Annika Bergquist

Summary

Affiliation: Huddinge University Hospital
Country: Sweden

Publications

  1. ncbi Can DNA cytometry be used for evaluation of malignancy and premalignancy in bile duct strictures in primary sclerosing cholangitis?
    A Bergquist
    Department of Gastroenterology and Hepatology, Karolinska Institute, Huddinge, Sweden
    J Hepatol 33:873-7. 2000
  2. ncbi Biliary dysplasia, cell proliferation and nuclear DNA-fragmentation in primary sclerosing cholangitis with and without cholangiocarcinoma
    A Bergquist
    Department of Gastroenterology and Hepatology, Huddinge University Hospital, Huddinge, Sweden
    J Intern Med 249:69-75. 2001
  3. ncbi Methodologic aspects of evaluating brush samples from biliary strictures by cytology and DNA flow cytometry
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    Acta Cytol 48:341-7. 2004
  4. ncbi Increased prevalence of primary sclerosing cholangitis among first-degree relatives
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, 141 86 Huddinge, Sweden
    J Hepatol 42:252-6. 2005
  5. doi Increased risk of primary sclerosing cholangitis and ulcerative colitis in first-degree relatives of patients with primary sclerosing cholangitis
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institute, Huddinge and Solna, Stockholm, Sweden
    Clin Gastroenterol Hepatol 6:939-43. 2008
  6. doi The value of thioredoxin family proteins and proliferation markers in dysplastic and malignant gallbladders in patients with primary sclerosing cholangitis
    Karouk Said
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institutet, 141 86 Stockholm, Sweden
    Dig Dis Sci 57:1163-70. 2012
  7. doi Gallbladder disease in patients with primary sclerosing cholangitis
    Karouk Said
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institute, 141 86 Stockholm, Sweden
    J Hepatol 48:598-605. 2008
  8. ncbi Changes over a 20-year period in the clinical presentation of primary sclerosing cholangitis in Sweden
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, Sweden
    Scand J Gastroenterol 42:88-93. 2007
  9. ncbi The international normalized ratio according to Owren in liver disease: interlaboratory assessment and determination of international sensitivity index
    Maria Magnusson
    CLINTEC, Karolinska Institutet, Division of Pediatrics, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden Electronic address
    Thromb Res 132:346-51. 2013
  10. doi Pancreatic duct changes are not associated with early signs of chronic pancreatitis at magnetic resonance imaging (MRI) in patients with primary sclerosing cholangitis
    Karouk Said
    Division of Gastroenterology and Hepatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Scand J Gastroenterol 45:980-6. 2010

