium exposure and bone mineral density and risk of osteoporosis and fractures among women
    Annette Engström
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    Bone 50:1372-8. 2012
    ..In separate analyses, dietary and urinary cadmium underestimated the association with bone effects...
  12. pmc Relation between dietary cadmium intake and biomarkers of cadmium exposure in premenopausal women accounting for body iron stores
    Bettina Julin
    Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health 10:105. 2011
    ..We aimed to assess the relationship between dietary cadmium intake assessed by analyses of duplicate food portions and cadmium concentrations in urine and blood, taking the toxicokinetics of cadmium into consideration...
  13. doi request reprint In utero and lactational exposure to Aroclor 1254 affects bone geometry, mineral density and biomechanical properties of rat offspring
    Lubna E Elabbas
    Institute of Environmental Medicine, Karolinska Institutet, P O Box 210, SE 17177 Stockholm, Sweden
    Toxicol Lett 207:82-8. 2011
    ..The results indicate that the observed bone effects are mainly driven by the dioxin-like congeners, although it cannot exclude the contribution of the non dioxin-like congeners to the exposure outcome...
  14. doi request reprint Long-term cadmium exposure and the association with bone mineral density and fractures in a population-based study among women
    Annette Engström
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    J Bone Miner Res 26:486-95. 2011
    ..U-Cd at low environmental exposure from food in a general population of women showed modest but significant association with both BMD and fractures, especially in never-smokers, indicating a larger concern than previously known...
  15. doi request reprint Long-term dietary acrylamide intake and breast cancer risk in a prospective cohort of Swedish women
    Susanna C Larsson
    Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 169:376-81. 2009
    ..These findings for Swedish women do not support the hypothesis that dietary acrylamide is positively associated with risk of breast cancer, at least not within the ranges of acrylamide consumed by this population...
  16. doi request reprint Dietary cadmium exposure and risk of postmenopausal breast cancer: a population-based prospective cohort study
    Bettina Julin
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Cancer Res 72:1459-66. 2012
    ..73). Overall, these results suggest a role for dietary cadmium in postmenopausal breast cancer development...
  17. ncbi request reprint Major dietary patterns and risk of renal cell carcinoma in a prospective cohort of Swedish women
    Bahram Rashidkhani
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    J Nutr 135:1757-62. 2005
    ..95; and 0.72; 95% CI, 0.42-1.22, respectively, P = 0.08 by Wald test); the association was clearer among women < or = 65 y (P = 0.02 by Wald test). Our data suggest an inverse association between Drinker pattern and the risk of RCC...
  18. doi request reprint Benchmark dose for cadmium-induced osteoporosis in women
    Yasushi Suwazono
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Lett 197:123-7. 2010
    ..Our results provide additional scientific support for the low tolerably weekly intake (TWI) of cadmium set by the European Food Safety Authority in 2009...
  19. doi request reprint Cadmium in diet and risk of cardiovascular disease in women
    Bettina Julin
    From the aInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden and bEuropean Food Safety Authority, Parma, Italy
    Epidemiology 24:880-5. 2013
    ..We evaluated the association between quartiles of food frequency questionnaire-based estimates of cadmium exposure from food (the predominant source of exposure to the metal) and incident cardiovascular disease and its subtypes...
  20. doi request reprint Association between dairy food consumption and risk of myocardial infarction in women differs by type of dairy food
    Emma Patterson
    Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    J Nutr 143:74-9. 2013
    ..Failure to consider dairy foods as a heterogeneous group in future studies could hamper important insights of relevance for the development of dietary guidelines...
  21. doi request reprint Multivitamin use and breast cancer incidence in a prospective cohort of Swedish women
    Susanna C Larsson
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Clin Nutr 91:1268-72. 2010
    ..Many women use multivitamins in the belief that these supplements will prevent chronic diseases such as cancer and cardiovascular disease. However, whether the use of multivitamins affects the risk of breast cancer is unclear...
  22. doi request reprint Dietary acrylamide intake and risk of colorectal cancer in a prospective cohort of men
    Susanna C Larsson
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, SE 17177 Stockholm, Sweden
    Eur J Cancer 45:513-6. 2009
    ..71-1.31) for colon cancer and 0.91 (95% CI 0.62-1.34) for rectal cancer. In conclusion, this study provides no evidence that dietary acrylamide in amounts typically consumed by Swedish men is associated with risk of colorectal cancer...
