Affiliation: Karo Bio AB
- The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonismBjörn Kauppi
Structure Biology, Karo Bio AB, Novum, SE 141 57 Huddinge, Sweden
J Biol Chem 278:22748-54. 2003..All three RU-486 GR-LBD structures show that GR has a very flexible region between the end of helix 11 and the end of helix 12...