- Adipose tissue metabolism in 2012: Adipose tissue plasticity and new therapeutic targetsSven Enerback
University of Gothenburg, Department of Medical and Clinical Genetics, Institute of Biomedicine, Sahlgrenska Academy, Sweden
Nat Rev Endocrinol 9:69-70. 2013..A bipotential adipocyte progenitor giving rise to both brown and white adipocytes has also been identified...
- Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazoneJoakim Håkansson
Department of Medical and Clinical Genetics, Institute of Biomedicine University of Gothenburg, Goteborg, Sweden
Diabetol Metab Syndr 3:32. 2011..abstract:..
- Brown adipose tissue in humansS Enerback
Department of Medical and Clinical Genetics, Goteborg University, Goteborg, Sweden
Int J Obes (Lond) 34:S43-6. 2010..Ectopic triglyceride storage at these locations is associated with initiation of insulin resistance and, ultimately, development of type 2 diabetes...
- Human brown adipose tissueSven Enerback
Department of Medical and Clinical Genetics, Institute of Biomedicine, University of Gothenburg, Medicinaregatan 9A, P O Box 440, SE 40530 Goteborg, Sweden
Cell Metab 11:248-52. 2010..The BAT organ is unique in that it has evolved to safely dissipate large amounts of chemical energy--a quality that might be harnessed to help humans deal with a dangerously hypercaloric environment and still remain in good health...
- Insulin resistance and type 2 diabetes--an adipocentric viewAnna Cederberg
Medical Genetics, Department of Medical Biochemistry, Goteborg University, Box 440, SE 405 30 Goteborg, Sweden
Curr Mol Med 3:107-25. 2003..This review sets out to discuss the adipocyte and its role in metabolism as well as the consequences of a metabolic situation, in which the adipocyte has lost its fat storing monopoly...
- Brown adipose tissue--a new role in humans?Martin E Lidell
Department of Medical and Clinical Genetics, Institute of Biomedicine, University of Gothenburg, Box 440, SE 40530 Gothenburg, Sweden
Nat Rev Endocrinol 6:319-25. 2010..Whether or not brown adipose tissue will be useful in the battle against obesity remains to be seen. However, this possibility is certainly well worth exploring...
- Reduced expression of FOXC2 and brown adipogenic genes in human subjects with insulin resistanceXiaolin Yang
The Lundberg Laboratory for Diabetes Research, Department of Internal Medicine, Sahlgrenska University Hospital, , Sweden
Obes Res 11:1182-91. 2003..DISCUSSION: Our results suggest that a reduced brown adipose phenotype is associated with insulin resistance and that a basal brown adipose phenotype may be important for maintaining normal insulin sensitivity...
- A compact, flexible and cheap system for acquiring sequence data from autoradiograms with a digitizer and transferring it to an arbitrary host computerS Sjoberg
Department of Medical Biochemistry, University of Gothenburg, Sweden
Comput Appl Biosci 5:41-6. 1989..The gel reading algorithm described is fast, accurate and simple and the file transfer relies on the safe and well-known Kermit programs...
- FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistanceA Cederberg
Medical Genetics, Department of Medical Biochemistry, Goteborg University, Box 440, SE 405 30, Goteborg, Sweden
Cell 106:563-73. 2001....
- The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial functionMartin E Lidell
Department of Medical and Clinical Genetics, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Diabetes 60:427-35. 2011..These findings prompted us to further investigate the role of Foxc2 in the regulation of genes of fundamental importance for metabolism and mitochondrial function...
- Overexpression of Foxf2 in adipose tissue is associated with lower levels of IRS1 and decreased glucose uptake in vivoRickard Westergren
Dept of Medical and Clinical Genetics, Institute of Biomedicine, Univ of Göteborg, Sweden
Am J Physiol Endocrinol Metab 298:E548-54. 2010..Foxf2 and its downstream target genes can provide new insights with regard to identification of novel therapeutic targets...