  23. doi request reprint Long-term dietary acrylamide intake and risk of endometrial cancer in a prospective cohort of Swedish women
    Susanna C Larsson
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 124:1196-9. 2009
    ..In conclusion, these findings do not support the hypothesis that dietary acrylamide intake is positively associated with risk of endometrial cancer, at least not within the ranges of acrylamide consumed in this population...
  24. doi request reprint Validation of questionnaire-based long-term dietary exposure to polychlorinated biphenyls using biomarkers
    Charlotte Bergkvist
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Mol Nutr Food Res 56:1748-54. 2012
    ..We validated long-term food frequency questionnaire (FFQ)-based dietary PCB exposure against concentrations of six PCB congeners in serum...
  25. doi request reprint Long-term dietary acrylamide intake and risk of epithelial ovarian cancer in a prospective cohort of Swedish women
    Susanna C Larsson
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 18:994-7. 2009
    ..Whether dietary acrylamide intake is associated with the risk of cancer in humans is uncertain. We aimed to assess the relation between dietary acrylamide intake and the incidence of epithelial ovarian cancer...
  26. doi request reprint Dietary cadmium exposure and fracture incidence among men: a population-based prospective cohort study
    Laura D K Thomas
    Institute of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet, Stockholm, Sweden
    J Bone Miner Res 26:1601-8. 2011
    ..This association was independent of smoking and was most pronounced among men with low fruit and vegetable consumption...
  27. doi request reprint Cadmium-induced effects on cellular signaling pathways in the liver of transgenic estrogen reporter mice
    Imran Ali
    Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Toxicol Sci 127:66-75. 2012
    ..Furthermore, we conclude that the estrogen-like effects of Cd are likely to result from a mechanism different from steroidal estrogens...
  28. doi request reprint Perinatal exposure to environmental contaminants detected in Canadian Arctic human populations changes bone geometry and biomechanical properties in rat offspring
    Lubna E Elabbas
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    J Toxicol Environ Health A 74:1304-18. 2011
    ..These findings could be significant from a health risk assessment point of view...
  29. doi request reprint Long-term dietary cadmium intake and postmenopausal endometrial cancer incidence: a population-based prospective cohort study
    Agneta Akesson
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Cancer Res 68:6435-41. 2008
    ..Our results support the hypothesis that cadmium may exert estrogenic effects and thereby increase the risk of hormone-related cancers...
  30. ncbi request reprint Toxic metals and the menopause
    Marie Vahter
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    J Br Menopause Soc 10:60-4. 2004
    ..There is a significant release of bone lead after the menopause, in association with the acceleration of bone resorption. Thus, postmenopausal women may be at increased risk of adverse effects of lead...
  31. pmc Benchmark dose for cadmium-induced renal effects in humans
    Yasushi Suwazono
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 114:1072-6. 2006
    ..Our goal in this study was to explore the use of a hybrid approach to calculate benchmark doses (BMDs) and their 95% lower confidence bounds (BMDLs) for renal effects of cadmium in a population with low environmental exposure...
  32. ncbi request reprint Influence of iron and zinc status on cadmium accumulation in Bangladeshi women
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Appl Pharmacol 222:221-6. 2007
    ..In conclusion, low iron stores were associated with increased cadmium accumulation, but only at adequate zinc status...
  33. ncbi request reprint Erythropoietin and intravenous iron therapy in postpartum anaemia
    Elle Wågström
    Department of Obstetrics and Gynecology, South Stockholm General Hospital, Stockholm, Sweden
    Acta Obstet Gynecol Scand 86:957-62. 2007
    ..We assessed whether recombinant human erythropoietin (rhEPO) enhances a rise in haemoglobin concentration in postpartum anaemia compared to intravenous iron alone...
  34. pmc Elevated manganese concentrations in drinking water may be beneficial for fetal survival
    Syed Moshfiqur Rahman
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    PLoS ONE 8:e74119. 2013
    ..We assessed the effects of drinking water Mn exposure during pregnancy upon fetal and infant survival...
  35. pmc Inorganic mercury and methylmercury in placentas of Swedish women
    Karolin Ask
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 110:523-6. 2002
    ..We found no correlations between I-Hg and selenium. This study increases the understanding of Hg, in its different forms, in human placenta and how they are related to maternal and fetal exposure...
