L Holmberg

Summary

Country: Sweden

Publications

  1. ncbi request reprint Pre-operative oestradiol levels - relation to survival in breast cancer
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, MA, S 751 85, Sweden
    Eur J Surg Oncol 27:152-6. 2001
  2. ncbi request reprint Time trends in the results of breast conservation in 4694 women
    I Fredriksson
    The Karolinska Institute, Department of Surgery, Stockholm Soder Hospital, Stockholm, Sweden
    Eur J Cancer 37:1537-44. 2001
  3. ncbi request reprint Risk factors for local recurrence after breast-conserving surgery
    I Fredriksson
    Department of Surgery, The Karolinska Institute, Stockholm Soder Hospital, Stockholm, Sweden
    Br J Surg 90:1093-102. 2003
  4. doi request reprint Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trial
    Eva Johansson
    Department of Surgical Sciences, University Hospital of Uppsala, Uppsala, Sweden
    Lancet Oncol 12:891-9. 2011
  5. pmc Defining a high mortality risk group among women with primary breast cancer
    T Norden
    Department of Surgery, University Hospital, Uppsala, Sweden
    Br J Cancer 69:520-4. 1994
  6. ncbi request reprint Risk factors for subsequent invasive breast cancer and breast cancer death after ductal carcinoma in situ: a population-based case-control study in Sweden
    F Warnberg
    Department of Surgery, University Hospital, S 751 85 Uppsala, Sweden
    Cancer Epidemiol Biomarkers Prev 10:495-9. 2001
  7. ncbi request reprint 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial
    G Liljegren
    Department of Surgery, Orebro Medical Center Hospital, Orebro, Sweden
    J Clin Oncol 17:2326-33. 1999
  8. pmc Tumour markers in breast carcinoma correlate with grade rather than with invasiveness
    F Warnberg
    Department of Surgery, University Hospital Uppsala, S 751 85 Uppsala, Sweden
    Br J Cancer 85:869-74. 2001
  9. ncbi request reprint Preoperative serum levels of follicle stimulating hormone (FSH) and prognosis in invasive breast cancer
    M Eskelinen
    Regional Oncologic Center and Department of Surgery, University of Uppsala, Uppsala, Sweden
    Eur J Surg Oncol 30:495-500. 2004
  10. pmc Population based case-control study of sick leave in postmenopausal women before diagnosis of hyperparathyroidism
    E Lundgren
    Department of Surgery, Uppsala University, S 751 85 Uppsala, Sweden
    BMJ 317:848-51. 1998

