Jan Adolfsson

Summary

Affiliation: Karolinska University Hospital
Country: Sweden

Publications

  1. ncbi Individualized assessment of prostate cancer risk
    Jan Adolfsson
    Karolinska Institute, Stockholm, Sweden
    Nat Clin Pract Urol 3:522-3. 2006
  2. ncbi Commentary: on the incidence of histological prostate cancer and the probable diagnosis of cases with tumours too small to produce symptoms or to attract attention on physical examination--the findings of Dr Arnold Rice Rich
    Jan Adolfsson
    Oncologic Centre, Karolinska University Hospital, CLINTEC, Karolinska Institute, Stockholm, Sweden
    Int J Epidemiol 36:285-7. 2007
  3. ncbi Clinical characteristics and primary treatment of prostate cancer in Sweden between 1996 and 2005
    Jan Adolfsson
    Oncological Centre, Karolinska University Hospital, CLINTEC, Karolinska Institute, Stockholm, Sweden
    Scand J Urol Nephrol 41:456-77. 2007
  4. doi Watchful waiting and active surveillance: the current position
    Jan Adolfsson
    Oncological Centre, CLINTEC, Karolinska Institutet, Stockholm, Sweden
    BJU Int 102:10-4. 2008
  5. ncbi The 20-Yr outcome in patients with well- or moderately differentiated clinically localized prostate cancer diagnosed in the pre-PSA era: the prognostic value of tumour ploidy and comorbidity
    Jan Adolfsson
    Oncologic Center, CLINTEC, Karolinska Institute, Stockholm, Sweden
    Eur Urol 52:1028-35. 2007
  6. doi Differences according to socioeconomic status in the management and mortality in men with high risk prostate cancer
    Anders Berglund
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur J Cancer 48:75-84. 2012
  7. ncbi Prognostic significance of homozygous deletions and multiple duplications at the CDKN2A (p16INK4a)/ARF (p14ARF) locus in urinary bladder cancer
    Petra J Berggren de Verdier
    Clinical Center Epidemiology, Department of Oncology Pathology, Karolinska University Hospital, Stockholm, Sweden
    Scand J Urol Nephrol 40:363-9. 2006
  8. ncbi A single-nucleotide polymorphism in the XPG gene, and tumour stage, grade, and clinical course in patients with nonmuscle-invasive neoplasms of the urinary bladder
    Shigeru Sakano
    Department of Biosciences at Novum, Karolinska Institutet, Huddinge, Sweden
    BJU Int 97:847-51. 2006
  9. ncbi A population-based study of 538 patients with newly detected urinary bladder neoplasms followed during 5 years
    Per Larsson
    Clinical Cancer Epidemiology, Department of Oncology Pathology, Karolinska Institute, Stockholm, Sweden
    Scand J Urol Nephrol 37:195-201. 2003
  10. ncbi Prostate-specific antigen levels as a predictor of lethal prostate cancer
    Katja Fall
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
    J Natl Cancer Inst 99:526-32. 2007

Detail Information

Publications57

  1. ncbi Individualized assessment of prostate cancer risk
    Jan Adolfsson
    Karolinska Institute, Stockholm, Sweden
    Nat Clin Pract Urol 3:522-3. 2006
  2. ncbi Commentary: on the incidence of histological prostate cancer and the probable diagnosis of cases with tumours too small to produce symptoms or to attract attention on physical examination--the findings of Dr Arnold Rice Rich
    Jan Adolfsson
    Oncologic Centre, Karolinska University Hospital, CLINTEC, Karolinska Institute, Stockholm, Sweden
    Int J Epidemiol 36:285-7. 2007
  3. ncbi Clinical characteristics and primary treatment of prostate cancer in Sweden between 1996 and 2005
    Jan Adolfsson
    Oncological Centre, Karolinska University Hospital, CLINTEC, Karolinska Institute, Stockholm, Sweden
    Scand J Urol Nephrol 41:456-77. 2007
    ..The incidence of prostate cancer is rising rapidly in Sweden and there is a need to better understand the pattern of diagnosis, tumor characteristics and treatment...
