Ingrid Agartz

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Reliability and reproducibility of brain tissue volumetry from segmented MR scans
    I Agartz
    Dept Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet and Hospital, Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 251:255-61. 2001
  2. ncbi request reprint CSF monoamine metabolites and MRI brain volumes in alcohol dependence
    Ingrid Agartz
    Section on Electrophysiology and Brain Imaging, Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 1256, USA
    Psychiatry Res 122:21-35. 2003
  3. doi request reprint Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 17176 Stockholm, Sweden
    Eur Neuropsychopharmacol 21:700-4. 2011
  4. doi request reprint Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers
    Erik G Jonsson
    Department of Clinical Neuroscience, Karolinska Institute and Hospital, Stockholm, Sweden
    J Neural Transm 115:1695-9. 2008
  5. doi request reprint The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:387-96. 2010
  6. pmc D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 262:549-56. 2012
  7. pmc Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
    Eva Lindholm Carlström
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, Stockholm, Sweden
    Behav Brain Funct 8:24. 2012
  8. doi request reprint DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
    Erik G Jonsson
    HUBIN project, Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Neuropsychobiology 59:142-50. 2009
  9. doi request reprint Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:976-82. 2008
  10. doi request reprint Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Psychiatry Res 180:63-7. 2010

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Reliability and reproducibility of brain tissue volumetry from segmented MR scans
    I Agartz
    Dept Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet and Hospital, Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 251:255-61. 2001
    ..The reliability and consistency of the measurements of the segmented volumes were excellent. The segmentation is robust and rapid and the volume measurements are plausible and suitable for quantitative studies in clinical brain research...
  2. ncbi request reprint CSF monoamine metabolites and MRI brain volumes in alcohol dependence
    Ingrid Agartz
    Section on Electrophysiology and Brain Imaging, Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 1256, USA
    Psychiatry Res 122:21-35. 2003
    ..In alcoholic women and men, monoaminergic neurotransmission measured by the CSF MAM HVA, MHPG, and 5-HIAA is not significantly correlated with the size of different brain structures...
  3. doi request reprint Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 17176 Stockholm, Sweden
    Eur Neuropsychopharmacol 21:700-4. 2011
    ..The results suggest that genetic variation in DTNBP1 gene affects the regulation of dopamine and serotonin turnover in the central nervous system of healthy volunteers...
  4. doi request reprint Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers
    Erik G Jonsson
    Department of Clinical Neuroscience, Karolinska Institute and Hospital, Stockholm, Sweden
    J Neural Transm 115:1695-9. 2008
    ..01). The results suggest that BDNF gene variation participates in regulation of norepinephrine turnover rates in the central nervous system of human subjects...
  5. doi request reprint The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:387-96. 2010
    ....
  6. pmc D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 262:549-56. 2012
    ....
  7. pmc Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
    Eva Lindholm Carlström
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, Stockholm, Sweden
    Behav Brain Funct 8:24. 2012
    ..In this study, we wanted to elucidate whether SLC6A4 variations is involved in attempted suicide among patients with schizophrenia in a Scandinavian case-control sample...
  8. doi request reprint DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
    Erik G Jonsson
    HUBIN project, Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Neuropsychobiology 59:142-50. 2009
    ....
  9. doi request reprint Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:976-82. 2008
    ..However, when combined with previous studies in meta-analyses there is still evidence for association between the MTHFR C677T polymorphism and schizophrenia. Additional studies are warranted to shed further light on these relationships...
  10. doi request reprint Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Psychiatry Res 180:63-7. 2010
    ..The results suggest that TPH1 gene variation participates in the regulation of serotonin and dopamine turnover rates in the central nervous system of healthy human subjects...
  11. pmc Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population
    Peter Saetre
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 159:981-6. 2012
    ..The present results do not suggest that the investigated MTHFR polymorphism has any significant influence on age at onset of schizophrenia in the Nordic population...
  12. doi request reprint Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
    Maria Vares
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:610-8. 2010
    ..008). The MTHFR C677T polymorphism may play a role as a modifying factor for age of onset in schizophrenia...
  13. pmc Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
    Maria Holtze
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    J Psychiatry Neurosci 37:53-7. 2012
    ..This compound is an end-metabolite of the kynurenine pathway, and its formation indirectly depends on the activity of kynurenine 3-monooxygenase (KMO), the enzyme converting kynurenine to 3-hydroxykynurenine...
