Research Topics
| L HolmbergSummaryCountry: Sweden Publications
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Detail Information
Publications
Pre-operative oestradiol levels - relation to survival in breast cancerL Holmberg
Department of Surgery, University Hospital, Uppsala, MA, S 751 85, Sweden
Eur J Surg Oncol 27:152-6. 2001..However, few studies have information on plasma levels of hormones pre-operatively...
Time trends in the results of breast conservation in 4694 womenI Fredriksson
The Karolinska Institute, Department of Surgery, Stockholm Soder Hospital, Stockholm, Sweden
Eur J Cancer 37:1537-44. 2001..5 (95% confidence interval (CI) 1.0--2.1). Corrected survival was 93.3 and 85.2% at 5 and 10 years, respectively...
Risk factors for local recurrence after breast-conserving surgeryI Fredriksson
Department of Surgery, The Karolinska Institute, , Stockholm, Sweden
Br J Surg 90:1093-102. 2003..With the exception of surgical margin, variables related to the quality of surgical management did not predict risk of local recurrence...
Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trialEva Johansson
Department of Surgical Sciences, University Hospital of Uppsala, Uppsala, Sweden
Lancet Oncol 12:891-9. 2011..We report results for quality of life for men in the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) after a median follow-up of more than 12 years...
Defining a high mortality risk group among women with primary breast cancerT Norden
Department of Surgery, University Hospital, Uppsala, Sweden
Br J Cancer 69:520-4. 1994..Women with no involved nodes and with three or four negative factors had a risk of dying from breast cancer similar to that of node-positive women with fewer than three...
10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trialG Liljegren
Department of Surgery, Orebro Medical Center Hospital, Orebro, Sweden
J Clin Oncol 17:2326-33. 1999..To study the long-term effectiveness of postoperative radiotherapy after sector resection for breast cancer in a randomized trial in which mammography is a major pathway to diagnosis...
Risk factors for subsequent invasive breast cancer and breast cancer death after ductal carcinoma in situ: a population-based case-control study in SwedenF Warnberg
Department of Surgery, University Hospital, S 751 85 Uppsala, Sweden
Cancer Epidemiol Biomarkers Prev 10:495-9. 2001..The driving forces behind local and generalized disease may differ. Because confounding by indication may influence the effects of different treatments, the results should be interpreted with caution...
Tumour markers in breast carcinoma correlate with grade rather than with invasivenessF Warnberg
Department of Surgery, University Hospital Uppsala, S 751 85 Uppsala, Sweden
Br J Cancer 85:869-74. 2001..The results suggest that well-differentiated DCIS progress to well-differentiated invasive cancer and poorly differentiated DCIS progress to poorly differentiated invasive cancer...
Population based case-control study of sick leave in postmenopausal women before diagnosis of hyperparathyroidismE Lundgren
Department of Surgery, Uppsala University, S 751 85 Uppsala, Sweden
BMJ 317:848-51. 1998..To analyse sick leave in women at risk of primary hyperparathyroidism before its diagnosis...
Preoperative serum levels of follicle stimulating hormone (FSH) and prognosis in invasive breast cancerM Eskelinen
Regional Oncologic Center and Department of Surgery, University of Uppsala, Uppsala, Sweden
Eur J Surg Oncol 30:495-500. 2004..Today, FSH is not a clinical target for intervention or a clinically useful prognostic factor and the results of clinical studies up to date can only be used for motivation of further experimental laboratory research...
Age as a determinant of axillary node involvement in invasive breast cancerL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 31:533-8. 1992..The findings indicate that the parallelism between the establishment of metastases in lymph nodes and at distant sites may vary with age. The prognostic value of nodal status may therefore depend on age at diagnosis...
Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fractureH Melhus
University Hospital, Uppsala, Sweden
Ann Intern Med 129:770-8. 1998..The highest incidence of osteoporotic fractures is found in northern Europe, where dietary intake of vitamin A (retinol) is unusually high. In animals, the most common adverse effect of toxic doses of retinol is spontaneous fracture...
Intensified primary cancer care: a randomized study of home care nurse contactsB Johansson
Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
J Adv Nurs 30:1137-46. 1999....
Prognosis in bilateral breast cancer. Effects of time interval between first and second primary tumoursL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Br J Cancer 58:191-4. 1988..The results indicate that the two tumours contribute independently to the patient's excess risk of dying and thus occur as two seemingly biologically unrelated events with respect to the tumour-host relationship and metastatic behaviour...