  4. doi Watchful waiting and active surveillance: the current position
    Jan Adolfsson
    Oncological Centre, CLINTEC, Karolinska Institutet, Stockholm, Sweden
    BJU Int 102:10-4. 2008
  5. ncbi The 20-Yr outcome in patients with well- or moderately differentiated clinically localized prostate cancer diagnosed in the pre-PSA era: the prognostic value of tumour ploidy and comorbidity
    Jan Adolfsson
    Oncologic Center, CLINTEC, Karolinska Institute, Stockholm, Sweden
    Eur Urol 52:1028-35. 2007
    ..This observational cohort study describes the long-term outcome of patients with clinically localized prostate cancer managed with watchful waiting, the prognostic value of tumour ploidy, and the impact of comorbidity...
  6. doi Differences according to socioeconomic status in the management and mortality in men with high risk prostate cancer
    Anders Berglund
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur J Cancer 48:75-84. 2012
    ..Outcomes for many cancer forms are associated with socioeconomic status (SES).We investigated if SES was associated with management and mortality in men with high risk prostate cancer...
  7. ncbi Prognostic significance of homozygous deletions and multiple duplications at the CDKN2A (p16INK4a)/ARF (p14ARF) locus in urinary bladder cancer
    Petra J Berggren de Verdier
    Clinical Center Epidemiology, Department of Oncology Pathology, Karolinska University Hospital, Stockholm, Sweden
    Scand J Urol Nephrol 40:363-9. 2006
    ..We studied how homozygous deletions and multiple duplications at this locus affect prognosis and survival in patients with bladder cancer...
  8. ncbi A single-nucleotide polymorphism in the XPG gene, and tumour stage, grade, and clinical course in patients with nonmuscle-invasive neoplasms of the urinary bladder
    Shigeru Sakano
    Department of Biosciences at Novum, Karolinska Institutet, Huddinge, Sweden
    BJU Int 97:847-51. 2006
    ....
  9. ncbi A population-based study of 538 patients with newly detected urinary bladder neoplasms followed during 5 years
    Per Larsson
    Clinical Cancer Epidemiology, Department of Oncology Pathology, Karolinska Institute, Stockholm, Sweden
    Scand J Urol Nephrol 37:195-201. 2003
    ..To describe in detail the diagnosis and clinical course of an unselected population-based cohort of patients with newly diagnosed bladder neoplasms...
  10. ncbi Prostate-specific antigen levels as a predictor of lethal prostate cancer
    Katja Fall
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
    J Natl Cancer Inst 99:526-32. 2007
    ..Rates of long-term survival among patients with untreated localized prostate cancer are high. To avoid unnecessary treatment, tools are needed to identify the small proportion of patients who are destined to develop lethal prostate cancer...
  11. doi Incidence of fractures causing hospitalisation in prostate cancer patients: results from the population-based PCBaSe Sweden
    Andreas Thorstenson
    Regional Cancer Centre, Karolinska University Hospital, Stockholm, Sweden
    Eur J Cancer 48:1672-81. 2012
    ..Data on incidence of fractures and risks in subgroups of men with prostate cancer are sparse. Our aim with this study is to report the risk of fractures among men with prostate cancer in a nationwide population-based study...
  12. ncbi Cohort Profile: the National Prostate Cancer Register of Sweden and Prostate Cancer data Base Sweden 2.0
    Mieke Van Hemelrijck
    King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, UK, Regional Cancer Centre, Uppsala University Hospital, Uppsala, Sweden, Department of Nursing, Umea University, Umea, Sweden, Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Oncological Centre, CLINTEC Department, Karolinska Institutet, Stockholm, Sweden, Deparment of Urology, Linkoping University Hospital, Linkoping, Sweden, Department of Urology, Orebro University Hospital and Orebro University, Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea University, Umea, Sweden and Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Int J Epidemiol 42:956-67. 2013
    ..7%. The NPCR is used to assess trends in incidence, treatment and outcome of men with PCa. Since the national registers linked to PCBaSe are complete, studies from PCBaSe 2.0 are truly population based. ..