Detail Information

Publications28

  1. ncbi request reprint Pre-operative oestradiol levels - relation to survival in breast cancer
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, MA, S 751 85, Sweden
    Eur J Surg Oncol 27:152-6. 2001
    ..However, few studies have information on plasma levels of hormones pre-operatively...
  2. ncbi request reprint Time trends in the results of breast conservation in 4694 women
    I Fredriksson
    The Karolinska Institute, Department of Surgery, Stockholm Soder Hospital, Stockholm, Sweden
    Eur J Cancer 37:1537-44. 2001
    ..5 (95% confidence interval (CI) 1.0--2.1). Corrected survival was 93.3 and 85.2% at 5 and 10 years, respectively...
  3. ncbi request reprint Risk factors for local recurrence after breast-conserving surgery
    I Fredriksson
    Department of Surgery, The Karolinska Institute, Stockholm Soder Hospital, Stockholm, Sweden
    Br J Surg 90:1093-102. 2003
    ..Furthermore, the Nottingham Prognostic Index (NPI) and Nottingham Histological Grade (NHG) have been little studied as determinants of local recurrence risk...
  4. doi request reprint Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trial
    Eva Johansson
    Department of Surgical Sciences, University Hospital of Uppsala, Uppsala, Sweden
    Lancet Oncol 12:891-9. 2011
    ..We report results for quality of life for men in the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) after a median follow-up of more than 12 years...
  5. pmc Defining a high mortality risk group among women with primary breast cancer
    T Norden
    Department of Surgery, University Hospital, Uppsala, Sweden
    Br J Cancer 69:520-4. 1994
    ..Women with no involved nodes and with three or four negative factors had a risk of dying from breast cancer similar to that of node-positive women with fewer than three...
  6. ncbi request reprint Risk factors for subsequent invasive breast cancer and breast cancer death after ductal carcinoma in situ: a population-based case-control study in Sweden
    F Warnberg
    Department of Surgery, University Hospital, S 751 85 Uppsala, Sweden
    Cancer Epidemiol Biomarkers Prev 10:495-9. 2001
    ..The driving forces behind local and generalized disease may differ. Because confounding by indication may influence the effects of different treatments, the results should be interpreted with caution...
  7. ncbi request reprint 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial
    G Liljegren
    Department of Surgery, Orebro Medical Center Hospital, Orebro, Sweden
    J Clin Oncol 17:2326-33. 1999
    ..To study the long-term effectiveness of postoperative radiotherapy after sector resection for breast cancer in a randomized trial in which mammography is a major pathway to diagnosis...
  8. pmc Tumour markers in breast carcinoma correlate with grade rather than with invasiveness
    F Warnberg
    Department of Surgery, University Hospital Uppsala, S 751 85 Uppsala, Sweden
    Br J Cancer 85:869-74. 2001
    ..The results suggest that well-differentiated DCIS progress to well-differentiated invasive cancer and poorly differentiated DCIS progress to poorly differentiated invasive cancer...
  9. ncbi request reprint Preoperative serum levels of follicle stimulating hormone (FSH) and prognosis in invasive breast cancer
    M Eskelinen
    Regional Oncologic Center and Department of Surgery, University of Uppsala, Uppsala, Sweden
    Eur J Surg Oncol 30:495-500. 2004
    ..We investigated the association between preoperative serum levels of follicle stimulating hormone (FSH) and the prognosis in women with invasive breast cancer...
  10. pmc Population based case-control study of sick leave in postmenopausal women before diagnosis of hyperparathyroidism
    E Lundgren
    Department of Surgery, Uppsala University, S 751 85 Uppsala, Sweden
    BMJ 317:848-51. 1998
    ..To analyse sick leave in women at risk of primary hyperparathyroidism before its diagnosis...
  11. ncbi request reprint Age as a determinant of axillary node involvement in invasive breast cancer
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, Sweden
    Acta Oncol 31:533-8. 1992
    ..The findings indicate that the parallelism between the establishment of metastases in lymph nodes and at distant sites may vary with age. The prognostic value of nodal status may therefore depend on age at diagnosis...
  12. ncbi request reprint Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture
    H Melhus
    University Hospital, Uppsala, Sweden
    Ann Intern Med 129:770-8. 1998
    ..The highest incidence of osteoporotic fractures is found in northern Europe, where dietary intake of vitamin A (retinol) is unusually high. In animals, the most common adverse effect of toxic doses of retinol is spontaneous fracture...
  13. ncbi request reprint Intensified primary cancer care: a randomized study of home care nurse contacts
    B Johansson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    J Adv Nurs 30:1137-46. 1999
    ....
  14. pmc Prognosis in bilateral breast cancer. Effects of time interval between first and second primary tumours
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, Sweden
    Br J Cancer 58:191-4. 1988
    ..The results indicate that the two tumours contribute independently to the patient's excess risk of dying and thus occur as two seemingly biologically unrelated events with respect to the tumour-host relationship and metastatic behaviour...