Detail Information

Publications35

  1. ncbi Can DNA cytometry be used for evaluation of malignancy and premalignancy in bile duct strictures in primary sclerosing cholangitis?
    A Bergquist
    Department of Gastroenterology and Hepatology, Karolinska Institute, Huddinge, Sweden
    J Hepatol 33:873-7. 2000
    ..Knowledge of tumour cell ploidy by DNA cytometry may facilitate the evaluation of malignant and premalignant lesions in PSC...
  2. ncbi Biliary dysplasia, cell proliferation and nuclear DNA-fragmentation in primary sclerosing cholangitis with and without cholangiocarcinoma
    A Bergquist
    Department of Gastroenterology and Hepatology, Huddinge University Hospital, Huddinge, Sweden
    J Intern Med 249:69-75. 2001
    ..To study the extent of biliary dysplasia, and the degree of cell proliferation and apoptosis in bile duct cells (BDC) from patients with primary sclerosing cholangitis (PSC), with and without cholangiocarcinoma (CC)...
  3. ncbi Methodologic aspects of evaluating brush samples from biliary strictures by cytology and DNA flow cytometry
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    Acta Cytol 48:341-7. 2004
    ..To present a method of increasing the cell yield from brush samples of the biliary tree for measurement of DNA content by flow cytometry (FCM)...
  4. ncbi Increased prevalence of primary sclerosing cholangitis among first-degree relatives
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, 141 86 Huddinge, Sweden
    J Hepatol 42:252-6. 2005
    ..The aim of the present study was to investigate the familial occurrence of autoimmune diseases in a large group of patients with primary sclerosing cholangitis (PSC)...
  5. doi Increased risk of primary sclerosing cholangitis and ulcerative colitis in first-degree relatives of patients with primary sclerosing cholangitis
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institute, Huddinge and Solna, Stockholm, Sweden
    Clin Gastroenterol Hepatol 6:939-43. 2008
    ..This study assessed the risk of PSC and inflammatory bowel disease (IBD) among first-degree relatives of patients with PSC, compared with the first-degree relatives of a cohort without PSC...
  6. doi The value of thioredoxin family proteins and proliferation markers in dysplastic and malignant gallbladders in patients with primary sclerosing cholangitis
    Karouk Said
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institutet, 141 86 Stockholm, Sweden
    Dig Dis Sci 57:1163-70. 2012
    ..Patients with primary sclerosing cholangitis (PSC) have an increased risk for biliary and gallbladder malignancy and markers of early malignancy in PSC are lacking. The aims were to evaluate biomarkers to look for premalignancy/malignancy...
  7. doi Gallbladder disease in patients with primary sclerosing cholangitis
    Karouk Said
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institute, 141 86 Stockholm, Sweden
    J Hepatol 48:598-605. 2008
    ..Gallbladder abnormalities may be part of the spectrum in primary sclerosing cholangitis (PSC). The aim of the present study was to evaluate the occurrence and prognostic importance of gallbladder abnormalities in patients with PSC...
  8. ncbi Changes over a 20-year period in the clinical presentation of primary sclerosing cholangitis in Sweden
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, Sweden
    Scand J Gastroenterol 42:88-93. 2007
    ..The aim of this study was to investigate the clinical presentation of PSC including its association with inflammatory bowel disease (IBD) and the development of cholangiocarcinoma at one centre over an observation period of 20 years...
  9. ncbi The international normalized ratio according to Owren in liver disease: interlaboratory assessment and determination of international sensitivity index
    Maria Magnusson
    CLINTEC, Karolinska Institutet, Division of Pediatrics, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden Electronic address
    Thromb Res 132:346-51. 2013
    ..Further, we determined the difference between international sensitivity index (ISI) for patients on vitamin K antagonists (ISIVKA) and ISI for patients with liver disease (ISIliver)...
  10. doi Pancreatic duct changes are not associated with early signs of chronic pancreatitis at magnetic resonance imaging (MRI) in patients with primary sclerosing cholangitis
    Karouk Said
    Division of Gastroenterology and Hepatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Scand J Gastroenterol 45:980-6. 2010
    ..The aims of the present study were to evaluate the presence of early pancreatic abnormalities and duct changes, using MRCP/MRI in PSC and to evaluate possible risk factors for these changes and their clinical importance...
  11. doi Primary sclerosing cholangitis is associated with autoreactive IgA antibodies against biliary epithelial cells
    Lena Berglin
