Research Topics
Genomes and Genes | G EngstromSummaryCountry: Sweden Publications
| Collaborators
|
Detail Information
Publications
Fatality of future coronary events is related to inflammation-sensitive plasma proteins: a population-based prospective cohort studyGunnar Engstrom
Department of Community Medicine, Malmo University Hospital, S 20502 Malmo, Sweden
Circulation 110:27-31. 2004..Approximately 40% of men suffering a first acute coronary event die the first day; most of them never reach hospital. It is largely unknown whether a low-grade inflammation in healthy men predicts the fatality of future coronary events...
Risk of treatment of peripheral arterial disease is related to inflammation-sensitive plasma proteins: a prospective cohort studyGunnar Engstrom
Department of Community Medicine, Malmo University Hospital, Sweden
J Vasc Surg 40:1101-5. 2004..However, few have studied the prognostic significance of inflammatory markers in asymptomatic subjects, measured many years before the onset of symptomatic PAD requiring treatment (trPAD)...
Lung function and cardiovascular risk: relationship with inflammation-sensitive plasma proteinsG Engstrom
Department of Community Medicine, Malmo University Hospital, Malmo, Sweden
Circulation 106:2555-60. 2002..The inverse relationship between pulmonary function and incidence of cardiovascular disease remains largely unexplained. This prospective study explored the hypothesis of a relationship with inflammation-sensitive plasma proteins...
Long-term effects of inflammation-sensitive plasma proteins and systolic blood pressure on incidence of strokeG Engstrom
Departments of Community Medicine, Malmo University Hospital, Malmo, Sweden
Stroke 33:2744-9. 2002..The present study investigated the relationships between inflammation-sensitive plasma proteins (ISPs) and systolic blood pressure (SBP), as well as the joint long-term effects of ISP and SBP on incidence of stroke...
Blood pressure increase and incidence of hypertension in relation to inflammation-sensitive plasma proteinsGunnar Engstrom
Department of Community Medicine, Malmo University Hospital, Malmo, Sweden
Arterioscler Thromb Vasc Biol 22:2054-8. 2002..This study explored the hypothesis that ISPs are associated with future hypertension and age-related blood pressure increase...
Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: a population-based studyGunnar Engstrom
Department of Community Medicine, Malmo University Hospital, Sweden
Diabetes 52:442-7. 2003..High ISP levels increased the cardiovascular risk similarly in diabetic as compared with nondiabetic men...
Lung function, insulin resistance and incidence of cardiovascular disease: a longitudinal cohort studyG Engstrom
Department of Community Medicine, University of Lund, Malmo University Hospital, Malmo, Sweden
J Intern Med 253:574-81. 2003....
Inflammation-sensitive plasma proteins are associated with future weight gainGunnar Engstrom
Department of Community Medicine, Lund University, Malmo, Sweden
Diabetes 52:2097-101. 2003..Elevated ISP levels predict a large weight gain in middle-aged men. This relation could contribute to the relation between inflammation, the metabolic syndrome, and cardiovascular disease...
Inflammation-sensitive plasma proteins and incidence of myocardial infarction in men with low cardiovascular riskGunnar Engstrom
Department of Community Medicine, Malmo University Hospital, S 20502 Malmo, Sweden
Arterioscler Thromb Vasc Biol 23:2247-51. 2003..This prospective study explored whether incidence of MI in nonsmoking, nondiabetic men with normal blood pressure and serum lipids is related to inflammation-sensitive plasma proteins (ISPs)...
Incidence of fatal or repaired abdominal aortic aneurysm in relation to inflammation-sensitive plasma proteinsGunnar Engstrom
Department of Community Medicine, Lund University, Malmo University Hospital, Sweden
Arterioscler Thromb Vasc Biol 24:337-41. 2004..004). CONCLUSIONS: The incidence of fatal or repaired AAA is associated with the ISP levels. In this population-based study, elevated ISPs could be observed many years before the clinical manifestation of disease...
