Research Topics
| P ErikssonSummaryCountry: Sweden Publications
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Publications
Brominated flame retardants: a novel class of developmental neurotoxicants in our environment?P Eriksson
Department of Environmental Toxicology, Uppsala University, Norbyvägen, Uppsala, Sweden
Environ Health Perspect 109:903-8. 2001..Furthermore, neonatal exposure to PBDE 99 also affected learning and memory functions in adult animals. These are developmental defects that have been detected previously in connection with PCBs...
Neonatal exposure to neurotoxic pesticides increases adult susceptibility: a review of current findingsP Eriksson
Department of Environmental Toxicology, Uppsala University, Sweden
Neurotoxicology 21:37-47. 2000..Our studies indicate that neonatal exposure to pesticides--even in low doses--can potentiate and/or modify the reaction to adult exposure to xenobiotics, and thereby accelerate dysfunctional processes...
Exposure to nicotine during a defined period in neonatal life induces permanent changes in brain nicotinic receptors and in behaviour of adult miceP Eriksson
Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 752 36, Uppsala, Sweden
Brain Res 853:41-8. 2000..At no time during the neonatal period could LA nicotine-binding sites be found following nicotine treatment, but the persistence of this effect was evident only in adult mice exposed on days 10-14...
Neonatal exposure to deca-brominated diphenyl ether (PBDE 209) causes dose-response changes in spontaneous behaviour and cholinergic susceptibility in adult miceN Johansson
Department of Environmental Toxicology, Uppsala University, Norbyvägen 18 A, S 752 36 Uppsala, Sweden
Neurotoxicology 29:911-9. 2008..reduced and/or hypoactive response to nicotine. This shows that PBDE 209 can be as potent as the lower brominated PBDEs in causing developmental neurotoxic defects...
Neonatal exposure to DDT induces increased susceptibility to pyrethroid (bioallethrin) exposure at adult age.--Changes in cholinergic muscarinic receptor and behavioural variablesP Eriksson
Department of Zoophysiology, Uppsala University, Sweden
Toxicology 77:21-30. 1993....
Maze learning and motor activity deficits in adult mice induced by iron exposure during a critical postnatal periodA Fredriksson
University of Uppsala, Department of Neuroscience, Psychiatry Ulleraker, Uppsala, Sweden
Brain Res Dev Brain Res 119:65-74. 2000....
Neurobehavioural defects in adult mice neonatally exposed to nicotine: changes in nicotine-induced behaviour and maze learning performanceE Ankarberg
Evolutionary Biology Center, Department of Environmental Toxicology, Uppsala University, Norbyv 18A, S 752 36 Uppsala, Sweden
Behav Brain Res 123:185-92. 2001....
Neurotoxic effects of two different pyrethroids, bioallethrin and deltamethrin, on immature and adult mice: changes in behavioral and muscarinic receptor variablesP Eriksson
Department of Zoophysiology, Uppsala University, Sweden
Toxicol Appl Pharmacol 108:78-85. 1991..This study further supports that disturbances of the cholinergic system during rapid development in the neonatal mouse can lead to permanent changes in cholinergic and behavioral variables in the animals as adults...
Bioallethrin causes permanent changes in behavioural and muscarinic acetylcholine receptor variables in adult mice exposed neonatally to DDTU Johansson
Department of Environmental Toxicology, Uppsala University, Sweden
Eur J Pharmacol 293:159-66. 1995..An adult exposure to this short-acting pesticide to mice neonatally exposed to DDT leads to irreversible muscarinic acetylcholine receptor changes and behavioural disturbances with additional changes 2 months after the exposure...
Effects of two pyrethroids, bioallethrin and deltamethrin, on subpopulations of muscarinic and nicotinic receptors in the neonatal mouse brainP Eriksson
Department of Zoophysiology, Uppsala University, Sweden
Toxicol Appl Pharmacol 102:456-63. 1990..This study further supports that the cholinergic system under rapid development in the neonatal mouse is sensitive to xenobiotics...
A brominated flame retardant, 2,2',4,4',5-pentabromodiphenyl ether: uptake, retention, and induction of neurobehavioral alterations in mice during a critical phase of neonatal brain developmentP Eriksson
Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 752 36, Uppsala, Sweden
Toxicol Sci 67:98-103. 2002..Thus, the behavioral disturbances observed in adult mice following neonatal exposure to 2,2',4,4',5-pentaBDE are induced during a defined critical period of neonatal brain development...
Differential expression of muscarinic subtype mRNAs after exposure to neurotoxic pesticidesU Talts
Department of Environmental Toxicology, Uppsala University, Sweden
Neurobiol Aging 19:553-9. 1998..The present study indicates that the earlier observed increase in muscarinic receptor density in mice exposed as neonates to DDT and as adults to bioallethrin can be attributed to changes in the expression of m4...
Neonatal exposure to a type-I pyrethroid (bioallethrin) induces dose-response changes in brain muscarinic receptors and behaviour in neonatal and adult miceJ Ahlbom
Department of Zoophysiology, Uppsala University, Sweden
Brain Res 645:318-24. 1994..In these adult mice the behavioural variables 'locomotion' and 'total activity' showed significant (P < or = 0.01) dose-dependent increases at all doses up to and including 0.70 mg/kg b.wt...
Changes in behavior and muscarinic receptor density after neonatal and adult exposure to bioallethrinU Talts
Department of Environmental Toxicology, Uppsala University, Sweden
Neurobiol Aging 19:545-52. 1998..These results indicate that neonatal exposure to bioallethrin has the potential to increase susceptibility of the adult mouse to a new exposure at a dosage that does not have any effect in animals treated neonatally with vehicle...
Neonatal exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) causes neurobehavioural defects in adult miceN Johansson
Department of Environmental Toxicology, Uppsala University, Norbyvägen 18 A, S 752 36 Uppsala, Sweden
Neurotoxicology 29:160-9. 2008..These developmental neurotoxic effects are similar to those we reported earlier for PCBs and PBDEs. This suggests that PFOS and PFOA be included in the group of POPs known to be developmental neurotoxicants...
Clonidine abolishes the adverse effects on apoptosis and behaviour after neonatal ketamine exposure in miceE Pontén
Department of Surgical Sciences, Anaesthesiology and Intensive Care, Uppsala University, Sweden
Acta Anaesthesiol Scand 56:1058-65. 2012..Our purpose is to show that increased apoptosis and behavioural alterations after ketamine exposure during this period may be prevented by clonidine, a compound already used by paediatric anaesthetists for sedation...
Postnatal iron-induced motor behaviour alterations following chronic neuroleptic administration in miceA Fredriksson
Department of Neuroscience and Psychiatry, University of Uppsala, Uppsala, Sweden
J Neural Transm 113:137-50. 2006....
Hereditary absence of complement C5 in adult mice influences Wallerian degeneration, but not retrograde responses, following injury to peripheral nerveL Liu
Department of Neuroscience, Biomedical Center, Uppsala University, Sweden
J Peripher Nerv Syst 4:123-33. 1999..These findings elucidate new aspects on the functional role of the complement system in the peripheral nervous system following peripheral nerve injury...