  15. doi request reprint Time, symptom burden, androgen deprivation, and self-assessed quality of life after radical prostatectomy or watchful waiting: the Randomized Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) clinical trial
    Eva Johansson
    Department of Urology, Uppsala University Hospital, Uppsala, Sweden
    Eur Urol 55:422-30. 2009
    ..Quality-of-life outcomes are important in the choice of treatment strategy for men with localized prostate cancer...
  16. ncbi request reprint Nurse-led follow-up on demand or by a physician after breast cancer surgery: a randomised study
    I L Koinberg
    Department of Surgery, Varberg Hosptial, Sweden
    Eur J Oncol Nurs 8:109-17; discussion 118-20. 2004
    ..This study indicates that women with breast cancer in stages I to II can be followed up by a specialist nurse with high patient satisfaction and good medical safety...
  17. pmc Failure to detect early breast cancer using in vitro nuclear magnetic resonance spectroscopy of plasma
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, Sweden
    Br J Cancer 68:389-92. 1993
    ..7 Hz). In vitro NMR spectroscopy in our hands was thus not a useful diagnostic tool in patients with early breast cancer...
  18. ncbi request reprint Breast-conserving surgery without radiotherapy
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, Sweden
    Acta Oncol 34:681-3. 1995
    ..4) If the long-term--positive and negative--effects of radiotherapy were better quantified. Until we have new information, postoperative radiotherapy after breast conservation remains the standard...
  19. pmc Radiation to supraclavicular and internal mammary lymph nodes in breast cancer increases the risk of stroke
    G Nilsson
    Department of Oncology, Radiology and Clinical Immunology, University Hospital, Uppsala, Sweden
    Br J Cancer 100:811-6. 2009
    ..Our finding of a target-specific increased risk of stroke and a dose-response relationship for daily fraction dose, indicate that there may be a causal link between RT to the IMC and SCL and risk of stroke...
  20. ncbi request reprint Local recurrence in the breast after conservative surgery--a study of prognosis and prognostic factors in 391 women
    I Fredriksson
    The Karolinska Institute, Department of Surgery, Stockholm Soder Hospital, SE 11883 Stockholm, Sweden
    Eur J Cancer 38:1860-70. 2002
    ..Independent prognostic factors for breast cancer-specific survival in women with local recurrences were time to local recurrence and the Nottingham Prognostic Index (NPI)...
  21. doi request reprint Anti-androgen prescribing patterns, patient treatment adherence and influencing factors; results from the nationwide PCBaSe Sweden
    B Grundmark
    Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
    Eur J Clin Pharmacol 68:1619-30. 2012
    ....
  22. ncbi request reprint HABITS (hormonal replacement therapy after breast cancer--is it safe?), a randomised comparison: trial stopped
    L Holmberg
    Regional Oncologic Centre, University Hospital, SE 751 85 Uppsala, Sweden
    Lancet 363:453-5. 2004
    ..We decided that these findings indicated an unacceptable risk for women exposed to HRT in the HABITS trial, and the trial was terminated on Dec 17, 2003...
  23. ncbi request reprint Literature review of surgical management of abdominal aortic aneurysm
    A Hallin
    Department of Surgery, Falu Hospital, Falun, SE-791 82, Sweden
    Eur J Vasc Endovasc Surg 22:197-204. 2001
    ..The overview revealed several methodological problems in the reported studies. CONCLUSIONS: The results can be used as the basis of quality assurance or in decision trees or other models. Better reporting standards are needed...
  24. ncbi request reprint Sector resection with and without radiotherapy in early breast cancer. Presentation of two ongoing prospective multicenter studies in Sweden. Uppsala/Orebro Breast Cancer Study Group
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, Sweden
    Acta Oncol 28:927-9. 1989
    ..Overall 5% of the women in the conservatively treated group and 22% of the mastectomized women are still suffering substantial psychosocial disturbance after 13 months...
  25. ncbi request reprint Trends in childhood and adolescent cancer survival in Sweden 1960 through 1984
    H O Adami
    Cancer Epidemiology Unit, University Hospital, Uppsala, Sweden
    Acta Oncol 31:1-10. 1992
    ..Our data reflect the remarkable therapeutic improvements that have occurred for cancer in the young and indicate that these improvements have rapidly become available in Sweden...
  26. ncbi request reprint Ductal carcinoma in situ of the breast: a new phenotype classification system and its relation to prognosis
    F Warnberg
    Department of Surgery, University Hospital, Uppsala, Sweden
    Breast Cancer Res Treat 73:215-21. 2002
    ....
  27. ncbi request reprint Adverse effects after radical external beam radiotherapy of localized prostatic adenocarcinoma using two-dimensional dose-planning and a limited field technique
    G Ljung
    Department of Oncology, Akademiska sjukhuset, University Hospital, Uppsala, Sweden
    Acta Oncol 35:445-50. 1996
    ..Sexual functions were substantially affected in 60% of cases not administered endocrine treatment. Multivariate analyses could not identify patient or treatment risk factors related to complications...
  28. ncbi request reprint Role of surgery in invasive breast cancer
    L Holmberg
    Department of Surgery, University Hospital, Uppsala, Sweden
    Acta Oncol 34:625-8. 1995
    ....