Complement C3 is a risk factor for the development of diabetes: a population-based cohort studyGunnar Engstrom
Department of Community Medicine, Lund University, Sweden
Diabetes 54:570-5. 2005..We concluded that the risk of developing diabetes is related to levels of complement C3...
Incidence of obesity-associated cardiovascular disease is related to inflammation-sensitive plasma proteins: a population-based cohort studyGunnar Engstrom
Department of Community Medicine, Malmo University Hospital, Malmo, Sweden
Arterioscler Thromb Vasc Biol 24:1498-502. 2004..This population-based study explored whether inflammation-sensitive plasma proteins (ISPs) modify the cardiovascular risk in overweight or obese men...
Marital dissolution is followed by an increased incidence of strokeGunnar Engstrom
Department of Community Medicine, Malmo University Hospital, Malmo, Sweden
Cerebrovasc Dis 18:318-24. 2004..The relation between marital status and incidence of haemorrhagic and ischaemic stroke is unclear. It is largely unknown whether the risk of stroke is increased the first years after divorce or death of spouse...
Risk of developing diabetes is inversely related to lung function: a population-based cohort studyG Engstrom
Department of Community Medicine, University Hospital, Malmo, Sweden
Diabet Med 19:167-70. 2002..To investigate whether reduced lung function is a risk factor for developing diabetes...
Effects of cholesterol and inflammation-sensitive plasma proteins on incidence of myocardial infarction and stroke in menG Engstrom
Department of Community Medicine, Malmo University Hospital, Malmo, Sweden
Circulation 105:2632-7. 2002..This study explored whether the cholesterol-related incidence of stroke and myocardial infarction is modified by plasma markers of inflammation in a large, population-based cohort with a long follow-up...
Hypertensive men who exercise regularly have lower rate of cardiovascular mortalityG Engstrom
Department of Community Medicine, Malmo University Hospital, Lund University, Sweden
J Hypertens 17:737-42. 1999..Regular exercise has been associated in prospective studies with reduced incidence of cardiovascular disease (CVD) and death...
Subjective well-being associated with improved survival in smoking and hypertensive menG Engstrom
Department of Community Medicine, Malmo University Hospital, Lund University, Sweden
J Cardiovasc Risk 6:257-61. 1999..The purpose of the present study was to determine to what extent self-rated perception of health modifies the survival rates in men at risk from tobacco smoking or hypertension...
Reduced cerebrospinal HVA concentrations and HVA/5-HIAA ratios in suicide attempters. Monoamine metabolites in 120 suicide attempters and 47 controlsG Engstrom
Department of Clinical Neuroscience, Psychiatry Section, University Hospital, Lund, Sweden
Eur Neuropsychopharmacol 9:399-405. 1999..The results suggest that low HVA levels and altered relationships between the monoamine metabolites are associated with suicidal behaviour...
Ventricular arrhythmias during 24-h ambulatory ECG recording: incidence, risk factors and prognosis in men with and without a history of cardiovascular diseaseG Engstrom
Department of Community Health Medicine, Malmo University, Sweden
J Intern Med 246:363-72. 1999..To study incidence, prognosis and risk factors of ventricular arrhythmias in men with and without asymptomatic non-invasively detected cardiovascular disease (CVD)...
Respiratory decline in smokers and ex-smokers--an independent risk factor for cardiovascular disease and deathG Engstrom
Department of Community Medicine, Malmo University Hospital, Sweden
J Cardiovasc Risk 7:267-72. 2000..Our objective was to assess whether this variation is related to rate of decline of respiratory function...
Cardiac arrhythmias and stroke: increased risk in men with high frequency of atrial ectopic beatsG Engstrom
Department of Community Medicine, Malmö University Hospital Sweden
Stroke 31:2925-9. 2000..We sought to study whether atrial and ventricular arrhythmias assessed during a 24-hour ambulatory ECG registration are associated with incidence of stroke...
