C Hesse

Summary

Country: Sweden

Publications

  1. ncbi A quantitative and immunohistochemical study on apolipoprotein E in brain tissue in Alzheimer's disease
    C Hesse
    Department of Clinical Neuroscience, Unit of Neurochemistry, University of Goteborg, Sahlgren s University Hospital, Molndal, Sweden
    Dement Geriatr Cogn Disord 10:452-9. 1999
  2. ncbi Measurement of apolipoprotein E (apoE) in cerebrospinal fluid
    C Hesse
    Institute of Clinical Neuroscience, Unit of Neurochemistry, University of Goteborg, Sahlgren s University Hospital Mölndal, Sweden
    Neurochem Res 25:511-7. 2000
  3. ncbi No association between the alpha2-macroglobulin (A2M) deletion and Alzheimer's disease, and no change in A2M mRNA, protein, or protein expression
    K Blennow
    Department of Clinical Neuroscience, University of Goteborg, Sahlgren s University Hospital, Molndal, Sweden
    J Neural Transm 107:1065-79. 2000
  4. ncbi Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease
    P Davidsson
    Department of Clinical Neuroscience, Experimental Neuroscience Section, Goteborg University, Sahlgrenska University Hospital, S 431 80, Molndal, Sweden
    Neurosci Lett 300:157-60. 2001
  5. ncbi Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke
    C Hesse
    Institute of Clinical Neuroscience, Unit of Neurochemistry, , , SE-431 80, , Sweden
    Neurosci Lett 297:187-90. 2001
  6. ncbi Identification of the apolipoprotein E4 isoform in cerebrospinal fluid with preparative two-dimensional electrophoresis and matrix assisted laser desorption/ionization-time of flight-mass spectrometry
    C Hesse
    Department of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital Molndal, Sweden
    Electrophoresis 22:1834-7. 2001
  7. ncbi Tacrine and rate of progression in Alzheimer's disease--relation to ApoE allele genotype
    M Sjogren
    Institute of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital Molndal, Sweden
    J Neural Transm 108:451-8. 2001
  8. ncbi Proteome studies of human cerebrospinal fluid and brain tissue using a preparative two-dimensional electrophoresis approach prior to mass spectrometry
    P Davidsson
    Department of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital Molndal, Sweden
    Proteomics 1:444-52. 2001

Detail Information

Publications8

  1. ncbi A quantitative and immunohistochemical study on apolipoprotein E in brain tissue in Alzheimer's disease
    C Hesse
    Department of Clinical Neuroscience, Unit of Neurochemistry, University of Goteborg, Sahlgren s University Hospital, Molndal, Sweden
    Dement Geriatr Cogn Disord 10:452-9. 1999
    ..One may speculate whether the decrease in ApoE may suggest a disturbance in the ApoE system in AD that is unrelated to ApoE isoforms, beta-amyloid deposition and NFT formation. Copyrightz1999S.KargerAG,Basel..
  2. ncbi Measurement of apolipoprotein E (apoE) in cerebrospinal fluid
    C Hesse
    Institute of Clinical Neuroscience, Unit of Neurochemistry, University of Goteborg, Sahlgren s University Hospital Mölndal, Sweden
    Neurochem Res 25:511-7. 2000
    ..Differences in the amount of patients and controls possessing the ApoE4 allele included might also increase the variance between different studies...
  3. ncbi No association between the alpha2-macroglobulin (A2M) deletion and Alzheimer's disease, and no change in A2M mRNA, protein, or protein expression
    K Blennow
    Department of Clinical Neuroscience, University of Goteborg, Sahlgren s University Hospital, Molndal, Sweden
    J Neural Transm 107:1065-79. 2000
    ..The lack of an association between the A2M-2 allele and AD in the present study, and the lack of abnormalities in the A2M mRNA or protein suggest that the A2M-2 allele is not associated with AD...
  4. ncbi Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease
    P Davidsson
    Department of Clinical Neuroscience, Experimental Neuroscience Section, Goteborg University, Sahlgrenska University Hospital, S 431 80, Molndal, Sweden
    Neurosci Lett 300:157-60. 2001
    ..These data suggest that CSF biomarkers are capable not only of identifying a biochemical effect of drugs, but also of differentiating between different compounds in a dose-dependent manner...
  5. ncbi Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke
    C Hesse
    Institute of Clinical Neuroscience, Unit of Neurochemistry, , , SE-431 80, , Sweden
    Neurosci Lett 297:187-90. 2001
    ....
  6. ncbi Identification of the apolipoprotein E4 isoform in cerebrospinal fluid with preparative two-dimensional electrophoresis and matrix assisted laser desorption/ionization-time of flight-mass spectrometry
    C Hesse
    Department of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital Molndal, Sweden
    Electrophoresis 22:1834-7. 2001
    ..Characterization of proteins and their modifications (amino acid substitutions, glycosylation or phosphorylation) in CSF will be a useful tool in the investigation of the pathophysiology of brain disorders such as AD...
  7. ncbi Tacrine and rate of progression in Alzheimer's disease--relation to ApoE allele genotype
    M Sjogren
    Institute of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital Molndal, Sweden
    J Neural Transm 108:451-8. 2001
    ..The results primarily suggest a faster rate of decline in the ApoE4 AD compared to the ApoE2-3, but may also reflect that ApoE epsilon4 genotype inheritance is a negative predictor of treatment effect of tacrine in AD patients...
  8. ncbi Proteome studies of human cerebrospinal fluid and brain tissue using a preparative two-dimensional electrophoresis approach prior to mass spectrometry
    P Davidsson
    Department of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital Molndal, Sweden
    Proteomics 1:444-52. 2001
    ..The use of this strategy in proteome studies of CSF/brain tissue is expected to offer new perspectives in studies of the pathology of neurodegenerative diseases, and reveal new potential markers for brain disorders...