Anders Ahlbom

..For slow-growing tumors such as meningioma and acoustic neuroma, as well as for glioma among long-term users, the absence of association reported thus far is less conclusive because the observation period has been too short...

..Physicians should be aware of the potential cardiovascular implications of epilepsy...

..The aim of the present study was to evaluate whether leisure-time physical activity compensates for the increased risk of acute myocardial infarction associated with overweight and obesity...

..Results indicate that physical activity is associated with a reduced risk of mortality not due to genetic selection. This finding supports a causal link between physical activity and mortality...

..The aim of the present study was to examine the potential role of tea consumption in the previous 12 months in primary and secondary prevention of AMI...

..7 (95% confidence interval: 0.9, 7.5). Hormone usage was not associated with glioma risk in this study. The findings suggest that the use of female sex steroids may increase the risk of meningioma...

..Numerous studies have shown that higher body mass index (BMI) is associated with higher mortality. We investigated the extent to which this association might be explained by genetic factors...

..We tested the hypothesis that occupational EMF exposure increases the risk of myocardial infarction in a large population-based case-control study of myocardial infarction, with detailed information on potential confounders...

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..Depression is considered a risk factor for coronary heart disease (CHD) in initially CHD-free populations. Subclinical CHD or other somatic causes of depressive symptoms might account for the association, however...

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..To study diabetes, acute myocardial infarction, and stroke as risk factors for unprovoked seizures in a population-based cohort with incident cases of epilepsy...

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..The risk estimate did not increase, regardless of type of phone and amount of use. The authors conclude that the data do not support the hypothesis that mobile phone use is related to an increased risk of parotid gland tumors...

..This study includes a large number of long-term mobile phone users, and the authors conclude that the data do not support the hypothesis that mobile phone use is related to an increased risk of glioma or meningioma...

..This technology is constantly changing and there is a need for continued research on this issue. Almost no epidemiologic data are available for static fields...

..The factors of interest were demographic and socioeconomic factors, prior health, and collision factors...

..The authors aimed to illustrate the possible magnitude of this potential bias using data from a cross-sectional study on coffee consumption and work stress in relation to type 2 diabetes...

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..Our aim was to investigate a wide range of occupational exposures, individual occupational titles and socioeconomic status (SES) as potential risk factors for acoustic neuroma...

..The aim of this study was to investigate if expectations for recovery are a prognostic factor after experiencing a WAD...

..Special interest was focused on potential interaction among these aspects of physical activity...

..To study hospitalization for psychiatric disorders before and after onset of unprovoked epileptic seizures/epilepsy...

..In Cohort III, immune-related discharge diagnoses are also inversely associated with glioma (HR = 0.46; 95% CI = 0.14-1.49). There is no strong evidence against (and some for) the hypothesis that allergies reduce glioma risk...

..78). No association was found for prostate cancer. We conclude that age is an important effect modifier of cancer risk associated with obesity and that obesity and overweight in young adult life may affect cancer risk also later in life...

..The aim of this study was to assess whether long-term use of Swedish moist snuff (widely used among Swedish men) increases the risk of acute myocardial infarction...

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..The aim of this study was to investigate the genetic effects on leisure-time physical activity using data from the Swedish Twin Registry...

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..The question is whether this also implies an increased risk of myocardial infarction, either through the triggering effect of acute stress, or through accumulation of stress over several months...

..There is still a lack of follow-up studies of well-characterized patient cohorts assessing the relative importance of these factors...

..To investigate whether knowledge of the risks and properties of tobacco among adolescents influences their future use of cigarettes and smokeless tobacco in different directions...

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..To investigate whether sleep disturbances and low psychological well-being are associated with an increased risk of autoimmune diabetes in adults (including LADA and type 1 diabetes) and type 2 diabetes...

..These are changes that have been observed for several diseases indicating that the challenges posed by the ageing population may not be as severe as they may seem when considering the demographic component alone...

..Several studies have identified occupational exposure to extremely low-frequency electromagnetic fields (EMF) as a potential risk factor for neurodegenerative disease, but the evidence is contradictory and inconclusive...

..By using numerically identical examples, we show that adjustment for a common consequence of the exposure and the outcome can lead to as much bias as absence of necessary adjustment for a confounder...

..89%, 95% confidence interval, CI: 3.69, 10.04), or by the simple 'dichotomization'-method (6.88%, 95%CI: 3.81, 9.84). The method is very easy to apply to population-based case-referent studies analyzed by logistic regression...

..However, extensive research activities are ongoing and much more data will be available in the near future. This situation of scientific uncertainty and considerable public concern creates dilemmas for decision makers...