Increased incidence of myocardial infarction and stroke in hypertensive men with reduced lung functionG Engstrom
Department of Community Medicine, Malmo University Hospital, Sweden
J Hypertens 19:295-301. 2001..Although hypertension is associated with increased cardiovascular risk, many individuals remain free from disease. This study is aimed to investigate whether this variation in individual susceptibility is associated with lung function...
Geographic distribution of stroke incidence within an urban population: relations to socioeconomic circumstances and prevalence of cardiovascular risk factorsG Engstrom
Department of Community Medicine, Malmo University Hospital, Malmo, Sweden
Stroke 32:1098-103. 2001..The present study from the city of Malmö, Sweden, sought to investigate whether incidence of stroke in residential areas is related to prevalence of cardiovascular risk factors and socioeconomic circumstances...
Occurrence and prognostic significance of ventricular arrhythmia is related to pulmonary function: a study from "men born in 1914," Malmö, SwedenG Engstrom
Departments of Community Medicine, Clinical Physiology, Malmo University Hospital, Malmo, Sweden
Circulation 103:3086-91. 2001..Reduced lung function has been associated with increased rates of myocardial infarction. Whether the occurrence and prognostic significance of ventricular arrhythmia is related to lung function is largely unknown...
Blood pressure increase between 55 and 68 years of age is inversely related to lung function: longitudinal results from the cohort study 'Men born in 1914'G Engstrom
Department of Community Medicine, University Hospital, Malmo, Sweden
J Hypertens 19:1203-8. 2001..Although age is associated with increasing blood pressure, there is a substantial heterogeneity within a certain birth cohort. Whether increase in systolic and diastolic blood pressure is related to pulmonary function is largely unknown...
Risk of myocardial infarction and stroke in smokers is related to plasma levels of inflammation-sensitive proteinsP Lind
Department of Internal Medicine, Malmo University Hospital, S 20502 Malmo, Sweden
Arterioscler Thromb Vasc Biol 24:577-82. 2004....
Asymptomatic leg and carotid atherosclerosis in smokers is related to degree of ventilatory capacity: longitudinal and cross-sectional results from 'Men born in 1914', SwedenG Engstrom
Department of Community Medicine, Malmo University Hospital, S 20502, Malmo, Sweden
Atherosclerosis 155:237-43. 2001..We conclude that the risk of developing atherosclerosis is associated with the degree of ventilatory capacity. The results suggest that in smokers, reduced lung function is a marker of susceptibility for atherosclerosis...
Weight gain in relation to plasma levels of complement factor 3: results from a population-based cohort studyG Engstrom
Department of Clinical Sciences MFC Ing 59 Lund University, Malmo University Hospital, S 20502, Malmo, Sweden
Diabetologia 48:2525-31. 2005..Cross-sectional studies of humans have reported correlations between C3 and obesity. This longitudinal study explored whether C3 predicts a large weight gain in middle-aged men...
Survival rate 28 days after hospital admission with first myocardial infarction. Inverse relationship with socio-economic circumstancesS Gerward
Department of Clinical Sciences in Malmo, Epidemiological Research Group, Malmo University Hospital, Malmo, Sweden
J Intern Med 259:164-72. 2006....
Prevalence and prognostic significance of asymptomatic peripheral arterial disease in 68-year-old men with diabetes. Results from the population study 'Men born in 1914' from Malmö, SwedenM Ogren
Department of Community Medicine, Division of Epidemiology, Lund University, Malmo University Hospital, Malmo, Sweden
Eur J Vasc Endovasc Surg 29:182-9. 2005....
Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and deathB Hedblad
Department of Medicine and Department of Community Medicine, Lund University, Malmo University Hospital, Malmo, Sweden
Diabet Med 19:470-5. 2002..To compare the incidence of myocardial infarction and death in non-diabetic subjects with and without insulin resistance...
