Affiliation: Helsingborg Hospital
- Defective mismatch-repair as a minor tumorigenic pathway in Barrett esophagus-associated adenocarcinomaDan Falkenback
Department of Surgery, University Hospital, S 221 85 Lund, Sweden
Cancer Genet Cytogenet 157:82-6. 2005..Our findings suggest that only a small subset of Barrett adenocarcinomas develop because of defective MMR, but demonstrate that MLH1 and MSH2 are the primary targets for defective MMR also in this tumor type...
- Heller's esophagomyotomy with or without a 360 degrees floppy Nissen fundoplication for achalasia. Long-term results from a prospective randomized studyD Falkenback
Department of Surgery, Business Area Elective Surgery, Helsingborg Hospital Inc, Helsingborg, Sweden
Dis Esophagus 16:284-90. 2003..The addition of a 360 degrees fundoplication eliminates reflux without adding dysphagia in the majority of patients and can be recommended for most patients with uncomplicated achalasia...
- Prognostic value of cell adhesion in esophageal adenocarcinomasD Falkenback
Department of Surgery, Institute of Clinical Sciences, Lund University Hospital, Lund, Sweden
Dis Esophagus 21:97-102. 2008..The down-regulation of E-cadherin and its prognostic importance indicate that cell adhesion may be a prime area for targeted therapies in esophageal adenocarcinoma...
- Prognostic impact of array-based genomic profiles in esophageal squamous cell cancerAna Carneiro
Department of Oncology, Lund University Hospital, 221 85 Lund, Sweden
BMC Cancer 8:98. 2008..We applied array-based comparative genomic hybridization (aCGH) to obtain a whole genome copy number profile relevant for identifying deranged pathways and clinically applicable markers...