Research Topics
| Annika BergquistSummaryAffiliation: Huddinge University Hospital Country: Sweden Publications
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Detail Information
Publications
Can DNA cytometry be used for evaluation of malignancy and premalignancy in bile duct strictures in primary sclerosing cholangitis?A Bergquist
Department of Gastroenterology and Hepatology, Karolinska Institute, Huddinge, Sweden
J Hepatol 33:873-7. 2000..Knowledge of tumour cell ploidy by DNA cytometry may facilitate the evaluation of malignant and premalignant lesions in PSC...- Biliary dysplasia, cell proliferation and nuclear DNA-fragmentation in primary sclerosing cholangitis with and without cholangiocarcinomaA Bergquist
Department of Gastroenterology and Hepatology, Huddinge University Hospital, Huddinge, Sweden
J Intern Med 249:69-75. 2001..To study the extent of biliary dysplasia, and the degree of cell proliferation and apoptosis in bile duct cells (BDC) from patients with primary sclerosing cholangitis (PSC), with and without cholangiocarcinoma (CC)... - Increased prevalence of primary sclerosing cholangitis among first-degree relativesAnnika Bergquist
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, 141 86 Huddinge, Sweden
J Hepatol 42:252-6. 2005..The aim of the present study was to investigate the familial occurrence of autoimmune diseases in a large group of patients with primary sclerosing cholangitis (PSC)... - Methodologic aspects of evaluating brush samples from biliary strictures by cytology and DNA flow cytometryAnnika Bergquist
Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
Acta Cytol 48:341-7. 2004..To present a method of increasing the cell yield from brush samples of the biliary tree for measurement of DNA content by flow cytometry (FCM)... 
Increased risk of primary sclerosing cholangitis and ulcerative colitis in first-degree relatives of patients with primary sclerosing cholangitisAnnika Bergquist
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institute, Huddinge and Solna, Stockholm, Sweden
Clin Gastroenterol Hepatol 6:939-43. 2008..This study assessed the risk of PSC and inflammatory bowel disease (IBD) among first-degree relatives of patients with PSC, compared with the first-degree relatives of a cohort without PSC...- The value of thioredoxin family proteins and proliferation markers in dysplastic and malignant gallbladders in patients with primary sclerosing cholangitisKarouk Said
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institutet, 141 86 Stockholm, Sweden
Dig Dis Sci 57:1163-70. 2012..Patients with primary sclerosing cholangitis (PSC) have an increased risk for biliary and gallbladder malignancy and markers of early malignancy in PSC are lacking. The aims were to evaluate biomarkers to look for premalignancy/malignancy... - Gallbladder disease in patients with primary sclerosing cholangitisKarouk Said
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institute, 141 86 Stockholm, Sweden
J Hepatol 48:598-605. 2008..Gallbladder abnormalities may be part of the spectrum in primary sclerosing cholangitis (PSC). The aim of the present study was to evaluate the occurrence and prognostic importance of gallbladder abnormalities in patients with PSC... - Changes over a 20-year period in the clinical presentation of primary sclerosing cholangitis in SwedenAnnika Bergquist
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Karolinska Institutet, Stockholm, Sweden
Scand J Gastroenterol 42:88-93. 2007..The aim of this study was to investigate the clinical presentation of PSC including its association with inflammatory bowel disease (IBD) and the development of cholangiocarcinoma at one centre over an observation period of 20 years... - Pancreatic duct changes are not associated with early signs of chronic pancreatitis at magnetic resonance imaging (MRI) in patients with primary sclerosing cholangitisKarouk Said