Obesity and myocardial infarction--vulnerability related to occupational level and marital status. A 23-year follow-up of an urban male Swedish populationB Hedblad
Department of Community Medicine, Lund University, Malmo University Hospital, Malmo, Sweden
J Intern Med 252:542-50. 2002..People, who are single, have a blue-collar job or low income have an increased cardiovascular risk. This study on myocardial infarction sought to explore whether the socio-economic pattern of disease has any relationship with obesity...
Plasma levels of complement C3 is associated with development of hypertension: a longitudinal cohort studyG Engstrom
Department of Clinical Science, Malmo University Hospital, Lund University, Malmo, Sweden
J Hum Hypertens 21:276-82. 2007..It is concluded that C3 in plasma is associated with future blood pressure increase and development of hypertension...
Tobacco and myocardial infarction in middle-aged women: a study of factors modifying the riskE Janzon
Department of Community Medicine, Division of Epidemiology, Lund University, Malmo University Hospital, Malmo, Sweden
J Intern Med 256:111-8. 2004..This study explored how the risk of MI in current and former smokers is modified by other cardiovascular risk factors...
Reduced lung function predicts increased fatality in future cardiac events. A population-based studyG Engstrom
Department of Clinical Sciences, Malmo University Hospital, Lund University, Malmo, Sweden
J Intern Med 260:560-7. 2006..This study explored whether reduced forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV(1)) in initially healthy men is related to the fatality of the future coronary events...
Asymptomatic leg atherosclerosis is reduced by regular physical activity. Longitudinal results from the cohort "men born in 1914"G Engstrom
Division of Epidemiology, Department of Community Medicine, Malmo University Hospital, Lund University, Malmo, Sweden
Eur J Vasc Endovasc Surg 21:502-7. 2001..To study whether physical activity is associated with reduced occurrence of asymptomatic leg atherosclerosis...
Soluble urokinase plasminogen activator receptor in plasma is associated with incidence of CVD. Results from the Malmö Diet and Cancer StudyM Persson
Department of Clinical Sciences Medicine, Malmo, Lund University, Sweden
Atherosclerosis 220:502-5. 2012..The aim of this study was to explore the relationship between suPAR, cardiovascular disease (CVD) risk factors and incidence of CVD...
Plasma markers of inflammation and incidence of hospitalisations for COPD: results from a population-based cohort studyG Engstrom
Department of Clinical Sciences, University of Lund, Lund, Sweden
Thorax 64:211-5. 2009..This population-based study explored whether raised levels of five inflammation-sensitive plasma proteins (ISPs) predicted hospital admissions for COPD during 25 years of follow-up...
Trends in long-term survival after myocardial infarction: less favourable patterns for patients from deprived areasG Engstrom
Department of Community Medicine, Malmo University Hospital, Malmo, Sweden
J Intern Med 248:425-34. 2000..However, studies on long-term survival are not unequivocally in favour of an improved long-term prognosis. This study aimed to analyse trends in 3-year survival in relation to sex, age and socioeconomic level of residential area...
Fatality of acute coronary events in relation to hypertension and low-grade inflammation: a population-based cohort studyG Engstrom
Department of Clinical Sciences in Malmo, Lund University, Malmo University Hospital, Malmo, Sweden
J Hum Hypertens 20:581-6. 2006..The influence of ISPs on the case-fatality rate seems to be most important in men with normal BP...
Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort studyL S Lohmander
Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Ann Rheum Dis 68:490-6. 2009..To determine in a prospective population-based cohort study relationships between different measures of body mass and the incidence of severe knee and hip osteoarthritis defined as arthroplasty of knee or hip due to osteoarthritis...
Influence of obesity on cardiovascular risk. Twenty-three-year follow-up of 22,025 men from an urban Swedish populationS Jonsson
Department of Community Medicine, , Malm, Sweden
Int J Obes Relat Metab Disord 26:1046-53. 2002..The preventive potential of these associations should be evaluated in controlled trials...