Local recurrence in the breast after conservative surgery--a study of prognosis and prognostic factors in 391 womenI Fredriksson
The Karolinska Institute, Department of Surgery, Stockholm Soder Hospital, SE 11883 Stockholm, Sweden
Eur J Cancer 38:1860-70. 2002..Independent prognostic factors for breast cancer-specific survival in women with local recurrences were time to local recurrence and the Nottingham Prognostic Index (NPI)...
Nurse-led follow-up on demand or by a physician after breast cancer surgery: a randomised studyI L Koinberg
Department of Surgery, Varberg Hosptial, Sweden
Eur J Oncol Nurs 8:109-17; discussion 118-20. 2004..This study indicates that women with breast cancer in stages I to II can be followed up by a specialist nurse with high patient satisfaction and good medical safety...
Radiation to supraclavicular and internal mammary lymph nodes in breast cancer increases the risk of strokeG Nilsson
Department of Oncology, Radiology and Clinical Immunology, University Hospital, Uppsala, Sweden
Br J Cancer 100:811-6. 2009..Our finding of a target-specific increased risk of stroke and a dose-response relationship for daily fraction dose, indicate that there may be a causal link between RT to the IMC and SCL and risk of stroke...
Breast-conserving surgery without radiotherapyL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 34:681-3. 1995..4) If the long-term--positive and negative--effects of radiotherapy were better quantified. Until we have new information, postoperative radiotherapy after breast conservation remains the standard...
Time, symptom burden, androgen deprivation, and self-assessed quality of life after radical prostatectomy or watchful waiting: the Randomized Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) clinical trialEva Johansson
Department of Urology, Uppsala University Hospital, Uppsala, Sweden
Eur Urol 55:422-30. 2009..Quality-of-life outcomes are important in the choice of treatment strategy for men with localized prostate cancer...
Failure to detect early breast cancer using in vitro nuclear magnetic resonance spectroscopy of plasmaL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Br J Cancer 68:389-92. 1993..7 Hz). In vitro NMR spectroscopy in our hands was thus not a useful diagnostic tool in patients with early breast cancer...
HABITS (hormonal replacement therapy after breast cancer--is it safe?), a randomised comparison: trial stoppedL Holmberg
Regional Oncologic Centre, University Hospital, SE 751 85 Uppsala, Sweden
Lancet 363:453-5. 2004..We decided that these findings indicated an unacceptable risk for women exposed to HRT in the HABITS trial, and the trial was terminated on Dec 17, 2003...
Literature review of surgical management of abdominal aortic aneurysmA Hallin
Department of Surgery, Falu Hospital, Falun, SE-791 82, Sweden
Eur J Vasc Endovasc Surg 22:197-204. 2001..The overview revealed several methodological problems in the reported studies. CONCLUSIONS: The results can be used as the basis of quality assurance or in decision trees or other models. Better reporting standards are needed...
Trends in childhood and adolescent cancer survival in Sweden 1960 through 1984H O Adami
Cancer Epidemiology Unit, University Hospital, Uppsala, Sweden
Acta Oncol 31:1-10. 1992..Our data reflect the remarkable therapeutic improvements that have occurred for cancer in the young and indicate that these improvements have rapidly become available in Sweden...
Sector resection with and without radiotherapy in early breast cancer. Presentation of two ongoing prospective multicenter studies in Sweden. Uppsala/Orebro Breast Cancer Study GroupL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 28:927-9. 1989..Overall 5% of the women in the conservatively treated group and 22% of the mastectomized women are still suffering substantial psychosocial disturbance after 13 months...
Anti-androgen prescribing patterns, patient treatment adherence and influencing factors; results from the nationwide PCBaSe SwedenB Grundmark
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Eur J Clin Pharmacol 68:1619-30. 2012....
Ductal carcinoma in situ of the breast: a new phenotype classification system and its relation to prognosisF Warnberg
Department of Surgery, University Hospital, Uppsala, Sweden
Breast Cancer Res Treat 73:215-21. 2002....
Adverse effects after radical external beam radiotherapy of localized prostatic adenocarcinoma using two-dimensional dose-planning and a limited field techniqueG Ljung
Department of Oncology, Akademiska sjukhuset, University Hospital, Uppsala, Sweden
Acta Oncol 35:445-50. 1996..Sexual functions were substantially affected in 60% of cases not administered endocrine treatment. Multivariate analyses could not identify patient or treatment risk factors related to complications...
Role of surgery in invasive breast cancerL Holmberg
Department of Surgery, University Hospital, Uppsala, Sweden
Acta Oncol 34:625-8. 1995....