Division of Gastroenterology and Hepatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Scand J Gastroenterol 45:980-6. 2010..The aims of the present study were to evaluate the presence of early pancreatic abnormalities and duct changes, using MRCP/MRI in PSC and to evaluate possible risk factors for these changes and their clinical importance... - Biliary epithelial cell antibodies link adaptive and innate immune responses in primary sclerosing cholangitisAzza Karrar
Division of Transplantation Surgery, Division of Clinical Immunology, Karolinska University Hospital Huddinge, Stockholm, Sweden
Gastroenterology 132:1504-14. 2007..A high frequency of biliary epithelial cell antibodies (BEC-Ab) is present in PSC. Here, we studied the mechanisms and signaling pathways used by these Ab in causing BEC dysfunction... - Hepatic and extrahepatic malignancies in primary sclerosing cholangitisAnnika Bergquist
Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institute, Huddinge, 141 86, Stockholm, Sweden
J Hepatol 36:321-7. 2002..To assess the risk of hepatic and extrahepatic malignancies in a large cohort of Swedish primary sclerosing cholangitis (PSC) patients compared with that of the general Swedish population... - Diagnosis of biliary strictures in conjunction with endoscopic retrograde cholangiopancreaticography, with special reference to patients with primary sclerosing cholangitisB Lindberg
Department of Radiology, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden
Endoscopy 34:909-16. 2002..The aim of this study was to evaluate diagnostic methods for malignancy in biliary strictures in conjunction with endoscopic retrograde cholangiopancreaticography (ERCP)... - Manganese chloride tetrahydrate (CMC-001) enhanced liver MRI: evaluation of efficacy and safety in healthy volunteersNils Albiin
Department of Clinical Science, Intervention and Technology CLINTEC, Division of Medical Imaging and Technology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
MAGMA 25:361-8. 2012..To evaluate the efficacy of three dose levels of the oral hepatobiliary manganese-based magnetic resonance imaging (MRI) contrast agent CMC-001, and assess its safety profile and patient acceptability... - Primary sclerosing cholangitis can present with acute liver failure: Report of two casesAnnika Bergquist
Department of Gastroenterology, Karolinska University Hospital, Huddinge, Karolinska Institute, Stockholm
J Hepatol 44:1005-8. 2006..The aim of the present study was to determine whether PSC can present with acute liver failure (ALF) and to determine its frequency... - Hepatobiliary and extra-hepatic malignancies in primary sclerosing cholangitisA Bergquist
Department of Gastroenterology and Hepatology, Karolinska Institute, Huddinge University Hospital, K 63, Stockholm, S-141 86, Sweden
Best Pract Res Clin Gastroenterol 15:643-56. 2001..Therefore, it is of great importance to identify PSC patients who are at risk of developing cholangiocarcinoma in order to transplant them before cancer has developed... - Detection of cholangiocarcinoma with magnetic resonance spectroscopy of bile in patients with and without primary sclerosing cholangitisN Albiin
Division of Radiology, Department for Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden
Acta Radiol 49:855-62. 2008..Early detection of cholangiocarcinoma (CC) is very difficult, especially in patients with primary sclerosing cholangitis (PSC) who are at increased risk of developing CC... - Diagnostic and prognostic implications of DNA ploidy and S-phase evaluation in the assessment of malignancy in biliary stricturesB Lindberg
Department of Radiology, Karolinska University Hospital, Karolinska Institutet, Sweden
Endoscopy 38:561-5. 2006..The aim of the present study was to assess the diagnostic and prognostic importance of DNA measurements as an adjunct to brush cytology in patients with biliary strictures... 
