Research Topics
| Ulrika BroomeSummaryAffiliation: Huddinge University Hospital Country: Sweden Publications
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Detail Information
Publications
Primary sclerosing cholangitis, inflammatory bowel disease, and colon cancerUlrika Broome
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
Semin Liver Dis 26:31-41. 2006..In patients having an ileal pelvic pouch with ileal anal anastomosis, PSC is a risk factor for development of pouchitis. It is important that all PSC patients with UC are included in colonoscopic surveillance programs...
Natural history and outcome in 32 Swedish patients with small duct primary sclerosing cholangitis (PSC)Ulrika Broome
Department of Gastroenterology, Huddinge University Hospital, Stockholm, Sweden
J Hepatol 36:586-9. 2002..This study aims at describing the natural history and outcome of small duct primary sclerosing cholangitis (PSC)...
Management of primary sclerosing cholangitis and its complications in adult patientsUlrika Broome
Department of Gastroenterology and Hepatology, K63, Huddinge University Hospital, 141 86 Huddinge, Sweden
Acta Gastroenterol Belg 65:37-44. 2002
Changes over a 20-year period in the clinical presentation of primary sclerosing cholangitis in SwedenAnnika Bergquist
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, Sweden
Scand J Gastroenterol 42:88-93. 2007..The aim of this study was to investigate the clinical presentation of PSC including its association with inflammatory bowel disease (IBD) and the development of cholangiocarcinoma at one centre over an observation period of 20 years...
Perinatal events and the risk of developing primary sclerosing cholangitisAnnika Bergquist
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Sweden
World J Gastroenterol 12:6037-40. 2006..To investigate whether perinatal events, intrauterine or postpartum, are associated with the development of primary sclerosing cholangitis (PSC) later in life...
Hepatic and extrahepatic malignancies in primary sclerosing cholangitisAnnika Bergquist
Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institute, Huddinge, 141 86, Stockholm, Sweden
J Hepatol 36:321-7. 2002..To assess the risk of hepatic and extrahepatic malignancies in a large cohort of Swedish primary sclerosing cholangitis (PSC) patients compared with that of the general Swedish population...
Living-related liver transplantation in children--a single center evaluation of the outcome of donor candidates and recipientsBjorn Fischler
Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
Pediatr Transplant 12:531-5. 2008..The fact that parents of BA patients have potential liver pathology may be of importance for the understanding of the etiology of the disease and have possible implications for the choice of donors...
Dynamic FDG-PET is useful for detection of cholangiocarcinoma in patients with PSC listed for liver transplantationHanne Prytz
Department of Gastroenterology, University Hospital of Lund, Lund, Sweden
Hepatology 44:1572-80. 2006..In conclusion, dynamic FDG-PET appears superior to conventional imaging techniques for both detection and exclusion of CC in advanced PSC. FDG-PET may be useful for screening for CC in the pretransplant evaluation of patients with PSC...
Atrophy and neoplastic transformation of the ileal pouch mucosa in patients with ulcerative colitis and primary sclerosing cholangitis: a case control studyDagny Ståhlberg
Department of Gastroenterology at St Göran s Hospital, Stockholm, Sweden
Dis Colon Rectum 46:770-8. 2003..Patients with ulcerative colitis and primary sclerosing cholangitis have an increased risk of developing carcinoma both in the bile ducts and in the colon...
Primary sclerosing cholangitis can present with acute liver failure: Report of two casesAnnika Bergquist
Department of Gastroenterology, Karolinska University Hospital, Huddinge, Karolinska Institute, Stockholm
J Hepatol 44:1005-8. 2006..The aim of the present study was to determine whether PSC can present with acute liver failure (ALF) and to determine its frequency...
A prospective, randomized, multi-centre trial of systemic adjuvant chemotherapy versus no additional treatment in liver transplantation for hepatocellular carcinomaGunnar Soderdahl
Department of Transplantation Surgery, Karolinska University Hospital, Huddinge, Stockholm, Sweden
Transpl Int 19:288-94. 2006..None of the differences was statistically significant. Neoadjuvant treatment with systemic low-dose doxorubicin seems not to improve either survival or freedom from recurrence in patients with HCC undergoing LT...
Biliary epithelial cell antibodies link adaptive and innate immune responses in primary sclerosing cholangitisAzza Karrar
Division of Transplantation Surgery, Division of Clinical Immunology, Karolinska University Hospital Huddinge, Stockholm, Sweden
Gastroenterology 132:1504-14. 2007..A high frequency of biliary epithelial cell antibodies (BEC-Ab) is present in PSC. Here, we studied the mechanisms and signaling pathways used by these Ab in causing BEC dysfunction...
Increased prevalence of primary sclerosing cholangitis among first-degree relativesAnnika Bergquist
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, 141 86 Huddinge, Sweden
J Hepatol 42:252-6. 2005..The aim of the present study was to investigate the familial occurrence of autoimmune diseases in a large group of patients with primary sclerosing cholangitis (PSC)...
A novel mechanism of liver allograft rejection facilitated by antibodies to liver sinusoidal endothelial cellsSuchitra Sumitran-Holgersson
Department of Transplantation Surgery, Karolinska University Hospital Huddinge, Karolinska Institute, Stockholm, Sweden
Hepatology 40:1211-21. 2004..In conclusion, antibodies to LSECs may facilitate acute liver allograft rejections by down-regulating the immune modulating cytokine TGF-beta and thus up-regulating alloreactive T-cell proliferation...
Are preformed antibodies to biliary epithelial cells of clinical importance in liver transplantation?Xupeng Ge
Department of Transplantation Surgery, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden
Liver Transpl 9:1191-8. 2003..In conclusion, preformed antibodies to BECs are associated with acute rejection. Thus, the presence of these antibodies before transplantation may facilitate acute liver graft rejection...