..To investigate whether the risk for autoimmune diabetes in adults differs between socioeconomic groups and to compare such risk with that for type 2 diabetes...

..Cohort study of subjects with whiplash-associated disorders (WAD)...

..Radiofrequency exposure from mobile phones is concentrated to the tissue closest to the handset, which includes the auditory nerve. If this type of exposure increases tumor risk, acoustic neuroma would be a potential concern...

..Case fatality after AMI is seemingly increased among snus users, but this relationship may be due to confounding by socioeconomic or life style factors...

..We compare the random splitting procedure to using the full data sample for analysis, by using a Bayesian perspective with consideration taken to prior probability of a false positive finding...

..The odds ratio with 95% confidence interval was 3.7 (CI 1.2-11.0) for MS and 8.0 (2.2-30.0) for SLE, suggesting an increased risk of unprovoked seizures in patients with both these diagnoses...

..A second aim was to analyse the impact of the volume of earlier alcohol use in abstainers...

..Hip fracture patients have a substantially increased risk of death that persists for at least 6 years post-fracture. The relative excess mortality is independent of comorbidity and known hip fracture risk factors...

..Finally, we investigated the combination of SOC and demands or SOC and decision latitude in association with the disease...

..CHOP chemotherapy is more efficacious than CNOP at equitoxic (myelosuppression) doses. CHOP is, however, associated with more alopecia and gastrointestinal toxicity...

..However, the intermediate field exposure category (0.1-0.19 microT) showed poor correlation to the 24 hr personal measurements...

..The data in this study cannot exclude under-diagnosis and, to a lesser degree, under-registration as a partial explanation of the low incidence rates of malignant CNS tumours in children in Costa Rica...

..We investigated the association between the risk of suicide in persons with epilepsy and clinical factors that might increase or have been suggested to increase the risk of suicide...

..The occurrence of excess epilepsy > or =8 years before HGG diagnosis suggests a relatively long preclinical phase, but excess diabetes or stroke appear late in HGG development...

..An adverse influence of pregnancy on the risk of death in women with cutaneous melanoma was suggested historically by anecdotal reports. Previous studies included small numbers of women observed for short periods...

..Finally, we show how this output can be used as input in an Excel sheet that is set up to calculate the measures of biological interaction to be used for the assessment...

..Although some other point estimates were elevated, they lacked statistical significance. The results do not provide evidence of a strong association between occupational exposures and glioma development...

..To investigate mortality and especially the incidence of sudden unexpected death in epilepsy (SUDEP) in a population-based cohort of epilepsy surgery patients...

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..There are few observational studies of school and class risk factors for smoking behavior in preadolescence...

..This effort represents an interesting case study of a scientific inquiry that has been successfully resolved despite numerous methodological difficulties inherent in research on low-level environmental exposures...

..94). Our findings provide support for the role of folate metabolism in the development of primary brain tumors. In particular, genotypes associated with increased 5,10-methylenetetrahydrofolate levels are associated with elevated risk...

..Because there is less previous evidence for a role of NQO1, CYP1A1, GSTM1, and GSTT1 variants, we restricted analysis of these variants to a small preliminary study...

..Therefore, we tested the hypothesis that polymorphisms and haplotypes in p53 and ATM could be associated with glioma and meningioma risk...

..These results do not support the hypotheses that nighttime measures are more appropriate; hence, the observed association between ELF EMF and childhood leukemia still lacks a plausible explanation...

..This study was performed to investigate the effect of power frequency magnetic fields...

..12 (95% CI: 1.40, 3.20). The findings of an increased risk of acoustic neuroma with loud noise exposure support previous research...

..Parental exposure to pesticides and the risk of leukemia in offspring were examined in a population-based case-control study in Costa Rica...

..The effect of nondifferential misclassification of exposure must be considered a potential cause of the negative findings...

..Previous reviews of associations of apolipoprotein E (apoE) genotype and coronary disease have been dominated by smaller studies that are liable to biases...

..The present study was conducted to see whether these previous findings could be confirmed and whether shift workers are at elevated risk for cancer at additional sites...

..01). Our results provide additional support for the hypothesis that low penetrance variants contribute to the risk of developing glioma and suggest that a genetic variant located in or around the CHAF1A gene contributes to disease risk...

..This study is novel in suggesting an increased risk of brain tumors when the analysis is restricted to those with a history of cancer in the family. However, we cannot rule out the possibility that these results are due to chance...

..A relationship between risk of meningioma and exposure to ionizing radiation is also well known and led us to examine whether variants in DNA repair genes contribute to disease susceptibility...

..10-1.70; P = 0.004). The association of CASP8 D302H with glioma risk indicates the importance of inherited variation in the apoptosis pathway in susceptibility to this form of primary brain tumor...