  36. ncbi request reprint Associations of diet, supplement use, and ultraviolet B radiation exposure with vitamin D status in Swedish women during winter
    Ann Burgaz
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Am J Clin Nutr 86:1399-404. 2007
    ..Vitamin D is produced endogenously after sun exposure but can also be obtained from natural food sources, food fortification, and dietary supplements...
  37. doi request reprint Dietary acrylamide intake and prostate cancer risk in a prospective cohort of Swedish men
    Susanna C Larsson
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 18:1939-41. 2009
    ..We examined the association between dietary acrylamide intake and risk of prostate cancer in a cohort of men...
  38. doi request reprint Multivitamin use and the risk of myocardial infarction: a population-based cohort of Swedish women
    Susanne Rautiainen
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Clin Nutr 92:1251-6. 2010
    ..Dietary supplements are widely used in industrialized countries...
  39. ncbi request reprint Combined effect of low-risk dietary and lifestyle behaviors in primary prevention of myocardial infarction in women
    Agneta Akesson
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Box 210, 17177 Stockholm, Sweden
    Arch Intern Med 167:2122-7. 2007
    ..Limited data are available on the benefit of combining healthy dietary and lifestyle behaviors in the prevention of myocardial infarction (MI) in women...
  40. ncbi request reprint Dietary supplement use and mortality in a cohort of Swedish men
    Maria Messerer
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Br J Nutr 99:626-31. 2008
    ..In conclusion, we cannot exclude that the use of dietary supplements is harmful for smokers. On the other hand, among men with an insufficient diet, the use of supplements might be beneficial in reducing CVD mortality...
  41. doi request reprint Dietary cadmium exposure and kidney stone incidence: a population-based prospective cohort study of men & women
    Laura D K Thomas
    Institute of Environmental Medicine, Unit of Nutritional Epidemiology, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden
    Environ Int 59:148-51. 2013
    ..99 (95% CI: 0.89-1.43), comparing the highest tertile with the lowest. In conclusion, our results do not support a strong association between dietary cadmium and kidney stone risk at the exposure levels seen in the general population. ..
  42. ncbi request reprint Gender differences in the disposition and toxicity of metals
    Marie Vahter
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Environ Res 104:85-95. 2007
    ..Experimental studies indicate major gender differences in arsenic-induced cancer. Obviously, research on gender-related differences in health effects caused by metals needs considerable more focus in the future...
  43. pmc Estrogen-like effects of cadmium in vivo do not appear to be mediated via the classical estrogen receptor transcriptional pathway
    Imran Ali
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 118:1389-94. 2010
    ..Cadmium (Cd), a ubiquitous food contaminant, has been proposed to be an endocrine disruptor by inducing estrogenic responses in vivo. Several in vitro studies suggested that these effects are mediated via estrogen receptors (ERs)...
  44. ncbi request reprint Alcohol consumption and risk of renal cell carcinoma: a prospective study of Swedish women
    Bahram Rashidkhani
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 117:848-53. 2005
    ..44, 95% CI 0.22-0.88. Results from our prospective cohort study of middle-aged and elderly women indicate that moderate alcohol consumption may be associated with decreased risk of RCC...
  45. ncbi request reprint Coffee consumption and risk of myocardial infarction among older Swedish women
    Sarah A Rosner
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Epidemiol 165:288-93. 2007
    ..Contrary to previous case-control studies, the authors concluded that coffee consumption does not increase MI risk. Coffee consumption of >/=5 cups/week was nonsignificantly inversely associated with MI risk among older Swedish women...
  46. ncbi request reprint Long-term stability of food patterns identified by use of factor analysis among Swedish women
    P K Newby
    Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:626-33. 2006
    ..Testing whether patterns measured over a long time period can be used in analytic studies is the next step in assessing the validity of this method...
  47. ncbi request reprint Longitudinal changes in food patterns predict changes in weight and body mass index and the effects are greatest in obese women
    P K Newby
    The Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Nutr 136:2580-7. 2006
    ..Pattern analysis is helpful in generating hypotheses regarding the role of diet in obesity, and additional research is needed to understand which elements of our patterns are protective or risk factors for weight gain...