  13. doi Impact of comorbidity on management and mortality in women diagnosed with breast cancer
    Anders Berglund
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, 171 77 Stockholm, Sweden
    Breast Cancer Res Treat 135:281-9. 2012
    ..The observed differences in breast cancer-specific mortality may be due to less extensive treatment, impaired tumor defense and differences in general health status and lifestyle factors...
  14. doi Mortality among men with locally advanced prostate cancer managed with noncurative intent: a nationwide study in PCBaSe Sweden
    Olof Akre
    Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 60:554-63. 2011
    ..There are limited prognostic data for locally advanced prostate cancer PCa to guide in the choice of treatment...
  15. ncbi Concordance of tumor differentiation among brothers with prostate cancer
    K Fredrik Jansson
    Urology Unit, Department of Surgery and Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 62:656-61. 2012
    ..Genetic factors seem to be of greater importance in prostate cancer than in other forms of cancer. Studies have suggested familial concordance in survival, but the extent to which that is due to tumor characteristics is not known...
  16. doi Y chromosome haplotypes and prostate cancer in Sweden
    Sara Lindstrom
    Department of Medical Epidemiology and Biostatistics and Oncologic Center, Karolinska Institutet, Stockholm, Sweden
    Clin Cancer Res 14:6712-6. 2008
    ..Certain Y-chromosomal lineages have been suggested to predispose individuals to prostate cancer in the Japanese population; in other ethnic groups, however, the importance of the Y chromosome is poorly understood...
  17. ncbi Need for and access to bereavement support after loss of a husband to urologic cancers: a nationwide follow-up of Swedish widows
    Unnur Valdimarsdottir
    Department of Medical Epidemiology and Biostatics, Karolinska Institutet, Stockholm, Sweden
    Scand J Urol Nephrol 39:271-6. 2005
    ..We investigated the prevalence and predictors of access to bereavement interventions during the first 6 months after the loss of a husband/male partner to prostate or urinary bladder cancer...
  18. ncbi A population-based assessment of germline HOXB13 G84E mutation and prostate cancer risk
    Robert Karlsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Electronic address
    Eur Urol 65:169-76. 2014
    ..A rare but recurrent missense mutation (G84E, rs138213197) in the gene homeobox B13 (HOXB13) was recently reported to be associated with hereditary prostate cancer...
  19. ncbi Incidence and prognosis of synchronous and metachronous bilateral breast cancer
    Mikael Hartman
    Department of Medical Epidemiology and Biostatistics, Stockholm Söder Hospital and Oncologic Center, CLINTEC, Stockholm, Sweden
    J Clin Oncol 25:4210-6. 2007
    ..Little is known, however, about incidence trends and prognostic features of bilateral breast cancer...
  20. doi The Nordic Nutrition Recommendations and prostate cancer risk in the Cancer of the Prostate in Sweden (CAPS) study
    Elisabeth Möller
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, SE 171 77 Stockholm, Sweden
    Public Health Nutr 15:1897-908. 2012
    ..We evaluated adherence to the NNR in relation to prostate cancer (PC) in Swedish men, including potential interaction with a genetic risk score and with lifestyle factors...
  21. doi Age-specific trends of survival in metastatic breast cancer: 26 years longitudinal data from a population-based cancer registry in Stockholm, Sweden
    Theodoros Foukakis
    Department of Oncology Pathology, Radiumhemmet, Karolinska Institutet, Karolinska University Hospital, 17176 Stockholm, Sweden
    Breast Cancer Res Treat 130:553-60. 2011
    ..Treatment advancements in MBC are not reflected by better survival for the whole MBC population. An improvement is only observed after the year 2000 and is restricted to younger patients...
  22. ncbi Disseminating evidence from health technology assessment: the case of tobacco prevention
    Susanna Axelsson
    The Swedish Council on Technology Assessment in Health Care, Stockholm, Sweden
    Int J Technol Assess Health Care 22:500-5. 2006
    ..The aims of the present study were to investigate the awareness among dentists and dental hygienists of evidence-based reports and guidelines on tobacco cessation activities and the impact these publications had on clinical practice...
  23. pmc Association of reported prostate cancer risk alleles with PSA levels among men without a diagnosis of prostate cancer
    Fredrik Wiklund
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Prostate 69:419-27. 2009
    ..Prostate specific antigen (PSA) is widely used for prostate cancer screening but its levels are influenced by many non cancer-related factors. The goal of the study is to estimate the effect of genetic variants on PSA levels...
