L Grote

Summary

Country: Sweden

Publications

  1. ncbi Reduced alpha- and beta(2)-adrenergic vascular response in patients with obstructive sleep apnea
    L Grote
    Department of Clinical Pharmacology and Sleep Laboratory, Sahlgrenska University Hospital, Goteborg, Sweden
    Am J Respir Crit Care Med 162:1480-7. 2000
  2. ncbi Mean blood pressure, pulse pressure and grade of hypertension in untreated hypertensive patients with sleep-related breathing disorder
    L Grote
    Sleep Disorders Centre, Department of Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    J Hypertens 19:683-90. 2001
  3. ncbi Association between blood pressure reduction with antihypertensive treatment and sleep apnea activity
    L Grote
    Medizinische Poliklinik, Klinikum der Philipps Universität Marburg, Germany
    Am J Hypertens 13:1280-7. 2000
  4. ncbi Sleep-related breathing disorder is an independent risk factor for systemic hypertension
    L Grote
    Schlafmedizinisches Labor, Medizinische Poliklinik, Universitat Marburg, Marburg, Germany
    Am J Respir Crit Care Med 160:1875-82. 1999
  5. ncbi Sleep-related breathing disorder is an independent risk factor for uncontrolled hypertension
    L Grote
    Department of Clinical Pharmacology, Sahlgrenska University Hospital, Gothenburg, Sweden
    J Hypertens 18:679-85. 2000
  6. ncbi [Nocturnal hypertension and sleep apnea: effect of the ACE inhibitor cilazapril on apnea-induced blood pressure increases during sleep]
    L Grote
    Medizinische Poliklinik, Schlafmedizinisches Labor,
    Pneumologie 49:170-4. 1995
  7. ncbi Cardiovascular effects of mibefradil in hypertensive patients with obstructive sleep apnea
    J Heitmann
    Medizinische Poliklinik, Schlafmedizinisches Labor, Klinikum der Philipps Universität Marburg, Germany
    Eur J Clin Pharmacol 54:691-6. 1998
  8. ncbi [Respiratory function diagnosis during sleep: possibilities and limitations]
    T Penzel
    Medizinische Poliklinik, Philipps Universitat, Marburg
    Pneumologie 51:444-9. 1997
  9. ncbi [Carotid baroreflex in sleep apnea patients]
    J J Klawe
    Medizinische Poliklinik, Schlafmedizinisches Labor,
    Pneumologie 51:744-6. 1997
  10. ncbi [Influence of circadian rhythms on cardiovascular function]
    L Grote
    Sleep Disorders Center, Department of Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    Internist (Berl) 45:994-1005. 2004

Detail Information

Publications13

  1. ncbi Reduced alpha- and beta(2)-adrenergic vascular response in patients with obstructive sleep apnea
    L Grote
    Department of Clinical Pharmacology and Sleep Laboratory, Sahlgrenska University Hospital, Goteborg, Sweden
    Am J Respir Crit Care Med 162:1480-7. 2000
    ..76, p < 0.05). The reduced vascular response to alpha- and beta-receptor stimulation suggests a functional downregulation of vascular sympathoadrenergic receptors in patients with sleep apnea...
  2. ncbi Mean blood pressure, pulse pressure and grade of hypertension in untreated hypertensive patients with sleep-related breathing disorder
    L Grote
    Sleep Disorders Centre, Department of Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    J Hypertens 19:683-90. 2001
    ..To test the hypothesis that sleep-related breathing disorder (SRBD) is associated with increasing severity of cardiovascular risk markers...
  3. ncbi Association between blood pressure reduction with antihypertensive treatment and sleep apnea activity
    L Grote
    Medizinische Poliklinik, Klinikum der Philipps Universität Marburg, Germany
    Am J Hypertens 13:1280-7. 2000
    ..Reduced BP was associated with a weak reduction of AI and a slight increase of HI during REM sleep. It appears that elevated BP contributes only marginally to sleep apnea severity in hypertensive patients with obstructive sleep apnea...
  4. ncbi Sleep-related breathing disorder is an independent risk factor for systemic hypertension
    L Grote
    Schlafmedizinisches Labor, Medizinische Poliklinik, Universitat Marburg, Marburg, Germany
    Am J Respir Crit Care Med 160:1875-82. 1999
    ..SRBD is an independent risk factor for systemic hypertension with an increased likelihood in subjects </= 50 yr of age...
  5. ncbi Sleep-related breathing disorder is an independent risk factor for uncontrolled hypertension
    L Grote
    Department of Clinical Pharmacology, Sahlgrenska University Hospital, Gothenburg, Sweden
    J Hypertens 18:679-85. 2000
    ....
  6. ncbi [Nocturnal hypertension and sleep apnea: effect of the ACE inhibitor cilazapril on apnea-induced blood pressure increases during sleep]
    L Grote
    Medizinische Poliklinik, Schlafmedizinisches Labor,
    Pneumologie 49:170-4. 1995
    ..8 mmHg in NR). Thus, evidence is provided for a clinically relevant blood pressure lowering effect of the drug cilazapril on the stress-induced blood pressure increases accompanying obstructive apnea both in NREM and in REM sleep...
  7. ncbi Cardiovascular effects of mibefradil in hypertensive patients with obstructive sleep apnea
    J Heitmann
    Medizinische Poliklinik, Schlafmedizinisches Labor, Klinikum der Philipps Universität Marburg, Germany
    Eur J Clin Pharmacol 54:691-6. 1998
    ..The objective of this study was to investigate the effects of the new T-selective calcium channel blocker mibefradil on invasively measured blood pressure (BP) and heart rate in hypertensive patients with OSA...
  8. ncbi [Respiratory function diagnosis during sleep: possibilities and limitations]
    T Penzel
    Medizinische Poliklinik, Philipps Universitat, Marburg
    Pneumologie 51:444-9. 1997
    ..These evaluations still need further improvements. Nevertheless they can help to clarify the different types of respiratory regulation present in NREM-, REM-sleep and awake state...
  9. ncbi [Carotid baroreflex in sleep apnea patients]
    J J Klawe
    Medizinische Poliklinik, Schlafmedizinisches Labor,
    Pneumologie 51:744-6. 1997
    ..Thus, OSAS patients constitute a high-risk group for the development of cardiovascular diseases and pathological course of blood pressure during daytime...
  10. ncbi [Influence of circadian rhythms on cardiovascular function]
    L Grote
    Sleep Disorders Center, Department of Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    Internist (Berl) 45:994-1005. 2004
    ..The use of melatonin as an antihypertensive drug has been successfully explored and opens new opportunities for the management of cardiovascular dysfunction and disease from a circadian perspective...
  11. ncbi Hypertension prevalence in obstructive sleep apnoea and sex: a population-based case-control study
    J Hedner
    Sleep Laboratory, Department of Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    Eur Respir J 27:564-70. 2006
    ..The contribution of obstructive sleep apnoea to hypertension risk may be sex dependent and higher in males than in females...
  12. doi The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories
    J Hedner
    ESADA office, Gothenburg University, Centre for Sleep and Vigilance Disorders, Gothenburg, Sweden
    Eur Respir J 38:635-42. 2011
    ..The first cross-sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSA...
  13. ncbi [Invasive and noninvasive techniques for analysis of cardiovascular effects of sleep apnea]
    L Grote
    Sleep Disorders Center, Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    Biomed Tech (Berl) 48:190-6. 2003
    ..This approach may demonstrate the predictive value or superiority of a specific diagnostic parameter in the diagnosis of SDB and its cardiovascular consequences...