  14. ncbi request reprint Potential genetic variants in schizophrenia: a Bayesian analysis
    Hakan Hall
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    World J Biol Psychiatry 8:12-22. 2007
    ..The results indicate that the Bayesian statistical method gives additional possibilities in the search for risk factors for schizophrenia or other complex disorders...
  15. doi request reprint Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 156:215-24. 2011
    ..The present results suggest that the investigated MTHFR polymorphisms do not influence age of onset in schizophrenia...
  16. doi request reprint Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Schizophr Res 106:237-41. 2008
    ....
  17. doi request reprint Neurocognitive function in long-term treated schizophrenia: a five-year follow-up study
    Maria Ekerholm
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, SE 171 76 Stockholm, Sweden
    Psychiatry Res 200:144-52. 2012
    ..5 years in patients with long-term treated schizophrenia, in line with previous scientific research. The authors discuss the impact of age and education and limitations of the study...
  18. doi request reprint Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
    Anna K Kähler
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 159:722-30. 2012
    ..In conclusion, DISC1 SNPs might impact brain structural variation, possibly differently in psychosis patients versus controls, but independent replication will be needed to confirm our findings...
  19. ncbi request reprint Frontal and temporal volume size of grey and white matter in patients with schizophrenia: an MRI parcellation study
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet, Stockholm 171 76, Sweden
    Eur Arch Psychiatry Clin Neurosci 257:304-7. 2007
    ..Schizophrenic patients had a greater CSF volume in the frontal and temporal lobes. These results suggest that volume reduction in the cerebrum is prominent in the frontal and temporal lobes in both men and women with schizophrenia...
  20. pmc Morphological correlates to cognitive dysfunction in schizophrenia as studied with Bayesian regression
    Glenn Laywer
    Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden
    BMC Psychiatry 6:31. 2006
    ..This work explored a model encompassing all of these possibilities to identify the strongest morphological relationships to cognitive skill in schizophrenia...
  21. ncbi request reprint Selective reduction of the posterior superior vermis in men with chronic schizophrenia
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Informatics Center HUBIN, Karolinska Institute and Hospital, SE 171 76 Stockholm, Sweden
    Schizophr Res 55:61-7. 2002
    ..The findings support the view that within the cerebellum the posterior superior vermis may be selectively reduced in men with chronic schizophrenia...
  22. ncbi request reprint Smaller cerebellar vermis but not hemisphere volumes in patients with chronic schizophrenia
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Infomatics Center HUBIN, Karolinska Institute and Hospital, Stockholm, Sweden
    Am J Psychiatry 160:1614-7. 2003
    ..In this study, they tested whether posterior superior vermis reduction would be seen in a larger group of schizophrenia patients, both male and female...
  23. ncbi request reprint BDNF gene variants and brain morphology in schizophrenia
    Ingrid Agartz
    Department of Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 141:513-23. 2006
    ..Trends for associations between several polymorphisms/haplotype estimates and MRI volumes were found. BDNF gene variation may influence brain morphology. The effects may be different in patients with schizophrenia and healthy subjects...
  24. ncbi request reprint Altered white matter/gray matter proportions in the striatum of patients with schizophrenia: a volumetric MRI study
    Chiharu Tamagaki
    Human Brain Informatics, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Am J Psychiatry 162:2315-21. 2005
    ..Anatomical structures of the striatum were studied in 58 patients with schizophrenia and 56 healthy comparison subjects of both genders matched for age and handedness...
  25. ncbi request reprint Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Prog Neuropsychopharmacol Biol Psychiatry 30:924-33. 2006
    ..Thus, the BDNF gene may confer susceptibility to schizophrenia. Additional studies are warranted to shed further light on this possibility...
  26. ncbi request reprint MR volumetry during acute alcohol withdrawal and abstinence: a descriptive study
    Ingrid Agartz
    Karolinska Institutet, Department of Clinical Neuroscience, Clinical Alcohol and Drug Addiction Research Section and Human Brain Informatics, Psychiatry Section, Karolinska Hospital, Stockholm SE 171 76, Sweden
    Alcohol Alcohol 38:71-8. 2003
    ....