Geographical pattern of female deaths from myocardial infarction in an urban population: fatal outcome out-of-hospital related to socio-economic deprivationP Tydén
Department of Community Medicine, Malmo University Hospital, Lund University, Malmo, Sweden
J Intern Med 250:201-7. 2001....
Myocardial infarction in an urban population: worse long term prognosis for patients from less affluent residential areasP Tydén
Department of Community Medicine, Malmo University Hospital, Lund University, Malmo, Sweden
J Epidemiol Community Health 56:785-90. 2002....
Area social characteristics and carotid atherosclerosisM Rosvall
Department of Health Sciences, Lund University, Malmo University Hospital, Malmo, Sweden
Eur J Public Health 17:333-9. 2007..To explore the effect of social characteristics of residential areas on carotid atherosclerosis prevalence...
Risk of haemorrhagic stroke in patients with oral anticoagulation compared with the general populationA Själander
Department of Coagulation Disorders, Malmo University Hospital, University of Lund, Lund, Sweden
J Intern Med 254:434-8. 2003..To compare the incidence of haemorrhagic stroke (HS), and the risk of fatal outcome after HS in patients with oral anticoagulation (OA) treatment and in the general population...
The role of low grade inflammation as measured by C-reactive protein levels in the explanation of socioeconomic differences in carotid atherosclerosisM Rosvall
Department of Health Sciences, Lund University, Malmo, Sweden
Eur J Public Health 17:340-7. 2007..The role of inflammation as part of the explanation of socioeconomic differences in carotid atherosclerosis has not been specifically investigated...
C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort studyG Engstrom
AstraZeneca R and D, Lund, Sweden
Osteoarthritis Cartilage 17:168-73. 2009..To explore the relationships between C-reactive protein (CRP), metabolic syndrome (MetS) and incidence of severe knee or hip osteoarthritis (OA) in a prospective study...
The Pro12Ala polymorphism of the PPARG gene is not associated with the metabolic syndrome in an urban population of middle-aged Swedish individualsM Montagnana
Department of Clinical Sciences, Lund University, University Hospital of Malmo, Malmo, Sweden
Diabet Med 25:902-8. 2008....
Incident coronary events and case fatality in relation to common carotid intima-media thicknessM Rosvall
Department of Community Medicine, Lund University, Malmo University Hospital, Malmo, Sweden
J Intern Med 257:430-7. 2005..To evaluate the incidence of coronary events (CE) and case fatality in relation to common carotid intima-media thickness (IMT) and carotid plaque over a median follow up of 7 years...
Changes in blood pressure and body weight following smoking cessation in womenE Janzon
Department of Community Medicine, Division of Epidemiology, Lund University, Malmo University Hospital, Malmo, Sweden
J Intern Med 255:266-72. 2004..This study compared the development of weight and blood pressure in female never smokers, continuing smokers and smokers who quit smoking...
A myocardial infarction genetic risk score is associated with markers of carotid atherosclerosisV Hamrefors
Department of Clinical Sciences, Lund University, Malmo, Sweden
J Intern Med 271:271-81. 2012..To assess whether or not a genetic risk score that was previously shown to be associated with myocardial infarction (MI) and coronary artery disease (CAD) is also associated with markers of carotid atherosclerosis...
Sex differences in the relationships between BMI, WHR and incidence of cardiovascular disease: a population-based cohort studyC Li
Department of Clinical Sciences in Malmo, Epidemiological Research Group, Malmo University Hospital, Malmo, Sweden
Int J Obes (Lond) 30:1775-81. 2006..The present study explored whether regional fat distribution, as measured by waist-hip ratio (WHR), could modify the impact of BMI on the risk of CVD in men and women...
