Research Topics
| A HeijlSummaryCountry: Sweden Publications
Research Grants
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Detail Information
Publications
An evidence-based glaucoma guidelineAnders Heijl
Acta Ophthalmol Scand 81:2. 2003
Acta ophthalmologica and the netAnders Heijl
Acta Ophthalmol Scand 81:210. 2003
Risk of glaucoma in ocular hypertension with and without pseudoexfoliationKirsti Grødum
Department of Ophthalmology, Malmo University Hospital, University of Lund, Malmo, Sweden
Ophthalmology 112:386-90. 2005..To compare glaucoma conversion rates in patients with ocular hypertension (OH) with and without pseudoexfoliation...
Visual acuity and perimetry as measures of visual function in diabetic macular oedemaE Agardh
Department of Ophthalmology, Malmo University Hospital, SE 205 02, Malmo, Sweden
Diabetologia 49:200-6. 2006..We examined to what extent visual acuity and perimetric sensitivity as measures of central and paracentral visual function would be useful for evaluating the presence and severity of diabetic macular oedema...
Glaucoma follow-up when converting from long to short perimetric threshold testsA Heijl
Department of Ophthalmology, Malmo, Sweden
Arch Ophthalmol 118:489-93. 2000....
Nordic research in ophthalmologyAnders Heijl
Department of Ophthalmology, Malmo University Hospital, Malmo, Sweden
Acta Ophthalmol Scand 83:278-88. 2005..This paper does not represent a comprehensive review of all Nordic research in the field, but attempts to give an overview of some of the activities underway in eye research in this part of the world...
Measuring visual field progression in the Early Manifest Glaucoma TrialAnders Heijl
Department of Ophthalmology, Malmo University Hospital, Malmo, Sweden
Acta Ophthalmol Scand 81:286-93. 2003..This paper provides estimates of the amount of visual field worsening required to reach the EMGT definition of definite perimetric progression...
Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma TrialAnders Heijl
Department of Ophthalmology, Malmo University Hospital, SE 20502 Malmo, Sweden
Arch Ophthalmol 120:1268-79. 2002..To provide the results of the Early Manifest Glaucoma Trial, which compared the effect of immediately lowering the intraocular pressure (IOP), vs no treatment or later treatment, on the progression of newly detected open-angle glaucoma...
Long-term effects of timolol therapy in ocular hypertension: a double-masked, randomised trialA Heijl
Department of Ophthalmology, Malmo University Hospital, 20502 Malmo, Sweden
Graefes Arch Clin Exp Ophthalmol 238:877-83. 2000..The aim of the current paper was to report the results of a long-term study addressing this very problem...
Fluctuation of intraocular pressure and glaucoma progression in the early manifest glaucoma trialBoel Bengtsson
Department of Clinical Sciences, Ophthalmology, Lund University, Malmo University Hospital, Malmo, Sweden
Ophthalmology 114:205-9. 2007..To investigate whether increased fluctuation of intraocular pressure (IOP) is an independent factor for glaucoma progression...
Optic nerve head sector analysis recognizes glaucoma most effectively around disc polesK G Gundersen
Department of Ophthalmology, Malmo University Hospital, Sweden
Acta Ophthalmol Scand 77:13-8. 1999..To analyze the topography of normal and glaucomatous discs with the goal of developing improved strategies to discriminate between normal and glaucomatous eyes...
Age, gender, IOP, refraction and optic disc topography in normal eyes. A cross-sectional study using raster and scanning laser tomographyK G Gundersen
Department of Ophthalmology, Malmo University Hospital, Sweden
Acta Ophthalmol Scand 76:170-5. 1998..To study the influence of age, gender, intraocular pressure and refraction on optic disc topography in normal subjects...
Disc hemorrhages and treatment in the early manifest glaucoma trialBoel Bengtsson
Department of Clinical Sciences, Ophthalmology, Lund University, Malmo University Hospital, Sweden
Ophthalmology 115:2044-8. 2008..To evaluate the effect of intraocular pressure (IOP)-reducing treatment on the development of disc hemorrhages in patients with glaucoma...
Natural history of open-angle glaucomaAnders Heijl
Department of Ophthalmology, Lund University, Malmo University Hospital, Malmo, Sweden
Ophthalmology 116:2271-6. 2009..This article, based on the Early Manifest Glaucoma Trial (EMGT), provides prospective natural history data on progression of glaucomatous field defects in 3 of the most common glaucoma types...