  27. ncbi request reprint Assessing apathy: the use of the Apathy Evaluation Scale in first episode psychosis
    Ann Faerden
    Section for Psychosis Research, Division of Psychiatry, Building 49, Ulleval University Hospital, Krikeveien 166, 0407 Oslo, Norway
    Eur Psychiatry 23:33-9. 2008
    ..The main aims of this study were to examine the psychometric properties of the AES-C and its relationship to the Positive and Negative Syndrome Scale (PANSS)...
  28. ncbi request reprint A morphometric magnetic resonance method for measuring cranial, facial and brain characteristics for application to schizophrenia: part 1
    Karin M Henriksson
    Department of Psychiatric Epidemiology, University Hospital, Lund University, Barngatan 2, S 221 85, Lund, Sweden
    Psychiatry Res 147:173-86. 2006
    ..In a second article we will use this method to compare 3D craniofacial measurements and shape between schizophrenia patients and healthy controls...
  29. ncbi request reprint Cerebellar volumes in men with schizophrenia and alcohol dependence
    Katarina Varnas
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Clin Neurosci 61:326-9. 2007
    ..The results provide indications for differential morphological abnormalities of the cerebellar vermis in patients with schizophrenia and alcohol dependence...
  30. ncbi request reprint Effects of alcohol consumption and antipsychotic medication on brain morphology in schizophrenia
    Ragnar Nesvåg
    Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway
    Schizophr Res 90:52-61. 2007
    ..This study demonstrates that alcohol consumption is an important factor for variation in WM volumes, and this effect should be taken into account in all studies evaluating brain volumes from MR images...
  31. ncbi request reprint Reduced grey and white matter volumes in the temporal lobe of male patients with chronic schizophrenia
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Informatics HUBIN, Psychiatry Section, Karolinska Institute and Hospital, 17176 Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 252:120-3. 2002
    ..The volume of white matter in the whole brain also appears to be reduced. Among the different brains regions, grey matter reduction was significant only in the temporal region...
  32. ncbi request reprint Minor physical anomalies in schizophrenia: is age a confounding factor?
    Karin M Henriksson
    Psychol Med 38:154-6. 2008
  33. ncbi request reprint Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication
    Ragnar Nesvåg
    Department of Psychiatric Research, Diakonhjemmet Hospital, and Institute of Psychiatry, University of Oslo, Norway
    Schizophr Res 98:16-28. 2008
    ..The lack of significant influence from antipsychotic medication supports that regional cortical thinning is an inherent feature of the neurobiological disease process in schizophrenia...
  34. doi request reprint Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
    Anna K Kähler
    TOP Project, Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 147:1089-100. 2008
    ....
  35. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
    ..Thus, we tested the hypothesis that variants of the glycolytic genes are associated with schizophrenia or at least with gender-associated aspects of the illness...
  36. doi request reprint Craniofacial dysmorphology and cortical thickness in men with schizophrenia
    Brendan D Kelly
    Schizophr Res 103:322-3. 2008
  37. ncbi request reprint Is craniofacial dysmorpholgy correlated with structural brain anomalies in schizophrenia?
    Brendan D Kelly
    The Stanley Research Unit, Department of Adult Psychiatry, Hospitaller Order of St John of God, Cluain Mhuire Centre, Newtownpark Avenue, Blackrock, Co Dublin, Ireland
    Schizophr Res 80:349-55. 2005
    ..These findings suggest that craniofacial dysmorphology and anomalies of brain morphology may be associated with independent processes in the etiology of schizophrenia...
  38. doi request reprint Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia
    Katarina Varnas
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Psychiatr Genet 18:177-83. 2008
    ..To investigate associations between brain-derived neurotrophic factor (BDNF) gene polymorphisms and regional frontal cortical thickness and volume in patients with schizophrenia and healthy control participants...
  39. ncbi request reprint A pilot study of facial, cranial and brain MRI morphometry in men with schizophrenia: part 2
    Karin Maria Henriksson
    Unit of Psychiatric Epidemiology, Barngatan 2, University Hospital, Lund University, S 221 85, Lund, Sweden
    Psychiatry Res 147:187-95. 2006
    ..In contrast, none of the patient-control differences for the new "interior" (cranial-brain) distances reached statistical significance. These results need to be retested on a larger sample of both sexes...