Adaptive behavior in stressful situations and stroke incidence in hypertensive men: results from prospective cohort study "men born in 1914" in Malmö, SwedenL Andre-Petersson
Division of Epidemiology, Department of Community Medicine, Malmo University Hospital, Lund University, Malmo, Sweden
Stroke 32:1712-20. 2001..The aim of the present study was to analyze whether adaptation in a stressful situation was associated with the incidence of stroke in hypertensive men...
Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysisJ G Smith
Department of Cardiology, Lund University, Lund, Sweden
J Intern Med 272:573-82. 2012..Polymorphisms associated with atrial fibrillation (AF) have shown relatively large risk estimates, but the robustness of such estimates across populations and study designs has not been investigated...
Total and differential leucocyte counts in relation to incidence of stroke subtypes and mortality: a prospective cohort studyE Zia
Department of Neurology, Skane University Hospital, Malmo, Sweden
J Intern Med 272:298-304. 2012..We evaluated the associations between total leucocyte count (TLC) as well as leucocyte subtypes and the incidence of and mortality caused by different stroke subtypes...
Plasma procalcitonin and the risk of cardiovascular events and death: a prospective population-based studyA Schiopu
Department of Clinical Sciences, Lund University, Skåne University Hospital Malmö, Malmo, Sweden
J Intern Med 272:484-91. 2012..We evaluated the ability of PCT to predict future cardiovascular events in a population of apparently healthy individuals...
CSF biomarkers in suicide attempters--a principal component analysisD Lindqvist
Department of Clinical Sciences, Section of Psychiatry, Psychoimmunology Unit, Lund University Hospital, Kioskgatan 19, Lund, Sweden
Acta Psychiatr Scand 124:52-61. 2011..The objective of the present study was to identify biological patterns (factors) among 20 cerebrospinal fluid (CSF) biomarkers in suicide attempters and subsequently analyse their association with suicidal behaviour...
The metabolic syndrome and incidence of cardiovascular disease in non-diabetic subjects--a population-based study comparing three different definitionsP M Nilsson
Section of Medicine, Department of Clinical Sciences Medicine, University Hospital, Malmo, Sweden
Diabet Med 24:464-72. 2007..The aim of this population-based cohort study was to compare prevalence rates and the prediction of cardiovascular disease (CVD) using different definitions of MetS...
Incidence of stroke is related to carotid IMT even in the absence of plaqueM Rosvall
Department of Community Medicine, Lund University, Malmo University Hospital, SE 205 02 Malmo, Sweden
Atherosclerosis 179:325-31. 2005..The carotid intima-media thickness (IMT) has been associated with incidence of stroke. Whether this association is independent of carotid plaque is controversial...
Social characteristics of seasonal affective disorder patients: comparison with suicide attempters with non-seasonal major depression and other mood disorder patientsB P G Pendse
Lund Suicide Research Centre, Division of Psychiatry, Department of Clinical Neuroscience, Lund University Hospital, 221 85 Lund, Sweden
Eur Psychiatry 18:36-9. 2003..Thus, the results indicate a considerable social impairment in SAD...
Orthostatic hypotension and long-term incidence of atrial fibrillation: the Malmö Preventive ProjectA Fedorowski
Center for Emergency Medicine, Skane University Hospital, Malmo, Sweden
J Intern Med 268:383-9. 2010..However, the role of OH in the development of atrial fibrillation has not been studied...
Impulse oscillometry may be of value in detecting early manifestations of COPDS Frantz
Clinical Physiology and Nuclear Medicine Unit, Department of Clinical Sciences, Malmo, Lund University, Sweden
Respir Med 106:1116-23. 2012....
Leg blood flow and long-term cardiovascular prognosis in men with typical and atypical intermittent claudicationM Ogren
Department of Community Medicine, Division of Epidemiology, Lund University, , S-205 02 Malm, Sweden
Eur J Vasc Endovasc Surg 26:272-9. 2003..To properly assess the prognosis, non-invasive assessment of PAD should be used in addition to questionnaires...