Alcohol consumption in patients with primary sclerosing cholangitisHannes Hagström
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institutet, 14186 Stockholm, Sweden
World J Gastroenterol 18:3105-11. 2012..To assess the alcohol drinking patterns in a cohort of primary sclerosing cholangitis (PSC) patients and the possible influence on the development of fibrosis...- Perinatal events and the risk of developing primary sclerosing cholangitisAnnika Bergquist
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Sweden
World J Gastroenterol 12:6037-40. 2006..To investigate whether perinatal events, intrauterine or postpartum, are associated with the development of primary sclerosing cholangitis (PSC) later in life... - Increased risk of colorectal cancer and dysplasia in patients with Crohn's colitis and primary sclerosing cholangitisLina Lindström
Division of Gastroenterology and Hepatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Dis Colon Rectum 54:1392-7. 2011..Clinical characteristics and the risk of colon cancer or dysplasia in Crohn's disease and primary sclerosing cholangitis are less well examined than in ulcerative colitis... - Primary sclerosing cholangitis, inflammatory bowel disease, and colon cancerUlrika Broome
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
Semin Liver Dis 26:31-41. 2006..In patients having an ileal pelvic pouch with ileal anal anastomosis, PSC is a risk factor for development of pouchitis. It is important that all PSC patients with UC are included in colonoscopic surveillance programs... - Gallbladder emptying in patients with primary sclerosing cholangitisKarouk Said
Department of Gastroenterology and Hepatology, Karolinska Institute, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
World J Gastroenterol 15:3498-503. 2009..To assess gallbladder emptying and its association with cholecystitis and abdominal pain in patients with primary sclerosing cholangitis (PSC)... - Living-related liver transplantation in children--a single center evaluation of the outcome of donor candidates and recipientsBjorn Fischler
Department of Pediatrics, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
Pediatr Transplant 12:531-5. 2008..The fact that parents of BA patients have potential liver pathology may be of importance for the understanding of the etiology of the disease and have possible implications for the choice of donors... - High dose ursodeoxycholic acid in primary sclerosing cholangitis does not prevent colorectal neoplasiaL Lindstrom
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Huddinge, Stockholm, Sweden
Aliment Pharmacol Ther 35:451-7. 2012..Ursodeoxycholic acid (UDCA) has been suggested to have chemopreventive effects on the development of colorectal cancer and dysplasia but long-term data and larger trials are lacking... - Liver transplantation of patients with cryptogenic cirrhosis: clinical characteristics and outcomeJoel Marmur
Department of Gastroenterology and Hepatology, Karolinska Institutet, Ersta Hospital, Stockholm, Sweden
Scand J Gastroenterol 45:60-9. 2010.... - Clinical features in primary sclerosing cholangitisA Bergquist
Department of Gastroenterology and Hepatology, Huddinge University Hospital, Karolinska Institute, Huddinge, Sweden
Clin Liver Dis 2:283-301, viii. 1998..This article describes clinical features in primary sclerosing cholangitis, including clinical presentation and complications. The natural history of the disease is discussed, as well as the strong association to inflammatory bowel disease... - Time-dependent Cox regression model is superior in prediction of prognosis in primary sclerosing cholangitisKirsten Muri Boberg
Medical Department, Rikshospitalet, 0027 Oslo, Norway
Hepatology 35:652-7. 2002..In conclusion, a time-dependent Cox regression model has the potential to estimate a more precise short-term prognosis in PSC compared with the traditional time-fixed models... - [Acute liver failure--rapid multidisciplinary management]Einar Bjornsson
Medicinkliniken, Gastrosektionen, Sahlgrenska Universitetssjukhuset, Goteborg
Lakartidningen 104:210-3. 2007 - An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitisEspen Melum
Am J Gastroenterol 103:1045; author reply 1045-6. 2008 - The natural history of small-duct primary sclerosing cholangitisEinar Bjornsson
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden
Gastroenterology 134:975-80. 2008..We aimed at determining the natural history and long-term outcomes of a large number of patients with small-duct PSC... - Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitisTom H Karlsen
Medical Department, Rikshospitalet Radiumhospitalet Medical Center, University of Oslo, Oslo, Norway
J Hepatol 46:899-906. 2007..We aimed to clarify to what extent such combinations influence susceptibility to primary sclerosing cholangitis (PSC)... - Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphismsEspen Melum
Medical Department, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
Hepatology 47:90-6. 2008..Patients who are homozygous for the nonrisk alleles are unlikely to develop CCA; this finding could be helpful in identifying PSC patients with a low CCA risk...