Lack of long-term drift in timolol's effectiveness in patients with ocular hypertensionB Bengtsson
Department of Ophthalmology, Malmo University Hospital, Sweden
Invest Ophthalmol Vis Sci 42:2839-42. 2001..To report the change over time in intraocular pressure in patients treated with topical timolol or placebo...
Timolol increased retrobulbar flow velocities in untreated glaucoma eyes but not in ocular hypertensionI C Bergstrand
Department of Ophthalmology, Malmo University Hospital, Malmo, Sweden
Acta Ophthalmol Scand 79:455-61. 2001..To investigate retrobulbar blood flow velocities and the effects of topical timolol treatment in eyes with newly detected, previously untreated open angle glaucoma or ocular hypertension...
Diagnostic sensitivity of fast blue-yellow and standard automated perimetry in early glaucoma: a comparison between different test programsBoel Bengtsson
Department of Clinical Sciences, Ophthalmology, , Lund University, SE 205 02 Malm, Sweden
Ophthalmology 113:1092-7. 2006..Conventional SAP using SITA Fast was not significantly less sensitive than either of the 2 SWAP programs...
A comparison of visual field progression criteria of 3 major glaucoma trials in early manifest glaucoma trial patientsAnders Heijl
Department of Ophthalmology, Lund University, Malmo University Hospital, Malmo, Sweden
Ophthalmology 115:1557-65. 2008..This article compares the performance of these criteria with a reference standard of unanimous classifications by 3 independent glaucoma experts...
Comparing significance and magnitude of glaucomatous visual field defects using the SITA and Full Threshold strategiesB Bengtsson
Department of Ophthalmology, Malmo University Hospital, Sweden
Acta Ophthalmol Scand 77:143-6. 1999....
Focusing on glaucoma progression and the clinical importance of progression rate measurement: a reviewL Rossetti
Department of Ophthalmology, University Hospital, Lund University, Malmo, Sweden
Eye (Lond) 24:S1-7. 2010..Recent findings strongly indicate that continued monitoring of visual fields (VFs) and reassessment of target intraocular pressures (IOPs) depending on VF progression rates are mandatory in the management of glaucoma...
Optic disc classification by the Heidelberg Retina Tomograph and by physicians with varying experience of glaucomaS Andersson
Department of Clinical Sciences, Ophthalmology, Lund University, Skane University Hospital, Malmo, Sweden
Eye (Lond) 25:1401-7. 2011....
Trained artificial neural network for glaucoma diagnosis using visual field data: a comparison with conventional algorithmsDimitrios Bizios
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, SE 205 02 Malmo, Sweden
J Glaucoma 16:20-8. 2007....
A visual field index for calculation of glaucoma rate of progressionBoel Bengtsson
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, Malmo, Sweden
Am J Ophthalmol 145:343-53. 2008..To present a new perimetric index for calculating the rate of glaucomatous progression and to compare its performance with the traditional mean deviation index (MDI)...
Glaucomatous retinal nerve fibre layer defects may be identified in Stratus OCT images classified as normalJesper Leth Hougaard
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, Malmo, Sweden
Acta Ophthalmol 86:569-75. 2008..We aimed to compare the retinal nerve fibre layer (RNFL) in different Stratus optical coherence tomography (OCT) images in glaucoma eyes with RNFL thickness values within normal limits...
Prediction of glaucomatous visual field loss by extrapolation of linear trendsBoel Bengtsson
Departments of Clinical Sciences and Ophthalmology, Lund University, Malmo University Hospital, SE 20502 Malmo, Sweden
Arch Ophthalmol 127:1610-5. 2009..To investigate how well short-term progression rates can predict long-term visual field outcomes in patients with glaucoma...
Glaucoma detection using different Stratus optical coherence tomography protocolsJesper Leth Hougaard
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, Malmo, Sweden
Acta Ophthalmol Scand 85:251-6. 2007..To examine and compare the diagnostic accuracy of retinal nerve fibre layer (RNFL) thickness measurements using different Stratus optical coherence tomography (OCT) scanning protocols...
False-negative responses in glaucoma perimetry: indicators of patient performance or test reliability?B Bengtsson
Department of Ophthalmology, Malmo University Hospital, Sweden
Invest Ophthalmol Vis Sci 41:2201-4. 2000..To study whether false-negative answers in computerized glaucoma perimetry indicate the patient's ability to perform perimetry or test result reliability...