    Liver Immunology Laboratory, Unit of Gastroenterology and Hepatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Scand J Gastroenterol 48:719-28. 2013
    ..The aim of this study was to evaluate the presence of autoreactive IgA in PSC patients...
  12. doi Association between reduced levels of alkaline phosphatase and survival times of patients with primary sclerosing cholangitis
    Lina Lindström
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Stockholm, Sweden
    Clin Gastroenterol Hepatol 11:841-6. 2013
    ..We compared survival times between patients with PSC treated with UDCA or placebo, with and without decreased levels of ALP...
  13. ncbi Biliary epithelial cell antibodies link adaptive and innate immune responses in primary sclerosing cholangitis
    Azza Karrar
    Division of Transplantation Surgery, Division of Clinical Immunology, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Gastroenterology 132:1504-14. 2007
    ..A high frequency of biliary epithelial cell antibodies (BEC-Ab) is present in PSC. Here, we studied the mechanisms and signaling pathways used by these Ab in causing BEC dysfunction...
  14. ncbi Hepatic and extrahepatic malignancies in primary sclerosing cholangitis
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institute, Huddinge, 141 86, Stockholm, Sweden
    J Hepatol 36:321-7. 2002
    ..To assess the risk of hepatic and extrahepatic malignancies in a large cohort of Swedish primary sclerosing cholangitis (PSC) patients compared with that of the general Swedish population...
  15. ncbi Diagnosis of biliary strictures in conjunction with endoscopic retrograde cholangiopancreaticography, with special reference to patients with primary sclerosing cholangitis
    B Lindberg
    Department of Radiology, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden
    Endoscopy 34:909-16. 2002
    ..The aim of this study was to evaluate diagnostic methods for malignancy in biliary strictures in conjunction with endoscopic retrograde cholangiopancreaticography (ERCP)...
  16. ncbi Manganese chloride tetrahydrate (CMC-001) enhanced liver MRI: evaluation of efficacy and safety in healthy volunteers
    Nils Albiin
    Department of Clinical Science, Intervention and Technology CLINTEC, Division of Medical Imaging and Technology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    MAGMA 25:361-8. 2012
    ..To evaluate the efficacy of three dose levels of the oral hepatobiliary manganese-based magnetic resonance imaging (MRI) contrast agent CMC-001, and assess its safety profile and patient acceptability...
  17. ncbi Primary sclerosing cholangitis can present with acute liver failure: Report of two cases
    Annika Bergquist
    Department of Gastroenterology, Karolinska University Hospital, Huddinge, Karolinska Institute, Stockholm
    J Hepatol 44:1005-8. 2006
    ..The aim of the present study was to determine whether PSC can present with acute liver failure (ALF) and to determine its frequency...
  18. ncbi Diagnostic and prognostic implications of DNA ploidy and S-phase evaluation in the assessment of malignancy in biliary strictures
    B Lindberg
    Department of Radiology, Karolinska University Hospital, Karolinska Institutet, Sweden
    Endoscopy 38:561-5. 2006
    ..The aim of the present study was to assess the diagnostic and prognostic importance of DNA measurements as an adjunct to brush cytology in patients with biliary strictures...
  19. ncbi Hepatobiliary and extra-hepatic malignancies in primary sclerosing cholangitis
    A Bergquist
    Department of Gastroenterology and Hepatology, Karolinska Institute, Huddinge University Hospital, K 63, Stockholm, S-141 86, Sweden
    Best Pract Res Clin Gastroenterol 15:643-56. 2001
    ..Therefore, it is of great importance to identify PSC patients who are at risk of developing cholangiocarcinoma in order to transplant them before cancer has developed...
  20. doi Detection of cholangiocarcinoma with magnetic resonance spectroscopy of bile in patients with and without primary sclerosing cholangitis
    N Albiin
    Division of Radiology, Department for Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden
    Acta Radiol 49:855-62. 2008
    ..Early detection of cholangiocarcinoma (CC) is very difficult, especially in patients with primary sclerosing cholangitis (PSC) who are at increased risk of developing CC...
  21. pmc Alcohol consumption in patients with primary sclerosing cholangitis
    Hannes Hagström
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institutet, 14186 Stockholm, Sweden
    World J Gastroenterol 18:3105-11. 2012
    ..To assess the alcohol drinking patterns in a cohort of primary sclerosing cholangitis (PSC) patients and the possible influence on the development of fibrosis...
  22. pmc Gallbladder emptying in patients with primary sclerosing cholangitis
    Karouk Said
    Department of Gastroenterology and Hepatology, Karolinska Institute, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