  24. ncbi The choice between a therapy-induced long-term symptom and shortened survival due to prostate cancer
    Thomas Hopfgarten
    Division of Clinical Cancer Epidemiology, Department of Oncology Pathology, Radiumhemmet, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 50:280-9. 2006
    ..A patient with newly diagnosed localized prostate cancer can choose from an array of therapies. A patient's willingness to trade life for freedom from therapy-induced long-term symptoms is poorly investigated...
  25. doi How can we make cancer survival statistics more useful for patients and clinicians: an illustration using localized prostate cancer in Sweden
    Sandra Eloranta
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden
    Cancer Causes Control 24:505-15. 2013
    ..In this paper, we discuss the relative merits of recently developed alternatives to traditionally reported measures of cancer patient survival...
  26. pmc Mortality following Hip Fracture in Men with Prostate Cancer
    Mieke Van Hemelrijck
    King s College London, School of Medicine, Division of Cancer Studies, Cancer Epidemiology Group, London, United Kingdom Institute for Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 8:e74492. 2013
    ..Hip fractures are associated with increased mortality and are a known adverse effect of androgen deprivation therapy (ADT) for prostate cancer (PCa). It was our aim to evaluate how mortality after hip fracture is modified by PCa and ADT...
  27. ncbi Awareness of husband's impending death from cancer and long-term anxiety in widowhood: a nationwide follow-up
    Unnur Valdimarsdottir
    Unnur Valdimarsdóttir Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden
    Palliat Med 18:432-43. 2004
    ..We investigated the predictors and long-term consequences of awareness time - the length of time a woman is aware of her husband's impending death from cancer...
  28. doi Placental weight and mortality in premenopausal breast cancer by tumor characteristics
    Mohammad Hossein Hajiebrahimi
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden
    Breast Cancer Res Treat 137:297-305. 2013
    ..The increased mortality risk in premenopausal breast cancer associated with higher placental weight was most pronounced among ER(-) and PR(-) tumors...
  29. doi Prognosis of patients with breast cancer: causes of death and effects of time since diagnosis, age, and tumor characteristics
    Edoardo Colzani
    Department of Medical Epidemiology and Biostatistics MEB, Karolinska Institutet, Stockholm, Sweden
    J Clin Oncol 29:4014-21. 2011
    ..Because breast cancer-specific deaths decrease with time since diagnosis, it is important to assess the burden of other causes of death in women diagnosed with breast cancer...
  30. doi Polygenic risk score improves prostate cancer risk prediction: results from the Stockholm-1 cohort study
    Markus Aly
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Eur Urol 60:21-8. 2011
    ..The low specificity of prostate-specific antigen (PSA) results in diagnostic biopsies in men without prostate cancer (PCa). Additional information, such as genetic markers, could be used to avoid unnecessary biopsies...
  31. ncbi Reliability of assessment of urgency and other symptoms indicating anal sphincter, large bowel or urinary dysfunction
    Massoud al-Abany
    Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden
    Scand J Urol Nephrol 40:397-408. 2006
    ..However, no test-retest reliability study of it has been conducted concerning the assessment of urinary, anal sphincter or large bowel function. The aim of this study was to evaluate the reliability of items assessing these functions...
  32. doi Alcohol influence on acrylamide to glycidamide metabolism assessed with hemoglobin-adducts and questionnaire data
    Anna C Vikström
    Department of Materials and Environmental Chemistry, Stockholm University, Stockholm, Sweden
    Food Chem Toxicol 48:820-4. 2010
    ....
  33. ncbi Bladder neoplasms--regions at chromosome 9 with putative tumour suppressor genes
    Takashi Wada
    Department of Biosciences at Novum, Karolinska Institute, SE 171 76 Stockholm, Sweden
    Scand J Urol Nephrol 37:106-11. 2003
    ..To investigate the prevalence of loss of heterozygosity (LOH) at 12 different loci on chromosome 9 in patients with bladder neoplasms using a newly developed fluorescent multiplex polymerase chain reaction...