Inter-subject variability and normal limits of the SITA Standard, SITA Fast, and the Humphrey Full Threshold computerized perimetry strategies, SITA STATPACB Bengtsson
Department of Ophthalmology, Malmo University Hospital, Sweden
Acta Ophthalmol Scand 77:125-9. 1999..To establish and evaluate inter-subject variability and normal threshold limits for the new SITA strategies and to compare them with those obtained with the traditional Humphrey Full Threshold algorithm...
Comparability of three-dimensional optic disc imaging with different techniques. A study with confocal scanning laser tomography and raster tomographyK G Gundersen
Department of Ophthalmology, Malmo University Hospital, Sweden
Acta Ophthalmol Scand 78:9-13. 2000....
Glaucoma detection by Stratus OCTJesper Leth Hougaard
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, Sweden
J Glaucoma 16:302-6. 2007..To investigate the diagnostic accuracy of retinal nerve fiber layer thickness (RNFLT) summary report parameters from Stratus optical coherence tomography (OCT) in glaucoma patients...
A long-term prospective study of risk factors for glaucomatous visual field loss in patients with ocular hypertensionBoel Bengtsson
Department of Ophthalmology, Malmo University Hospital, Lund University, SE 205 02 Malmo, Sweden
J Glaucoma 14:135-8. 2005..To evaluate the importance of baseline risk factors for development of glaucomatous visual field loss in patients with high-risk ocular hypertension...
A comparison of glaucoma patients identified through mass screening and in routine clinical practiceKirsti Grødum
Department of Opthalmology, Malmo University, Malmo, Sweden
Acta Ophthalmol Scand 80:627-31. 2002..To study differences between glaucoma patients identified through a population screening and glaucoma patients diagnosed in routine clinical practice (self-selected patients)...
Normal intersubject threshold variability and normal limits of the SITA SWAP and full threshold SWAP perimetric programsBoel Bengtsson
Department of Ophthalmology, Malmo University Hospital, Lund University, Lund, Sweden
Invest Ophthalmol Vis Sci 44:5029-34. 2003....
Dorzolamide and ocular blood flow in previously untreated glaucoma patients: a controlled double-masked studyIngar C Bergstrand
Department of Ophthalmology, Malmo University Hospital, Malmo, Sweden
Acta Ophthalmol Scand 80:176-82. 2002..The aim of this study was to investigate the haemodynamic effects of topical dorzolamide treatment in eyes with newly detected and previously untreated glaucoma...
Effects of input data on the performance of a neural network in distinguishing normal and glaucomatous visual fieldsBoel Bengtsson
Department of Ophthalmology, Malmo University Hospital, Lund University, Sweden
Invest Ophthalmol Vis Sci 46:3730-6. 2005..Dublin, CA)...
Appearance of the pattern deviation map as a function of change in area of localized field lossPeter Asman
Department of Ophthalmology, Malmo University Hospital, Malmo, Sweden
Invest Ophthalmol Vis Sci 45:3099-106. 2004....
Glaucoma and mortalityKirsti Grødum
Department of Ophthalmology, Malmo University Hospital, S 20502, Sweden
Graefes Arch Clin Exp Ophthalmol 242:397-401. 2004..To compare mortality rates in glaucoma patients and matched controls from a large population screening as well as glaucoma patients diagnosed through routine clinical examination (self-selected patients)...
Diurnal IOP fluctuation: not an independent risk factor for glaucomatous visual field loss in high-risk ocular hypertensionBoel Bengtsson
Department of Ophthalmology, Malmo University Hospital, Lund University, 20502, Malmo, Sweden
Graefes Arch Clin Exp Ophthalmol 243:513-8. 2005..To establish whether intraocular pressure (IOP) fluctuations contribute to the risk of developing glaucoma in patients with high-risk ocular hypertension...
Visual fields correlate better than visual acuity to severity of diabetic retinopathyB Bengtsson
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, 20502, Malmo, Sweden
Diabetologia 48:2494-500. 2005..We compared the outcomes of perimetric and visual acuity tests in patients with diabetic retinopathy...
Electrophysiology and ocular blood flow in a family with dominant optic nerve atrophy and a mutation in the OPA1 geneLotta Gränse
Department of Ophthalmology, University Hospital of Lund, Lund, Sweden
Ophthalmic Genet 24:233-45. 2003..To characterize the clinical phenotype, with emphasis on electrophysiology and blood flow measurements, of a family with dominant optic nerve atrophy and an identified mutation in the OPA1 gene...
Machine learning classifiers for glaucoma diagnosis based on classification of retinal nerve fibre layer thickness parameters measured by Stratus OCTDimitrios Bizios
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, Malmoe, Sweden
Acta Ophthalmol 88:44-52. 2010....