    World J Gastroenterol 15:3498-503. 2009
    ..To assess gallbladder emptying and its association with cholecystitis and abdominal pain in patients with primary sclerosing cholangitis (PSC)...
  23. doi Increased risk of colorectal cancer and dysplasia in patients with Crohn's colitis and primary sclerosing cholangitis
    Lina Lindström
    Division of Gastroenterology and Hepatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Dis Colon Rectum 54:1392-7. 2011
    ..Clinical characteristics and the risk of colon cancer or dysplasia in Crohn's disease and primary sclerosing cholangitis are less well examined than in ulcerative colitis...
  24. ncbi Primary sclerosing cholangitis, inflammatory bowel disease, and colon cancer
    Ulrika Broome
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
    Semin Liver Dis 26:31-41. 2006
    ..In patients having an ileal pelvic pouch with ileal anal anastomosis, PSC is a risk factor for development of pouchitis. It is important that all PSC patients with UC are included in colonoscopic surveillance programs...
  25. ncbi Living-related liver transplantation in children--a single center evaluation of the outcome of donor candidates and recipients
    Bjorn Fischler
    Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Pediatr Transplant 12:531-5. 2008
    ..The fact that parents of BA patients have potential liver pathology may be of importance for the understanding of the etiology of the disease and have possible implications for the choice of donors...
  26. ncbi Perinatal events and the risk of developing primary sclerosing cholangitis
    Annika Bergquist
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Sweden
    World J Gastroenterol 12:6037-40. 2006
    ..To investigate whether perinatal events, intrauterine or postpartum, are associated with the development of primary sclerosing cholangitis (PSC) later in life...
  27. doi High dose ursodeoxycholic acid in primary sclerosing cholangitis does not prevent colorectal neoplasia
    L Lindstrom
    Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Aliment Pharmacol Ther 35:451-7. 2012
    ..Ursodeoxycholic acid (UDCA) has been suggested to have chemopreventive effects on the development of colorectal cancer and dysplasia but long-term data and larger trials are lacking...
  28. doi Liver transplantation of patients with cryptogenic cirrhosis: clinical characteristics and outcome
    Joel Marmur
    Department of Gastroenterology and Hepatology, Karolinska Institutet, Ersta Hospital, Stockholm, Sweden
    Scand J Gastroenterol 45:60-9. 2010
    ....
  29. ncbi Clinical features in primary sclerosing cholangitis
    A Bergquist
    Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institute, Huddinge, Sweden
    Clin Liver Dis 2:283-301, viii. 1998
    ..This article describes clinical features in primary sclerosing cholangitis, including clinical presentation and complications. The natural history of the disease is discussed, as well as the strong association to inflammatory bowel disease...
  30. ncbi [Acute liver failure--rapid multidisciplinary management]
    Einar Bjornsson
    Medicinkliniken, Gastrosektionen, Sahlgrenska Universitetssjukhuset, Goteborg
    Lakartidningen 104:210-3. 2007
  31. ncbi Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitis
    Tom H Karlsen
    Medical Department, Rikshospitalet Radiumhospitalet Medical Center, University of Oslo, Oslo, Norway
    J Hepatol 46:899-906. 2007
    ..We aimed to clarify to what extent such combinations influence susceptibility to primary sclerosing cholangitis (PSC)...
  32. ncbi Time-dependent Cox regression model is superior in prediction of prognosis in primary sclerosing cholangitis
    Kirsten Muri Boberg
    Medical Department, Rikshospitalet, 0027 Oslo, Norway
    Hepatology 35:652-7. 2002
    ..In conclusion, a time-dependent Cox regression model has the potential to estimate a more precise short-term prognosis in PSC compared with the traditional time-fixed models...
  33. doi The natural history of small-duct primary sclerosing cholangitis
    Einar Bjornsson
    Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
    Gastroenterology 134:975-80. 2008
    ..We aimed at determining the natural history and long-term outcomes of a large number of patients with small-duct PSC...
  34. doi An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitis
    Espen Melum
    Am J Gastroenterol 103:1045; author reply 1045-6. 2008
  35. ncbi Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms
    Espen Melum
    Medical Department, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    Hepatology 47:90-6. 2008
    ..31-3.29, corrected P (P(c)) = 0.011] and rs2617167 (OR = 2.32, 95% CI = 1.47-3.66, P(c) = 0.0020). Carriership of the MICA 5.1 allele was associated with resistance against CCA (OR = 0.43, 95% CI = 0.20-0.95, not corrected P = 0.032)...