  34. ncbi Long-term effects of widowhood after terminal cancer: a Swedish nationwide follow-up
    Unnur Valdimarsdottir
    Department of Clinical Cancer Epidemiology, Institute of Oncology Pathology, Karolinska Institute, Box 4402, 10268 Stockholm, Sweden
    Scand J Public Health 31:31-6. 2003
    ..The authors investigated whether becoming a widow after the death of a husband from cancer results in long-term psychological or physical morbidity...
  35. ncbi Birth size in the most recent pregnancy and maternal mortality in premenopausal breast cancer by tumor characteristics
    Mohammadhossein Hajiebrahimi
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, 171 76, Stockholm, Sweden
    Breast Cancer Res Treat 145:471-80. 2014
    ..In addition, these associations are not modified by tumor characteristics. ..
  36. doi Prostate-specific antigen (PSA) testing is prevalent and increasing in Stockholm County, Sweden, Despite no recommendations for PSA screening: results from a population-based study, 2003-2011
    Tobias Nordström
    Department of Clinical Sciences at Danderyds Hospital, Karolinska Institutet, Stockholm, Sweden
    Eur Urol 63:419-25. 2013
    ..Prostate-specific antigen (PSA) testing has increased in several countries. There is incomplete knowledge of PSA testing patterns...
  37. ncbi Hip fractures in men with prostate cancer treated with orchiectomy
    Paul W Dickman
    Department of Oncology, Karolinska Institutet, Stockholm, Sweden
    J Urol 172:2208-12. 2004
    ..Data directly addressing the long-term fracture risk in men diagnosed with prostate cancer are limited...
  38. ncbi Clinical course of bladder neoplasms and single nucleotide polymorphisms in the CDKN2A gene
    Shigeru Sakano
    Department of Biosciences, Karolinska Institute, Huddinge, Sweden
    Int J Cancer 104:98-103. 2003
    ..Further, the results indicate, a role for the 3' UTR polymorphisms in the CDKN2A gene in tumor invasiveness...
  39. ncbi The Internet and prostate cancer patients: searching for and finding information
    Stefan Buntrock
    Division of Clinical Cancer Epidemiology, Karolinska Institute, Stockholm, Sweden
    Scand J Urol Nephrol 41:367-74. 2007
    ..To define the characteristics of prostate cancer patients who use the Internet...
  40. ncbi Health-related quality-of-life assessments in patients with advanced cancer of the prostate
    Jan Adolfsson
    Center for Surgical Sciences, Karolinska Institute, Stockholm, Sweden
    Pharmacoeconomics 21:241-7. 2003
    ..Also, we need an increased understanding of the mechanisms behind patients' trade-offs and of how information should be communicated to patients in order to give the best possibilities for making informed treatment decisions...
  41. ncbi Association of frequent consumption of fatty fish with prostate cancer risk is modified by COX-2 polymorphism
    Maria Hedelin
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Int J Cancer 120:398-405. 2007
    ..Frequent consumption of fatty fish and marine fatty acids appears to reduce the risk of prostate cancer, and this association is modified by genetic variation in the COX-2 gene...
  42. doi Reductions in use of hormone replacement therapy: effects on Swedish breast cancer incidence trends only seen after several years
    Mats Lambe
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, 171 77 Stockholm, Sweden
    Breast Cancer Res Treat 121:679-83. 2010
    ..The present findings give further support to the notion that HRT use is a driver of breast cancer incidence trends on the population level...
  43. ncbi A hierarchical step-model for causation of bias-evaluating cancer treatment with epidemiological methods
    Gunnar Steineck
    Division of Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden
    Acta Oncol 45:421-9. 2006
    ..Acceptance of this model has implications for ascertaining the degree to which a study effectively evaluates the effects of cancer treatment (level of scientific evidence)...
  44. ncbi Tobacco prevention in Swedish dental care
    Asgeir R Helgason
    Stockholm Center of Public Health, Center for Tobacco Prevention, Karolinska Institute, Stockholm, Sweden
    Community Dent Oral Epidemiol 31:378-85. 2003
    ..To assess tobacco prevention in Swedish dental care and to identify barriers. Also, to investigate whether dentists and dental hygienists were familiar with recently published review of smoking cessation methods...