Modelling the normal retinal nerve fibre layer thickness as measured by Stratus optical coherence tomographyJesper Leth Hougaard
Department of Clinical Sciences, Ophthalmology, Malmo University Hospital, Lund University, 20502 Malmo, Sweden
Graefes Arch Clin Exp Ophthalmol 244:1607-14. 2006..With this perspective we evaluated the isolated and combined effects of factors potentially affecting the Stratus OCT RNFLT measurements in healthy subjects...
Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trialM Cristina Leske
Department of Preventive Medicine, Stony Brook University School of Medicine, Health Sciences Center, L3 086, Stony Brook, NY 11794 8036, USA
Arch Ophthalmol 121:48-56. 2003..To assess factors for progression in the Early Manifest Glaucoma Trial (EMGT), including the effect of EMGT treatment...
Estimating the rate of progressive visual field damage in those with open-angle glaucoma, from cross-sectional dataAimee Teo Broman
Dana Center for Preventive Ophthalmology and the Glaucoma Service, Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Invest Ophthalmol Vis Sci 49:66-76. 2008..To estimate the rate of visual field progression in open-angle glaucoma (OAG) subjects, by using data from population-based cross-sectional studies...
The nerve fibre layer symmetry test: computerized evaluation of human retinal nerve fibre layer thickness as measured by optical coherence tomographyJesper Leth Hougaard
Department of Ophthalmology, Herlev Hospital, University of Copenhagen, Denmark
Acta Ophthalmol Scand 82:410-8. 2004..To present and test a new interpretative concept, the nerve fibre layer symmetry test (NST), for computerized evaluation of retinal nerve fibre layer thickness (RNFLT) as measured by optical coherence tomography (OCT) in glaucoma...
Predictors of long-term progression in the early manifest glaucoma trialM Cristina Leske
Department of Preventive Medicine, Stony Brook University Medical Center, Stony Brook, New York 11794 8036, USA
Ophthalmology 114:1965-72. 2007..To determine progression factors at the end of the Early Manifest Glaucoma Trial (EMGT) based on all EMGT patients and evaluate separately patients with higher and lower baseline intraocular pressure (IOP; median split)...
Factors for progression and glaucoma treatment: the Early Manifest Glaucoma TrialM Cristina Leskea
Department of Preventive Medicine, Stony Brook University School of Medicine, Stony Brook, New York, USA
Curr Opin Ophthalmol 15:102-6. 2004..EMGT randomized patients with early glaucoma either to argon laser trabeculoplasty plus betaxolol (n = 129) or to no immediate treatment (n = 126) and followed them every 3 months...
Cataract epidemiologyAnders Heijl
Ophthalmology 114:201. 2007
Treatment and vision-related quality of life in the early manifest glaucoma trialLeslie G Hyman
Department of Preventive Medicine, School of Medicine, Stony Brook University, Health Sciences Center, Stony Brook, New York 11794-8036, USA
Ophthalmology 112:1505-13. 2005..However, visual function affected vision-targeted quality of life up to 6 years after Early Manifest Glaucoma Trial enrollment...
Nordic research in ophthalmologyEinar Stefansson
University of Iceland, Reykjavik, Iceland
Acta Ophthalmol Scand 81:556-66. 2003..To provide an overview of some of the current activities in eye research in the Nordic countries...
A placebo-controlled study of retinal blood flow changes by pentoxifylline and metabolites in humansMarie Magnusson
Department of Clinical Pharmacology, Lund University Hospital, Lund, Sweden
Br J Clin Pharmacol 61:138-47. 2006..CONCLUSION: The R-M1 and M5 metabolites of pentoxifylline contributed significantly to the effects of pentoxifylline on retinal blood flow...
The effects of antiglaucoma and systemic medications on ocular blood flowVital P Costa
Glaucoma Service, University of Campinas, Rua Bauru, 40, São Paulo 01248 010, Brazil
Prog Retin Eye Res 22:769-805. 2003..Longitudinal, prospective, randomized trials are needed to investigate the effects of vasoactive substances with no hypotensive effect on the progression of glaucoma...
Research Grants
- EARLY MANIFEST GLAUCOMA TRIALAnders Heijl; Fiscal Year: 2004..It is expected, that the large scale community screening effort to recruit study participants with as yet undetected glaucoma, will require screening of 20,000 to 30,000 Malmo citizens in appropriate age groups. ..