  45. ncbi Tumour characteristics and surgical treatment of renal cell carcinoma in Sweden 2005-2010: a population-based study from the National Swedish Kidney Cancer Register
    Andreas Thorstenson
    Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institute, Stockholm, Sweden
    Scand J Urol 48:231-8. 2014
    ..Between 2005 and 2010, 5553 RCC patients were registered in the NSKCR, 99% of those registered in the National Cancer Registry...
  46. doi Quality indicators for palliative and end of life care: a review of Swedish policy documents
    Susanne Lind
    Palliative Research Centre, Ersta Sköndal University College and Ersta Hospital, Stockholm, Sweden
    BMJ Support Palliat Care 3:174-80. 2013
    ..The aim of this paper was to review existing quality indicators in national Swedish policy documents relevant to palliative and end of life care...
  47. ncbi Quality of life after radical prostatectomy or watchful waiting
    Gunnar Steineck
    Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden
    N Engl J Med 347:790-6. 2002
    ..We evaluated symptoms and self-assessments of quality of life in men with localized prostate cancer who participated in a randomized comparison between radical prostatectomy and watchful waiting...
  48. ncbi Economic conditions and marriage quality of men with prostate cancer
    Lizzy Sunny
    Division of Clinical Cancer Epidemiology, Department of Oncology, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden
    BJU Int 99:1391-7. 2007
    ....
  49. ncbi The National Prostate Cancer Register in Sweden 1998-2002: trends in incidence, treatment and survival
    Eberhard Varenhorst
    Department of Urology, Faculty of Health Sciences, University Hospital Linkoping, Linkoping, Sweden
    Scand J Urol Nephrol 39:117-23. 2005
    ..To provide a descriptive review of the establishment of the National Prostate Cancer Register (NPCR) in Sweden, to present clinical characteristics at diagnosis and to calculate the relative survival of different risk groups after 5 years...
  50. ncbi Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden
    Cancer Res 66:11077-83. 2006
    ..Carriers of five high-risk alleles in the AR, CYP17, and SRD5A2 genes are at approximately 2-fold excess risk to develop prostate cancer...
  51. ncbi Comprehensive genetic evaluation of common E-cadherin sequence variants and prostate cancer risk: strong confirmation of functional promoter SNP
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, University of Umea, 901 87, Umea, Sweden
    Hum Genet 118:339-47. 2005
    ..Due to the difficulties in replication of genetic association studies, this finding is unusual and novel...
  52. ncbi Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, University of Umea, Umea, Sweden
    Prostate 66:1729-43. 2006
    ..Despite considerable efforts and initial promising findings, the field of prostate cancer genetics is characterized by inconclusive reports and no prostate cancer gene has yet been established...
  53. doi Predictors for the symptomatic prostate cancer patient's delays in seeking care
    Lizzy Sunny
    Division of Clinical Cancer Epidemiology, Department of Oncology, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden
    Eur J Cancer 44:733-9. 2008
    ..This study aims to determine the predictors for the symptomatic prostate cancer patient's delays in seeking care...
  54. ncbi The management of category T1a-T1b (incidental) prostate cancer: can we predict who needs treatment?
    Jan Adolfsson
    Eur Urol 54:16-8. 2008
  55. pmc Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12
    Jielin Sun
    Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Nat Genet 40:1153-5. 2008
    ..7 x 10(-9) for an allelic test of the seven studies combined. The association at each SNP remained significant after adjustment for the other SNP...
  56. ncbi Interleukin-6 sequence variants are not associated with prostate cancer risk
    Jielin Sun
    Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Cancer Epidemiol Biomarkers Prev 13:1677-9. 2004
  57. ncbi Genetic analysis of the RNASEL gene in hereditary, familial, and sporadic prostate cancer
    Fredrik Wiklund
    Department of Radiation Sciences, Oncology, and Medical Biosciences, Pathology, University of Umea, Umea, Sweden
    Clin Cancer Res 10:7150-6. 2004
    ..To additionally evaluate the possible role of RNASEL in susceptibility to prostate cancer risk, we performed a comprehensive genetic analysis of sequence variants in RNASEL in the Swedish population...